EKS-TAR-00203

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00203

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TLK	603.7	1.0E-181	406	684	279

Status

Unreviewed

Ensembl Protein

ENSTRUP00000045615

UniProt Accession

H2V8S7;

Protein Name

Protein Synonyms/Alias

Gene Name

TLK1 (2 of 2)

Gene Synonyms/Alias

TLK1 (2 of 2);

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000017794	ENSTRUP00000045615	ENSTRUT00000045769
ENSTRUG00000017794	ENSTRUP00000045616	ENSTRUT00000045770

Organism

Takifugu rubripes

Functional Description

Protein Length

714

Protein Sequence
(FASTA)

MEELHSLDPR RQELLEARFM GGVSGNTGGS TGSTSGGTKA LTNNECSNHS FGSLGSLSDK 60

ESETPEKKQS ETRGRKRKPD IQSESSQGKL NMRGPKISDY FDFQAGNGSS PVRGVPPAIR 120

SPQNSHSHST QVTAVRQNSS SPPSLTFGDH TIHPKQLAVK QVQTDLTALK LAALESTKNL 180

DLEKKEGRID DLLRANCDLR RQIDEQQKLL EKYKERLNKC ITMSKKLLIE KSTQEKQACR 240

EKSMQDRLRL GHFTTVRHGA SFTEQWTDGY AFQNLVKQQE WINQQREDIE RQRKLLAKRK 300

PPSSSNSQAL TANSEPKQRK TKAMNGAEND PFLKPTLPQL LTLAEYHEQE EIFKLRLGHL 360

KKEEAEIQAE LERLERVRNL HIRELKRINN EDSSQFKDHP TLNERYLLLH LLGRGGFSEV 420

YKAFDLIEQR YAAVKVHQLN KNWREEKKEN YHKHACREYR IHKELDHPRI VKLYDYFSLD 480

TDSFCTVMEY CEGNDLDFYL KQHKLMSEKE ARSIVMQIVN ALKYLNEIKP PIIHYDLKPG 540

NILLVNGTAC GEIKITDFGL SKIMDDDNYG VDGMDLTSQG AGTYWYLPPE CFVVGKEPPK 600

ISNKVDVWSV GIIFFQCLYG RKPFGHNQSQ QDILQENTIL KATDVQFPVK PVASNEAKAF 660

IRRCLAYRKE DRIDVHQMSS DPYLLPHIRR SNSSGNLQTS AASSGLGSSS VISY 714

Nucleotide Sequence
(FASTA)

ATGGAGGAGC TGCACAGTCT GGACCCCCGG AGACAAGAGT TGCTGGAGGC GCGCTTCATG 60

GGTGGGGTCA GCGGCAACAC AGGAGGCAGC ACCGGCAGCA CCAGTGGGGG AACCAAAGCT 120

TTGACTAATA ATGAATGTTC AAATCATAGT TTTGGAAGCC TTGGATCCTT AAGCGACAAG 180

GAATCTGAGA CCCCAGAGAA GAAACAGTCA GAAACGAGAG GCAGAAAAAG GAAACCAGAC 240

ATCCAATCTG AGAGCAGCCA AGGAAAGTTA AACATGCGAG GACCCAAAAT AAGTGATTAT 300

TTTGATTTCC AGGCAGGAAA CGGGTCCAGT CCAGTCAGAG GTGTCCCACC GGCAATCCGT 360

TCACCACAGA ACTCACATTC CCACTCCACT CAGGTCACAG CCGTTAGACA AAATAGTTCT 420

TCTCCCCCTA GTCTGACCTT TGGGGACCAC ACAATTCATC CAAAGCAACT AGCAGTCAAA 480

CAAGTACAGA CTGATCTTAC AGCGTTGAAA TTGGCTGCCC TTGAAAGCAC TAAAAATTTA 540

GACCTTGAGA AGAAGGAGGG AAGAATAGAC GATTTGTTAA GGGCAAACTG TGATCTCAGG 600

AGACAGATAG ACGAACAACA AAAGTTACTT GAAAAGTACA AAGAACGCTT GAATAAATGC 660

ATCACTATGA GCAAAAAGTT GCTCATAGAA AAGAGCACCC AGGAAAAACA GGCATGTCGG 720

GAGAAGAGCA TGCAGGACAG ACTTCGTTTG GGCCACTTCA CCACCGTTAG ACATGGCGCT 780

TCATTTACAG AGCAGTGGAC TGATGGATAT GCCTTCCAGA ATCTAGTGAA ACAGCAAGAG 840

TGGATAAACC AACAGAGAGA GGACATTGAA AGGCAGAGAA AACTGCTTGC CAAGAGGAAA 900

CCGCCATCTT CAAGCAACTC CCAAGCCCTA ACCGCAAACT CTGAGCCAAA GCAACGCAAA 960

ACCAAGGCAA TGAACGGAGC TGAAAATGAT CCCTTTCTAA AACCCACCCT ACCTCAGCTA 1020

CTCACACTAG CAGAGTACCA CGAGCAGGAA GAGATCTTTA AACTGCGTCT GGGGCATCTC 1080

AAAAAGGAAG AAGCTGAAAT CCAGGCAGAG CTGGAGCGTC TGGAGAGGGT GCGCAACCTT 1140

CACATTCGAG AGCTGAAGAG AATAAATAAT GAAGACAGCT CACAATTTAA AGATCATCCA 1200

ACACTGAATG AGCGATATCT GCTCCTCCAC CTTCTAGGAA GAGGGGGGTT TAGTGAAGTT 1260

TACAAGGCTT TTGACTTGAT TGAACAACGA TATGCTGCTG TGAAAGTCCA CCAACTTAAC 1320

AAGAATTGGA GGGAGGAGAA GAAAGAAAAC TATCACAAAC ATGCATGTCG AGAGTACAGA 1380

ATACACAAAG AACTGGACCA CCCACGGATT GTGAAACTTT ACGACTACTT CTCACTGGAC 1440

ACAGACTCGT TTTGCACTGT AATGGAGTAT TGTGAAGGCA ACGACTTGGA TTTCTACTTG 1500

AAGCAACATA AGCTTATGTC TGAGAAAGAG GCACGATCAA TCGTCATGCA GATTGTGAAT 1560

GCTTTAAAAT ATCTGAACGA AATCAAACCC CCCATCATTC ATTACGACCT TAAGCCAGGT 1620

AATATCTTGT TGGTGAATGG CACGGCATGC GGAGAGATCA AAATCACCGA CTTTGGTTTG 1680

TCCAAAATCA TGGATGATGA CAACTACGGT GTAGATGGGA TGGATCTGAC ATCACAGGGT 1740

GCTGGGACTT ATTGGTACCT CCCCCCTGAA TGCTTTGTAG TTGGTAAAGA ACCACCAAAG 1800

ATCTCCAACA AGGTGGATGT TTGGTCTGTT GGCATTATTT TCTTCCAGTG TCTGTATGGA 1860

AGAAAGCCTT TTGGCCACAA TCAGTCACAA CAAGACATTC TGCAAGAGAA CACCATATTG 1920

AAAGCTACAG ATGTTCAATT CCCAGTCAAG CCTGTTGCCA GTAATGAAGC CAAAGCCTTC 1980

ATAAGACGCT GCCTGGCATA CCGGAAGGAG GACCGCATCG ACGTCCACCA AATGTCCAGC 2040

GACCCTTACC TGCTCCCACA CATACGGAGG TCAAACTCGT CTGGAAATCT GCAGACGAGC 2100

GCTGCCAGCT CAGGACTCGG CTCATCTAGC GTCATCTCAT ACTGA 2145

Domain Profile

S: 1     ylllkllgkggfsevykafdlkeqryvavkihqlnkdwkdekkenyvkhalreyrihkel  60

         ylll+llg+ggfsevykafdl eqry+avk+hqlnk+w++ekkeny+kha+reyrihkel

Q: 406   YLLLHLLGRGGFSEVYKAFDLIEQRYAAVKVHQLNKNWREEKKENYHKHACREYRIHKEL  465

         9***********************************************************

S: 61    dhprivklydllsldtdsfctvleyvegndldfylkqhkllsekearsiimqivsalkyl  120

         dhprivklyd++sldtdsfctv+ey+egndldfylkqhkl+sekearsi+mqiv+alkyl

Q: 466   DHPRIVKLYDYFSLDTDSFCTVMEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALKYL  525

         ************************************************************

S: 121   neikppiihydlkpgnillvegtacgeikitdfglskimdddsydsddgleltsqgagty  180

         neikppiihydlkpgnillv+gtacgeikitdfglskimddd+y++d g++ltsqgagty

Q: 526   NEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDNYGVD-GMDLTSQGAGTY  584

         *********************************************99.************

S: 181   wylppecfvvgkeppkisnkvdvwsvgvifyqclygkkpfghnqsqqdileentilkate  240

         wylppecfvvgkeppkisnkvdvwsvg+if+qclyg+kpfghnqsqqdil+entilkat+

Q: 585   WYLPPECFVVGKEPPKISNKVDVWSVGIIFFQCLYGRKPFGHNQSQQDILQENTILKATD  644

         ************************************************************

S: 241   vqfpskpvvsseakafirrclayrkedridvqqlakdeyl  280

         vqfp+kpv s+eakafirrclayrkedridv+q+++d+yl

Q: 645   VQFPVKPVASNEAKAFIRRCLAYRKEDRIDVHQMSSDPYL  684

         **************************************97

Domain Sequence
(FASTA)

YLLLHLLGRG GFSEVYKAFD LIEQRYAAVK VHQLNKNWRE EKKENYHKHA CREYRIHKEL 60

DHPRIVKLYD YFSLDTDSFC TVMEYCEGND LDFYLKQHKL MSEKEARSIV MQIVNALKYL 120

NEIKPPIIHY DLKPGNILLV NGTACGEIKI TDFGLSKIMD DDNYGVDGMD LTSQGAGTYW 180

YLPPECFVVG KEPPKISNKV DVWSVGIIFF QCLYGRKPFG HNQSQQDILQ ENTILKATDV 240

QFPVKPVASN EAKAFIRRCL AYRKEDRIDV HQMSSDPYL 279

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013