EKS-TAR-00312

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TAR-00312

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	338.2	6.2E-101	17	269	253

Status

Unreviewed

Ensembl Protein

ENSTRUP00000047212

UniProt Accession

H2VDB6;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA1

Gene Synonyms/Alias

PRKAA1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTRUG00000018441	ENSTRUP00000047210	ENSTRUT00000047369
ENSTRUG00000018441	ENSTRUP00000047211	ENSTRUT00000047370
ENSTRUG00000018441	ENSTRUP00000047212	ENSTRUT00000047371

Organism

Takifugu rubripes

Functional Description

Protein Length

559

Protein Sequence
(FASTA)

MATEKNKHEG RVKIGHYILG DTLGVGTFGK VKVGQHELTK HQVAVKILNR QKIRSLDVVG 60

KIRREIQNLK LFRHPHIIKL YQVISTPTDI FMVMEYVSGG ELFDYICKNG KLDEKESRRL 120

FQQIISAVDY CHRHMVVHRD LKPENVLLDA HMNAKIADFG LSNMMSDGEF LRTSCGSPNY 180

AAPEVISGRL YAGPEVDIWS SGVILYALLC GTLPFDDDHV PTLFKKICDG IFFTPQYLNP 240

SVISLLKHML QVDPMKRATI REIREDEWFK QDLPKYLFPE DPSYSNNMID DEALKEVCEK 300

FECTEEEVLA CIYSRNHQDP LAVAYHLIID NRRIMNEAKD FYLASSPPDS FLDDQHMTTS 360

GVVTGVVKPH PERVPFLVAE TLPRPRHKLD ELNPQKSKHQ GVRRAKWHLG IRSQSRPNDI 420

MSEVCRAMKQ LDYEWKVVNP YYLRVRRKNP ITGMQTKMSL QLYQVDSRTY LLDFRSIDDD 480

MLEAKSGTAT PLRSGSVGNY RTAVNLVHSA KATEGSLASS LTSSTDSTGG ADNASVARPG 540

SHTIEFFEMC ANLIKLLAR 559

Nucleotide Sequence
(FASTA)

ATGGCGACGG AAAAAAACAA GCATGAAGGA AGAGTTAAAA TCGGGCATTA CATTCTCGGA 60

GACACGCTCG GAGTCGGGAC GTTCGGAAAG GTTAAAGTGG GCCAACATGA GCTAACTAAG 120

CACCAAGTAG CAGTGAAGAT CTTGAACCGG CAGAAGATCC GCAGTTTAGA TGTGGTGGGG 180

AAGATCCGCA GGGAGATACA GAACCTCAAG CTTTTTCGGC ATCCTCACAT AATTAAACTG 240

TATCAGGTAA TTAGCACCCC TACTGATATC TTCATGGTGA TGGAGTATGT CTCAGGAGGC 300

GAGCTTTTTG ATTACATCTG CAAAAATGGA AAGTTGGATG AGAAAGAGAG CCGTCGGCTG 360

TTCCAGCAGA TTATTTCCGC TGTAGACTAC TGCCACAGAC ACATGGTGGT ACACCGAGAC 420

CTCAAGCCTG AAAACGTGCT GCTCGATGCA CATATGAACG CCAAAATTGC AGACTTCGGT 480

TTGTCAAACA TGATGTCGGA CGGAGAGTTC TTGCGCACAA GCTGCGGTTC TCCAAACTAC 540

GCCGCGCCCG AGGTTATCTC AGGAAGGTTA TATGCTGGTC CAGAGGTGGA CATCTGGAGC 600

AGTGGGGTCA TTCTTTACGC CCTGCTGTGC GGGACGCTTC CGTTTGACGA CGACCACGTG 660

CCAACCCTGT TCAAGAAGAT CTGCGATGGG ATTTTTTTCA CTCCACAGTA TCTGAACCCT 720

TCAGTGATCA GCCTCCTCAA ACACATGCTG CAGGTGGATC CCATGAAGAG AGCCACCATT 780

AGAGAGATCC GAGAGGACGA GTGGTTCAAA CAGGACCTCC CCAAATACCT GTTCCCTGAA 840

GACCCCTCTT ACAGCAACAA CATGATCGAC GACGAGGCCC TAAAGGAGGT GTGTGAGAAG 900

TTTGAGTGCA CGGAGGAGGA GGTCCTGGCC TGCATCTACA GTCGCAACCA TCAGGACCCG 960

CTGGCCGTCG CATACCACCT CATCATCGAC AATCGTCGCA TCATGAACGA AGCCAAGGAC 1020

TTCTACCTGG CATCCAGCCC TCCTGACTCC TTCCTCGACG ACCAGCACAT GACCACATCT 1080

GGAGTGGTCA CCGGCGTCGT CAAACCCCAC CCCGAGCGCG TCCCCTTCCT GGTGGCAGAG 1140

ACGCTCCCCA GGCCTCGGCA CAAATTGGAC GAACTGAACC CCCAGAAGTC AAAGCACCAG 1200

GGTGTTAGAA GGGCCAAGTG GCACCTGGGG ATCCGCAGCC AGAGCAGGCC CAACGATATC 1260

ATGTCAGAAG TGTGTCGCGC CATGAAGCAG TTGGACTACG AGTGGAAGGT TGTGAATCCA 1320

TATTATCTGC GCGTCAGAAG GAAGAATCCC ATCACTGGCA TGCAGACTAA GATGAGCCTC 1380

CAGCTCTACC AGGTGGACAG TAGAACTTAC CTCCTCGACT TCCGTAGCAT AGACGATGAC 1440

ATGTTGGAAG CAAAATCTGG CACTGCTACG CCGCTGCGCT CTGGCTCTGT CGGCAACTAT 1500

CGCACCGCTG TTAACCTGGT GCACTCGGCC AAGGCCACAG AAGGCTCCCT AGCGTCATCA 1560

CTGACTTCAT CCACTGACTC AACGGGAGGC GCTGACAACG CATCAGTGGC ACGACCCGGA 1620

AGCCACACCA TTGAGTTCTT CGAGATGTGC GCAAATCTCA TTAAACTACT TGCACGATAG 1680

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y l++tlG g+fgkVk+ +h++tk++vavKi++++k+ s + + ki+rEi+ lk ++hp+

Q: 17    YILGDTLGVGTFGKVKVGQHELTKHQVAVKILNRQKIrSLDVVGKIRREIQNLKLFRHPH  76

         8899********************************96667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         iikl++vi+t +++++v+ey+sggeLfdyi ++g+l+eke+r+lf+q++sav+Y+h++ +

Q: 77    IIKLYQVISTPTDIFMVMEYVSGGELFDYICKNGKLDEKESRRLFQQIISAVDYCHRHMV  136

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+v

Q: 137   VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV  196

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+Ws Gv+Lyal++g+lPfd++++ +l++ki +g + +p++l+++++sLl+++L+vdp k

Q: 197   DIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFFTPQYLNPSVISLLKHMLQVDPMK  256

         ************************************************************

S: 240   Ratieeilkhewl  252

         Rati+ei+++ew+

Q: 257   RATIREIREDEWF  269

         ************7

Domain Sequence
(FASTA)

YILGDTLGVG TFGKVKVGQH ELTKHQVAVK ILNRQKIRSL DVVGKIRREI QNLKLFRHPH 60

IIKLYQVIST PTDIFMVMEY VSGGELFDYI CKNGKLDEKE SRRLFQQIIS AVDYCHRHMV 120

VHRDLKPENV LLDAHMNAKI ADFGLSNMMS DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV 180

DIWSSGVILY ALLCGTLPFD DDHVPTLFKK ICDGIFFTPQ YLNPSVISLL KHMLQVDPMK 240

RATIREIRED EWF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013