EKS-TAR-00333

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00333

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PDK1	407.3	7.6E-122	63	323	261

Status

Unreviewed

Ensembl Protein

ENSTRUP00000039873

UniProt Accession

H2USE9;

Protein Name

Protein Synonyms/Alias

Gene Name

PDPK1

Gene Synonyms/Alias

PDPK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000015599	ENSTRUP00000039872	ENSTRUT00000040013
ENSTRUG00000015599	ENSTRUP00000039873	ENSTRUT00000040014

Organism

Takifugu rubripes

Functional Description

Protein Length

529

Protein Sequence
(FASTA)

LFQYDVVPIQ PSVVLCSCSR PSMVRNHPDS CSPLEARVDG ASGSGTQQAA QAPQPRKKKP 60

EDFKFGKILG EGSFSTVVLA REQATGKEYA IKILEKRHII KENKVQYVKR ERDLMSILEH 120

PFFVKLYFTF QDDEKLYFGL SYAKNGELLK YIRKIGSFDE TCTRFYSAEI VCALEYLHNK 180

GIIHRDLKPE NILLSEDMHI QITDFGTAKQ LSSDSKQARA NSFVGTAQYV SPELLTEKSA 240

CKSSDLWALG CIIYQLVAGL PPFRAGNEYL IFQKIIKLEY EFPEKFFPKA KDLVKQLLSQ 300

DPSKRIGCEE MGGYDPLRQH PFFDTISWSD LHLQTPPKLT PYLPAMSEDD EDCYGNYDDL 360

LSQFSNMQVA QSSSSHSLSP HESTAPQRSS SNIEQYIHDL DNNSFELDLQ FTEEEKQLLL 420

DKQTTGNPWH QFVENNLILK MGPVDKRKGL FARRRQLLLT EGPHLYYVDP VNKVLKGEIP 480

WSPELRPEAK NFKTFFVHTP NRTYYLMDPS GNADRWCKKI QEVWRRFYQ 529

Nucleotide Sequence
(FASTA)

CTTTTCCAGT ATGATGTTGT GCCCATTCAG CCCAGTGTTG TCCTCTGTTC ATGCTCGCGT 60

CCATCAATGG TAAGAAACCA CCCCGACTCC TGCTCGCCAC TCGAGGCCCG AGTCGACGGC 120

GCCTCCGGCA GCGGGACGCA GCAGGCAGCG CAGGCGCCGC AGCCCAGGAA GAAGAAGCCG 180

GAGGACTTCA AATTTGGGAA AATCCTCGGC GAGGGCTCCT TCTCGACGGT TGTCCTGGCG 240

AGAGAGCAGG CGACGGGCAA AGAGTATGCA ATTAAAATAT TAGAGAAACG CCATATTATA 300

AAGGAGAACA AGGTGCAGTA CGTGAAGAGG GAGAGAGACC TGATGTCCAT CCTCGAACAC 360

CCGTTCTTCG TCAAGCTCTA CTTCACGTTC CAAGATGACG AGAAGTTGTA TTTCGGCCTC 420

AGCTACGCGA AGAACGGAGA ACTCCTGAAA TACATCCGTA AGATCGGCTC TTTTGACGAG 480

ACCTGCACCC GCTTCTACTC GGCCGAGATC GTCTGTGCGT TGGAATACTT GCACAATAAG 540

GGGATCATCC ACAGGGATCT GAAGCCAGAG AACATCCTCC TGAGCGAGGA CATGCACATC 600

CAGATCACAG ATTTCGGGAC GGCGAAACAG CTGTCATCGG ACAGCAAACA AGCAAGAGCC 660

AACTCCTTTG TTGGAACAGC GCAGTACGTG TCTCCAGAGC TGCTCACGGA GAAATCCGCC 720

TGCAAGAGCT CTGATCTTTG GGCCTTGGGC TGCATCATCT ATCAGTTGGT GGCTGGTTTA 780

CCACCATTCA GAGCAGGAAA CGAGTACCTG ATTTTCCAGA AAATAATAAA ACTGGAGTAC 840

GAGTTTCCGG AGAAGTTCTT TCCCAAAGCC AAGGATCTTG TCAAGCAACT TCTGTCTCAG 900

GACCCTTCAA AGCGGATTGG ATGTGAAGAG ATGGGAGGAT ACGACCCGCT GAGGCAGCAC 960

CCCTTCTTCG ACACCATCTC CTGGAGCGAC CTCCACCTGC AGACCCCCCC GAAGCTCACC 1020

CCCTACCTGC CGGCCATGTC GGAGGACGAC GAGGACTGCT ACGGAAATTA CGACGACCTC 1080

CTGAGCCAGT TCAGCAACAT GCAGGTGGCC CAGTCCAGCT CCTCGCACTC GCTGTCGCCG 1140

CACGAGTCCA CGGCCCCGCA GAGGTCCAGC AGCAACATCG AGCAGTACAT CCACGACCTG 1200

GACAACAACT CCTTCGAGCT GGACCTGCAG TTCACCGAGG AGGAGAAGCA GCTGCTGCTG 1260

GACAAGCAGA CCACCGGCAA CCCCTGGCAC CAGTTCGTGG AGAACAACCT GATCCTGAAG 1320

ATGGGCCCAG TAGACAAGCG AAAAGGTCTT TTCGCCCGGC GGAGACAGCT GCTCCTCACC 1380

GAGGGTCCGC ACCTCTACTA CGTGGATCCT GTCAACAAAG TCCTCAAAGG GGAGATCCCC 1440

TGGTCCCCCG AGCTGCGTCC CGAGGCCAAG AATTTCAAAA CCTTCTTCGT GCACACGCCC 1500

AACCGAACAT ACTATTTGAT GGACCCCAGC GGAAACGCGG ACAGGTGGTG CAAGAAGATC 1560

CAGGAAGTGT GGAGGAGGTT TTACCAG 1587

Domain Profile

S: 1     fkfekelgeGsystvvlarekeskkeyaikvlekryiikekkvkyvtrekevlaklnehp  60

         fkf+k+lgeGs+stvvlare+++ keyaik+lekr+iike+kv+yv+re++ ++ l ehp

Q: 63    FKFGKILGEGSFSTVVLAREQATGKEYAIKILEKRHIIKENKVQYVKRERDLMSIL-EHP  121

         89*****************************************************9.9**

S: 61    givkLyatfqDeeslyfvleyakkGdllellkkvgsfdeactryyaaellsaleflhkkg  120

         ++vkLy+tfqD+e+lyf l+yak+G+ll++++k+gsfde+ctr+y+ae++ ale+lh+kg

Q: 122   FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYSAEIVCALEYLHNKG  181

         ************************************************************

S: 121   iihrDlkpeniLldkdgkilitDfGsakvlepklkedskkeeeesarsksfvGtaeyvsP  180

         iihrDlkpeniLl +d++i+itDfG+ak l++++k+         ar++sfvGta+yvsP

Q: 182   IIHRDLKPENILLSEDMHIQITDFGTAKQLSSDSKQ---------ARANSFVGTAQYVSP  232

         ******************************777766.........9**************

S: 181   elLtdsevskssDlWalgcilyqllaGkpPfraeneylifkkilkleyafpegfpekakd  240

         elLt+++++kssDlWalgci+yql+aG+pPfra neylif+ki+kley+fpe+f++kakd

Q: 233   ELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYEFPEKFFPKAKD  292

         ************************************************************

S: 241   lveklLvkdakerltlee......ikahkff  265

         lv++lL +d+++r+++ee      +++h+ff

Q: 293   LVKQLLSQDPSKRIGCEEmggydpLRQHPFF  323

         ******************************9

Domain Sequence
(FASTA)

FKFGKILGEG SFSTVVLARE QATGKEYAIK ILEKRHIIKE NKVQYVKRER DLMSILEHPF 60

FVKLYFTFQD DEKLYFGLSY AKNGELLKYI RKIGSFDETC TRFYSAEIVC ALEYLHNKGI 120

IHRDLKPENI LLSEDMHIQI TDFGTAKQLS SDSKQARANS FVGTAQYVSP ELLTEKSACK 180

SSDLWALGCI IYQLVAGLPP FRAGNEYLIF QKIIKLEYEF PEKFFPKAKD LVKQLLSQDP 240

SKRIGCEEMG GYDPLRQHPF F 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR011993	; PH_like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013