EKS-TAR-00363

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00363

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	424.9	3.4E-127	225	514	290

Status

Unreviewed

Ensembl Protein

ENSTRUP00000027828

UniProt Accession

H2TT18;

Protein Name

Protein Synonyms/Alias

Gene Name

BMPR1A

Gene Synonyms/Alias

BMPR1A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000011026	ENSTRUP00000027825	ENSTRUT00000027935
ENSTRUG00000011026	ENSTRUP00000027827	ENSTRUT00000027937
ENSTRUG00000011026	ENSTRUP00000027826	ENSTRUT00000027936
ENSTRUG00000011026	ENSTRUP00000027828	ENSTRUT00000027938

Organism

Takifugu rubripes

Functional Description

Protein Length

525

Protein Sequence
(FASTA)

STQLSTHVKF CQYCWVSVHP AAGQNPDYVL QGTGVKPEDS TIAPEDTARF LSCYCSGHCP 60

EDATNNTCQT NGQCFAIIQE DEHGEALLTS GCMKYEGSHF QCKDSPKAQT RRTIECCNTD 120

FCNRDLQPTL PPLAPTVLEG SPHWLAFLIS MTVCCCMLIC VTVVCYYRYK WQSERQQYHK 180

NRKDLEQEVF IPAGESLKDL IHQSQSSGSG SGLPLLVQRT IAKQIQMMRQ IGKGRYGEVW 240

LGRWRGEKVA VKVFFTREEA SWFRETEIYQ TVLMRHDNIL GFIAADIKGT GAFTQLFLIT 300

DYHENGSLYD YLKLTTLDTQ MLLRLAYSAA CGLCHLHTEI YGTQGKPAIA HRDLKSKNIL 360

IKKNGTCCIA DLGLAVKFNS HSDTNEVDIP LSTRVGTRRY MAPEVLNESL NKNHFQAYIM 420

ADIYSYGLII WEMGRRCVTG GMVEDYQLPY YDMVPSDPSY EDMLEVVCVK GLRPTVSNRW 480

NSNECLRAML KLMSECWALN PASRLTILRV KKTLAKMVES QDIKV 525

Nucleotide Sequence
(FASTA)

TCCACACAAT TAAGCACACA TGTAAAATTT TGTCAGTATT GCTGGGTGTC TGTTCACCCA 60

GCTGCTGGTC AGAACCCTGA CTATGTCCTG CAAGGGACAG GGGTCAAACC CGAGGACTCC 120

ACCATCGCCC CAGAGGATAC CGCCCGATTT CTGAGCTGCT ACTGCTCTGG ACACTGTCCT 180

GAAGATGCCA CCAACAACAC CTGCCAAACC AACGGTCAGT GCTTCGCCAT CATCCAGGAA 240

GACGAACACG GGGAGGCCCT GCTGACATCG GGCTGCATGA AGTATGAAGG CTCGCACTTC 300

CAGTGTAAGG ACTCTCCCAA AGCTCAGACC AGAAGGACCA TCGAGTGCTG CAACACTGAC 360

TTCTGTAACA GAGACCTGCA GCCCACACTA CCCCCGCTGG CCCCCACTGT TTTAGAGGGT 420

AGTCCTCATT GGCTGGCCTT CCTTATCTCC ATGACGGTCT GCTGCTGCAT GCTGATCTGT 480

GTCACTGTGG TCTGTTACTA CAGGTATAAG TGGCAAAGTG AGCGACAGCA GTATCACAAG 540

AATCGCAAGG ATCTGGAACA GGAAGTCTTT ATTCCTGCTG GGGAGTCACT CAAGGATCTC 600

ATCCACCAAT CACAGAGCTC CGGCAGTGGC TCGGGACTCC CTCTGCTGGT GCAGCGAACC 660

ATCGCCAAGC AGATCCAGAT GATGCGTCAG ATTGGTAAGG GGCGTTATGG CGAGGTGTGG 720

CTTGGCCGCT GGCGAGGCGA GAAGGTAGCT GTCAAGGTGT TCTTCACACG AGAAGAGGCC 780

AGCTGGTTCA GAGAGACGGA GATTTACCAA ACAGTCCTGA TGAGACATGA TAACATTCTC 840

GGCTTCATTG CAGCTGACAT TAAGGGCACG GGTGCGTTCA CACAACTCTT CCTCATCACT 900

GATTACCACG AGAACGGCTC GCTGTACGAC TACCTGAAGC TGACCACGCT GGATACGCAG 960

ATGCTGCTGC GGCTGGCGTA CTCGGCAGCG TGTGGCCTCT GTCACCTTCA CACTGAAATC 1020

TATGGCACAC AAGGTAAACC TGCCATCGCC CACCGAGACC TGAAGAGCAA GAACATCCTG 1080

ATCAAGAAGA ATGGAACGTG TTGCATTGCT GACCTCGGCC TCGCCGTCAA GTTCAACAGC 1140

CATAGCGACA CAAATGAAGT GGACATCCCT CTGAGCACCC GTGTTGGGAC ACGGCGCTAC 1200

ATGGCCCCCG AGGTCCTGAA CGAGAGCCTG AACAAAAATC ACTTCCAGGC GTACATCATG 1260

GCCGATATCT ACAGCTACGG ACTCATCATC TGGGAGATGG GCAGACGTTG TGTGACAGGA 1320

GGGATGGTGG AGGACTACCA GCTGCCATAC TACGACATGG TTCCATCGGA TCCATCCTAT 1380

GAAGACATGC TGGAGGTGGT CTGTGTCAAA GGCCTGAGGC CCACCGTCTC CAACCGCTGG 1440

AACAGTAACG AGTGTCTTCG TGCCATGCTG AAGCTGATGT CAGAGTGTTG GGCCCTTAAC 1500

CCCGCCTCCC GCCTCACCAT CCTCCGAGTG AAGAAGACCC TGGCCAAGAT GGTGGAGTCA 1560

CAGGACATCA AAGTCTGA 1578

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         ++++++igkGrygeVw +++rge+vAvK+f+t++easw+rE+eiyqtvl+rh+nil+fia

Q: 225   IQMMRQIGKGRYGEVWLGRWRGEKVAVKVFFTREEASWFRETEIYQTVLMRHDNILGFIA  284

         799*********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k ++  t+l+l+t+yhe+gsL+dyLk +tld++ llrla+s+a+Gl+hLH+ei gt+

Q: 285   ADIKGTGAFTQLFLITDYHENGSLYDYLKLTTLDTQMLLRLAYSAACGLCHLHTEIYGTQ  344

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekee..ldlaansqvGtkRYma  178

         g  KpaiaHRDlkskNil+kk++tcciaDlGLa+k+++++++  +d+  +++vGt+RYma

Q: 345   G--KPAIAHRDLKSKNILIKKNGTCCIADLGLAVKFNSHSDTneVDIPLSTRVGTRRYMA  402

         *..*******************************99876544339999************

S: 179   PEvleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsle  238

         PEvl+e+ln ++f+a+ +aD+Ys gL++WE+ +Rc + +++ve+y+lp++++v+sdPs+e

Q: 403   PEVLNESLNKNHFQAYIMADIYSYGLIIWEMGRRCVT-GGMVEDYQLPYYDMVPSDPSYE  461

         *************************************.**********************

S: 239   emkevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         +m evv++k lrP+++++w+++e+l+++ kl++ecW+ +p++Rlt lrvkk+l

Q: 462   DMLEVVCVKGLRPTVSNRWNSNECLRAMLKLMSECWALNPASRLTILRVKKTL  514

         ***************************************************97

Domain Sequence
(FASTA)

IQMMRQIGKG RYGEVWLGRW RGEKVAVKVF FTREEASWFR ETEIYQTVLM RHDNILGFIA 60

ADIKGTGAFT QLFLITDYHE NGSLYDYLKL TTLDTQMLLR LAYSAACGLC HLHTEIYGTQ 120

GKPAIAHRDL KSKNILIKKN GTCCIADLGL AVKFNSHSDT NEVDIPLSTR VGTRRYMAPE 180

VLNESLNKNH FQAYIMADIY SYGLIIWEMG RRCVTGGMVE DYQLPYYDMV PSDPSYEDML 240

EVVCVKGLRP TVSNRWNSNE CLRAMLKLMS ECWALNPASR LTILRVKKTL 290

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013