EKS-TAR-00314

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00314

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	330.6	1.3E-98	42	292	251

Status

Unreviewed

Ensembl Protein

ENSTRUP00000023292

UniProt Accession

H2TF48;

Protein Name

Protein Synonyms/Alias

Gene Name

NUAK2

Gene Synonyms/Alias

NUAK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000009262	ENSTRUP00000023292	ENSTRUT00000023389
ENSTRUG00000009262	ENSTRUP00000023291	ENSTRUT00000023388

Organism

Takifugu rubripes

Functional Description

Protein Length

569

Protein Sequence
(FASTA)

MGSRRSSSGG LFPGDCRAPA QAPVKKQAVK RHHHKHNLKH RYEFLETLGK GTYGKVKKAR 60

ERSARLVAIK SIRKEKIKDE QDLVHIRREI EIMSTLCHPH IITIYEVFEN KDKIVIVMEY 120

ASRGDLYDYI CDKRNISERE ARHFFRQIVS AVHYCHQNGI VHRDLKLENI LLDGSGNVKI 180

ADFGLSNLYH GDEYLQTFCG SPLYASPEIV NGRPYRGPEV DTWSLGVLLY TMVHGTMPFD 240

GQNHKTLVQQ ISTGNYRKPS NPSDACGLIR WMLMVNPERR ATIEEIAGHW WLNWGYQQPL 300

LAEPKPSPAD HSAPAAAPPP AQSAGLASVA NWLRRTSRPL LENGSKMRCL LRSQGGGGDV 360

VRQRSLRRSR KENNVSQTLV DLPAPADVPS ATALPRKGIL KKPTEESGYY SSSPENSDSG 420

LTAQPEECPS APTFRKGILK RNGKFSSGRL QEFGSLDQLA ASLPRPRPRP SGAISEDSIL 480

SSESFDQLDL PDRVGPPTQL EKPAKSSMRA CVSADNLLDI QEDGVLEDGL MRPWSCYKSG 540

VADSAFSITD CDNVTEAYKQ AMVLRGPAA 569

Nucleotide Sequence
(FASTA)

ATGGGAAGCC GTCGGTCGTC GTCGGGGGGA CTTTTCCCCG GTGATTGCAG AGCCCCGGCC 60

CAGGCTCCCG TGAAGAAGCA GGCGGTGAAG AGACACCACC ACAAACACAA CCTGAAGCAC 120

AGGTACGAGT TCCTGGAAAC CCTCGGGAAA GGAACCTACG GCAAAGTGAA GAAAGCCAGG 180

GAAAGGTCCG CCAGGCTGGT TGCCATAAAG TCGATCAGAA AGGAGAAGAT CAAGGATGAG 240

CAGGACTTGG TTCACATCCG CAGGGAGATC GAGATCATGT CCACGCTCTG CCACCCGCAC 300

ATCATCACCA TCTACGAAGT CTTTGAAAAT AAGGATAAAA TCGTAATCGT GATGGAGTAC 360

GCCAGCAGAG GGGACCTGTA CGACTACATC TGTGACAAGA GGAACATCTC TGAACGGGAG 420

GCCAGGCACT TCTTCAGGCA GATCGTGTCG GCCGTGCACT ACTGTCACCA GAATGGAATT 480

GTCCACCGGG ACCTGAAACT GGAGAATATT TTACTCGATG GCAGCGGGAA CGTGAAGATC 540

GCAGACTTCG GCCTGTCCAA CCTTTACCAT GGCGACGAGT ACCTGCAGAC CTTTTGCGGC 600

AGCCCTCTCT ACGCGTCCCC AGAGATCGTC AACGGGCGGC CGTACCGGGG GCCCGAGGTC 660

GACACGTGGT CTCTGGGTGT GCTGTTGTAC ACGATGGTTC ATGGCACCAT GCCGTTCGAC 720

GGACAGAACC ACAAGACCCT GGTGCAGCAG ATAAGCACAG GGAACTACAG GAAGCCCAGC 780

AACCCCTCTG ACGCGTGCGG GCTCATCCGG TGGATGCTGA TGGTAAATCC TGAGCGCAGA 840

GCCACAATAG AAGAGATTGC AGGGCACTGG TGGCTCAACT GGGGCTACCA GCAGCCGTTA 900

CTGGCCGAGC CCAAGCCCAG TCCGGCAGAC CACAGCGCCC CTGCGGCCGC CCCGCCCCCA 960

GCGCAGTCCG CCGGCCTGGC CAGTGTCGCC AACTGGCTCC GGCGCACGTC CAGGCCTTTG 1020

CTGGAGAACG GCTCCAAGAT GCGCTGCCTG CTGCGCTCCC AGGGGGGCGG GGGGGACGTT 1080

GTCCGGCAGC GGTCTCTGCG TCGGTCCCGG AAGGAGAACA ACGTCTCCCA GACTTTGGTG 1140

GATTTGCCGG CACCAGCCGA CGTTCCTTCT GCCACCGCGT TGCCTCGCAA AGGTATCCTA 1200

AAGAAGCCCA CAGAGGAGTC GGGGTACTAC TCCTCGTCTC CAGAGAACAG CGACTCTGGC 1260

CTGACGGCCC AACCAGAGGA GTGTCCTTCA GCGCCCACCT TCAGGAAGGG CATCTTGAAG 1320

CGCAACGGGA AGTTTTCTTC GGGCAGACTG CAGGAGTTCG GCTCCCTGGA TCAGCTGGCC 1380

GCGTCTCTGC CCCGCCCCAG GCCCAGGCCC AGCGGGGCCA TCAGCGAGGA CAGCATTCTG 1440

TCCTCCGAAT CCTTCGACCA GCTGGACCTC CCAGACCGTG TCGGACCTCC AACACAACTG 1500

GAAAAACCAG CCAAGTCGAG CATGAGAGCA TGCGTGTCCG CGGACAATCT TCTGGACATT 1560

CAGGAAGACG GGGTCCTGGA GGACGGGCTG ATGAGGCCCT GGAGCTGCTA CAAGTCCGGA 1620

GTGGCCGACA GCGCCTTCTC GATCACAGAC TGCGACAACG TGACCGAAGC CTACAAACAG 1680

GCCATGGTTC TCCGAGGCCC TGCAGCC 1707

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y++l+tlG+g++gkVk+a+++   + va+K i+k+k+ +e+ l +i+rEiei+++l hp+

Q: 42    YEFLETLGKGTYGKVKKARER-SARLVAIKSIRKEKIkDEQDLVHIRREIEIMSTLCHPH  100

         99****************998.5689*********996777899****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         ii ++ev+e+k+k+++v+eyas+g+L+dyi +k++++e+ear++f+q+vsav+Y+h++gi

Q: 101   IITIYEVFENKDKIVIVMEYASRGDLYDYICDKRNISEREARHFFRQIVSAVHYCHQNGI  160

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlK+eN+lld ++n+kiaDFGl+nl++ ++ l+tfcGsp Ya+Pe+++g++Y+gp+v

Q: 161   VHRDLKLENILLDGSGNVKIADFGLSNLYHGDEYLQTFCGSPLYASPEIVNGRPYRGPEV  220

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D WslGv+Ly++v g++Pfd++n k+l+++i++g+++ p++ s ++  L+r +L+v+pe+

Q: 221   DTWSLGVLLYTMVHGTMPFDGQNHKTLVQQISTGNYRKPSNPS-DACGLIRWMLMVNPER  279

         *****************************************66.5668************

S: 240   Ratieeilkhewl  252

         Ratieei  h wl

Q: 280   RATIEEIAGHWWL  292

         ************7

Domain Sequence
(FASTA)

YEFLETLGKG TYGKVKKARE RSARLVAIKS IRKEKIKDEQ DLVHIRREIE IMSTLCHPHI 60

ITIYEVFENK DKIVIVMEYA SRGDLYDYIC DKRNISEREA RHFFRQIVSA VHYCHQNGIV 120

HRDLKLENIL LDGSGNVKIA DFGLSNLYHG DEYLQTFCGS PLYASPEIVN GRPYRGPEVD 180

TWSLGVLLYT MVHGTMPFDG QNHKTLVQQI STGNYRKPSN PSDACGLIRW MLMVNPERRA 240

TIEEIAGHWW L 251

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013