EPS-TUT-00019

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-TUT-00019

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	205.3	1.1E-60	649	894	246

Status

Unreviewed

Ensembl Protein

ENSTTRP00000014502

Gene Name

PHLPP1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSTTRG00000015300	ENSTTRP00000014502	ENSTTRT00000015300

Organism

Tursiops truncatus

Protein Length

1192

Protein Sequence
(FASTA)

KPHSTGSSER IQLSGMYNVR KGKMQLPVNR WTRRQVILCG TCLIVSSVKD SFTGKMHVLP 60

LIGGKVEEVK KHQHCLAFSS SGPQSQTYYI CFDTFTEYLR WLRQVSKVAS QRISSVDLSC 120

CSLEHLPANL FYSQDLTHLN LKQNFLRQSP SLPTARGLNE LQRFSKLKCL NLSNNHLGDF 180

PLAVCNIPTL AELNVSCNAL RAVPAAVGDM HNLQTFLLDG NFLQTLPAEL ENMHQLSYLG 240

LSFNEFTDIP EVLEKLTAVE KLCMSGNCME TLRLQALRKM PHIKHVDLRL NLIRKLIADE 300

VDFLPHVTQL DLRDNKLRDL DAMVFNNIEV LHCERNQLVT LNICGYFLKA LYTSSNELVQ 360

LDVYPVPNYL SYMDVSRNRL ENVPEWVCES RKLEVLDIGH NQICELPARL FCNSSLRKLL 420

AGHNQLTRLP ERLERTSVEV LDVQHNQLLE LPPNLLMKAD SLRFLNASAN QLVNLPPATL 480

SEETNSVLQE LYLTINNLTY KCVPLLTGHP HLKILHIVYI RLLSFPASKM AKLEELEEID 540

ISGNKLKAVP TTIMNCRRMH TVIAHSNCIE VFPEVMQLPE IKCVDLSCNE LSEVTLPENL 600

PPKLQELDLT GNPRLALDHK TLELLNNIRC FKIDQPSGGD ASGAPAVWSH GYTEASGVKN 660

KLCVAALSVN NFRDNREALY GVFDGDRNVE VPYLLQCTMS DILAEELQKT KNEEEYMVNT 720

FIVMQRKLGT AGQKLGGAAV LCHIKHDPVD PGGPFTLTSA NVGKCQTVLC RNGKPLPLSR 780

SYVMSCEEEL KRIKRHKAII TEDGKVNGVT ESTRILGYTF LHPSVVPRPH VQSVALTPQD 840

EFFILGSKGL WDSLSVEEAV GAVRNVPDAL AAAKKLCTLA QSYGCRDSVS AVVVQLSVPE 900

DSFCCCELGA GGPVPPPSPG TFPPSVSMVI KERPADGLGV PSSSSGLASE MSSELSTSEM 960

SSEVGSTASD EPPPGALSES SPACPSEPRC SLHPACPSSS FQRQLSSATF SSAFSDNGLD 1020

SDDEEPIEGV FTNGSRVEVE VDIHCGRTKE KERQQPLLQL PAEASDEGIV ISANEDEPAL 1080

PRRADCAAVG TMGRRRANGS VAPQERSHNV IEVATDAPLR KPGGYFAAPA QPDPDDQFII 1140

PPELEEEVKE IMKHQQPPPP PPPPPPPSQL HVQPPPRQCP GDQLPDCCDT PL 1192

Nucleotide Sequence
(FASTA)

AAACCTCACA GCACTGGTAG CTCTGAACGG ATTCAGCTCT CAGGAATGTA TAATGTCCGT 60

AAAGGCAAAA TGCAGTTGCC AGTGAACCGA TGGACCAGAC GCCAAGTTAT CCTGTGTGGG 120

ACCTGCCTAA TAGTATCATC TGTGAAAGAC AGCTTCACCG GAAAGATGCA TGTTCTGCCA 180

CTAATTGGTG GGAAGGTAGA AGAAGTGAAA AAACACCAGC ACTGTTTAGC ATTTAGCTCC 240

TCTGGACCCC AAAGCCAGAC TTACTACATT TGTTTTGATA CATTCACAGA GTATTTAAGG 300

TGGCTTCGAC AAGTCTCCAA GGTTGCATCA CAGCGTATTA GCTCAGTGGA CCTCTCATGT 360

TGTAGCCTGG AGCATCTGCC TGCCAACCTC TTCTACAGCC AAGACCTCAC TCATCTCAAT 420

TTAAAACAAA ACTTCCTAAG GCAGAGTCCC AGTCTACCAA CTGCAAGGGG GCTCAATGAA 480

CTGCAAAGGT TCAGCAAGTT GAAGTGTCTT AACCTTTCCA ATAATCATTT AGGGGACTTC 540

CCATTAGCAG TCTGCAATAT TCCAACCCTG GCCGAGCTGA ATGTGTCCTG CAATGCCCTC 600

CGAGCAGTCC CGGCAGCCGT CGGAGATATG CACAACTTAC AGACATTTTT GTTGGATGGA 660

AACTTTCTCC AGACCCTTCC TGCTGAGTTG GAGAACATGC ATCAGCTTAG TTATCTTGGT 720

CTTTCTTTCA ATGAATTCAC TGACATTCCA GAGGTATTGG AGAAACTGAC TGCTGTGGAG 780

AAACTGTGCA TGTCTGGAAA CTGTATGGAG ACTCTTAGGC TACAGGCTTT AAGGAAAATG 840

CCTCACATTA AACATGTGGA TCTAAGACTG AACCTAATTA GGAAGCTAAT AGCAGATGAA 900

GTGGACTTTC TCCCTCACGT CACTCAGCTT GATCTGCGCG ACAATAAGCT TCGTGATCTA 960

GATGCTATGG TTTTCAACAA CATTGAAGTT TTACACTGTG AAAGGAATCA ACTGGTGACA 1020

TTAAACATCT GTGGCTATTT CCTGAAAGCA CTGTATACCT CTTCTAATGA ACTTGTCCAA 1080

CTTGACGTTT ACCCAGTTCC GAATTATCTG TCCTACATGG ATGTTTCAAG GAACCGTTTA 1140

GAAAACGTGC CTGAGTGGGT GTGTGAAAGC CGAAAGCTAG AAGTTTTGGA TATTGGCCAT 1200

AATCAAATAT GTGAACTTCC TGCACGCTTA TTTTGTAATA GTAGTCTCCG GAAACTACTG 1260

GCGGGACACA ACCAGCTGAC AAGGCTTCCC GAAAGGCTAG AAAGAACCTC AGTGGAGGTC 1320

TTGGATGTGC AGCACAACCA GCTCCTGGAG CTGCCACCCA ACCTTCTGAT GAAGGCCGAC 1380

AGCCTGAGAT TCCTGAATGC ATCTGCAAAC CAACTGGTAA ACCTTCCTCC AGCCACACTT 1440

TCTGAAGAGA CAAACAGCGT CTTACAGGAG TTGTATTTGA CGATCAACAA CCTCACATAT 1500

AAATGTGTAC CCTTGTTAAC AGGGCACCCC CATCTGAAGA TTCTTCACAT TGTCTATATC 1560

CGACTTCTGA GTTTTCCAGC AAGTAAAATG GCAAAGCTGG AAGAACTTGA AGAAATTGAC 1620

ATCAGTGGGA ATAAACTGAA GGCCGTCCCG ACAACGATCA TGAATTGCAG GCGCATGCAC 1680

ACGGTGATCG CTCACTCCAA CTGCATCGAG GTCTTTCCTG AAGTTATGCA GCTCCCAGAA 1740

ATCAAGTGCG TGGACCTGAG CTGTAATGAG CTAAGCGAAG TCACTTTACC AGAAAACCTG 1800

CCTCCAAAAC TGCAAGAACT AGACCTGACT GGAAACCCCC GACTCGCCCT CGATCACAAA 1860

ACCCTGGAGC TGCTGAATAA TATCCGCTGT TTCAAGATTG ATCAGCCTTC GGGAGGCGAT 1920

GCGTCTGGAG CCCCAGCTGT ATGGAGCCAT GGCTACACCG AAGCTTCAGG GGTGAAAAAC 1980

AAGTTGTGTG TTGCAGCCCT GTCGGTGAAT AACTTCCGTG ACAACCGGGA GGCCCTGTAT 2040

GGTGTATTTG ATGGAGACCG GAACGTGGAG GTGCCCTACC TTCTCCAGTG TACCATGAGT 2100

GACATTTTGG CAGAAGAGCT GCAGAAAACA AAAAACGAAG AAGAATACAT GGTCAATACG 2160

TTCATTGTTA TGCAAAGGAA GCTTGGAACT GCTGGGCAGA AACTTGGAGG TGCTGCTGTC 2220

CTTTGTCATA TCAAGCATGA CCCTGTGGAC CCAGGAGGAC CCTTCACCTT GACCTCTGCT 2280

AATGTGGGCA AGTGCCAAAC GGTTCTGTGT CGGAACGGGA AGCCGCTGCC TCTGTCCAGG 2340

TCATACGTTA TGAGCTGTGA GGAAGAACTG AAGAGAATCA AACGGCACAA GGCCATTATC 2400

ACGGAGGATG GCAAAGTGAA CGGAGTGACC GAGTCCACGC GCATCCTGGG CTACACGTTC 2460

CTGCACCCCA GCGTGGTGCC CCGCCCCCAT GTGCAGTCCG TGGCCCTGAC CCCGCAGGAC 2520

GAGTTCTTCA TCCTGGGCAG CAAGGGCCTG TGGGACAGCC TGTCTGTTGA GGAGGCCGTG 2580

GGGGCCGTGC GCAACGTCCC CGACGCTCTG GCCGCCGCCA AGAAGCTGTG CACGCTGGCG 2640

CAGAGCTACG GCTGCCGCGA CAGCGTCAGC GCCGTGGTGG TGCAGCTCAG CGTCCCCGAG 2700

GACAGCTTCT GCTGCTGCGA GCTCGGCGCC GGCGGGCCCG TGCCGCCGCC CAGCCCCGGC 2760

ACCTTCCCGC CCTCCGTCAG CATGGTCATC AAGGAGCGGC CCGCCGACGG GCTGGGCGTG 2820

CCGTCGTCCA GCAGCGGCCT GGCCTCGGAG ATGAGCAGCG AGCTCTCCAC GTCCGAGATG 2880

AGCAGCGAGG TGGGGTCCAC GGCCTCGGAC GAGCCCCCTC CGGGCGCCCT GAGCGAGAGC 2940

AGTCCCGCCT GCCCCAGCGA GCCGCGCTGC TCGCTGCACC CCGCCTGCCC GTCCAGCTCC 3000

TTCCAGCGCC AGCTGTCCAG CGCCACTTTC TCTAGCGCCT TCTCCGACAA CGGCCTCGAC 3060

AGCGATGACG AAGAGCCCAT CGAGGGCGTC TTCACCAACG GCAGCCGGGT GGAGGTGGAG 3120

GTGGACATCC ACTGCGGCCG CACCAAGGAG AAGGAGAGGC AGCAGCCCCT GCTGCAGCTG 3180

CCGGCCGAGG CCAGCGACGA GGGTATCGTC ATCAGCGCCA ACGAGGACGA GCCGGCCCTG 3240

CCCCGGAGGG CGGACTGTGC CGCCGTGGGG ACCATGGGGC GCCGGAGGGC TAACGGCTCC 3300

GTGGCGCCCC AGGAACGGAG CCACAACGTG ATAGAGGTGG CCACGGACGC GCCTCTCCGC 3360

AAGCCGGGGG GCTATTTTGC AGCCCCGGCT CAGCCAGATC CTGATGATCA GTTCATCATT 3420

CCCCCGGAGC TGGAGGAGGA GGTCAAAGAG ATCATGAAAC ACCAGCAGCC GCCACCGCCG 3480

CCGCCGCCAC CGCCGCCGCC CTCACAGCTC CACGTGCAGC CGCCGCCGCG GCAGTGCCCG 3540

GGGGACCAGC TGCCAGACTG CTGTGACACA CCGCTATGA 3579

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf +++e+     ++gv+DG+++ ev + +++++++il

Q: 649   SHGYTEASGVKNKLCVAALSVNNFRDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  703

         689**********************99775.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    ++++ ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 704   AEELQ----KTKNEEEYMVNTFIVMQRKL------GTAGQKLGGAAVLCHIKHDpvdpgg  753

         ***99....999*****************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls+ + +s+e+El+Ri+++++ ++++   +v+Gv++

Q: 754   pfTLTSANVGKCQTVLCRNGKPLPLSRSYVMSCEEELKRIKRHKAIITEDG--KVNGVTE  811

         ********************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s+ lt++def+iL+s+Glwd +s eeav +vr+v +

Q: 812   STRILGYTFLHPSVVPRPHVQSVALTPQDEFFILGSKGLWDSLSVEEAVGAVRNVPD---  868

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +aakkL++la+++g++d+vsa+vv

Q: 869   -ALAAAKKLCTLAQSYGCRDSVSAVVV  894

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS VNNFRDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKNEEEYMV NTFIVMQRKL GTAGQKLGGA AVLCHIKHDP VDPGGPFTLT SANVGKCQTV 120

LCRNGKPLPL SRSYVMSCEE ELKRIKRHKA IITEDGKVNG VTESTRILGY TFLHPSVVPR 180

PHVQSVALTP QDEFFILGSK GLWDSLSVEE AVGAVRNVPD ALAAAKKLCT LAQSYGCRDS 240

VSAVVV 246

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>