EKS-TAR-00022

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00022

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	489.4	6.5E-147	24	291	268

Status

Unreviewed

Ensembl Protein

ENSTRUP00000040177

UniProt Accession

H2UTA4;

Protein Name

Protein Synonyms/Alias

Gene Name

PHKG2

Gene Synonyms/Alias

PHKG2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000015722	ENSTRUP00000040177	ENSTRUT00000040319
ENSTRUG00000015722	ENSTRUP00000040178	ENSTRUT00000040320

Organism

Takifugu rubripes

Functional Description

Protein Length

395

Protein Sequence
(FASTA)

MTKDIVVGDE LPDWVGAKEF YQKYDPKEVI GRGVSSVVRR CVHRHTGQEL AVKIIEITAE 60

KMTAQQLEEV KTSTLKEIQV LNMVKGHASI ITLIDSYEST TFIFLVFDLM RRGELFDYLT 120

EKVTLSEKET RSIMRALLEA VQYLHSLNIV HRDLKPENIL LDDQGHIKLS DFGFSVQLQP 180

GEKLKELCGT PGYLAPEILK CSMDDMHPGY GKEVDLWACG VILFTLLAGS PPFWHRKQML 240

MLRMIMEGQY QFSSPEWDDR SDTVKDLISR LLVLEPAARL TAEQALAHPF FRLYQKEDVR 300

LFSPRKTFRV LIVSVLACIR IYSRYRRVRP LTRDVLARDP YSIRGVRKLI DGCAFRIYGH 360

WVKKGEQQNR AALFQNTAKI MLLGLEDFDT FESTW 395

Nucleotide Sequence
(FASTA)

ATGACCAAAG ATATTGTTGT CGGAGATGAA TTGCCAGACT GGGTGGGGGC CAAGGAATTC 60

TACCAGAAAT ATGACCCAAA GGAGGTGATT GGCAGGGGGG TTAGCAGTGT GGTGCGCAGG 120

TGCGTGCACA GACACACGGG TCAGGAGCTG GCGGTGAAGA TTATAGAGAT TACAGCAGAG 180

AAGATGACCG CTCAGCAGCT GGAAGAGGTG AAGACCTCCA CACTGAAAGA GATCCAGGTC 240

CTCAACATGG TGAAGGGGCA CGCTTCCATC ATAACTCTCA TTGACTCCTA TGAATCGACC 300

ACCTTCATAT TTTTAGTCTT TGACCTCATG AGGAGAGGAG AGCTGTTTGA CTACCTAACA 360

GAAAAAGTTA CTCTGAGTGA GAAGGAAACC AGGAGTATTA TGCGAGCTCT GCTGGAGGCT 420

GTACAGTACC TCCACTCTCT CAACATTGTC CACCGTGACC TAAAGCCTGA GAACATTCTG 480

TTGGATGATC AAGGACACAT TAAACTGTCT GACTTTGGGT TCTCTGTGCA GCTGCAGCCT 540

GGTGAAAAAC TTAAAGAGCT CTGTGGGACA CCTGGTTATT TAGCCCCTGA AATACTAAAG 600

TGTTCGATGG ATGACATGCA TCCAGGCTAT GGAAAAGAAG TCGATCTGTG GGCCTGTGGA 660

GTCATTCTTT TTACCTTACT GGCTGGCTCA CCACCATTCT GGCACCGCAA ACAGATGCTG 720

ATGCTGAGGA TGATAATGGA GGGCCAATAT CAGTTCAGCT CTCCGGAGTG GGATGACAGG 780

TCTGACACTG TCAAAGATCT GATATCCAGA CTGCTGGTTT TGGAACCAGC TGCCCGTCTC 840

ACAGCTGAGC AAGCACTAGC GCATCCTTTC TTTAGGCTAT ATCAGAAGGA AGACGTGCGG 900

CTCTTCAGTC CAAGAAAAAC ATTTAGGGTG TTGATAGTTA GTGTGCTAGC CTGTATCAGG 960

ATCTACAGCC GTTACCGAAG GGTGCGGCCT CTGACTCGGG ACGTACTGGC CAGAGATCCC 1020

TACTCCATAC GCGGTGTCCG CAAACTCATC GACGGCTGCG CCTTCCGCAT CTATGGACAC 1080

TGGGTGAAAA AGGGGGAGCA GCAGAATCGA GCTGCCCTCT TTCAGAACAC AGCTAAGATC 1140

ATGCTGCTGG GCCTAGAAGA CTTTGACACA TTCGAGAGCA CGTGG 1185

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         y+pke++GrGvssvvrrc++++tgqe avkii+++aek++ ++++e++ +tlke+++l+

Q: 24    YDPKEVIGRGVSSVVRRCVHRHTGQELAVKIIEITAEKMTAQQLEEVKTSTLKEIQVLNM  83

         9***********************************************************

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         v Gh sii+l+d+yes++f+flvfdlm++Gelfdyltekvtlseketr+imralleav+y

Q: 84    VKGHASIITLIDSYESTTFIFLVFDLMRRGELFDYLTEKVTLSEKETRSIMRALLEAVQY  143

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lh+ nivhrdlkpenilldd+ +iklsdfGfs+ql++Gekl+elcGtpgylapeilkcsm

Q: 144   LHSLNIVHRDLKPENILLDDQGHIKLSDFGFSVQLQPGEKLKELCGTPGYLAPEILKCSM  203

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         d+ +pGy+kevdlwa+Gvil+tllaGsppfwhrkq+lmlr+imeG+yqf+spewdd+s++

Q: 204   DDMHPGYGKEVDLWACGVILFTLLAGSPPFWHRKQMLMLRMIMEGQYQFSSPEWDDRSDT  263

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         vkdlis+llv++p +rltae+alahpff

Q: 264   VKDLISRLLVLEPAARLTAEQALAHPFF  291

         ***************************8

Domain Sequence
(FASTA)

YDPKEVIGRG VSSVVRRCVH RHTGQELAVK IIEITAEKMT AQQLEEVKTS TLKEIQVLNM 60

VKGHASIITL IDSYESTTFI FLVFDLMRRG ELFDYLTEKV TLSEKETRSI MRALLEAVQY 120

LHSLNIVHRD LKPENILLDD QGHIKLSDFG FSVQLQPGEK LKELCGTPGY LAPEILKCSM 180

DDMHPGYGKE VDLWACGVIL FTLLAGSPPF WHRKQMLMLR MIMEGQYQFS SPEWDDRSDT 240

VKDLISRLLV LEPAARLTAE QALAHPFF 268

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013