EKS-TAR-00265

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00265

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	521.7	8.2E-157	4	287	284

Status

Unreviewed

Ensembl Protein

ENSTRUP00000024107

UniProt Accession

H2THF7;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL1

Gene Synonyms/Alias

CDKL1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000009594	ENSTRUP00000024108	ENSTRUT00000024207
ENSTRUG00000009594	ENSTRUP00000024107	ENSTRUT00000024206

Organism

Takifugu rubripes

Functional Description

Protein Length

353

Protein Sequence
(FASTA)

MEKYEKIGKI GEGSYGVVFK CRNRDTGQIV AIKKFVESED DPVIKKIALR EIRMLKQLKH 60

ANLVNLIEVF RRKRKLHLVF EYCDHTVLNE LDRHPRGVPE PLVRSITWQT LQAVNFCHKQ 120

SCIHRDVKPE NILITKQQVI KLCDFGFARI LTGPSDYYTD YVATRWYRAP ELLVGDTQYG 180

PPVDVWAIGC VFAELLSGIP LWPGKSDMDQ LYLIRKTLGD LIPRHQQVFS NNQFFCGVSI 240

PEPQEMDPLE QKYPNVSVQA LSLMKGCLRM DPSERLTCEQ LLLHPYFDSL REKSESSSRE 300

QDRSRRTRFP RKHHPPGVNS QYLPQLTSSS IFPAVDNKRY YNLRKFNYHL PNI 353

Nucleotide Sequence
(FASTA)

ATGGAGAAGT ACGAGAAGAT TGGGAAGATC GGCGAGGGCT CCTACGGTGT TGTGTTCAAG 60

TGCAGGAACA GAGACACGGG CCAGATCGTC GCCATCAAGA AGTTCGTGGA GTCCGAAGAC 120

GATCCCGTCA TCAAAAAGAT CGCGCTGAGG GAGATCCGGA TGCTGAAGCA ACTGAAACAC 180

GCCAACCTGG TGAATCTGAT CGAGGTGTTC CGCCGCAAAC GGAAGCTTCA CCTGGTGTTC 240

GAGTACTGCG ACCACACGGT CCTCAACGAG CTGGACCGCC ATCCCAGAGG GGTTCCAGAG 300

CCGCTGGTCA GGAGTATAAC CTGGCAGACT CTTCAAGCTG TCAACTTCTG TCACAAACAG 360

AGTTGCATCC ATCGAGACGT CAAACCTGAA AACATTCTCA TCACCAAACA GCAGGTCATC 420

AAACTCTGCG ATTTCGGCTT TGCCAGGATT CTCACTGGAC CATCTGACTA TTACACGGAC 480

TATGTGGCGA CCCGCTGGTA TCGGGCCCCC GAGCTGCTGG TGGGGGACAC TCAGTACGGT 540

CCTCCGGTGG ACGTGTGGGC CATCGGCTGT GTGTTCGCAG AGCTGCTGTC AGGGATCCCA 600

CTGTGGCCCG GGAAGTCGGA CATGGACCAG CTGTACCTGA TCAGAAAGAC TCTGGGAGAT 660

CTGATCCCTC GGCATCAGCA GGTCTTCAGC AACAACCAGT TCTTCTGTGG CGTCTCAATC 720

CCAGAACCAC AGGAGATGGA CCCTCTGGAG CAGAAATATC CAAATGTCTC AGTCCAGGCT 780

CTGAGTCTCA TGAAGGGTTG TCTGAGGATG GACCCGTCAG AGCGGCTGAC CTGCGAGCAG 840

CTGTTGCTGC ACCCGTACTT CGACAGCCTG AGGGAAAAGA GCGAGAGCAG CTCTCGGGAG 900

CAGGACCGCA GCAGGAGGAC GCGCTTCCCT CGGAAACACC ATCCTCCCGG GGTAAATTCC 960

CAGTATCTCC CCCAGCTGAC CAGCAGCAGC ATCTTCCCCG CTGTGGACAA CAAGAGGTAC 1020

TACAACCTGC GGAAGTTCAA CTACCACCTC CCCAACATCT AA 1062

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yek+gk+GeGsyGvv+kcrn+dtgqivaikkf+esedd+++kkialrei++lkqlkh nl

Q: 4     YEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFVESEDDPVIKKIALREIRMLKQLKHANL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfrrk+kl+lvfey+d+tvl+el+r+p+Gv+e lv++i++q+l+a++fchk+ +i

Q: 64    VNLIEVFRRKRKLHLVFEYCDHTVLNELDRHPRGVPEPLVRSITWQTLQAVNFCHKQSCI  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili+k++v+klcdfGfar+l++p+d+ytdyvatrwyrapellvgdt+yG++v

Q: 124   HRDVKPENILITKQQVIKLCDFGFARILTGPSDYYTDYVATRWYRAPELLVGDTQYGPPV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGc++aell+G pl+pgksd+dqly+irktlG+liprhq++fs+n++f Gv++pe+

Q: 184   DVWAIGCVFAELLSGIPLWPGKSDMDQLYLIRKTLGDLIPRHQQVFSNNQFFCGVSIPEP  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++++le+kyp+++  +l+l+k+cl++dp+erl+ce+ll h+yf

Q: 244   QEMDPLEQKYPNVSVQALSLMKGCLRMDPSERLTCEQLLLHPYF  287

         *******************************************9

Domain Sequence
(FASTA)

YEKIGKIGEG SYGVVFKCRN RDTGQIVAIK KFVESEDDPV IKKIALREIR MLKQLKHANL 60

VNLIEVFRRK RKLHLVFEYC DHTVLNELDR HPRGVPEPLV RSITWQTLQA VNFCHKQSCI 120

HRDVKPENIL ITKQQVIKLC DFGFARILTG PSDYYTDYVA TRWYRAPELL VGDTQYGPPV 180

DVWAIGCVFA ELLSGIPLWP GKSDMDQLYL IRKTLGDLIP RHQQVFSNNQ FFCGVSIPEP 240

QEMDPLEQKY PNVSVQALSL MKGCLRMDPS ERLTCEQLLL HPYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013