EKS-TAR-00426

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00426

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	319.7	3.4E-95	319	565	247

Status

Unreviewed

Ensembl Protein

ENSTRUP00000024555

UniProt Accession

H2TIP9;

Protein Name

Protein Synonyms/Alias

Gene Name

PAK7

Gene Synonyms/Alias

PAK7;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000009772	ENSTRUP00000024555	ENSTRUT00000024654
ENSTRUG00000009772	ENSTRUP00000024552	ENSTRUT00000024651
ENSTRUG00000009772	ENSTRUP00000024551	ENSTRUT00000024650
ENSTRUG00000009772	ENSTRUP00000024554	ENSTRUT00000024653
ENSTRUG00000009772	ENSTRUP00000024553	ENSTRUT00000024652

Organism

Takifugu rubripes

Functional Description

Protein Length

584

Protein Sequence
(FASTA)

MFGKKKKRLE ISAPSNFEHR VHTGFDPREQ KFTGLPQQWQ SLLADTANRP KPMVDPSYIT 60

PIQLAPMKTI VRGNRPPKDA SINGLLEEFD NISVTRSNSL RKESPPGPHQ AGMETGRFQD 120

YRDTSVGTPS RASLHSEQIN YPDSEWSYGG LRDEYEKRPK SSYVTQTSPT PAIRQRSRSG 180

SGLQEPHIPY AASGAWCLDE KPFNLHAQPA VPANDRGARG WAVPAAPPPP LHLPESDITN 240

LRPTTTSRPS PVHLTPPRYS MLVYPHPSSP YIPPGAYPPP SWGSSSDTQP SRVSHEQFRA 300

ALQLVVNPGD PREYLDSFIK IGEGSTGIVC IASEKHSGKQ VAVKKMDLRK QQRRELLFNE 360

VVIMRDYHHE NVVDMYNSYL VGDELWVVME FLEGGALTDI VTHTRMNEEQ IATVCLSVLK 420

ALSYLHMQGV IHRDKSDSIL LTSDGRIKLS DFGFCAQVSK EVPKRKSLVG TPYWMAPEVI 480

SRLPYGTEVD IWSLGIMVIE MVDGEPPYFN EPPLQAMRRI RDNLPPRLKE SHKVSSVLRS 540

FLDRMLVREP SQRATAQDLL QHPFLKMSGP PSCIVPLMRH YRHR 584

Nucleotide Sequence
(FASTA)

ATGTTTGGGA AGAAGAAGAA ACGGCTGGAG ATCTCGGCCC CGTCTAACTT TGAGCACCGC 60

GTCCACACGG GCTTCGACCC GCGGGAGCAG AAGTTCACCG GGCTGCCTCA GCAATGGCAG 120

AGCCTGCTGG CGGACACTGC CAACCGGCCC AAGCCTATGG TTGACCCCTC CTACATCACC 180

CCCATTCAGC TGGCGCCCAT GAAGACTATC GTTCGAGGGA ACCGGCCACC CAAAGATGCA 240

TCCATCAATG GCCTTCTGGA GGAGTTTGAC AACATCTCCG TGACCCGCTC CAATTCTCTG 300

CGTAAGGAAA GTCCGCCCGG CCCCCATCAG GCAGGAATGG AGACTGGGCG ATTTCAGGAT 360

TACAGGGACA CTTCGGTAGG AACTCCATCT CGTGCTTCCC TACACAGCGA GCAGATCAAC 420

TATCCAGACA GCGAGTGGAG CTATGGTGGC CTTCGGGACG AGTACGAAAA ACGACCCAAG 480

AGTTCGTACG TGACGCAGAC GAGCCCCACG CCGGCAATAA GGCAGCGCTC CCGCTCGGGC 540

TCTGGGTTGC AGGAGCCACA CATTCCCTAT GCAGCCAGTG GAGCTTGGTG CCTTGATGAA 600

AAACCATTTA ACCTGCACGC CCAGCCAGCG GTGCCGGCCA ACGATAGGGG GGCTCGGGGC 660

TGGGCTGTCC CGGCAGCACC CCCCCCCCCC CTCCACCTGC CGGAGAGTGA CATTACAAAC 720

CTTCGCCCTA CCACCACCTC CCGTCCCAGC CCAGTCCACC TTACACCCCC CAGGTACAGT 780

ATGCTAGTTT ACCCTCATCC TTCATCACCT TACATCCCTC CGGGGGCCTA CCCACCTCCA 840

TCCTGGGGGT CCAGCTCTGA CACTCAGCCT TCTAGAGTCT CTCACGAGCA GTTCAGAGCT 900

GCACTTCAGC TGGTGGTCAA CCCAGGGGAC CCCCGGGAAT ACCTGGACAG TTTCATCAAA 960

ATCGGTGAAG GCTCCACGGG GATCGTGTGC ATCGCCAGCG AGAAACATAG CGGCAAACAG 1020

GTGGCCGTGA AGAAAATGGA CCTGAGGAAG CAGCAGAGAA GGGAGCTGCT CTTCAACGAG 1080

GTGGTGATCA TGAGGGACTA CCATCATGAA AATGTGGTCG ACATGTACAA CAGCTACCTA 1140

GTGGGAGACG AGCTGTGGGT TGTCATGGAG TTCCTGGAGG GGGGGGCTCT CACAGACATT 1200

GTGACCCACA CCAGGATGAA CGAGGAGCAG ATCGCCACTG TGTGTTTGTC GGTGCTCAAG 1260

GCTCTGTCCT ACCTGCATAT GCAGGGCGTC ATACACAGGG ACAAGAGCGA CTCCATTCTC 1320

CTGACTAGTG ATGGCAGGAT AAAGCTGTCA GACTTTGGCT TTTGTGCCCA AGTTTCCAAA 1380

GAGGTGCCCA AGAGGAAATC CCTTGTGGGC ACACCCTACT GGATGGCTCC GGAGGTCATT 1440

TCCAGGCTAC CATACGGCAC AGAGGTGGAT ATCTGGTCTC TGGGCATCAT GGTGATCGAG 1500

ATGGTGGATG GAGAGCCCCC TTACTTTAAT GAGCCCCCTT TACAGGCCAT GAGGCGGATA 1560

CGAGACAACC TGCCCCCCAG GTTAAAAGAG TCTCACAAGG TCTCCTCTGT CTTGCGATCT 1620

TTCCTGGACC GGATGCTTGT GCGGGAACCC TCACAGAGAG CCACCGCCCA GGATCTCCTC 1680

CAGCACCCGT TCCTCAAGAT GTCTGGACCG CCCTCCTGTA TCGTCCCCCT CATGAGACAC 1740

TATCGCCACC GTTGA 1755

Domain Profile

S: 5     eeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkhpniveyles  64

          +ig+G++g v++a ek++g++va+kk++l+kq++ e+l++e+ ++++++h+n+v++++s

Q: 319   IKIGEGSTGIVCIASEKHSGKQVAVKKMDLRKQQRRELLFNEVVIMRDYHHENVVDMYNS  378

         68**********************************************************

S: 65    flkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkviHrdi  124

         +l+ +elw+vme+l+gG+l+d+v+   +++++Eeqia+++ +vlkaL+ylH ++viHrd

Q: 379   YLVGDELWVVMEFLEGGALTDIVT---HTRMNEEQIATVCLSVLKALSYLHMQGVIHRD-  434

         ************************...9*******************************.

S: 125   kakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYdekaDiw  184

         k+++iLlt++g++kLsdfg++aq++k++ krk++vgtpywmAPEvi+  +  Y +++Diw

Q: 435   KSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVIS--RLPYGTEVDIW  492

         ***********************************************..9**********

S: 185   slGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclqknpek  244

         slGI++ie+++gepP+++++pl+a+ +i +n pp+lk+++k+s+ +++f++++l ++p++

Q: 493   SLGIMVIEMVDGEPPYFNEPPLQAMRRIRDNLPPRLKESHKVSSVLRSFLDRMLVREPSQ  552

         ************************************************************

S: 245   RpsasellkhkFl  257

         R++a++ll+h+Fl

Q: 553   RATAQDLLQHPFL  565

         ************7

Domain Sequence
(FASTA)

IKIGEGSTGI VCIASEKHSG KQVAVKKMDL RKQQRRELLF NEVVIMRDYH HENVVDMYNS 60

YLVGDELWVV MEFLEGGALT DIVTHTRMNE EQIATVCLSV LKALSYLHMQ GVIHRDKSDS 120

ILLTSDGRIK LSDFGFCAQV SKEVPKRKSL VGTPYWMAPE VISRLPYGTE VDIWSLGIMV 180

IEMVDGEPPY FNEPPLQAMR RIRDNLPPRL KESHKVSSVL RSFLDRMLVR EPSQRATAQD 240

LLQHPFL 247

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000095	; PAK_box_Rho-bd.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF00786	; PBD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00285	; PBD; 1.
SM00220	; S_TKc; 1.

Prosites

PS50108	; CRIB; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013