EKS-TAR-00488

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00488

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/MLK	287.9	1.6E-85	463	718	256

Status

Unreviewed

Ensembl Protein

ENSTRUP00000045084

UniProt Accession

H2V793;

Protein Name

Protein Synonyms/Alias

Gene Name

FPGT-TNNI3K

Gene Synonyms/Alias

FPGT-TNNI3K;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000017590	ENSTRUP00000045084	ENSTRUT00000045236
ENSTRUG00000017590	ENSTRUP00000045083	ENSTRUT00000045235
ENSTRUG00000017590	ENSTRUP00000045082	ENSTRUT00000045234

Organism

Takifugu rubripes

Functional Description

Protein Length

835

Protein Sequence
(FASTA)

MGNYKTRPSQ TCTDEWKKKV GESYAVIIEK LDDDLQLKDS ELVDLRLAFS SDEAFQKVNL 60

SYRTEKGLSL LHLCCVCGGN KAHIRALILK GLRPSRLSRN GFTALHLAAY KDNAELVTAL 120

LHGGSDVQQV GYGALTALHV ATLAGHHEAT DILLQHGANV NVQDAVFFTP LHIASCYGHE 180

QIAKLLLKFA ADENVSGEVG DRPLHLAAAK GFLSIVKLLL VEGSKAKMNA KDNEDHIPLH 240

FSARFGHHEV VRFLLEGQFD VQPHAVNIYG DTPLHLACYN GKFEAVKEIV QLSGTDGLSK 300

ENIFSETVLH SACTYGKDLE MVKFLLSQNA MSINHQGRDG HTALHSACFH GHIRLVQFLL 360

DNGADMNLVA CDPSRSSGEK DEQTCLMWAY EKGHDAIVTL LKHYKRPDDS PCNEYSQPGG 420

DGSYVSVPSP LGKIKSMTKE KAEVLLLRVS LPSQFHLQLS DLEFNEIIGS GSFGQVYRGK 480

CRNKIVAIKR YRANTYCSKS DVDMFCREVS ILCCLNHPCI IQFVGACLDD PSQFAIVTQY 540

VSGGSLFALL HEQKRLIDLQ SKLIIAIDVA KGMEYLHNLT QPIIHRDLNS HNILLYEDGH 600

AVVADFGESR FLQSVDEDNM TKQPGNLRWM APEVFTQCTR YSVKADMFSY ALCLWELFTG 660

EIPFAHLKPA AAAADMAYHH IRPPIGYSIP KPISALLMRG WYACPEDRPE FSEVVSSLEE 720

CLSNVELMSP ASSNSSGSLS PSSSSDCLLG RGGPGRSHVA ALRSRFELEY ALNTRAYAFW 780

SQSERRRASG GVSLEEVRRN MQLSPIDRNG YVSDPMSTMR YCSSFSSGGS FEDSN 835

Nucleotide Sequence
(FASTA)

ATGGGAAATT ACAAAACCAG GCCATCCCAG ACGTGCACAG ATGAGTGGAA GAAGAAGGTG 60

GGAGAGTCGT ATGCTGTGAT CATTGAGAAG TTGGACGATG ACCTCCAGCT CAAAGACAGC 120

GAGCTTGTGG ATCTCAGACT TGCTTTCAGT TCTGACGAAG CTTTCCAGAA AGTGAATCTG 180

AGCTACAGGA CTGAGAAAGG GCTGTCGCTG CTGCATCTTT GCTGCGTATG TGGAGGCAAC 240

AAGGCCCACA TCCGCGCGCT AATCCTGAAA GGCCTGCGTC CGTCCCGACT GTCCAGGAAT 300

GGCTTCACCG CCCTCCATCT TGCCGCCTAC AAGGATAACG CCGAGCTGGT GACCGCGCTT 360

CTCCATGGGG GGTCAGATGT GCAGCAGGTG GGCTACGGTG CCCTCACCGC CCTGCATGTG 420

GCCACACTGG CTGGCCATCA TGAGGCAACA GATATCCTCC TGCAGCACGG AGCTAACGTC 480

AACGTTCAGG ATGCTGTGTT CTTCACCCCG CTGCATATCG CCTCTTGTTA CGGCCACGAG 540

CAGATCGCAA AGCTGCTGCT GAAGTTTGCG GCGGATGAGA ATGTGAGTGG TGAGGTGGGC 600

GACCGTCCTC TTCACCTGGC CGCAGCCAAA GGTTTCCTGA GCATCGTCAA ACTGCTGCTG 660

GTGGAGGGAA GCAAAGCCAA AATGAATGCC AAGGACAACG AAGATCACAT TCCGCTCCAC 720

TTTAGCGCCC GCTTTGGTCA TCATGAGGTG GTCCGCTTCC TCCTGGAGGG CCAATTTGAC 780

GTGCAGCCAC ACGCTGTCAA CATCTATGGG GACACGCCGT TGCACTTGGC TTGTTACAAT 840

GGGAAATTTG AGGCGGTGAA GGAGATCGTG CAGCTCTCTG GTACAGACGG CCTGTCGAAA 900

GAGAACATAT TCAGCGAGAC CGTACTTCAC AGTGCGTGCA CCTATGGAAA AGACCTGGAG 960

ATGGTGAAGT TCCTGTTGAG CCAGAACGCA ATGAGCATCA ACCACCAGGG CAGAGATGGA 1020

CACACAGCTC TGCACAGTGC CTGTTTTCAC GGACACATCC GCCTGGTGCA GTTCCTGCTG 1080

GACAACGGGG CAGACATGAA CCTGGTCGCC TGTGACCCCA GCAGGTCCAG CGGGGAAAAA 1140

GATGAGCAGA CCTGCCTGAT GTGGGCTTAT GAAAAAGGTC ACGATGCCAT CGTCACCTTA 1200

CTGAAACACT ACAAACGTCC CGATGACTCT CCCTGCAACG AGTACTCCCA GCCGGGAGGG 1260

GACGGCTCCT ATGTTTCCGT CCCTTCTCCT CTGGGAAAGA TCAAAAGCAT GACGAAAGAG 1320

AAAGCCGAAG TGCTCCTCCT CAGGGTCAGC CTCCCGTCGC AGTTCCACCT TCAGCTGTCC 1380

GATCTTGAGT TCAACGAGAT TATCGGATCA GGCTCCTTTG GCCAAGTCTA CAGAGGCAAG 1440

TGCCGAAATA AAATAGTTGC CATCAAACGG TACCGAGCCA ACACCTACTG CTCCAAGTCG 1500

GACGTAGACA TGTTCTGCAG AGAAGTCTCC ATCCTGTGTT GCCTCAATCA CCCCTGCATC 1560

ATCCAGTTTG TAGGGGCCTG TTTGGATGAT CCCAGCCAGT TTGCCATTGT GACCCAGTAC 1620

GTCTCCGGAG GCTCGTTGTT CGCTCTGCTG CATGAACAGA AGAGGCTGAT CGACCTGCAG 1680

TCCAAGCTCA TCATCGCCAT CGACGTGGCC AAGGGTATGG AGTACCTGCA CAATCTCACC 1740

CAGCCCATCA TCCACAGAGA CCTCAACAGC CACAATATCC TGCTGTATGA GGACGGACAT 1800

GCAGTAGTGG CTGATTTTGG AGAGTCCAGA TTTCTGCAGT CTGTGGACGA GGACAACATG 1860

ACCAAGCAGC CGGGGAACCT TCGCTGGATG GCTCCTGAAG TGTTTACGCA GTGTACTCGC 1920

TACTCTGTGA AGGCAGACAT GTTCAGCTAT GCCCTCTGCC TCTGGGAGCT GTTCACTGGA 1980

GAGATTCCCT TTGCTCACTT GAAACCTGCT GCAGCAGCAG CAGACATGGC CTACCACCAC 2040

ATCAGGCCTC CTATTGGTTA TTCCATCCCC AAACCCATCT CTGCACTTCT GATGAGAGGC 2100

TGGTACGCCT GCCCAGAGGA CAGACCCGAG TTCTCAGAAG TGGTTTCCAG CCTGGAGGAA 2160

TGCTTGTCCA ACGTGGAGCT GATGTCTCCA GCCTCCAGCA ACAGCAGCGG CTCCCTCTCT 2220

CCCTCCTCCT CCTCTGACTG CCTGCTGGGC CGCGGAGGAC CCGGGCGGAG CCACGTGGCT 2280

GCCTTGCGCT CTCGTTTTGA GCTCGAGTAT GCGCTCAACA CCCGGGCCTA CGCCTTCTGG 2340

TCTCAGAGTG AGCGTCGCCG TGCGTCCGGG GGGGTTTCAC TGGAGGAGGT GCGGAGGAAC 2400

ATGCAGCTTT CCCCGATCGA TCGCAACGGC TACGTTTCAG ATCCCATGAG CACAATGAGG 2460

TACTGCTCGT CCTTCAGCAG CGGCGGCAGC TTTGAGGACA GCAACTAA 2508

Domain Profile

S: 2     eleeligsgafgkvykakwrkkevavKklreeaee.kekleklereakllsklshpniie  60

         e++e+igsg+fg+vy++k+r+k va+K++r+++++ k+++++++re+++l+ l+hp+ii+

Q: 463   EFNEIIGSGSFGQVYRGKCRNKIVAIKRYRANTYCsKSDVDMFCREVSILCCLNHPCIIQ  522

         789****************************99998999*********************

S: 61    llGvcleepn.lllvmeyveggsLsnvlhekskreidlevlvswalqiArGmaYLhseap  119

         ++G+cl++p+ +++v++yv+ggsL+ +lhe +kr idl+  + +a+++A+Gm+YLh+ ++

Q: 523   FVGACLDDPSqFAIVTQYVSGGSLFALLHE-QKRLIDLQSKLIIAIDVAKGMEYLHNLTQ  581

         **********99******************.99*************************66

S: 120   kkiihrdLksknvLlseekktlkicdFGtarelsk..stkmsaa.gtlawmaPEvl.kee  175

          +iihrdL+s+n+Ll  e+ ++ ++dFG++r+l++  +++m+++ g+l+wmaPEv+ +++

Q: 582   -PIIHRDLNSHNILL-YEDGHAVVADFGESRFLQSvdEDNMTKQpGNLRWMAPEVFtQCT  639

         .9*************.9*****************99877777777***************

S: 176   kvseksDvwSygvvLWelltrevPykdlselaiaykvalkglrlpipsscpeklkkLmke  235

         ++s k+D++Sy+++LWel t+e+P+++l+++a+a+++a++++r+pi+ s+p++++ L+ +

Q: 640   RYSVKADMFSYALCLWELFTGEIPFAHLKPAAAAADMAYHHIRPPIGYSIPKPISALLMR  699

         ************************************************************

S: 236   cwnedpekRpsfseivksl  254

          w ++pe+Rp+fse+v+sl

Q: 700   GWYACPEDRPEFSEVVSSL  718

         ***************9875

Domain Sequence
(FASTA)

EFNEIIGSGS FGQVYRGKCR NKIVAIKRYR ANTYCSKSDV DMFCREVSIL CCLNHPCIIQ 60

FVGACLDDPS QFAIVTQYVS GGSLFALLHE QKRLIDLQSK LIIAIDVAKG MEYLHNLTQP 120

IIHRDLNSHN ILLYEDGHAV VADFGESRFL QSVDEDNMTK QPGNLRWMAP EVFTQCTRYS 180

VKADMFSYAL CLWELFTGEI PFAHLKPAAA AADMAYHHIR PPIGYSIPKP ISALLMRGWY 240

ACPEDRPEFS EVVSSL 256

Keyword

ANK repeat; Complete proteome; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

InterPros

IPR002110	; Ankyrin_rpt.
IPR020683	; Ankyrin_rpt-contain_dom.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR001245	; Ser-Thr/Tyr_kinase_cat_dom.

Pfam

PF00023	; Ank; 1.
PF12796	; Ank_2; 3.
PF07714	; Pkinase_Tyr; 1.

SMARTs

SM00248

; ANK; 10.

Prosites

PS50297	; ANK_REP_REGION; 1.
PS50088	; ANK_REPEAT; 7.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

PR01415

; ANKYRIN.

Created Date

20-Feb-2013