EKS-TAR-00411

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00411

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	349.3	3.1E-104	26	277	252

Status

Unreviewed

Ensembl Protein

ENSTRUP00000038340

UniProt Accession

H2UN21;

Protein Name

Protein Synonyms/Alias

Gene Name

STK3

Gene Synonyms/Alias

STK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000015001	ENSTRUP00000038340	ENSTRUT00000038477
ENSTRUG00000015001	ENSTRUP00000038343	ENSTRUT00000038480
ENSTRUG00000015001	ENSTRUP00000038342	ENSTRUT00000038479
ENSTRUG00000015001	ENSTRUP00000038341	ENSTRUT00000038478

Organism

Takifugu rubripes

Functional Description

Protein Length

499

Protein Sequence
(FASTA)

MEPSAPKSKL KKLSEDSLTK QPEEVFDVLE KLGEGSYGSV FKAIHKESGQ VVAIKQVPVE 60

SDLQEIIKEI SIMQQCDSPY VVKYYGSYFK NTDLWIVMEY CGAGSVSDII RLRNKTLTEE 120

EIATILKSTL KGLEYLHFMR KIHRDIKAGN ILLNTEGHAK LADFGVAGQL TDTMAKRNTV 180

IGTPFWMAPE VIQEIGYNCV ADIWSLGITS IEMAEGKPPY ADIHPMRAIF MIPTNPPPTF 240

RKPELWSDEF TDFVKKCLVK NPEQRATATQ LLQHPFISQA KPVTILRDLI TEAMEMKAKR 300

QQEQQRELEE EEDNSEEETE VDSHTMVKSG SEGAGTMRAT STMSDGAQTM IEHGSTMLES 360

DLGTMVINSD DDEEEEEDQR SMKRHATPQQ PMRPSFMDYF DKQDSNKAAQ QQENYNHNQA 420

QEPGYHIQSK NVFPDNWKVP QDGDFDFLKN LDFEELQLRL TALDPMMERE IEELRQRYTA 480

KRQPILDAMD AKKRRQQNF 499

Nucleotide Sequence
(FASTA)

ATGGAACCGT CTGCGCCCAA AAGCAAGCTA AAAAAGCTCA GTGAGGACAG CTTGACCAAA 60

CAACCCGAGG AAGTGTTTGA TGTGCTGGAA AAACTTGGTG AAGGTTCCTA TGGCAGTGTT 120

TTTAAAGCCA TTCACAAGGA GTCGGGCCAG GTGGTGGCTA TCAAGCAGGT TCCTGTGGAG 180

TCTGATCTGC AGGAGATCAT CAAGGAGATC TCCATCATGC AGCAGTGTGA CAGCCCCTAT 240

GTCGTGAAGT ACTACGGCAG TTATTTCAAG AACACAGACC TGTGGATTGT CATGGAGTAT 300

TGTGGAGCCG GTTCTGTGTC GGACATCATC AGGCTGCGCA ACAAGACGCT GACAGAGGAA 360

GAGATTGCTA CTATTCTAAA ATCAACTCTG AAGGGTCTTG AGTATCTTCA CTTCATGAGG 420

AAGATTCACC GGGACATCAA GGCAGGAAAC ATCCTCCTCA ACACGGAGGG ACACGCCAAA 480

CTCGCAGACT TCGGAGTTGC CGGACAGCTA ACGGACACAA TGGCAAAGAG AAACACAGTG 540

ATCGGCACGC CATTCTGGAT GGCGCCAGAG GTGATCCAAG AGATCGGGTA CAACTGTGTG 600

GCTGACATCT GGTCCCTTGG CATCACATCT ATAGAGATGG CAGAGGGAAA ACCTCCCTAT 660

GCTGACATCC ATCCGATGAG AGCTATCTTC ATGATCCCCA CCAATCCTCC TCCTACCTTC 720

AGGAAACCCG AGCTTTGGTC CGACGAGTTC ACCGACTTTG TGAAGAAATG TCTCGTCAAG 780

AATCCAGAGC AGAGAGCAAC AGCTACGCAG TTATTGCAGC ACCCGTTCAT CAGCCAGGCC 840

AAACCAGTCA CAATCCTGAG GGATCTGATC ACCGAGGCCA TGGAGATGAA GGCCAAGAGG 900

CAGCAGGAGC AGCAGAGAGA GCTGGAGGAG GAAGAGGACA ACTCTGAGGA GGAGACGGAG 960

GTGGACTCTC ACACGATGGT CAAGTCAGGC TCAGAAGGTG CAGGAACCAT GCGGGCCACC 1020

AGCACCATGA GTGACGGCGC GCAGACCATG ATTGAACACG GCAGCACCAT GTTAGAGTCT 1080

GACCTGGGAA CCATGGTCAT CAACAGCGAC GACGATGAGG AGGAGGAGGA AGACCAGAGA 1140

TCCATGAAGA GACACGCCAC CCCTCAGCAG CCCATGCGTC CATCGTTCAT GGATTATTTT 1200

GACAAGCAGG ACTCGAACAA AGCCGCCCAG CAGCAGGAGA ACTACAACCA CAACCAGGCG 1260

CAGGAGCCTG GCTACCACAT CCAGTCCAAG AACGTCTTCC CGGACAACTG GAAGGTACCT 1320

CAGGATGGAG ATTTTGACTT TCTGAAGAAC CTGGACTTTG AGGAGCTGCA GCTGCGCCTC 1380

ACGGCCTTGG ATCCTATGAT GGAGCGGGAG ATTGAGGAGC TCAGGCAGCG CTATACTGCC 1440

AAAAGACAGC CCATCCTGGA TGCCATGGAC GCCAAGAAGA GAAGGCAGCA GAACTTCTGA 1500

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkhpnive  60

         +++le++g+G++g+v++a +k++g++vaik++ +e+  +l+e++keis+++++++p++v+

Q: 26    FDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVES--DLQEIIKEISIMQQCDSPYVVK  83

         7899*******************************7..9*********************

S: 61    ylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkvi  120

         y++s++k+++lw+vmey+ +Gs+sd+++  ++++l+Ee+ia+il+++lk+LeylH +++i

Q: 84    YYGSYFKNTDLWIVMEYCGAGSVSDIIR-LRNKTLTEEEIATILKSTLKGLEYLHFMRKI  142

         ****************************.99*****************************

S: 121   HrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqeekgYdek  180

         Hrdika+niLl++eg+ kL+dfgva ql++t++kr+tv+gtp+wmAPEvi+  e gY++

Q: 143   HRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQ--EIGYNCV  200

         ***************************************************..9******

S: 181   aDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekclqk  240

         aDiwslGIt+ie+aeg+pP++d++p++a+++i++n+pp++++++ +s+ef++fv+kcl k

Q: 201   ADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWSDEFTDFVKKCLVK  260

         ************************************************************

S: 241   npekRpsasellkhkFl  257

         npe+R++a++ll+h+F+

Q: 261   NPEQRATATQLLQHPFI  277

         ****************7

Domain Sequence
(FASTA)

FDVLEKLGEG SYGSVFKAIH KESGQVVAIK QVPVESDLQE IIKEISIMQQ CDSPYVVKYY 60

GSYFKNTDLW IVMEYCGAGS VSDIIRLRNK TLTEEEIATI LKSTLKGLEY LHFMRKIHRD 120

IKAGNILLNT EGHAKLADFG VAGQLTDTMA KRNTVIGTPF WMAPEVIQEI GYNCVADIWS 180

LGITSIEMAE GKPPYADIHP MRAIFMIPTN PPPTFRKPEL WSDEFTDFVK KCLVKNPEQR 240

ATATQLLQHP FI 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007165	; P:signal transduction

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR011524	; SARAH.
IPR024205	; SARAH_domain.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF11629	; Mst1_SARAH; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS50951	; SARAH; 1.

Prints

Created Date

20-Feb-2013