EKS-TAR-00356

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00356

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	453.4	7.3E-136	200	487	288

Status

Unreviewed

Ensembl Protein

ENSTRUP00000031637

UniProt Accession

H2U3X0;

Protein Name

Protein Synonyms/Alias

Gene Name

O73801_TAKRU

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000012489	ENSTRUP00000031634	ENSTRUT00000031757
ENSTRUG00000012489	ENSTRUP00000031635	ENSTRUT00000031758
ENSTRUG00000012489	ENSTRUP00000031632	ENSTRUT00000031755
ENSTRUG00000012489	ENSTRUP00000031633	ENSTRUT00000031756
ENSTRUG00000012489	ENSTRUP00000031631	ENSTRUT00000031754
ENSTRUG00000012489	ENSTRUP00000031638	ENSTRUT00000031761
ENSTRUG00000012489	ENSTRUP00000031636	ENSTRUT00000031759
ENSTRUG00000012489	ENSTRUP00000031637	ENSTRUT00000031760

Organism

Takifugu rubripes

Functional Description

Protein Length

498

Protein Sequence
(FASTA)

IQKEGKSLSL ALTVAALCQD KALRCNCTNC EKTGYECETD GACMASTYYV ERKEQHIRIC 60

INRDSLVPPG QPFYCLSAEG LLNTHCCYED YCNSIDLKVP VVPTKEGEWA SSSWGPVELV 120

AVIAGPVFLL CVLLMVGVFL FQYHQRAYSH RQRLEVEDPS CDHIYLPKDK TLQDLIYDMS 180

TSGSGSGLPL FVQRTVARTI VLQEIIGKGR FGEVWRGKWR GGDVAVKIFS SREERSWFRE 240

AEIYQTIMLR HENILGFIAA DNKDNGTWTQ LWLVSDYHEH GSLFDYLNRY SVTIEGMIKL 300

ALSAASGLAH LHMEILGTQG KPGIAHRDLK SKNILVKKNG MCAIADLGLA VRHESITDTI 360

DIAPNQRVGT KRYMAPEVLD ETINMKHFDS FKCADIYALG LVYWEIARRC NAGGIHEEYQ 420

LPYYDLVPSD PSIEEMRKVV CDQKLRPNVP NWWQSYEALR VMGKIMRECW YANGAARLTA 480

LRIKKTLSQL SVEEDIKM 498

Nucleotide Sequence
(FASTA)

ATACAAAAGG AGGGGAAAAG CCTCTCATTA GCTTTAACTG TGGCAGCTCT CTGTCAGGAT 60

AAAGCACTGC GTTGTAACTG CACCAACTGT GAGAAGACCG GCTATGAGTG TGAGACGGAC 120

GGCGCCTGCA TGGCGTCTAC ATATTATGTG GAGAGGAAGG AGCAACACAT CCGAATCTGC 180

ATCAACCGGG ACAGCCTGGT CCCCCCCGGA CAGCCGTTCT ACTGTCTGAG TGCTGAAGGT 240

CTGCTGAACA CACACTGCTG CTACGAAGAT TACTGCAACA GCATCGACCT GAAAGTTCCC 300

GTAGTCCCGA CTAAGGAAGG AGAGTGGGCC AGCAGCTCCT GGGGGCCTGT GGAGCTGGTG 360

GCGGTGATCG CCGGGCCGGT GTTCCTCCTC TGTGTGCTGC TGATGGTCGG CGTCTTCCTC 420

TTCCAGTATC ACCAGAGGGC CTACAGCCAC CGGCAAAGGC TGGAGGTGGA GGACCCGTCC 480

TGTGATCACA TTTACCTGCC CAAAGACAAG ACATTACAGG ACCTCATCTA TGACATGTCC 540

ACCTCTGGTT CGGGCTCTGG TTTGCCCTTG TTTGTGCAGC GGACGGTGGC CAGGACCATC 600

GTGCTGCAGG AGATCATAGG AAAAGGTCGC TTCGGTGAGG TCTGGAGGGG GAAGTGGAGG 660

GGCGGAGACG TGGCCGTGAA GATCTTCTCC TCCAGAGAGG AGCGCTCCTG GTTCAGAGAG 720

GCCGAAATCT ACCAGACAAT CATGCTGCGC CATGAAAACA TCCTGGGATT CATCGCGGCC 780

GACAATAAAG ACAACGGCAC CTGGACTCAG CTGTGGCTGG TGTCCGACTA TCACGAGCAC 840

GGCTCCCTTT TCGACTACCT GAACCGTTAC TCCGTCACCA TCGAGGGCAT GATCAAACTG 900

GCGCTGTCGG CCGCCAGCGG CCTGGCGCAC CTGCACATGG AGATCCTGGG CACTCAGGGC 960

AAACCGGGCA TTGCTCACCG CGACCTCAAA TCAAAGAACA TCCTGGTTAA GAAGAACGGT 1020

ATGTGCGCCA TAGCTGACCT GGGCCTGGCT GTCCGTCACG AATCCATCAC GGATACCATC 1080

GACATCGCCC CAAACCAGCG CGTGGGCACC AAAAGGTACA TGGCCCCCGA GGTTCTGGAT 1140

GAGACCATCA ACATGAAGCA CTTTGATTCC TTCAAGTGTG CTGACATTTA CGCGCTGGGC 1200

CTGGTGTACT GGGAGATCGC ACGGCGCTGC AACGCAGGAG GTATTCACGA GGAGTACCAG 1260

CTGCCATACT ACGACCTGGT GCCCTCCGAC CCCTCCATAG AGGAAATGAG GAAAGTGGTG 1320

TGTGACCAGA AACTCAGGCC CAACGTGCCC AACTGGTGGC AGAGTTATGA GGCCCTGCGC 1380

GTCATGGGAA AGATCATGAG GGAGTGCTGG TACGCCAACG GAGCGGCCAG GCTGACGGCC 1440

CTGCGCATCA AAAAGACCCT GTCTCAGCTC AGCGTGGAGG AGGACATCAA GATGTGA 1497

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfia  60

         + l+e+igkGr+geVw++k+rg +vAvKifs+++e+sw+rE+eiyqt++lrhenil+fia

Q: 200   IVLQEIIGKGRFGEVWRGKWRGGDVAVKIFSSREERSWFREAEIYQTIMLRHENILGFIA  259

         5789********************************************************

S: 61    adkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

         ad+k+++++t+l+lv++yhe+gsL+dyL+r+ +++e +++lals+asGlahLH+ei gt+

Q: 260   ADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYSVTIEGMIKLALSAASGLAHLHMEILGTQ  319

         ************************************************************

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPE  180

         g  Kp iaHRDlkskNilvkk+++c+iaDlGLa+++e+ ++++d+a n++vGtkRYmaPE

Q: 320   G--KPGIAHRDLKSKNILVKKNGMCAIADLGLAVRHESITDTIDIAPNQRVGTKRYMAPE  377

         *..*********************************************************

S: 181   vleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleem  240

         vl+e++n+k+f++fk+aD+Y+lgLv+WE+a+Rc++ ++++eey+lp+++ v+sdPs+eem

Q: 378   VLDETINMKHFDSFKCADIYALGLVYWEIARRCNA-GGIHEEYQLPYYDLVPSDPSIEEM  436

         ***********************************.************************

S: 241   kevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         ++vv+++klrP++p+ w++ eal+++ k+++ecW+a+++aRltalr+kk+l

Q: 437   RKVVCDQKLRPNVPNWWQSYEALRVMGKIMRECWYANGAARLTALRIKKTL  487

         *************************************************97

Domain Sequence
(FASTA)

IVLQEIIGKG RFGEVWRGKW RGGDVAVKIF SSREERSWFR EAEIYQTIML RHENILGFIA 60

ADNKDNGTWT QLWLVSDYHE HGSLFDYLNR YSVTIEGMIK LALSAASGLA HLHMEILGTQ 120

GKPGIAHRDL KSKNILVKKN GMCAIADLGL AVRHESITDT IDIAPNQRVG TKRYMAPEVL 180

DETINMKHFD SFKCADIYAL GLVYWEIARR CNAGGIHEEY QLPYYDLVPS DPSIEEMRKV 240

VCDQKLRPNV PNWWQSYEAL RVMGKIMREC WYANGAARLT ALRIKKTL 288

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013