EKS-TAR-00329

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00329

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	245.6	1.1E-72	47	308	262

Status

Unreviewed

Ensembl Protein

ENSTRUP00000024843

UniProt Accession

H2TJI9;

Protein Name

Protein Synonyms/Alias

Gene Name

STK11

Gene Synonyms/Alias

STK11;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000009891	ENSTRUP00000024842	ENSTRUT00000024943
ENSTRUG00000009891	ENSTRUP00000024843	ENSTRUT00000024944

Organism

Takifugu rubripes

Functional Description

Protein Length

439

Protein Sequence
(FASTA)

MSAAELHHLD YLNENELMEM DTFIHRIDST EVIYQPRRKR AKLIGKYLMG DLLGEGSYGK 60

VKEMLDSETL CRRAVKILKK KKLRRIPNGE ANVKKEIQLL RRLQHKNVIQ LVDVLYNEEK 120

QKLTYMVMEY CVCGMQEMLD SVPEKRFPVF QAHGYFCQLL DGLEYLHSQG IVHKDIKPGN 180

LLLTTDGALK ISDLGVAEAL HPFAEDDTCR TSQGSPAFQP PEIANGLDTF SGFKVDIWSA 240

GVTLYNITTS LYPFEGDNIY KLFENIGKGD YTVPEECGPL LSDLLRGMLE YDPAKRFSIQ 300

KIRQHSWVRK KHPPSESPVP IPASAECRDP WRSMTVVPYL EDLHGYAEED DDELYDGEDE 360

IIYTQDFTVP GQVADDNLDE GSADHSPALA KPVCVNGTEA ASLNSKAKAE RRSSSSSNPS 420

RKGVSTASKI RKLSTCKQQ 439

Nucleotide Sequence
(FASTA)

ATGAGCGCCG CCGAGCTGCA TCACCTCGAC TACCTGAACG AGAACGAGCT GATGGAGATG 60

GACACGTTCA TCCACCGCAT CGACTCCACG GAGGTGATCT ACCAGCCCAG GAGGAAGCGG 120

GCGAAGCTGA TCGGGAAGTA TCTGATGGGA GACCTCCTCG GGGAGGGGTC GTACGGCAAA 180

GTGAAGGAGA TGCTGGACTC GGAGACGCTT TGCCGCAGGG CCGTTAAGAT CCTGAAGAAG 240

AAGAAGTTGA GGAGGATTCC TAACGGAGAA GCTAATGTGA AAAAGGAAAT ACAGCTGCTA 300

AGGAGACTCC AACACAAGAA CGTGATCCAG TTGGTTGACG TTCTCTACAA CGAAGAGAAG 360

CAGAAACTCA CGTATATGGT GATGGAGTAT TGCGTTTGTG GGATGCAAGA AATGTTGGAC 420

AGCGTCCCAG AGAAAAGGTT TCCAGTATTT CAAGCTCACG GGTACTTTTG CCAACTTTTA 480

GATGGCCTTG AATATTTGCA CAGCCAGGGA ATCGTTCACA AAGACATTAA ACCAGGAAAT 540

CTGCTGCTGA CCACAGACGG GGCGCTCAAA ATCTCTGACC TGGGAGTCGC GGAGGCCCTT 600

CATCCTTTTG CGGAGGACGA CACCTGTCGA ACCAGTCAGG GCTCCCCGGC CTTCCAGCCA 660

CCAGAGATCG CCAACGGACT GGACACCTTT TCAGGGTTTA AAGTGGACAT TTGGTCCGCT 720

GGAGTAACAC TATACAACAT TACAACAAGT CTGTATCCAT TCGAGGGGGA CAACATCTAT 780

AAGCTATTTG AGAACATTGG AAAAGGAGAT TACACTGTTC CAGAAGAATG TGGACCTCTC 840

CTGTCGGACC TGCTGCGAGG AATGCTCGAG TACGACCCTG CAAAAAGGTT CTCCATACAG 900

AAAATAAGGC AACACAGCTG GGTGCGTAAG AAACACCCTC CGTCCGAGTC CCCCGTGCCC 960

ATCCCTGCCA GCGCAGAGTG CAGGGACCCG TGGCGGAGCA TGACGGTGGT GCCCTACCTG 1020

GAGGACCTGC ACGGCTACGC GGAGGAGGAC GATGACGAGC TCTACGACGG AGAAGACGAG 1080

ATCATATACA CTCAGGACTT CACAGTGCCA GGACAAGTGG CGGATGATAA TCTGGATGAG 1140

GGAAGCGCGG ACCACAGCCC AGCTCTGGCC AAGCCAGTGT GTGTCAACGG GACAGAGGCG 1200

GCGTCTCTGA ACAGCAAAGC CAAAGCTGAA CGCCGGTCCT CCTCTTCATC CAACCCTTCA 1260

CGCAAAGGAG TTTCTACAGC CAGCAAGATC CGCAAGCTCT CTACATGCAA ACAGCAGTGA 1320

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl..seeslekikrEieilkklkhp  58

         y +++ lGegs+gkVk++ ++et  + avKi+kkkkl    +   ++k+Ei++l++l+h+

Q: 47    YLMGDLLGEGSYGKVKEMLDSETLCRRAVKILKKKKLrrIPNGEANVKKEIQLLRRLQHK  106

         778999******************************965334567***************

S: 59    niikllevi...etkkklylvleyasgg..eLfdyieekgrlkekearklfkqlvsavkY  113

         n+i+l++v+   e++k +y+v+ey+  g  e++d +  ++r++  +a+ +f ql+++++Y

Q: 107   NVIQLVDVLyneEKQKLTYMVMEYCVCGmqEMLDSV-PEKRFPVFQAHGYFCQLLDGLEY  165

         ********9775666778******998888*****6.8899*******************

S: 114   lhskgivHrDlKpeNllldkkenikiaDFGlan...lfkegklletfcGsppYaaPellk  170

         lhs+givH+D+Kp Nlll++++ +ki+D+G+a+    f e+++++t++Gsp++++Pe+ +

Q: 166   LHSQGIVHKDIKPGNLLLTTDGALKISDLGVAEalhPFAEDDTCRTSQGSPAFQPPEIAN  225

         ********************************966567788******************9

S: 171   g.kkYegpkvDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLl  229

         g ++++g kvD+Ws+Gv+Ly++ t  +Pf+++n+ +l+e+i kg++++p+++ + l++Ll

Q: 226   GlDTFSGFKVDIWSAGVTLYNITTSLYPFEGDNIYKLFENIGKGDYTVPEECGPLLSDLL  285

         9899********************************************************

S: 230   rklLvvdpekRatieeilkhewl  252

         r +L+ dp+kR++i++i++h+w+

Q: 286   RGMLEYDPAKRFSIQKIRQHSWV  308

         **********************7

Domain Sequence
(FASTA)

YLMGDLLGEG SYGKVKEMLD SETLCRRAVK ILKKKKLRRI PNGEANVKKE IQLLRRLQHK 60

NVIQLVDVLY NEEKQKLTYM VMEYCVCGMQ EMLDSVPEKR FPVFQAHGYF CQLLDGLEYL 120

HSQGIVHKDI KPGNLLLTTD GALKISDLGV AEALHPFAED DTCRTSQGSP AFQPPEIANG 180

LDTFSGFKVD IWSAGVTLYN ITTSLYPFEG DNIYKLFENI GKGDYTVPEE CGPLLSDLLR 240

GMLEYDPAKR FSIQKIRQHS WV 262

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013