EKS-TAR-00202

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00202

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TLK	615.2	3.0E-185	254	533	280

Status

Unreviewed

Ensembl Protein

ENSTRUP00000041799

UniProt Accession

H2UXW7;

Protein Name

Protein Synonyms/Alias

Gene Name

TLK2 (1 of 2)

Gene Synonyms/Alias

TLK2 (1 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000016346	ENSTRUP00000041794	ENSTRUT00000041938
ENSTRUG00000016346	ENSTRUP00000041795	ENSTRUT00000041939
ENSTRUG00000016346	ENSTRUP00000041796	ENSTRUT00000041940
ENSTRUG00000016346	ENSTRUP00000041797	ENSTRUT00000041941
ENSTRUG00000016346	ENSTRUP00000041798	ENSTRUT00000041942
ENSTRUG00000016346	ENSTRUP00000041799	ENSTRUT00000041943

Organism

Takifugu rubripes

Functional Description

Protein Length

564

Protein Sequence
(FASTA)

HCVFRKKQMS DKATQSDLTI EKLTAMENNK NSDLEKKEGR IDDLLRANCD LRRQIDEQQK 60

MLERYKERLN KCVTMSKKLL IEKSKQEKMA CRDKSMQDRL RLGHFTTVRH GASFTEQWTD 120

GYAFQNLIKQ QERINSQRED IERQRKLLAK RKPPSMAQTP PLSLEQNKRK SKTNGTESEA 180

HVPHLQCTLS QAEYHEQEEI FKLRLGHLKK EEAEIQAELE RLERVRNLHI RELKRIHNED 240

NSQFKDHPTL NDRYLLLHLL GRGGFSEVYK AFDLTEQRYV AVKIHQLNKN WRDEKKENYH 300

KHACREYRIH KELDHPRIVK LYDYFSLDTD SFCTVLEYCE GNDLDFYLKQ HKLMSEKEGR 360

SIIMQIVNAL KYLNEIRPPI IHYDLKPGNI LLVNGTACGE IKITDFGLSK IMDDDSYNSV 420

DGMELTSQGA GTYWYLPPEC FVVGKEPPKI SNKVDVWSVG VIFYQCLYGR KPFGHNQSQQ 480

DILQENTILK ATDVQFPPKP VVTPEAKAFI RRCLVYRKED RIDVHQLASD PFLMPHIRKS 540

VASSGTSSMA VASTSSSSNS SASN 564

Nucleotide Sequence
(FASTA)

CATTGCGTGT TTAGAAAGAA GCAGATGTCA GACAAAGCCA CACAGTCTGA CCTTACTATA 60

GAGAAGTTAA CAGCAATGGA GAATAACAAG AACTCTGACC TAGAGAAGAA GGAGGGACGG 120

ATAGACGACT TACTGCGGGC AAATTGTGAC CTAAGGAGAC AGATTGATGA GCAGCAGAAG 180

ATGCTGGAAC GTTACAAGGA ACGCTTGAAT AAGTGTGTGA CCATGTCCAA GAAGTTACTG 240

ATTGAAAAAT CCAAACAGGA GAAGATGGCA TGCCGGGATA AAAGCATGCA GGACAGGCTT 300

CGGCTTGGTC ACTTTACCAC AGTGAGACAT GGAGCGTCAT TCACCGAGCA GTGGACAGAT 360

GGATATGCCT TCCAAAATCT TATCAAACAA CAGGAAAGGA TTAATTCCCA GCGAGAGGAC 420

ATTGAAAGGC AGAGGAAGCT CCTGGCCAAA CGCAAGCCAC CCTCCATGGC CCAGACTCCA 480

CCGCTAAGCC TGGAGCAAAA CAAACGCAAA AGCAAGACAA ATGGAACAGA GAGTGAAGCT 540

CATGTGCCTC ATTTACAGTG TACGTTGTCA CAGGCAGAGT ACCATGAACA AGAGGAAATC 600

TTTAAATTGA GACTCGGCCA TCTTAAGAAG GAAGAGGCAG AGATCCAGGC AGAGCTTGAG 660

AGGCTGGAGC GAGTGCGGAA CTTACATATT CGCGAGTTGA AAAGGATCCA CAATGAGGAT 720

AATTCACAAT TCAAAGATCA CCCGACGCTA AATGACCGAT ACTTGCTTCT GCATTTACTC 780

GGAAGGGGAG GTTTTAGTGA AGTTTATAAG GCCTTTGACC TCACAGAGCA AAGGTATGTT 840

GCAGTCAAAA TCCACCAGTT AAACAAGAAC TGGAGAGATG AGAAAAAGGA AAATTATCAC 900

AAACACGCAT GCAGAGAATA TAGAATTCAC AAGGAGCTGG ACCATCCAAG AATAGTTAAA 960

CTCTATGACT ACTTTTCACT CGACACCGAC TCGTTCTGCA CGGTCCTGGA GTACTGTGAG 1020

GGCAATGACT TGGACTTCTA CCTGAAGCAG CACAAACTTA TGTCAGAGAA AGAAGGACGC 1080

TCCATCATCA TGCAGATCGT TAATGCCCTC AAGTACCTGA ATGAGATCAG ACCGCCCATT 1140

ATCCACTATG ACCTGAAGCC CGGTAACATC CTGTTGGTGA ATGGCACCGC CTGTGGAGAG 1200

ATCAAGATCA CAGACTTTGG CCTGTCGAAG ATCATGGACG ATGACAGCTA TAACTCCGTA 1260

GATGGGATGG AGCTGACGTC ACAGGGAGCA GGAACATACT GGTACTTGCC CCCTGAATGC 1320

TTTGTGGTTG GAAAGGAGCC ACCTAAAATC TCCAATAAGG TGGATGTGTG GTCTGTGGGA 1380

GTCATTTTCT ACCAGTGTCT GTATGGCCGC AAGCCCTTTG GCCATAACCA GTCCCAGCAG 1440

GACATCCTTC AGGAGAACAC CATCCTGAAG GCAACCGATG TGCAGTTTCC TCCTAAGCCA 1500

GTAGTCACAC CTGAAGCTAA GGCCTTTATA AGGCGCTGTC TAGTGTACCG AAAGGAGGAC 1560

CGCATCGACG TGCACCAACT GGCCAGCGAC CCCTTCCTCA TGCCTCACAT CCGGAAGTCT 1620

GTAGCTTCCT CCGGCACCTC GAGCATGGCC GTGGCTTCCA CATCCAGCTC CTCCAACAGC 1680

AGCGCCTCAA ACTGA 1695

Domain Profile

S: 1     ylllkllgkggfsevykafdlkeqryvavkihqlnkdwkdekkenyvkhalreyrihkel  60

         ylll+llg+ggfsevykafdl+eqryvavkihqlnk+w+dekkeny+kha+reyrihkel

Q: 254   YLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKEL  313

         9***********************************************************

S: 61    dhprivklydllsldtdsfctvleyvegndldfylkqhkllsekearsiimqivsalkyl  120

         dhprivklyd++sldtdsfctvley+egndldfylkqhkl+seke rsiimqiv+alkyl

Q: 314   DHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEGRSIIMQIVNALKYL  373

         ************************************************************

S: 121   neikppiihydlkpgnillvegtacgeikitdfglskimdddsydsddgleltsqgagty  180

         nei+ppiihydlkpgnillv+gtacgeikitdfglskimdddsy+s+dg+eltsqgagty

Q: 374   NEIRPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTY  433

         ************************************************************

S: 181   wylppecfvvgkeppkisnkvdvwsvgvifyqclygkkpfghnqsqqdileentilkate  240

         wylppecfvvgkeppkisnkvdvwsvgvifyqclyg+kpfghnqsqqdil+entilkat+

Q: 434   WYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATD  493

         ************************************************************

S: 241   vqfpskpvvsseakafirrclayrkedridvqqlakdeyl  280

         vqfp+kpvv++eakafirrcl yrkedridv+qla+d++l

Q: 494   VQFPPKPVVTPEAKAFIRRCLVYRKEDRIDVHQLASDPFL  533

         *************************************986

Domain Sequence
(FASTA)

YLLLHLLGRG GFSEVYKAFD LTEQRYVAVK IHQLNKNWRD EKKENYHKHA CREYRIHKEL 60

DHPRIVKLYD YFSLDTDSFC TVLEYCEGND LDFYLKQHKL MSEKEGRSII MQIVNALKYL 120

NEIRPPIIHY DLKPGNILLV NGTACGEIKI TDFGLSKIMD DDSYNSVDGM ELTSQGAGTY 180

WYLPPECFVV GKEPPKISNK VDVWSVGVIF YQCLYGRKPF GHNQSQQDIL QENTILKATD 240

VQFPPKPVVT PEAKAFIRRC LVYRKEDRID VHQLASDPFL 280

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013