EKS-TAR-00275

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00275

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF2	439.3	2.1E-131	107	455	349

Status

Unreviewed

Ensembl Protein

ENSTRUP00000020227

UniProt Accession

H2T6D7;

Protein Name

Protein Synonyms/Alias

Gene Name

PINK1

Gene Synonyms/Alias

PINK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000008101	ENSTRUP00000020226	ENSTRUT00000020310
ENSTRUG00000008101	ENSTRUP00000020227	ENSTRUT00000020311

Organism

Takifugu rubripes

Functional Description

Protein Length

528

Protein Sequence
(FASTA)

MSLRHAVSRG LEWGRSLLQP GLLKSGGRLG LAAQLQSAAF RRGFGGGAAR NRAVFLAFGL 60

GVGLIEQQLE EDRKSDAACQ EIQAVFKRKR FPAPLRPFTS GYKLEDYVIG NQIGKGSNAA 120

VYEAAASFAP LKESEASVVE LKDGEEPSAR PLTCCSLRNF PLAIKMMWNF GAGSSSEAIL 180

KSMSQELVPA GPSALNVQDQ VVLDGHFGAV RGLAAHPNVI SVCRVFTARV PLLPGALEEY 240

PDMLPARLNP AGLGNDRTLF LVMKNYPLTL RRFLAGSRPS PRQQALMVLQ LLEAVDHLCR 300

QGVAHRDLKS DNVLLELDPA GDPRLVVSDF GCCLSQSDCS LQLPFGSMWV SRGGNVSLMA 360

PEVIGAVPGA SVVIDYSKAD AWAVGAVAFE ICGRPNPFYG GAGLESGRYQ ETQLPALPSD 420

VPADVQLVIR LLLRRNPEKR PSARVAANML HLSLWGRTVL DHLDGAGTRR LVDWLLCQSA 480

LVLLKGRRGP RGDTVEAELQ RCFLAHLELE ELRTAVGFLL CGPGRPAC 528

Nucleotide Sequence
(FASTA)

ATGTCTCTGA GACACGCTGT GAGCCGGGGC CTGGAGTGGG GCCGCTCCCT CCTTCAGCCG 60

GGGCTCCTCA AATCTGGGGG CCGACTGGGC CTGGCCGCTC AGCTCCAGTC CGCCGCCTTC 120

AGGAGAGGCT TCGGCGGGGG GGCAGCGCGG AACAGGGCCG TGTTCCTGGC CTTCGGTCTC 180

GGCGTGGGGC TCATCGAGCA GCAGCTGGAA GAGGACAGAA AGAGCGACGC GGCCTGTCAG 240

GAGATCCAGG CTGTTTTTAA GAGGAAACGC TTCCCGGCGC CACTCCGGCC GTTCACCTCC 300

GGATACAAAC TGGAGGATTA TGTCATCGGG AACCAGATCG GGAAAGGATC CAACGCCGCT 360

GTGTATGAGG CCGCGGCCTC GTTCGCCCCC CTGAAGGAGA GCGAGGCCTC CGTGGTGGAG 420

CTGAAGGACG GTGAAGAGCC AAGCGCTCGA CCTCTGACCT GCTGCTCGCT CAGAAACTTC 480

CCTCTGGCCA TCAAGATGAT GTGGAACTTC GGGGCGGGCT CGTCCAGCGA GGCCATATTA 540

AAGTCCATGT CCCAGGAGCT GGTGCCCGCA GGTCCTTCAG CCTTGAATGT GCAGGACCAG 600

GTTGTCCTGG ACGGGCACTT TGGAGCCGTG AGAGGTCTGG CAGCTCACCC CAACGTCATC 660

AGCGTGTGCC GGGTGTTCAC GGCCCGGGTC CCGCTGCTCC CAGGGGCCCT GGAGGAGTAT 720

CCGGACATGC TCCCGGCCCG GCTCAACCCT GCCGGTCTGG GCAACGACCG CACGCTCTTC 780

CTGGTCATGA AGAATTACCC CCTCACGCTG CGACGGTTCC TGGCCGGGTC CCGGCCCAGC 840

CCCAGGCAGC AGGCCCTGAT GGTGCTGCAG CTCCTGGAGG CCGTCGACCA TCTGTGCAGA 900

CAAGGCGTCG CCCACAGGGA CCTCAAGTCT GACAACGTGC TGCTGGAGCT GGATCCCGCT 960

GGTGACCCTC GTCTGGTGGT CAGTGACTTT GGCTGCTGCC TGTCTCAGAG CGACTGCAGC 1020

CTGCAGCTGC CCTTCGGCAG CATGTGGGTC AGCAGGGGGG GCAACGTGTC CCTCATGGCC 1080

CCCGAGGTGA TCGGCGCGGT CCCTGGAGCC AGCGTGGTGA TTGACTACAG CAAAGCGGAC 1140

GCGTGGGCCG TGGGGGCCGT GGCCTTTGAG ATCTGTGGGC GGCCCAATCC GTTCTACGGG 1200

GGGGCGGGGC TAGAGAGCGG GCGGTACCAG GAGACCCAGC TTCCCGCTCT GCCCTCCGAC 1260

GTCCCTGCAG ACGTGCAGCT CGTGATCCGT CTGCTCCTCA GGAGGAACCC GGAGAAGCGT 1320

CCCAGCGCAC GTGTGGCTGC CAACATGCTG CACCTCAGCC TGTGGGGACG GACGGTCCTG 1380

GACCACCTGG ACGGTGCCGG GACCAGGCGC CTGGTGGACT GGCTGCTGTG CCAGTCGGCC 1440

CTGGTGCTCC TGAAGGGGCG CCGCGGGCCG CGAGGCGACA CGGTGGAGGC GGAGCTTCAG 1500

AGGTGCTTCC TGGCTCACCT GGAGCTGGAG GAGCTGCGCA CCGCCGTGGG CTTCCTGCTG 1560

TGTGGGCCGG GGCGTCCGGC CTGC 1584

Domain Profile

S: 1     yligealgkgcnaavyeatlatldqelekakhlgll.gkevtvvlaeidqesavaakkfp  59

         y ig+ +gkg naavyea  + ++ + ++a  + l  g+e     + + +    + ++fp

Q: 107   YVIGNQIGKGSNAAVYEAAASFAPLKESEASVVELKdGEE-----PSARPLTCCSLRNFP  161

         89*****************999999888887777663444.....45678889999****

S: 60    laiklmfnieadssseallksmsqelvpasrva........ldgeygavpkllakhPniv  111

         laik+m+n+ a+sssea+lksmsqelvpa   a        ldg++gav+  la hPn++

Q: 162   LAIKMMWNFGAGSSSEAILKSMSQELVPAGPSAlnvqdqvvLDGHFGAVRG-LAAHPNVI  220

         ****************************97665444455558999999998.9*******

S: 112   rvlrafidsvkllPdalldyPdalparlypeglgegktlylvmkrydqtlreylesqdrs  171

          v r+f+  v+llP+al++yPd+lparl+p glg+++tl+lvmk+y+ tlr +l    +s

Q: 221   SVCRVFTARVPLLPGALEEYPDMLPARLNPAGLGNDRTLFLVMKNYPLTLRRFLAGSRPS  280

         ************************************************************

S: 172   trlaalllaqlleavdhlvkhgvahrdlksdnilveldddeiPvlviadfGCcladkvdg  231

         +r++al+++qlleavdhl ++gvahrdlksdn+l+eld+ + P lv++dfGCcl++   +

Q: 281   PRQQALMVLQLLEAVDHLCRQGVAHRDLKSDNVLLELDPAGDPRLVVSDFGCCLSQSDCS  340

         ************************************************************

S: 232   lrlpyessevdkGGnaalmaPeistavpGpsavinyekadtWavGalayeifglsnPfyg  291

         l+lp+ s  v++GGn +lmaPe+  avpG s+vi+y+kad+WavGa+a+ei g+ nPfy

Q: 341   LQLPFGSMWVSRGGNVSLMAPEVIGAVPGASVVIDYSKADAWAVGAVAFEICGRPNPFY-  399

         ***********************************************************.

S: 292   egkaslesasyqeaqlPalpesvppelrqlvydllkreaskrvsadiaanvlqlslf  348

          g a les  yqe+qlPalp+ vp +++ +++ ll+r+++kr+sa++aan+l+lsl+

Q: 400   -GGAGLESGRYQETQLPALPSDVPADVQLVIRLLLRRNPEKRPSARVAANMLHLSLW  455

         .6789***************************************************9

Domain Sequence
(FASTA)

YVIGNQIGKG SNAAVYEAAA SFAPLKESEA SVVELKDGEE PSARPLTCCS LRNFPLAIKM 60

MWNFGAGSSS EAILKSMSQE LVPAGPSALN VQDQVVLDGH FGAVRGLAAH PNVISVCRVF 120

TARVPLLPGA LEEYPDMLPA RLNPAGLGND RTLFLVMKNY PLTLRRFLAG SRPSPRQQAL 180

MVLQLLEAVD HLCRQGVAHR DLKSDNVLLE LDPAGDPRLV VSDFGCCLSQ SDCSLQLPFG 240

SMWVSRGGNV SLMAPEVIGA VPGASVVIDY SKADAWAVGA VAFEICGRPN PFYGGAGLES 300

GRYQETQLPA LPSDVPADVQ LVIRLLLRRN PEKRPSARVA ANMLHLSLW 349

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>