EPS-TAR-00046

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TAR-00046

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	192.5	2.7E-56	785	1030	246

Status

Unreviewed

Ensembl Protein

ENSTRUP00000030752

UniProt Accession

H2U1E0;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP1 (1 of 2)

Gene Synonyms/Alias

PHLPP1 (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000012154	ENSTRUP00000030751	ENSTRUT00000030868
ENSTRUG00000012154	ENSTRUP00000030753	ENSTRUT00000030870
ENSTRUG00000012154	ENSTRUP00000030752	ENSTRUT00000030869

Organism

Takifugu rubripes

Functional Description

Protein Length

1334

Protein Sequence
(FASTA)

TRSLDRKTLL KHRQNMQLQP TDREWVRSDL HRGSIHVHDR LTPSYPRPVL CTMDTTAGEV 60

ALRLSKLCRL RANGGEEAGE SNPTLYVQLH GEAVRRLSPD ERPLQIQSDF LFKLGFKDPW 120

RVQEEGLNTE IGSLLRFYAG KPQSIESSER VQLSGTYNVR KGKLQLPVNR WTRRQVILCG 180

TCLIVSSVKE SQTGKMHILP LIGGKVEEVK KHNHCLAFSS AGPQSQTYYV SFDSFTEHLR 240

WHRHAAKMVS QRINSVDLSC CSLEQLPPNL FYSQDLTHLN LKHNFLSADQ RLQQLQRFSR 300

LRSLNLSNNH LSQFPLAICD IPTLTEVNLS CNYLVSVPCS VGAMTNLQTF LLDGNNLNEL 360

PGELGSLQRL SYLGLSFNHF NHVPQILEQL PSMEKLCMAG NSLETLTLQN FRLLRVKHID 420

LRLNKISSVV PDEPDLLRHV TQLDVRDNRL TELDACVFPK LEMLHCERNR IACLKAKGSF 480

LKGIYASSNE LQQLVISPVP SNLTYMDISR NHMEALPDWL CEAKKLEVLD VSHNLIAELP 540

ARLLCSNSLR KLSVGYNQLQ KLPERVERPL LEVLDVQHNQ LLELPCNLFL KCDSLRCVNA 600

SANKLEHMPP SSLSEDSHSV LQELYLTNNR LTDKCVPMLT GHTHLRVLHM AYNHLQTFPA 660

SKMAKLEELE EVDLSGNMLK TVPTTIMNCR RMHTLIAHSN SIEVFPEVMQ LMEMKCVDLS 720

CNELSEISLP ENLPPKLQEL DLTGNPRLNL DHKTLEQLNN IRCFRIDPPP TFSSNETTGG 780

PAVWSHGYTE ASGVKNKLCV AALSVNSFCG SREALYGVFD GDRNVEVPYL LQCTMNDVLA 840

EEIHKTKSEE DYMTNTFLVM QRKLGTAGQK LGGSAALCHI RHDPTDPGGC FTLTAANVGK 900

CQAILCRDGK PLPMSLLHNI GLEEEYRRIR QHRAIITEDN KVNGVTDSTR IMGYSFLYPA 960

VLPCPHVQTI TLTSQDEFFI LGSRGLWDAV SPAEAVEAVR NVPDGLAAAK KLCTLAQGYG 1020

CTDSISAVVV QLSVSEDCCS CCCSEPAQPP PSPGLGPYPS SSSAIKERPS DGSLPVPPSS 1080

CSEISSEIST SEMSSEVGST ASSDEPPYLF PSSELPSARS CCALHPVCLA GSFQRQLSSA 1140

TFSSALSDNG LDSEDEEPIA GVFSNGSRVE VEADVHCLKA ECSPQTSPPS SSTQEPALLT 1200

LPPPPPPPPC TPEPPEEGIN LNFGEAENGL ERDESWQGVG AGAADGGKLA GKRRVNGSVA 1260

QQEQSHNLIE VAADAPSKKP GGYFTAPAQP DPDDQFIIPP ELEEEVKEIM KQHQQRQQKP 1320

AGSEQPSDYY DTPL 1334

Nucleotide Sequence
(FASTA)

ACTCGGAGTT TGGACCGGAA GACCCTGCTG AAACACCGAC AGAACATGCA GCTGCAGCCC 60

ACCGACCGCG AGTGGGTGAG ATCGGACCTC CATCGGGGTT CCATCCATGT CCACGACAGA 120

CTGACGCCTT CATATCCCAG ACCGGTTCTT TGCACGATGG ACACCACGGC CGGCGAGGTG 180

GCGCTCCGTC TGAGCAAACT CTGCAGGCTA AGAGCAAACG GAGGTGAAGA AGCCGGTGAG 240

TCCAACCCCA CACTGTATGT ACAGCTGCAC GGCGAAGCCG TCAGGAGACT TAGTCCAGAT 300

GAGAGGCCTC TGCAGATCCA AAGCGACTTT CTCTTTAAGC TTGGATTTAA GGACCCCTGG 360

AGAGTTCAAG AGGAAGGCCT TAACACAGAA ATTGGTTCCT TGCTCCGTTT CTATGCAGGG 420

AAGCCCCAAA GCATCGAGAG CTCAGAGCGG GTCCAGCTGT CGGGCACTTA TAATGTTCGG 480

AAAGGGAAAC TCCAGCTGCC GGTGAACCGC TGGACCAGAC GTCAGGTCAT TCTGTGCGGC 540

ACCTGTCTCA TCGTCTCCTC CGTCAAGGAG AGCCAAACGG GGAAGATGCA CATCTTGCCA 600

CTCATCGGAG GAAAAGTGGA GGAGGTGAAG AAGCACAATC ACTGCTTGGC GTTCAGCTCA 660

GCGGGGCCTC AGAGTCAGAC CTACTACGTC AGCTTTGACA GCTTCACGGA GCACCTGCGC 720

TGGCACCGAC ACGCTGCCAA GATGGTGTCT CAGAGGATCA ACTCGGTGGA TCTGTCCTGC 780

TGCAGCCTGG AGCAGCTCCC CCCCAATCTG TTCTACAGCC AGGACCTCAC TCACCTCAAT 840

CTTAAACACA ACTTCCTGTC TGCTGATCAG CGGCTGCAGC AGTTGCAGAG GTTTTCTCGT 900

CTGCGGAGCC TCAACCTGTC CAACAACCAC CTGAGTCAGT TTCCTCTGGC CATTTGTGAC 960

ATTCCCACAC TGACAGAGGT CAACCTGAGC TGCAACTACC TGGTCTCTGT CCCGTGTTCT 1020

GTGGGAGCGA TGACAAATTT GCAGACGTTC CTGTTGGATG GTAACAACCT AAATGAGCTG 1080

CCTGGGGAGC TTGGATCCCT CCAGAGGCTG AGCTACTTGG GCCTTTCTTT CAACCACTTC 1140

AACCACGTGC CCCAAATCCT GGAGCAGTTA CCCTCCATGG AGAAGTTGTG CATGGCTGGA 1200

AACAGCCTGG AAACACTCAC CCTGCAGAAT TTCCGACTGC TTCGTGTCAA ACACATCGAT 1260

CTGAGGTTGA ATAAGATCTC CAGCGTGGTC CCAGATGAGC CCGACCTGCT CAGACACGTG 1320

ACCCAGCTGG ACGTACGGGA CAACAGGCTG ACGGAGCTCG ACGCCTGCGT CTTCCCCAAG 1380

CTGGAGATGC TCCACTGCGA GAGGAACCGC ATCGCCTGCC TCAAGGCCAA AGGTTCCTTT 1440

CTTAAAGGCA TCTACGCCTC CAGCAACGAG CTGCAGCAAC TGGTTATCAG CCCCGTGCCC 1500

TCCAATCTCA CTTACATGGA CATTTCGAGG AATCATATGG AGGCCTTGCC AGACTGGCTG 1560

TGTGAAGCTA AGAAACTCGA AGTTCTGGAT GTGAGCCATA ACCTAATCGC TGAACTCCCA 1620

GCACGGTTGC TCTGCAGCAA CAGTCTGAGG AAGCTGAGCG TTGGATACAA CCAGCTGCAG 1680

AAACTGCCTG AAAGGGTGGA GCGCCCCCTG CTGGAGGTTT TAGACGTACA GCACAATCAA 1740

CTATTGGAGC TGCCCTGCAA CCTGTTCCTC AAATGTGACA GCTTAAGATG CGTCAACGCT 1800

TCAGCAAATA AGCTGGAGCA CATGCCGCCA TCCAGCCTGT CGGAGGACAG CCACAGTGTT 1860

CTGCAGGAAC TCTACCTCAC CAATAACCGG CTCACGGACA AGTGTGTGCC CATGCTGACC 1920

GGCCACACAC ACCTGCGCGT TCTGCACATG GCTTACAATC ATCTCCAGAC TTTCCCAGCC 1980

AGTAAAATGG CAAAGTTGGA GGAGTTGGAG GAGGTGGACC TGAGCGGGAA CATGCTGAAG 2040

ACCGTGCCCA CCACCATCAT GAACTGTCGG CGGATGCACA CGCTCATCGC CCACTCCAAC 2100

TCCATCGAGG TCTTTCCAGA AGTCATGCAG CTGATGGAGA TGAAATGTGT AGATCTGAGC 2160

TGCAATGAAC TGAGCGAGAT CAGCCTGCCT GAAAATCTGC CTCCCAAGCT CCAGGAGCTG 2220

GACCTGACAG GAAATCCTCG TCTGAATCTG GACCACAAGA CCCTTGAGCA ACTCAATAAT 2280

ATTCGCTGCT TCCGTATTGA TCCACCACCA ACCTTTTCAT CGAACGAGAC AACTGGTGGG 2340

CCCGCTGTGT GGAGCCACGG CTACACGGAG GCCTCGGGCG TCAAGAACAA GTTGTGCGTG 2400

GCAGCTCTGT CTGTGAACAG CTTCTGCGGC AGCCGGGAGG CTCTGTACGG CGTGTTCGAT 2460

GGAGACAGGA ACGTGGAGGT TCCCTACCTT TTGCAGTGCA CCATGAATGA CGTGTTGGCA 2520

GAAGAAATAC ACAAGACCAA GAGCGAAGAG GACTACATGA CCAACACCTT CCTTGTCATG 2580

CAAAGAAAAC TTGGAACTGC AGGACAGAAA CTGGGCGGCT CAGCAGCTCT GTGTCACATC 2640

CGCCATGACC CGACTGATCC CGGAGGGTGC TTCACACTCA CTGCTGCTAA TGTGGGCAAG 2700

TGCCAGGCCA TCCTGTGCCG TGATGGGAAA CCGTTGCCGA TGTCGCTGCT TCACAATATC 2760

GGGCTCGAGG AGGAGTACAG GAGGATCAGA CAGCACAGGG CCATCATTAC AGAGGATAAC 2820

AAGGTCAATG GTGTGACCGA TTCCACACGT ATCATGGGCT ACTCCTTCCT CTACCCGGCC 2880

GTCCTTCCCT GTCCGCACGT GCAGACAATC ACTCTCACCT CTCAGGATGA ATTCTTCATT 2940

CTGGGTAGCC GGGGCCTATG GGACGCCGTG TCCCCTGCCG AGGCCGTGGA GGCCGTCCGA 3000

AACGTCCCCG ACGGCTTGGC CGCTGCTAAG AAACTGTGCA CGCTGGCGCA GGGTTACGGC 3060

TGCACAGACA GCATCAGCGC TGTTGTGGTC CAGCTGAGTG TGAGCGAAGA CTGCTGCTCC 3120

TGCTGCTGTT CTGAGCCAGC CCAGCCACCT CCGAGCCCAG GCCTGGGCCC CTATCCCTCA 3180

TCCTCCTCTG CCATCAAAGA GAGGCCGTCG GATGGCTCTC TCCCTGTCCC GCCTTCTTCC 3240

TGCAGTGAAA TCAGCAGCGA GATCAGCACG AGTGAAATGA GCAGCGAAGT GGGCTCCACA 3300

GCGTCGTCCG ACGAACCCCC GTACCTGTTC CCGAGCTCAG AGCTGCCCTC CGCGCGCAGC 3360

TGCTGTGCCC TCCACCCTGT CTGCTTAGCG GGATCCTTTC AGAGGCAGCT GTCTAGCGCA 3420

ACCTTCTCCA GCGCACTGTC TGACAATGGG CTGGACAGCG AGGACGAGGA GCCCATCGCA 3480

GGCGTTTTCT CAAATGGAAG CCGTGTGGAA GTAGAAGCAG ATGTCCACTG CCTTAAAGCC 3540

GAGTGCTCTC CCCAAACATC GCCACCCTCG TCCTCCACCC AGGAGCCAGC ACTGTTAACA 3600

CTACCCCCGC CACCACCACC ACCACCGTGC ACCCCAGAGC CCCCGGAGGA GGGGATCAAC 3660

TTGAACTTCG GCGAGGCCGA GAACGGGCTG GAGAGAGACG AGAGTTGGCA GGGAGTCGGA 3720

GCTGGAGCCG CGGATGGAGG AAAGTTGGCG GGTAAAAGGA GGGTCAACGG ATCGGTGGCG 3780

CAGCAGGAGC AGAGCCACAA CCTTATCGAG GTGGCCGCCG ACGCACCGTC GAAAAAGCCT 3840

GGAGGATACT TCACCGCTCC GGCCCAGCCA GACCCCGACG ACCAGTTCAT CATCCCACCA 3900

GAGCTGGAGG AGGAGGTAAA GGAAATCATG AAGCAGCATC AGCAGAGGCA GCAGAAGCCC 3960

GCGGGAAGCG AGCAGCCCTC TGATTACTAC GACACCCCTC TTTAA 4005

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s+++f+ s+e+     ++gv+DG+++ ev + +++++ ++l

Q: 785   SHGYTEASGVKNKLCVAALSVNSFCGSREA-----LYGVFDGDRNVEVPYLLQCTMNDVL  839

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aee+     +++  +++++++Fl ++++l       ++ +k G +a +++i+++

Q: 840   AEEIH----KTKSEEDYMTNTFLVMQRKL------GTAGQKLGGSAALCHIRHDptdpgg  889

         ***99....8999999*************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG+++a+Lcr+gk++++s  H++  e+E++Ri+++ + +++++  +v+Gv+

Q: 890   cfTLTAANVGKCQAILCRDGKPLPMSLLHNIGLEEEYRRIRQHRAIITEDN--KVNGVTD  947

         ********************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R +G  +l+p v p P+v+ ++lts+def+iL+s Glwd vs+ eav++vr+v +

Q: 948   STRIMGYSFLYPAVLPCPHVQTITLTSQDEFFILGSRGLWDAVSPAEAVEAVRNVPD---  1004

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

            +aakkL++la+ +g++d++sa+vv

Q: 1005  -GLAAAKKLCTLAQGYGCTDSISAVVV  1030

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS VNSFCGSREA LYGVFDGDRN VEVPYLLQCT MNDVLAEEIH 60

KTKSEEDYMT NTFLVMQRKL GTAGQKLGGS AALCHIRHDP TDPGGCFTLT AANVGKCQAI 120

LCRDGKPLPM SLLHNIGLEE EYRRIRQHRA IITEDNKVNG VTDSTRIMGY SFLYPAVLPC 180

PHVQTITLTS QDEFFILGSR GLWDAVSPAE AVEAVRNVPD GLAAAKKLCT LAQGYGCTDS 240

ISAVVV 246

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>