EKS-TAR-00577

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00577

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/MAPK	410.2	9.8E-123	25	307	283

Status

Unreviewed

Ensembl Protein

ENSTRUP00000021639

UniProt Accession

H2TAE9;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPK13

Gene Synonyms/Alias

MAPK13;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000008627	ENSTRUP00000021639	ENSTRUT00000021727
ENSTRUG00000008627	ENSTRUP00000021640	ENSTRUT00000021728
ENSTRUG00000008627	ENSTRUP00000021641	ENSTRUT00000021729
ENSTRUG00000008627	ENSTRUP00000021642	ENSTRUT00000021730

Organism

Takifugu rubripes

Functional Description

Protein Length

364

Protein Sequence
(FASTA)

CIMEAHAHFS REEINNTVWE VPEKYTRLKQ IGTGAYGSVC STINEKTKEK VAIKKLHRPF 60

QSEIFAKRAY RELRLLKHMK HENVIGLLDV FTPALGLDEM QDFYLVMPYM FTDLSKVRGP 120

LSEDKVQFLI YQTLCGLRYI HKAGIIHRDL KPGNLAVNQD CELKILDFGL ARSADAEMTG 180

YVVTRWYRAP EVILNWMHYT QTVDIWSVGC IMAEMIHGKT LFKGKDYMDQ LTQIMKVTGV 240

PGPEFIQKLD SIEAKNYVKA LPRYPRKDFS TLFPKASAKG IDLLEKMLVL DGDERLTAEL 300

ALEHSYFDSL RDPDDFPEPT PYDDSHDNAT LSLDEWKRLC FREVKSFVPF PRRDSKRKNT 360

LTMS 364

Nucleotide Sequence
(FASTA)

TGTATCATGG AGGCACACGC ACATTTCTCT CGGGAGGAAA TAAACAACAC GGTGTGGGAA 60

GTCCCGGAGA AATATACACG GCTCAAACAG ATCGGTACCG GGGCGTACGG TTCCGTGTGC 120

TCAACAATAA ATGAGAAGAC TAAAGAGAAA GTGGCCATTA AGAAGCTCCA CAGGCCTTTC 180

CAGTCAGAGA TATTTGCGAA GAGGGCCTAC CGGGAGCTCC GGCTGCTCAA ACACATGAAG 240

CATGAGAATG TAATTGGACT TCTTGATGTG TTCACACCTG CCTTGGGACT CGATGAGATG 300

CAGGACTTCT ACCTTGTGAT GCCTTACATG TTCACTGACC TGTCAAAGGT GCGAGGCCCC 360

CTTTCTGAAG ACAAAGTCCA GTTTCTTATC TACCAGACGC TCTGTGGTCT CAGGTACATC 420

CACAAGGCTG GAATAATCCA CCGGGATCTT AAACCTGGAA ACTTGGCTGT AAATCAAGAC 480

TGTGAACTGA AGATTCTGGA CTTCGGCTTG GCCCGCAGTG CTGATGCTGA GATGACGGGC 540

TACGTGGTGA CCCGTTGGTA CCGGGCTCCC GAGGTCATTC TGAACTGGAT GCACTACACC 600

CAGACTGTGG ACATCTGGTC CGTGGGATGC ATCATGGCCG AAATGATCCA CGGAAAAACC 660

CTCTTCAAAG GGAAAGATTA CATGGACCAG CTGACTCAGA TCATGAAAGT GACAGGAGTT 720

CCTGGGCCAG AGTTCATACA GAAGCTGGAC AGCATTGAGG CCAAAAATTA TGTAAAGGCG 780

CTTCCTCGCT ATCCAAGGAA AGATTTTTCG ACGTTGTTCC CAAAGGCAAG TGCAAAGGGT 840

ATTGATCTGC TGGAAAAAAT GCTGGTTCTG GATGGAGACG AGAGGCTGAC AGCTGAACTT 900

GCTCTGGAGC ACTCCTATTT TGATAGCCTA AGAGATCCTG ACGACTTTCC TGAGCCTACG 960

CCATATGACG ACAGCCATGA CAACGCCACG TTATCCCTGG ATGAGTGGAA GCGATTATGT 1020

TTCAGAGAGG TGAAAAGCTT TGTGCCATTC CCACGGCGAG ACTCGAAGAG AAAAAACACC 1080

CTTACAATGT CT 1092

Domain Profile

S: 1     yeslkplgeGaygvvvsavdkrteervaikklsrpfqketsakrtlRElkllkelkheNi  60

         y+ lk++g+Gayg v+s+++++t+e+vaikkl rpfq+e+ akr++REl+llk++kheN+

Q: 25    YTRLKQIGTGAYGSVCSTINEKTKEKVAIKKLHRPFQSEIFAKRAYRELRLLKHMKHENV  84

         7889********************************************************

S: 61    iklldvftpeeeleelkdvYlvtelmetdLkkviksqklsdehiklllyqilrglkylHs  120

         i lldvftp+  l+e++d+Ylv+ +m tdL+kv  +  ls++++++l+yq l+gl+y+H

Q: 85    IGLLDVFTPALGLDEMQDFYLVMPYMFTDLSKV--RGPLSEDKVQFLIYQTLCGLRYIHK  142

         *******************************98..568**********************

S: 121   anviHrDlKPsNllvnedcelkildFGlarsadkekekklteyvatrwYraPeillslke  180

         a++iHrDlKP+Nl+vn+dcelkildFGlarsad+e    +t+yv+trwYraPe++l++++

Q: 143   AGIIHRDLKPGNLAVNQDCELKILDFGLARSADAE----MTGYVVTRWYRAPEVILNWMH  198

         ***********************************....*********************

S: 181   ytkavDiWsvGCIlaElltgkplfpgkdeidqlekilevlgtpseeflkkieseearnyi  240

         yt++vDiWsvGCI+aE+++gk+lf+gkd++dql++i++v+g p  ef++k+ s ea+ny+

Q: 199   YTQTVDIWSVGCIMAEMIHGKTLFKGKDYMDQLTQIMKVTGVPGPEFIQKLDSIEAKNYV  258

         ************************************************************

S: 241   kslpkkkkkdfeelfpkaseealdLleklLvldpdkRisveeaLehpYl  289

         k lp++++kdf++lfpkas + +dLlek+Lvld d+R+++e aLeh Y+

Q: 259   KALPRYPRKDFSTLFPKASAKGIDLLEKMLVLDGDERLTAELALEHSYF  307

         ***********************************************96

Domain Sequence
(FASTA)

YTRLKQIGTG AYGSVCSTIN EKTKEKVAIK KLHRPFQSEI FAKRAYRELR LLKHMKHENV 60

IGLLDVFTPA LGLDEMQDFY LVMPYMFTDL SKVRGPLSED KVQFLIYQTL CGLRYIHKAG 120

IIHRDLKPGN LAVNQDCELK ILDFGLARSA DAEMTGYVVT RWYRAPEVIL NWMHYTQTVD 180

IWSVGCIMAE MIHGKTLFKG KDYMDQLTQI MKVTGVPGPE FIQKLDSIEA KNYVKALPRY 240

PRKDFSTLFP KASAKGIDLL EKMLVLDGDE RLTAELALEH SYF 283

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004707	; F:MAP kinase activity
GO:0000165	; P:MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR003527	; MAP_kinase_CS.
IPR008352	; MAPK_p38.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS01351	; MAPK; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

PR01773

; P38MAPKINASE.

Created Date

20-Feb-2013