EKS-TAR-00196

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00196

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	512.3	8.7E-154	89	382	294

Status

Unreviewed

Ensembl Protein

ENSTRUP00000030254

UniProt Accession

H2TZZ5;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38

Gene Synonyms/Alias

STK38;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000011953	ENSTRUP00000030254	ENSTRUT00000030371

Organism

Takifugu rubripes

Functional Description

Protein Length

471

Protein Sequence
(FASTA)

MAMTSQSSCF SMSNHTKERV TMAKVTLENF YSNLITQHEE REMRQQKLEK VMDQEGLADE 60

EKRMRRSQHA RKETEFLRLK RTRLGLEDFE SLKVIGRGAF GEVRLVQKKD TGHVYAMKIL 120

RKADMLEKEQ VGHIRAERDI LVEADSLWVV KMFYSFQDKM NLYLIMEFLP GGDMMTLLMK 180

KDTLSEEATQ FYIAETVLAI DSIHQLGFIH RDIKPDNLLL DSRGHVKLSD FGLCTGLKRA 240

HRTEFYKNLN HSLPSDLTFQ NMNSKRKAET WKRNRRQLAF STVGTPDYIA PEVFMQNGYN 300

KLCDWWSLGV IMYEMLIGYP PFCSETPQET YRKVMNWRET LIFPPEVPIS EKAKDLILRF 360

CCEEEHRIGA VGVEEIKANP FFEGVDYDHI RERPAAIPIE IKSIDDTSNF DEFPDSDILT 420

PTGTDSLCSS SAAPEADLKN KDWVFVNYTY KRFEGLTARG AIPSYMKSSK R 471

Nucleotide Sequence
(FASTA)

ATGGCAATGA CTAGCCAGAG CTCCTGCTTT TCCATGAGTA ACCACACTAA GGAGAGGGTC 60

ACCATGGCCA AAGTGACCTT GGAGAACTTT TATAGTAACC TCATCACTCA GCATGAGGAA 120

CGAGAAATGA GGCAGCAGAA GCTGGAGAAA GTGATGGACC AGGAAGGATT GGCAGATGAA 180

GAGAAACGTA TGCGACGCTC CCAGCATGCA AGAAAAGAGA CCGAGTTTCT GCGGCTGAAG 240

CGTACTCGAC TTGGCCTGGA GGACTTTGAA TCCCTCAAAG TGATTGGCCG AGGTGCTTTT 300

GGAGAGGTAC GTCTGGTTCA GAAAAAAGAC ACCGGTCACG TCTATGCAAT GAAGATCCTT 360

CGAAAAGCTG ACATGCTCGA AAAAGAACAG GTCGGTCATA TCCGTGCTGA GCGGGACATC 420

CTGGTAGAGG CTGATAGCCT CTGGGTGGTC AAGATGTTCT ACAGTTTTCA GGACAAAATG 480

AACCTCTACC TCATCATGGA ATTCCTACCC GGAGGAGACA TGATGACCCT GCTGATGAAG 540

AAAGACACCC TGAGCGAAGA GGCCACTCAG TTTTATATAG CAGAGACCGT TCTGGCCATT 600

GATTCCATTC ACCAGCTGGG CTTCATTCAC AGAGATATCA AACCAGACAA TCTGCTCCTG 660

GACTCACGGG GCCACGTGAA GTTATCTGAC TTTGGGCTCT GCACAGGACT TAAAAGGGCT 720

CATCGTACCG AGTTCTACAA GAACCTGAAC CACAGCCTTC CCAGTGACCT CACCTTCCAG 780

AATATGAACT CCAAGAGGAA AGCAGAAACC TGGAAGAGGA ACAGGAGACA GCTGGCATTC 840

TCCACTGTGG GGACCCCAGA CTACATTGCA CCAGAGGTCT TCATGCAAAA TGGATATAAC 900

AAGCTCTGTG ATTGGTGGAG CTTAGGTGTC ATCATGTATG AGATGTTGAT AGGTTACCCT 960

CCATTTTGCT CTGAAACTCC TCAAGAAACC TACAGAAAAG TGATGAACTG GCGAGAAACG 1020

CTGATCTTTC CTCCAGAAGT GCCCATATCA GAGAAGGCCA AAGACCTTAT TCTCAGGTTT 1080

TGCTGTGAGG AGGAACACAG GATAGGTGCT GTGGGTGTGG AGGAGATCAA AGCCAACCCT 1140

TTCTTTGAGG GGGTGGACTA CGACCATATA AGGGAGAGAC CTGCTGCCAT TCCCATAGAG 1200

ATCAAAAGCA TTGACGACAC GTCGAACTTC GATGAATTCC CAGATTCTGA CATCCTCACG 1260

CCCACAGGTA CAGACTCACT CTGCTCTTCT TCAGCCGCCC CAGAGGCTGA CCTGAAGAAC 1320

AAGGACTGGG TCTTCGTCAA CTACACCTAC AAGCGCTTTG AAGGGTTGAC CGCACGAGGA 1380

GCCATACCAT CCTATATGAA ATCAAGCAAG AGATGA 1416

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt++vya+kilrk+d+l+k+qv h++aerdil+eads w

Q: 89    FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLW  148

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk nlyl+me+lPGGd+mtll+kk++l+ee+++fyiae+vla++s+h+lGf

Q: 149   VVKMFYSFQDKMNLYLIMEFLPGGDMMTLLMKKDTLSEEATQFYIAETVLAIDSIHQLGF  208

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+d++Gh+kl+dfGlctGlk++hr+e+yk+l+++ ++dl +    +++++

Q: 209   IHRDIKPDNLLLDSRGHVKLSDFGLCTGLKRAHRTEFYKNLNHSLPSDLTF----QNMNS  264

         *************************************************55....55555

S: 181   rkk....kknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPfla  236

         ++k    k+nrr+la+s+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++

Q: 265   KRKaetwKRNRRQLAFSTVGTPDYIAPEVFMQNGYNKLCDWWSLGVIMYEMLIGYPPFCS  324

         5544556*****************************************************

S: 237   etpqetykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         etpqety+kv+nw+etl fp+ev++se+akdli r++++ e+r+g+ Gv+eik++pff

Q: 325   ETPQETYRKVMNWRETLIFPPEVPISEKAKDLILRFCCEEEHRIGAVGVEEIKANPFF  382

         *********************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHVYAMK ILRKADMLEK EQVGHIRAER DILVEADSLW 60

VVKMFYSFQD KMNLYLIMEF LPGGDMMTLL MKKDTLSEEA TQFYIAETVL AIDSIHQLGF 120

IHRDIKPDNL LLDSRGHVKL SDFGLCTGLK RAHRTEFYKN LNHSLPSDLT FQNMNSKRKA 180

ETWKRNRRQL AFSTVGTPDY IAPEVFMQNG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYRKVMNWR ETLIFPPEVP ISEKAKDLIL RFCCEEEHRI GAVGVEEIKA NPFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013