EPS-TAR-00049

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TAR-00049

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	168.7	4.9E-49	783	1029	247

Status

Unreviewed

Ensembl Protein

ENSTRUP00000045249

UniProt Accession

H2V7Q9;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000017657	ENSTRUP00000045251	ENSTRUT00000045403
ENSTRUG00000017657	ENSTRUP00000045250	ENSTRUT00000045402
ENSTRUG00000017657	ENSTRUP00000045248	ENSTRUT00000045400
ENSTRUG00000017657	ENSTRUP00000045249	ENSTRUT00000045401

Organism

Takifugu rubripes

Functional Description

Protein Length

1287

Protein Sequence
(FASTA)

MKRNGSRGCM TRKNRFGSRE RDWLKGDTRR GCVCLYGGTV DPQPATSGPQ ASSAPQTDLQ 60

LVLCSTSTTV EELCAQRDGK SLYVQLHGDL VRRLEPSECP LQMVHDYLAA MGYTDPARVQ 120

QEAANSDLSC LIRFYSECPA NADQQERTLL KGVFSVRKGK SQLHKWAERQ VILCGTCLIV 180

ASVKDSVTGK MHILPLVGGK VEEVRRRQHC LMFSSAGSQA QTYFVNFDTL ADYQRWQRQA 240

SKVVSQTVSM VDLSCYSLEQ VPEYLFYSQD VTHLNLRHNF MSHQGPGGLL NLPRFSQLRS 300

LNLSHNRLGV FPECVCEIFT LTELNLSCNN LKTVPAKIGN LQSLQTLSLD GNHLSSLPEE 360

ASGLAQLNSL GLSFNNFTHV PAVLERLGAV DRLAMAGNRV ESLDLCALAR MSHLKNVDLR 420

LNGLKWVKND SLEVVSQVTQ MDFRDNCLDS LDLSSVSSLE TLHCQRNHLG ALTLSGFTLR 480

TLNASSNRLT TVNVYPVPNQ LTYMDLSQNL LEYLPDWVCD SRKIEMLDVT HNLLTELPSR 540

LLNSLSLRKL LAGNNHLQRV PDLLDHVPLE VLDLQHNRLV ELSESLFYKA LNLKYLNVSA 600

NALGKIPPSS ESEESLSTLQ ELYLTGNNLT ENCGALLVGH QNLRVLHIAY NQLLSFPASK 660

LSKLEQLEEL NLSGNKLKTI PSTVSSCKRL HTLIAHSNHI TVFPEILNLP EIKLVDLSCN 720

ELTEIQLPDS LPATLQELDL TGNNSLTLEH KTLNLFSNIA TLKLDQKSTT TAADVLSASP 780

PWNHGYSEMS GHRNKLCVSV LAVDHFGDGV EACYGVFDGD RNEEVPRLLQ CTMGDVLCEE 840

LQHSSVDSVY MCNTFLTSHR KLGMAGQKLG ASALLCYVHR EQSDSGANFS LTVANVGTCQ 900

AVLCRNGRPV PLSKVYSLEN STEEMERVKL NKAIITEDNK VSGVTCCSRL LGCSYLSPWV 960

LPKPWVHTEH LCSQDEFLIM GNRALFERVS HQEAVCTVQA VRDPRAAAKK LCTLAQSYGC 1020

KDNMEALVVS LHISDGGCTC EPPSSTPVPR GPPPASAPAS ATSGSDATAL SSSSGVVSEF 1080

SSETSASEVG SEAGSTASDE HAAHPERRCS LHPATTLGLF QRQPSSATFS SNQSDNGLDS 1140

DDEAPLEGVI SNGSRLEVEV DIHCCAFQLR SGCPKDLNLE TRGCDYMNGK MRRQNSVVVS 1200

ATNGCLLAVC GREIVDLKKS PSTSSLFGKK LSNGSVVAPE DSHNIIEVAL EAPKKKSGYF 1260

TAPAQQDPED QLIVPPSLEQ EVREQLR 1287

Nucleotide Sequence
(FASTA)

ATGAAGCGGA ACGGGAGTCG CGGCTGCATG ACGAGAAAAA ACAGGTTTGG ATCCCGAGAG 60

AGGGACTGGC TCAAAGGGGA CACCCGGAGG GGCTGCGTGT GTCTCTACGG GGGCACCGTG 120

GATCCACAGC CGGCGACCTC CGGCCCTCAG GCCTCCTCCG CTCCTCAGAC GGACCTGCAG 180

TTGGTGCTCT GCTCCACGAG CACCACGGTG GAGGAGCTGT GCGCTCAGAG GGACGGAAAG 240

AGCCTCTACG TTCAGCTTCA CGGAGACCTC GTCAGGAGGC TGGAGCCCAG CGAGTGTCCC 300

CTCCAGATGG TGCACGACTA CCTGGCCGCG ATGGGCTACA CGGACCCGGC CCGGGTGCAG 360

CAGGAGGCCG CCAACTCCGA CCTGAGCTGC CTGATTCGTT TCTACAGTGA GTGTCCGGCC 420

AACGCGGACC AGCAGGAGCG GACCCTGCTG AAAGGCGTTT TCAGCGTCCG AAAGGGCAAG 480

TCGCAGCTGC ACAAATGGGC GGAGCGGCAG GTCATCCTCT GCGGCACCTG TCTGATCGTG 540

GCCTCTGTCA AGGACAGCGT GACGGGGAAG ATGCACATCC TGCCCCTGGT GGGGGGAAAG 600

GTGGAGGAGG TGAGGCGGAG GCAGCACTGT CTGATGTTCA GCTCCGCCGG GTCACAGGCG 660

CAGACGTACT TTGTCAACTT CGACACGCTG GCGGACTACC AGAGGTGGCA GCGGCAGGCC 720

TCTAAAGTGG TGTCTCAGAC GGTCAGCATG GTCGACCTGT CCTGTTACAG CCTGGAACAG 780

GTGCCTGAAT ACCTTTTTTA CAGTCAGGAT GTCACCCACC TTAACCTGCG ACACAACTTC 840

ATGAGCCATC AGGGACCCGG AGGTCTACTG AACCTCCCCA GGTTTTCCCA GCTGAGGAGC 900

CTGAACTTGT CTCACAACCG ACTGGGGGTT TTCCCCGAAT GTGTGTGTGA GATCTTCACC 960

CTGACTGAAC TCAACCTGTC CTGTAATAAC CTGAAGACCG TCCCCGCTAA GATAGGCAAC 1020

CTTCAGAGCC TGCAGACGCT GTCTTTGGAT GGAAACCACC TCAGCTCCCT CCCCGAGGAG 1080

GCGTCCGGCC TGGCTCAGCT CAACAGTCTC GGGCTGTCTT TCAACAACTT CACCCACGTC 1140

CCCGCCGTGC TGGAGCGGCT GGGCGCCGTG GACAGACTCG CCATGGCTGG AAACAGGGTG 1200

GAGAGTCTGG ACCTGTGTGC TCTGGCTAGA ATGAGCCATC TGAAGAACGT TGACCTCCGG 1260

TTAAATGGGC TGAAGTGGGT GAAGAACGAC AGCCTGGAGG TCGTGAGCCA GGTGACGCAA 1320

ATGGACTTTC GGGACAACTG CTTGGACTCC TTAGACCTGA GCTCTGTCAG CAGTCTGGAG 1380

ACGCTTCACT GCCAGCGCAA CCATCTGGGA GCCCTGACGC TCAGCGGCTT CACCCTGCGC 1440

ACACTCAACG CCAGCAGCAA CCGCCTTACA ACTGTTAATG TCTACCCAGT CCCCAACCAG 1500

CTGACTTACA TGGACCTATC ACAGAACCTG CTGGAGTACC TTCCTGACTG GGTGTGCGAC 1560

AGCAGAAAAA TTGAGATGCT GGACGTCACG CACAACCTCC TGACCGAGCT CCCGTCGAGG 1620

CTGCTCAACA GTTTGAGTCT GAGAAAGCTG CTGGCGGGGA ACAATCATTT GCAGAGAGTG 1680

CCTGACCTAC TTGACCACGT CCCACTGGAA GTCCTGGACC TTCAGCACAA CAGGCTCGTC 1740

GAGCTTTCCG AGAGCTTGTT TTACAAGGCC TTAAACTTAA AATATTTAAA CGTGTCAGCC 1800

AATGCCCTGG GAAAGATTCC TCCCAGCAGT GAATCAGAGG AGAGCCTCAG CACACTCCAG 1860

GAGCTCTACC TGACAGGAAA CAATCTGACC GAGAACTGCG GCGCTCTGTT AGTTGGACAC 1920

CAGAACCTGC GGGTCCTTCA CATCGCCTAC AACCAGTTGC TCTCCTTCCC GGCCAGTAAG 1980

CTGAGCAAGC TGGAGCAGCT GGAGGAGCTA AATCTAAGTG GGAACAAGCT AAAGACCATC 2040

CCCTCCACTG TGTCCAGCTG CAAGAGACTG CACACACTCA TAGCGCACTC CAATCACATT 2100

ACAGTCTTCC CTGAGATCCT CAACCTGCCT GAGATCAAGC TTGTGGATTT AAGCTGCAAC 2160

GAGCTGACGG AGATCCAGTT GCCTGACTCG CTTCCGGCCA CCCTGCAAGA GCTGGATCTG 2220

ACTGGCAACA ACAGCCTCAC GCTGGAACAC AAAACTCTCA ACCTCTTCAG CAACATCGCC 2280

ACCCTGAAAC TAGACCAGAA ATCCACCACA ACAGCAGCAG ACGTGCTGAG CGCGTCCCCT 2340

CCATGGAACC ACGGTTACTC TGAAATGAGC GGCCACAGGA ACAAGCTGTG CGTGTCTGTT 2400

CTGGCTGTTG ACCATTTTGG AGATGGCGTG GAAGCGTGCT ACGGTGTGTT TGACGGAGAC 2460

CGCAACGAGG AAGTGCCTCG GCTTCTCCAG TGCACCATGG GAGATGTCCT GTGTGAGGAG 2520

CTGCAGCACT CCAGCGTGGA CAGCGTGTAT ATGTGCAACA CCTTCCTCAC CTCACACAGA 2580

AAACTCGGCA TGGCCGGCCA GAAGCTTGGG GCTTCGGCCC TGCTGTGTTA TGTTCACCGT 2640

GAGCAGTCAG ACTCTGGAGC CAACTTCAGC CTTACCGTTG CCAATGTGGG CACCTGCCAG 2700

GCGGTGCTGT GCCGGAACGG CCGGCCTGTA CCTCTCTCTA AGGTGTATAG CTTGGAGAAC 2760

AGCACTGAAG AGATGGAGAG GGTTAAGCTC AATAAAGCCA TAATTACTGA GGATAACAAA 2820

GTGAGCGGTG TGACGTGCTG CTCTCGCCTG CTGGGATGCT CTTATCTGTC TCCCTGGGTG 2880

CTTCCGAAGC CCTGGGTGCA CACCGAGCAC CTCTGTTCCC AGGATGAGTT CTTGATCATG 2940

GGGAATCGAG CCCTGTTCGA GCGAGTGTCT CACCAAGAGG CCGTCTGCAC TGTTCAAGCT 3000

GTGCGGGACC CTCGTGCCGC CGCCAAGAAG CTGTGTACAC TCGCCCAGAG CTATGGATGT 3060

AAAGACAATA TGGAGGCTCT GGTGGTGTCC CTGCACATCA GCGATGGCGG CTGCACCTGC 3120

GAGCCGCCCT CCTCCACCCC AGTGCCACGC GGTCCCCCTC CAGCTAGCGC GCCTGCCTCA 3180

GCGACCTCCG GCTCCGACGC GACCGCCCTC TCATCCAGCA GCGGCGTGGT CTCCGAGTTC 3240

AGCAGCGAAA CCTCCGCCTC GGAGGTGGGC AGCGAAGCGG GATCCACCGC GTCAGACGAG 3300

CACGCCGCCC ACCCTGAGCG ACGCTGCAGC CTGCACCCCG CCACCACCCT GGGGCTTTTC 3360

CAGAGACAGC CGTCATCCGC TACGTTCTCT AGCAACCAGT CTGACAACGG CCTGGACAGT 3420

GACGACGAAG CTCCTCTCGA GGGCGTCATC TCCAATGGCA GCAGGTTGGA GGTCGAGGTA 3480

GACATTCACT GCTGCGCCTT CCAGCTGCGG TCTGGATGCC CCAAGGACCT GAACCTTGAA 3540

ACACGAGGCT GCGACTACAT GAACGGGAAA ATGCGCCGGC AGAACAGCGT GGTGGTCTCT 3600

GCTACCAATG GCTGCTTGCT GGCTGTGTGT GGGAGGGAGA TTGTGGACCT TAAAAAATCT 3660

CCCTCCACAT CCAGTCTGTT TGGGAAAAAG CTTTCCAACG GCTCCGTGGT GGCCCCCGAG 3720

GATAGTCATA ATATTATTGA GGTGGCTCTT GAGGCTCCCA AGAAAAAGTC CGGATACTTC 3780

ACTGCCCCGG CGCAGCAGGA CCCTGAGGAC CAGCTGATTG TGCCGCCAAG TCTGGAGCAG 3840

GAAGTTAGGG AGCAGCTCCG A 3861

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++++g rn+++ +v ++++f++  e+      +gv+DG++++ev + +++++ ++l

Q: 783   NHGYSEMSGHRNKLCVSVLAVDHFGDGVEA-----CYGVFDGDRNEEVPRLLQCTMGDVL  837

         789***********************9885.....8************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          eel+    ++   + ++ ++Fl+ +++l       ++ +k G++a+++++  +

Q: 838   CEELQ----HSSVDSVYMCNTFLTSHRKL------GMAGQKLGASALLCYVHREqsdsga  887

         ***99....56666678************......89**************988889999

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcrng +v+ls+ ++ +++ +E+eR++ +++ +++++  +v Gv+

Q: 888   nfSLTVANVGTCQAVLCRNGRPVPLSKVYSLENStEEMERVKLNKAIITEDN--KVSGVT  945

         9******************************99879*********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         ++sR lG+ yl+p+v p+P v+   l s+defli++   l++ vs +eav  v+ v +

Q: 946   CCSRLLGCSYLSPWVLPKPWVHTEHLCSQDEFLIMGNRALFERVSHQEAVCTVQAVRD--  1003

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           +++aakkL++la+++g+kdn+ a+vv

Q: 1004  --PRAAAKKLCTLAQSYGCKDNMEALVV  1029

         ..*********************99997

Domain Sequence
(FASTA)

NHGYSEMSGH RNKLCVSVLA VDHFGDGVEA CYGVFDGDRN EEVPRLLQCT MGDVLCEELQ 60

HSSVDSVYMC NTFLTSHRKL GMAGQKLGAS ALLCYVHREQ SDSGANFSLT VANVGTCQAV 120

LCRNGRPVPL SKVYSLENST EEMERVKLNK AIITEDNKVS GVTCCSRLLG CSYLSPWVLP 180

KPWVHTEHLC SQDEFLIMGN RALFERVSHQ EAVCTVQAVR DPRAAAKKLC TLAQSYGCKD 240

NMEALVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>