EKS-TUT-00120

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-TUT-00120

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	396.1	7.4E-119	211	515	305

Status

Unreviewed

Ensembl Protein

ENSTTRP00000004352

Gene Name

IRAK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTTRG00000004575	ENSTTRP00000004352	ENSTTRT00000004619

Organism

Tursiops truncatus

Protein Length

708

Protein Sequence
(FASTA)

MAGGPGPGDP AVPGAQHFLY EVPPWVMCRF YKVMDALEPA DWCQFAALIV RDQTELRLCE 60

RSGQRTASVL WPWINRNARV ADLVRILTHL QLLRARDIIT AWHPPAPLLP PSATAPRPNS 120

ISAPSEAAAP SPQKLHSSAS TLLSPALPGS QTHSDPELGP VPSPAALQPP LPSAAPSCIK 180

RSPESPASIL QGAHSSFCWP LHEICQGTHD FSEELKIGEG GFGCVYRAVM RNTVYAVKRL 240

KEDLEWTTVK QSFRTEVEQL SRFRHPNIVD FAGYCAQSGF YCLVYGFLPN GSLEDRLHVQ 300

TQTWPPLSWP QRLDILLGTA RAIQFLHQDS PSLIHGDVKS SNVLLDERLM PKLGDFGLAR 360

LSRFAGANPS RSSTVAQTRT VRGTLAYLPE EYIKTGRLAV ETDTFSFGVV VLETLTGQRA 420

VRMHGAQTKY LKDLVEEEAE EAGLALKSTQ TTLQAGLAAD AWAAPIATQI YKKHLDPRPG 480

PCPPELGLAL GQLACCCLHR RAKRRPAMTQ AYQKLETLQA AVAGPSLEPE ATSRSPPSPQ 540

ENSYVSTTGS TLSGASPWQP LAAPSGALAQ APERLQKGAN QPVESDESMS GLSAALHSWH 600

LTPSCPPGPA PLGQAGCTQG DATRQSSWGS SPGLQPTAVE GPLLGGSTSP LPPQIVINPA 660

RQKMLQKLAL YEDGVLDSLQ LLSSSSLPDL GLEHGNRQGP EESDEFQS 708

Nucleotide Sequence
(FASTA)

ATGGCCGGGG GGCCGGGCCC GGGAGACCCC GCGGTCCCCG GCGCCCAGCA CTTCCTGTAC 60

GAGGTGCCGC CCTGGGTCAT GTGCCGCTTC TACAAAGTGA TGGACGCCCT GGAGCCCGCC 120

GACTGGTGCC AGTTCGCCGC CCTGATCGTA CGCGACCAGA CCGAGCTGCG GCTATGCGAG 180

CGCTCCGGGC AGCGCACGGC CAGCGTCCTG TGGCCCTGGA TCAACCGCAA CGCCCGCGTG 240

GCCGACCTCG TGCGCATCCT CACGCACCTG CAGCTGCTCC GCGCGCGGGA CATCATCACG 300

GCATGGCACC CTCCCGCCCC GCTTCTGCCC CCCAGCGCCA CCGCCCCGAG GCCTAACAGC 360

ATCTCTGCAC CTTCTGAGGC CGCGGCCCCC AGCCCCCAGA AGTTGCACTC GTCGGCCTCC 420

ACCCTCCTCT CCCCAGCTCT TCCAGGCTCC CAGACTCATT CTGACCCTGA GCTCGGCCCT 480

GTCCCAAGCC CTGCTGCCCT CCAGCCACCA CTGCCATCGG CAGCCCCTTC CTGTATCAAG 540

CGGAGCCCAG AGAGCCCAGC GTCCATCCTG CAGGGGGCCC ACTCCTCTTT CTGCTGGCCC 600

CTCCATGAGA TTTGCCAGGG CACCCACGAC TTCTCAGAGG AGCTGAAGAT CGGGGAGGGC 660

GGCTTTGGGT GTGTGTACCG GGCTGTGATG AGGAACACGG TATATGCTGT GAAGAGGCTA 720

AAGGAGGACC TGGAGTGGAC CACGGTGAAG CAGAGCTTTC GGACCGAAGT GGAGCAGCTG 780

TCACGGTTTC GTCACCCGAA CATCGTGGAC TTTGCTGGCT ACTGTGCTCA GAGTGGCTTC 840

TACTGCCTTG TCTATGGCTT CCTGCCCAAC GGCTCCCTGG AAGACCGCCT CCATGTCCAG 900

ACCCAGACCT GGCCTCCTCT CTCCTGGCCT CAGCGACTGG ACATCCTTCT GGGCACGGCC 960

CGGGCAATTC AGTTTTTACA TCAAGACAGC CCCAGCCTCA TCCACGGAGA TGTCAAGAGT 1020

TCCAACGTCC TTCTGGATGA GAGACTGATG CCCAAACTGG GAGACTTCGG CCTGGCCCGT 1080

CTCAGCCGGT TTGCAGGCGC CAACCCCAGC CGGAGCAGCA CTGTGGCCCA GACTCGGACT 1140

GTGCGTGGCA CCCTGGCGTA CCTGCCCGAG GAGTACATCA AGACGGGGAG GCTGGCTGTG 1200

GAGACCGACA CCTTCAGTTT CGGCGTGGTG GTGCTGGAGA CCCTGACCGG CCAGCGGGCT 1260

GTGAGGATGC ACGGTGCCCA GACCAAGTAT CTGAAAGACC TGGTTGAAGA GGAAGCCGAG 1320

GAGGCTGGTT TGGCCCTGAA AAGCACCCAG ACCACACTCC AAGCAGGTCT GGCTGCAGAT 1380

GCCTGGGCCG CCCCGATCGC CACCCAGATC TACAAGAAGC ACCTGGACCC CAGGCCTGGG 1440

CCGTGCCCAC CAGAGCTGGG CCTGGCCCTG GGCCAGCTGG CTTGCTGCTG CCTGCACCGC 1500

CGGGCCAAGA GGAGACCCGC CATGACCCAG GCGTACCAGA AGCTGGAGAC GCTGCAGGCG 1560

GCAGTGGCAG GGCCGTCTCT GGAGCCAGAG GCCACCAGCC GCAGCCCCCC TTCCCCTCAG 1620

GAGAACTCCT ACGTGTCCAC CACTGGCAGT ACCCTGAGCG GTGCCAGCCC ATGGCAGCCC 1680

CTGGCGGCGC CCTCGGGAGC CCTGGCCCAG GCTCCAGAGC GGCTGCAGAA AGGCGCCAAC 1740

CAGCCCGTGG AGAGCGACGA GAGCATGTCC GGCCTATCTG CTGCCCTGCA TTCCTGGCAC 1800

CTGACCCCGA GCTGCCCCCC GGGCCCAGCA CCCCTCGGAC AGGCTGGCTG TACTCAAGGG 1860

GATGCCACCA GACAGTCGAG CTGGGGGAGC AGCCCGGGGC TCCAGCCCAC AGCTGTGGAA 1920

GGACCGCTCC TGGGCGGCTC CACGTCGCCA CTACCCCCCC AGATTGTCAT CAACCCGGCG 1980

CGACAGAAGA TGCTGCAGAA GCTGGCCTTG TACGAGGATG GGGTCCTAGA CAGCCTGCAG 2040

CTGCTGTCAT CTAGCTCCCT CCCAGACTTG GGCCTGGAGC ACGGGAACAG GCAGGGGCCC 2100

GAAGAGAGTG ATGAGTTTCA GAGCTGA 2127

Domain Profile

S: 1     fsednrigeGgfgevyrgelkntavavkklkeeadlslkelkqsfltElkvlarfrHdni  60

         fse+ +igeGgfg+vyr+ ++nt++avk+lke  dl+++++kqsf tE+++l+rfrH+ni

Q: 211   FSEELKIGEGGFGCVYRAVMRNTVYAVKRLKE--DLEWTTVKQSFRTEVEQLSRFRHPNI  268

         899***************************97..789***********************

S: 61    lellgysaeseklcLvYqymknGsLedrLqcq.kgsepLsWpqRlsillGtaraiefLHe  119

         ++++gy+a+s+++cLvY++++nGsLedrL++q +  +pLsWpqRl+illGtarai+fLH+

Q: 269   VDFAGYCAQSGFYCLVYGFLPNGSLEDRLHVQtQTWPPLSWPQRLDILLGTARAIQFLHQ  328

         ********************************77889***********************

S: 120   aspslihgdiksaNiLLDekltpKlgDfglar...fapesekqsstvlrtskvrgtlaYl  176

         +spslihgd+ks+N+LLDe+l+pKlgDfglar   fa+++++ sstv++t +vrgtlaYl

Q: 329   DSPSLIHGDVKSSNVLLDERLMPKLGDFGLARlsrFAGANPSRSSTVAQTRTVRGTLAYL  388

         *******************************99999************************

S: 177   peefirvgqltvkvDvySfGiVllEvltGlra.vdedrktkyLkdllkeeieeekv....  231

         pee+i++g+l+v++D++SfG+V+lE+ltG+ra + ++++tkyLkdl++ee+ee+++

Q: 389   PEEYIKTGRLAVETDTFSFGVVVLETLTGQRAvRMHGAQTKYLKDLVEEEAEEAGLalks  448

         ********************************77899***********************

S: 232   ....................eilekfldkkagkleeellealielalaclaekakkrPtm  271

                             +i++k+ld ++g++++el  al +la++cl+++ak+rP m

Q: 449   tqttlqaglaadawaapiatQIYKKHLDPRPGPCPPELGLALGQLACCCLHRRAKRRPAM  508

         ************************************************************

S: 272   sqvlell  278

         +q +++l

Q: 509   TQAYQKL  515

         **99986

Domain Sequence
(FASTA)

FSEELKIGEG GFGCVYRAVM RNTVYAVKRL KEDLEWTTVK QSFRTEVEQL SRFRHPNIVD 60

FAGYCAQSGF YCLVYGFLPN GSLEDRLHVQ TQTWPPLSWP QRLDILLGTA RAIQFLHQDS 120

PSLIHGDVKS SNVLLDERLM PKLGDFGLAR LSRFAGANPS RSSTVAQTRT VRGTLAYLPE 180

EYIKTGRLAV ETDTFSFGVV VLETLTGQRA VRMHGAQTKY LKDLVEEEAE EAGLALKSTQ 240

TTLQAGLAAD AWAAPIATQI YKKHLDPRPG PCPPELGLAL GQLACCCLHR RAKRRPAMTQ 300

AYQKL 305

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>