EKS-TAR-00377

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00377

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	401.5	4.0E-120	528	788	261

Status

Unreviewed

Ensembl Protein

ENSTRUP00000028502

UniProt Accession

H2TUZ6;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN2

Gene Synonyms/Alias

ERN2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000011288	ENSTRUP00000028502	ENSTRUT00000028616
ENSTRUG00000011288	ENSTRUP00000028503	ENSTRUT00000028617
ENSTRUG00000011288	ENSTRUP00000028500	ENSTRUT00000028614
ENSTRUG00000011288	ENSTRUP00000028501	ENSTRUT00000028615
ENSTRUG00000011288	ENSTRUP00000028505	ENSTRUT00000028619
ENSTRUG00000011288	ENSTRUP00000028504	ENSTRUT00000028618

Organism

Takifugu rubripes

Functional Description

Protein Length

917

Protein Sequence
(FASTA)

MGRDSRAIEY LGRLLLSVFL LSWEGKLVQV GGVRSVTLPE SLLFVSTLDG SLHAVSKQTG 60

DIKWTLREDP IIQVPVYVTE PGFLPDPNDG SLYVLGGKHM EGLMKLPFTI PELVQSAPCR 120

SSDGILYTGN NQGKKHDVWF VVDPETGEKQ TSLTTSSSES ICPNTPLLYI GRTEYMVTMF 180

DTKTQELRWN ATYNDYSAPP YDEKQDYKMA HLVSSGDGLV VTVDRESGDV LWSQNYGSPV 240

VGVYLYSGDT LRHAPHVSLA LETLRFLTFS ANNLADARST LKWSYQFVKE QASAQAQLVP 300

TLYVGKLDSH LYASTSLVHH GVSLVPRGLT LARIEGPLTA EVTLRERGAC EITPSTDIRY 360

PAGSTSSQKN HWLLIGHHEL PPVAHTTMLR DFPSSLQRSA EAVIPPRPSA SPASDYHQLY 420

VSHGYTCHPG NLNSQSLKTM LKLKCLSCAF SSTKVAALVA MPMLTEEQLM SRRGREPDWP 480

HHKDSKLCPW SLLTQRLLQT PTFPAIHHVF LPPSEGNGRE VPVGKISFTP SEVLGHGSAG 540

TFVFRGNFDG RDVAVKRILP ECVEVAEREV QLLRASDTHP NVIRYFCTER DRLFTYIAIE 600

LCAATLQQYV EDPARFPELS PVSLLEQTMC GLSHLHSLNI VHRDLKPRNI LLSAPNALGQ 660

VRALISDFGL CKKIPDGRSS FSLRSGIPGT EGWIAPEVLR DTPGNKTTAA VDVFSAGCVF 720

YFVISRGQHP FGDTLRRQVN ILAGEYSLLH FKQGLHEDII AQNLIEQMIA AAAETRPSCS 780

CVLKHPFFWS PERQLLFFQD VSDRIEKEPA DSPIVLTLEN GGRAVVRTNW RMHISVPLQI 840

DLRRFRTYKG NSVRDLLRAM RNKKHHYHEL PSEVQETLGE LPDGFINYFT SRFPRLLMHT 900

YEALHICSHE RLFHPYY 917

Nucleotide Sequence
(FASTA)

ATGGGAAGAG ATTCGAGGGC CATAGAATAC CTGGGGCGTC TGCTGCTGTC CGTTTTCCTG 60

CTCTCATGGG AGGGAAAACT GGTTCAGGTT GGAGGGGTCA GATCAGTGAC CCTGCCTGAG 120

TCACTGCTAT TTGTGTCAAC ACTGGATGGA AGTCTGCATG CTGTCTCCAA ACAGACAGGA 180

GACATCAAAT GGACCCTCAG AGAAGACCCT ATAATTCAAG TACCGGTTTA TGTCACAGAG 240

CCAGGCTTCC TTCCAGACCC CAACGATGGC AGCTTGTATG TCCTGGGTGG CAAGCATATG 300

GAGGGGCTTA TGAAACTGCC ATTCACCATC CCAGAGCTGG TGCAGTCAGC TCCCTGCAGG 360

AGCTCTGATG GTATACTGTA TACAGGTAAC AATCAAGGTA AAAAACATGA TGTTTGGTTT 420

GTGGTGGATC CTGAGACTGG TGAAAAGCAA ACCAGTTTAA CCACTTCTTC ATCTGAATCT 480

ATCTGCCCCA ATACTCCCCT GCTGTACATT GGACGCACAG AATATATGGT CACAATGTTT 540

GACACTAAGA CACAGGAGCT GCGCTGGAAT GCTACATACA ATGACTACTC TGCTCCCCCG 600

TATGATGAGA AACAAGACTA CAAGATGGCT CATCTTGTGT CCAGTGGCGA CGGCCTCGTA 660

GTGACGGTTG ATAGAGAGTC AGGCGATGTC TTGTGGAGTC AGAACTATGG CTCGCCCGTT 720

GTGGGGGTGT ACCTCTATTC TGGGGACACA CTCAGACACG CGCCCCACGT CTCCCTCGCC 780

CTGGAAACGT TACGCTTCCT CACCTTTTCA GCCAACAACC TGGCAGACGC ACGCTCAACG 840

CTGAAATGGA GCTACCAGTT TGTGAAGGAG CAAGCCAGCG CACAAGCACA ACTTGTGCCC 900

ACTCTCTATG TAGGGAAGTT AGACTCCCAC CTTTATGCCT CCACCTCTCT CGTCCACCAC 960

GGGGTCTCAT TAGTGCCCCG AGGATTGACG CTTGCTCGGA TTGAGGGCCC TCTGACGGCT 1020

GAAGTGACCC TCAGAGAGCG AGGGGCATGT GAGATTACAC CGTCCACTGA TATTCGCTAT 1080

CCAGCCGGGA GCACAAGCAG CCAGAAAAAT CACTGGCTGC TCATAGGTCA TCATGAGCTC 1140

CCTCCAGTTG CTCACACCAC CATGTTGAGG GATTTTCCAA GTAGTCTGCA GCGTTCTGCT 1200

GAGGCGGTCA TCCCTCCGAG ACCCTCGGCC TCGCCTGCAT CAGACTACCA CCAGCTTTAT 1260

GTGAGTCACG GCTACACGTG TCACCCTGGC AACTTAAACA GTCAAAGCCT AAAGACAATG 1320

CTTAAGCTAA AATGCCTCTC TTGTGCGTTT AGCTCCACAA AAGTGGCGGC GCTCGTAGCG 1380

ATGCCAATGC TAACAGAGGA GCAGTTAATG AGCAGACGGG GCAGAGAGCC AGATTGGCCA 1440

CATCATAAAG ATAGTAAGCT GTGCCCTTGG TCCCTTCTTA CACAGCGTCT TCTACAGACA 1500

CCAACCTTCC CAGCAATTCA TCACGTCTTC CTGCCTCCCT CAGAAGGAAA CGGCAGAGAG 1560

GTGCCGGTGG GGAAAATCTC CTTCACTCCG TCTGAGGTGC TCGGCCACGG CAGTGCAGGA 1620

ACATTTGTCT TCAGGGGCAA CTTTGATGGT CGTGACGTAG CCGTGAAGCG AATCCTGCCA 1680

GAGTGCGTCG AGGTGGCAGA ACGTGAAGTG CAGCTCCTCC GAGCCTCCGA CACGCACCCA 1740

AATGTCATCC GGTATTTCTG CACAGAGAGA GACCGCCTCT TCACTTACAT CGCCATCGAG 1800

CTCTGTGCTG CCACCTTGCA ACAGTACGTG GAGGATCCAG CTCGCTTTCC TGAGCTGAGT 1860

CCTGTAAGTC TCCTGGAACA GACCATGTGC GGCCTTTCAC ACCTCCATTC ACTAAATATA 1920

GTCCATCGCG ACCTGAAACC CAGAAACATC CTCCTCTCTG CTCCTAATGC TCTGGGTCAG 1980

GTCCGAGCTC TCATCTCTGA CTTTGGACTC TGCAAAAAGA TCCCAGATGG TCGGAGCAGC 2040

TTCTCTTTGC GATCTGGAAT ACCGGGAACT GAAGGGTGGA TAGCGCCCGA AGTCCTGCGG 2100

GATACCCCGG GAAACAAAAC GACGGCAGCT GTTGACGTCT TCTCAGCAGG CTGTGTCTTC 2160

TACTTTGTGA TCAGCAGGGG GCAGCACCCG TTTGGGGACA CATTGAGAAG ACAGGTTAAC 2220

ATCTTGGCTG GAGAATATTC ACTTTTGCAT TTCAAACAGG GTTTACATGA GGACATCATA 2280

GCACAGAATC TGATCGAGCA AATGATCGCC GCAGCAGCTG AAACCCGCCC TTCTTGCTCC 2340

TGTGTCCTCA AACATCCGTT TTTCTGGAGC CCTGAGAGGC AGCTGCTCTT TTTCCAGGAT 2400

GTGAGCGACC GCATAGAGAA GGAACCGGCC GACAGCCCCA TCGTGCTCAC GCTGGAGAAT 2460

GGAGGAAGGG CTGTGGTTCG CACCAACTGG AGAATGCACA TCTCAGTTCC CCTACAGATA 2520

GACTTGAGGC GGTTCAGAAC CTATAAAGGA AACTCTGTCA GAGATCTGCT GAGAGCCATG 2580

AGGAATAAGA AGCATCACTA CCACGAGTTG CCTTCAGAGG TCCAGGAGAC CCTGGGCGAG 2640

CTGCCCGACG GATTCATTAA CTATTTCACT TCTCGGTTTC CACGGTTACT GATGCACACG 2700

TATGAGGCGC TGCACATCTG CAGCCACGAG AGACTCTTTC ACCCCTATTA T 2751

Domain Profile

S: 1     fspkdvlGkGaeGtvvfrGsfegrevavkrllsefvdlakrevkllresdehpnviryfc  60

         f+p++vlG+G+ Gt+vfrG+f+gr+vavkr+l+e+v++a+rev+llr sd+hpnviryfc

Q: 528   FTPSEVLGHGSAGTFVFRGNFDGRDVAVKRILPECVEVAEREVQLLRASDTHPNVIRYFC  587

         6899********************************************************

S: 61    tekdrqfryialelcaaslqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdl  120

         te+dr f yia+elcaa+lq+yved+      el p+sll+q++ Gl+hlhsl+ivhrdl

Q: 588   TERDRLFTYIAIELCAATLQQYVEDPARF--PELSPVSLLEQTMCGLSHLHSLNIVHRDL  645

         ************************98654..79***************************

S: 121   kpqnilislpdakgklrvlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltke  180

         kp+nil+s+p+a g++r+lisdfGlckk++ G+ssfs rsg++GteGwiape+l++++ +

Q: 646   KPRNILLSAPNALGQVRALISDFGLCKKIPDGRSSFSLRSGIPGTEGWIAPEVLRDTPGN  705

         ************************************************************

S: 181   rltsavdifslGcvfyyvlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedli  240

         ++t avd+fs+Gcvfy+v+s+G+hpfGd l+rq nil ge+sl ++k+  +e++ia++li

Q: 706   KTTAAVDVFSAGCVFYFVISRGQHPFGDTLRRQVNILAGEYSLLHFKQGLHEDIIAQNLI  765

         ************************************************************

S: 241   skmidkdplkrpsakkvlkhplf  263

         ++mi+    +rps ++vlkhp+f

Q: 766   EQMIAAAAETRPSCSCVLKHPFF  788

         **********************9

Domain Sequence
(FASTA)

FTPSEVLGHG SAGTFVFRGN FDGRDVAVKR ILPECVEVAE REVQLLRASD THPNVIRYFC 60

TERDRLFTYI AIELCAATLQ QYVEDPARFP ELSPVSLLEQ TMCGLSHLHS LNIVHRDLKP 120

RNILLSAPNA LGQVRALISD FGLCKKIPDG RSSFSLRSGI PGTEGWIAPE VLRDTPGNKT 180

TAAVDVFSAG CVFYFVISRG QHPFGDTLRR QVNILAGEYS LLHFKQGLHE DIIAQNLIEQ 240

MIAAAAETRP SCSCVLKHPF F 261

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Ciona savignyi"; ?>Echinops telfairi"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 5.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013