EKS-XET-00083

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00083

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	441.9	1.8E-132	2298	2624	327

Status

Unreviewed

Ensembl Protein

ENSXETP00000001341

UniProt Accession

F7DU67;

Protein Name

Protein Synonyms/Alias

Gene Name

atr

Gene Synonyms/Alias

atr;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000000617	ENSXETP00000001341	ENSXETT00000001341

Organism

Xenopus tropicalis

Functional Description

Protein Length

2649

Protein Sequence
(FASTA)

MAADPGLEMA SMIPALRELA SAEADEYNTI VQKPRQILCQ FIDRILTDVD VVAVELSKNT 60

DSQPSSVMLL DFIQHIMKSS PLMFLSANNV DQSAETNQNC VAFSNWIISR VLRIGATPSC 120

KALHRKIAEV IRSLLFLFKN KSPFLFGVLT KDLLHLFEDL ICIHEQNMEQ SIVWPVTVSR 180

FLSNASENQA YLRCAPFQLL NMQCIEPLES TLLMVLMDNE NDIFPVFFQR QNLLLWGIGC 240

SLLDYGTTPL KIQALHFLRE LIKLGGPPEQ GAYFFFIVFF GILTYIKDMD LEELSLYEMP 300

LLELVRVLFI FESKSYLSIE PVYLNMLLEK LAALFKAGIL KNIQSAPLKE ALCYMVHYFL 360

SVVPPGYESA KEVREVHVRC ICSAFVDVLG LQSKQEYLVF PLHEALRVES LAYMQQQSMQ 420

PLSTDSEGGG SSSSDEVQEK RPRLSLTAKP LRRNIPSTPA PVDMKTKSML WKAVSAKLSS 480

LLCKLEGDEV SEEEMVSLLE GVNTTICVAA LSIVHIFAKN STHIYNVLQN NNTYKRKCSI 540

CRVSWVSPED ILKILKICRK ILDSAHQRAS INDILMKIIK IFDAILYIHA GTRLNDETLK 600

DLCAMISLPW FQNHSNHASF KVASFDPALV TLSEQISQHF SPEIQSQLVF LLCLFPKMLC 660

PEWRLAVYHW ALDSQHEIVR ARCIKGFPVL LCNISQQGYG PIPKILIERL NDASELVKRE 720

LANAVGMFAS GLASGIELQY SPMAPTAAAS DFLCSSLRVT ALPSSEQSRM TASTLKPFLA 780

LLDRNMPSSV KMAFIENMPM LFDHLSFEKD DIDSRTVIES LLNLMEDPDQ DVRIAFSGNI 840

RYLLTCAEYE EGYLKEILVS RMKKAYTNAK MSRDNEMKDT LILTTGDIGR AAKGELVPFA 900

LLHLLHCLLS KSTSVAGASY TEIRSLAAAK STSLQIFFSQ YKKPICQFLV ESLHSSQAAL 960

LTNTPGRSSE MQKQEAAHHR EAALDILSEI ANVFDFPDLN RFLTITFYEL IPEREHQFIK 1020

FAKQNALKTM DLAKSFACHT ILLSYFKISS GIKGDRANAS LYLKYENETE IELGSLLRQD 1080

YQGLHNELLL RLGEHYQQVF NGLSILASFA SSDDPYQGPR TITKQEIMAD YLQPKLLGIL 1140

AFFNMHLLSS SIGIEDKKMA LNSLVFLMKL MGLKHISSVR VKMMTTLRTG LRYKEEFPEL 1200

CCSAWDLFVR CLDPAYLGSL LSHVIVALLP LLHIQPKETV AVFRYLIVEN RVAVQDFLHE 1260

IYFLPDHPEL KEIQKVLQEY RKETTKSTDL QTAMQLSIRA IQHENVDVRM HALTSLKETL 1320

YKNQAKLLQY STDSETVEPV ISQLVTVLLI GCQDANPQAR LFCGECLGQL GAIDPGRLDF 1380

SASETQGTRG FTFVSGVEDS DFAYELLTEL TRAFLAYADN VRAQDSAAYA IQELLSIYEC 1440

KEGRTDCPGR RLWKRFPEHV QEILEPHLNT RYKSSKKAVN WSRVKKPIYL SKLGNNFADW 1500

SATWAGYLIT KVRHEFARRV FGCCSIMMKH DFKVTIYLLP HILVYVLLGC NKEDQQEVYA 1560

EIMAVLKHED PLMRRLQDSA SDVSQLSTQT VFSMLDHLTQ WAREKFQALN AEKTNTKPGH 1620

RGELKAVSNE DYGEYQNVTR FLDLIPQDTL AVASFRSKAY TRAVMHFESF IMEKKQEIQE 1680

HLGFLQKLYA AMHEPDGVAG VSAIRKKEAS LKEQILEHES IGLLRDATAC YDRAIQLKPE 1740

EIIHYHGVVK SMLGLGQLST VITQVNGVLN SRPEWTAELN TYRVEAAWKL SQWDLVGDYL 1800

SADRKSTTWS IRLGQLLLAA KKGESDRFYE TLKVVRAEQI VPLSAASFER GSYQRGYEYI 1860

VRLHMLCELE HSVKMFLQKS SVEPPVDSLN LPARLEMTQN SYRAREPILA LRRALQTINK 1920

RPNDADIIGE CWLQSARVAR KAGHHQAAYN ALLNAGESRL SELNVERAKW LWSKGDVHQA 1980

LIVLQKGAEL FLSNTIAPPE QQLIHGRAML LVGRLMEETA NFESNAVMKK YKDVTTLLPE 2040

WEDGHFYLAK YYDKLMPMVT DNKMEKQGDL IRYIVLHFGR SLQFGNQYIY QSMPRMLSLW 2100

LDFGAKVYEW EKAGRADRLQ MKNELIKINK VISDHKNQLA PYQFLTAFSQ LISRICHSHD 2160

EVFAVLMEIV AKVFVAYPQQ AMWMMTAVSK SSYPMRVNRC KEILNKAIHM KPSLGKFIGD 2220

ATRLTDKLLE LCNKPVDGNT SILSMNIHFR MLKKLVEELT FSEILIPLQS VMIPTLPSTA 2280

GKRDHADHDP FPGHWAYIAG FDDAVEILPS LQKPKKISLK GSDGKSYIMM CKPKDDLRKD 2340

CRLMEFNSLI NKCLRKDAES RRRELHIRTY AVIPLNDECG IIEWVNNTAG FRNILIKLYK 2400

EKGIYMGGKE LRQCMLPKGA PLQEKLKVFK EALLPRHPPL FHEWFLRTFP DPTSWYNSRS 2460

AYCRSTAVMS MVGYILGLGD RHGENILFDS LTGECVHVDF NCLFNKGETF EVPEIVPFRL 2520

THNMVNGMGP MGTEGLFRRA CEVTMRLMRD QREPLMSVLK PFLHDPLVEW SKPARGGSKG 2580

QVNETGEVVN EKAKTHVLDI EQRLQGVIKT RNRVKGLPLS IEGHVHYLIQ EATDENLLSQ 2640

MYLGWAPYM 2649

Nucleotide Sequence
(FASTA)

ATGGCTGCTG ACCCCGGCCT CGAAATGGCC TCCATGATCC CGGCCTTGCG GGAACTTGCC 60

AGTGCGGAGG CAGATGAATA TAACACTATT GTTCAGAAAC CAAGACAAAT CCTTTGCCAG 120

TTTATAGACC GGATTCTGAC AGATGTGGAC GTTGTTGCTG TGGAGCTGTC AAAGAATACT 180

GATTCTCAGC CAAGTTCTGT AATGTTGCTG GATTTTATTC AACACATTAT GAAATCTTCA 240

CCATTAATGT TTCTCAGTGC AAATAATGTT GATCAGTCTG CCGAAACCAA TCAGAACTGT 300

GTTGCATTTA GCAACTGGAT CATTTCCCGG GTCCTACGCA TTGGGGCTAC ACCAAGCTGC 360

AAAGCTTTGC ATAGAAAAAT TGCTGAAGTC ATCCGCTCCC TGCTTTTTCT TTTCAAGAAC 420

AAGAGTCCTT TCCTATTTGG TGTTCTTACA AAAGATTTAT TACATCTTTT TGAAGATCTT 480

ATCTGCATAC ATGAACAGAA CATGGAGCAA TCCATAGTTT GGCCTGTGAC CGTCTCTAGA 540

TTTCTAAGCA ATGCATCAGA GAACCAAGCT TATTTGCGAT GCGCTCCATT TCAACTATTA 600

AACATGCAGT GCATTGAGCC TTTAGAATCC ACTCTGCTAA TGGTTTTGAT GGATAATGAA 660

AATGATATCT TTCCGGTGTT TTTCCAAAGG CAGAACCTCC TTCTTTGGGG CATCGGGTGC 720

TCTCTCTTGG ACTATGGAAC TACACCACTT AAGATACAAG CGTTACATTT TTTAAGAGAA 780

CTAATAAAAT TAGGGGGTCC ACCAGAACAG GGTGCATATT TTTTCTTTAT TGTTTTTTTT 840

GGGATACTAA CTTATATAAA AGACATGGAT TTAGAAGAAC TGTCTCTCTA TGAGATGCCA 900

CTTTTAGAAT TAGTAAGGGT TTTGTTCATA TTTGAATCTA AATCTTACCT AAGCATTGAA 960

CCTGTCTATC TAAACATGTT GCTGGAAAAA CTTGCTGCTC TCTTTAAAGC AGGTATCCTG 1020

AAGAATATTC AGTCAGCTCC CCTAAAAGAA GCTCTTTGCT ATATGGTCCA TTATTTCCTT 1080

AGTGTTGTAC CTCCAGGCTA TGAATCTGCC AAAGAAGTTC GTGAGGTACA TGTTCGCTGC 1140

ATCTGTAGTG CTTTTGTTGA TGTCCTTGGA CTTCAGAGCA AACAAGAATA CTTGGTTTTC 1200

CCCCTTCATG AAGCATTAAG AGTAGAAAGT TTGGCATACA TGCAGCAGCA AAGCATGCAG 1260

CCCTTAAGCA CAGACTCAGA GGGTGGTGGG AGCAGCAGCA GCGATGAAGT TCAGGAGAAG 1320

CGACCACGTC TAAGCCTAAC TGCAAAACCC CTGAGGAGGA ACATACCATC AACACCTGCA 1380

CCTGTGGATA TGAAGACAAA GAGCATGCTT TGGAAAGCAG TGAGTGCAAA ACTCTCCTCT 1440

CTTTTATGCA AATTGGAAGG CGATGAGGTT TCAGAAGAAG AGATGGTTTC TTTATTGGAG 1500

GGTGTCAATA CAACTATATG TGTTGCTGCT CTCAGTATAG TTCATATCTT CGCTAAAAAT 1560

TCAACACATA TTTATAATGT TTTACAGAAT AATAATACAT ACAAACGTAA ATGTTCTATC 1620

TGCAGGGTTT CCTGGGTCAG TCCAGAGGAT ATACTAAAAA TACTTAAAAT TTGCAGAAAG 1680

ATTCTTGATT CTGCACACCA GCGAGCCAGT ATAAATGACA TTCTGATGAA GATAATCAAA 1740

ATATTTGATG CAATACTCTA CATTCATGCA GGAACTAGGT TAAATGACGA AACGCTTAAA 1800

GATTTGTGTG CCATGATCTC ATTACCCTGG TTTCAGAATC ACTCAAATCA TGCTTCGTTT 1860

AAAGTGGCAT CATTTGACCC AGCGTTGGTG ACATTAAGTG AGCAGATCAG CCAACATTTC 1920

TCACCTGAAA TTCAGTCTCA GCTTGTTTTC CTCCTGTGCC TGTTTCCAAA AATGTTATGC 1980

CCTGAATGGA GATTAGCAGT GTACCACTGG GCATTGGATA GCCAACATGA GATTGTCCGT 2040

GCCCGCTGCA TCAAAGGATT CCCTGTTCTT CTGTGCAATA TTAGCCAGCA GGGGTATGGT 2100

CCAATTCCCA AGATTTTAAT TGAACGTTTG AATGATGCCT CTGAGTTGGT GAAGAGGGAG 2160

TTAGCCAATG CAGTGGGTAT GTTTGCCTCT GGCCTTGCTA GCGGTATTGA GCTGCAGTAT 2220

TCACCTATGG CACCTACAGC AGCAGCATCT GACTTCCTTT GTAGCAGCCT GAGAGTTACT 2280

GCTTTACCTT CATCTGAACA ATCTCGTATG ACCGCCTCTA CATTAAAACC ATTCCTGGCA 2340

CTGCTTGATC GAAACATGCC AAGCTCCGTC AAAATGGCAT TTATTGAAAA TATGCCGATG 2400

CTTTTTGATC ACCTCTCTTT TGAGAAAGAT GATATTGATT CCCGAACTGT AATTGAATCG 2460

TTGTTAAACC TAATGGAGGA TCCGGACCAG GATGTAAGGA TAGCTTTTAG TGGGAACATA 2520

AGATATCTGT TGACATGTGC AGAATATGAG GAAGGATATC TAAAGGAGAT TCTAGTCTCA 2580

AGGATGAAAA AAGCATACAC AAATGCCAAG ATGTCACGTG ATAATGAGAT GAAGGACACT 2640

CTAATTCTTA CAACTGGTGA TATAGGAAGG GCAGCAAAAG GAGAGTTGGT ACCATTTGCA 2700

TTGTTGCATC TGCTGCATTG CCTGCTATCA AAATCCACAT CTGTGGCAGG AGCATCTTAT 2760

ACAGAAATCC GATCTCTTGC AGCAGCAAAG TCCACCAGTC TGCAGATTTT TTTTAGCCAG 2820

TACAAGAAAC CAATTTGCCA GTTTCTTGTA GAATCGCTTC ATTCAAGCCA GGCAGCCCTT 2880

CTGACCAACA CACCTGGCCG AAGCAGTGAA ATGCAGAAGC AAGAGGCAGC ACATCATAGA 2940

GAAGCTGCAC TTGACATTTT ATCTGAAATA GCAAATGTAT TTGATTTCCC AGACTTAAAC 3000

CGCTTTTTAA CGATTACATT TTATGAGCTA ATCCCTGAGA GGGAACATCA GTTTATAAAA 3060

TTTGCAAAAC AAAACGCATT GAAGACAATG GACCTGGCAA AAAGTTTTGC TTGTCACACT 3120

ATACTGCTGT CCTATTTTAA AATAAGCTCT GGTATAAAAG GAGACAGAGC AAATGCATCC 3180

CTTTATCTCA AGTATGAGAA TGAAACCGAA ATTGAGTTGG GTAGTTTACT GAGACAGGAC 3240

TACCAGGGAC TGCACAATGA ACTACTCCTG CGCCTGGGAG AGCACTATCA GCAGGTCTTT 3300

AATGGGCTTT CTATATTAGC ATCATTCGCA TCCAGTGATG ATCCATATCA GGGACCTAGG 3360

ACCATCACAA AGCAAGAAAT AATGGCAGAT TATTTGCAAC CAAAGCTTTT AGGAATATTG 3420

GCTTTCTTCA ATATGCACCT GCTGAGTTCC AGTATTGGCA TTGAAGACAA AAAAATGGCC 3480

TTAAATAGTC TGGTATTTTT AATGAAACTG ATGGGTCTAA AGCATATAAG TTCCGTTAGG 3540

GTTAAGATGA TGACAACGTT AAGAACTGGC CTACGCTATA AAGAGGAATT TCCAGAACTC 3600

TGCTGCAGTG CATGGGACTT GTTTGTTCGC TGCTTGGATC CAGCGTATCT GGGCTCCCTC 3660

CTCAGTCATG TGATTGTTGC ATTGCTGCCT CTGTTGCACA TCCAGCCTAA AGAAACTGTT 3720

GCAGTGTTCC GCTATCTTAT AGTTGAGAAC AGGGTTGCTG TTCAGGATTT CCTTCATGAA 3780

ATTTATTTTC TACCTGATCA TCCAGAATTG AAAGAAATTC AGAAGGTTCT GCAAGAATAC 3840

AGGAAAGAAA CCACCAAAAG CACAGATTTG CAGACGGCCA TGCAACTGTC CATAAGAGCC 3900

ATCCAGCATG AAAATGTAGA TGTTCGCATG CATGCCCTTA CTAGTCTGAA AGAGACACTC 3960

TACAAGAACC AGGCTAAACT GCTGCAGTAT TCAACAGACA GTGAAACTGT CGAACCAGTT 4020

ATCTCACAGC TGGTAACAGT GCTGTTAATT GGCTGCCAAG ATGCCAATCC ACAAGCCCGT 4080

CTATTTTGTG GTGAATGCCT TGGCCAACTT GGAGCCATAG ATCCAGGGCG ATTGGATTTC 4140

TCAGCCAGTG AAACACAAGG GACAAGGGGC TTTACTTTTG TTTCAGGAGT TGAGGATTCA 4200

GATTTTGCCT ATGAACTGCT CACAGAGTTA ACAAGAGCAT TTCTTGCCTA TGCTGATAAT 4260

GTCCGTGCCC AGGACTCTGC TGCTTACGCC ATACAGGAGC TTCTCTCTAT TTATGAGTGC 4320

AAAGAAGGAA GGACTGATTG TCCTGGGCGT AGGCTCTGGA AGAGATTCCC AGAACATGTT 4380

CAAGAAATAT TGGAGCCACA TCTTAACACC AGATACAAGA GTTCCAAAAA GGCTGTAAAC 4440

TGGTCCAGAG TGAAAAAGCC CATTTATCTG AGCAAATTAG GCAATAACTT TGCAGACTGG 4500

TCAGCAACAT GGGCAGGTTA CCTCATAACT AAGGTTCGAC ATGAGTTCGC TAGGAGAGTT 4560

TTCGGCTGTT GTAGTATAAT GATGAAGCAT GACTTTAAAG TGACCATTTA CCTGCTCCCA 4620

CATATTCTGG TCTATGTGTT GTTAGGATGT AACAAAGAAG ATCAACAAGA GGTATATGCT 4680

GAAATCATGG CAGTCTTGAA GCATGAAGAT CCACTAATGC GTCGGTTACA GGACAGCGCC 4740

TCAGATGTGA GTCAGCTCAG TACCCAAACA GTCTTCTCCA TGCTTGATCA CCTTACTCAG 4800

TGGGCACGGG AAAAATTCCA GGCACTTAAT GCTGAGAAAA CAAACACCAA ACCAGGACAC 4860

AGAGGGGAAC TGAAGGCAGT ATCTAATGAA GACTATGGAG AGTATCAGAA TGTAACAAGG 4920

TTCTTAGATC TCATACCTCA GGATACTTTG GCTGTTGCTT CCTTTCGCTC CAAAGCTTAT 4980

ACCAGAGCTG TCATGCACTT TGAATCCTTT ATAATGGAGA AGAAACAAGA AATTCAGGAG 5040

CACCTTGGAT TTCTACAGAA ACTGTATGCT GCTATGCATG AGCCAGATGG AGTAGCTGGG 5100

GTAAGCGCCA TTCGCAAGAA AGAAGCTTCT CTGAAAGAAC AGATCTTGGA GCATGAAAGT 5160

ATTGGTTTGT TGAGAGATGC CACCGCTTGC TATGATAGAG CCATTCAGCT TAAACCTGAG 5220

GAGATAATTC ACTATCACGG GGTAGTGAAG TCTATGCTGG GTCTTGGCCA GTTGTCTACC 5280

GTAATTACTC AAGTTAACGG AGTGTTAAAT AGCAGGCCAG AGTGGACAGC TGAACTAAAC 5340

ACGTATAGAG TGGAAGCAGC ATGGAAACTC TCACAGTGGG ATTTAGTGGG GGATTACTTA 5400

TCTGCAGACA GAAAATCTAC CACATGGAGT ATTAGGCTGG GGCAGCTTCT GCTGGCAGCT 5460

AAAAAGGGAG AGAGCGATAG GTTTTATGAA ACACTCAAAG TTGTGCGAGC CGAACAAATT 5520

GTTCCACTGT CTGCTGCCAG CTTTGAAAGG GGCTCCTACC AACGAGGATA TGAGTACATA 5580

GTAAGGTTGC ACATGTTATG TGAGCTGGAA CATAGTGTAA AGATGTTTCT TCAGAAGTCT 5640

TCTGTTGAGC CCCCAGTAGA CTCTCTAAAC TTGCCAGCAC GGCTAGAAAT GACACAGAAT 5700

TCCTACAGAG CAAGAGAGCC CATCTTGGCA CTTCGCAGGG CATTGCAAAC AATCAACAAA 5760

AGGCCTAATG ATGCAGATAT CATTGGTGAG TGTTGGCTGC AAAGTGCCCG AGTTGCACGC 5820

AAGGCCGGAC ATCATCAGGC TGCTTACAAT GCACTACTTA ATGCTGGGGA GTCCAGACTG 5880

TCTGAGCTCA ACGTTGAAAG GGCAAAGTGG CTCTGGTCCA AGGGTGATGT ACATCAAGCT 5940

CTCATTGTTC TCCAGAAGGG AGCAGAACTG TTCCTGTCAA ATACCATCGC TCCACCAGAA 6000

CAGCAGCTTA TCCATGGCAG AGCCATGCTG CTGGTGGGCC GATTGATGGA AGAGACTGCC 6060

AACTTTGAAA GCAATGCTGT GATGAAGAAG TATAAAGATG TAACAACACT GTTGCCCGAA 6120

TGGGAAGATG GGCATTTTTA CCTTGCCAAG TACTATGACA AACTGATGCC AATGGTTACT 6180

GATAACAAAA TGGAGAAGCA AGGAGACTTG ATACGATATA TAGTACTTCA CTTTGGAAGG 6240

TCCTTACAGT TTGGAAACCA GTATATTTAT CAGTCGATGC CACGTATGCT TTCGCTTTGG 6300

CTGGATTTTG GAGCTAAGGT CTATGAATGG GAAAAAGCTG GTCGTGCGGA CAGATTGCAG 6360

ATGAAAAATG AATTAATCAA AATAAATAAG GTGATTTCTG ACCATAAAAA CCAACTTGCT 6420

CCTTATCAGT TCCTCACGGC TTTCTCACAG CTAATCTCCA GAATATGTCA CTCTCATGAT 6480

GAGGTGTTTG CCGTTTTGAT GGAAATTGTG GCAAAGGTAT TTGTGGCATA CCCTCAGCAG 6540

GCAATGTGGA TGATGACTGC TGTGTCTAAG TCGTCTTATC CAATGCGTGT AAACAGATGC 6600

AAAGAAATAC TCAATAAAGC CATACATATG AAGCCGTCCC TAGGAAAATT TATTGGAGAT 6660

GCAACTCGCC TCACTGATAA ACTGCTGGAG CTTTGCAATA AGCCGGTTGA TGGAAATACC 6720

AGCATCCTCA GTATGAATAT CCACTTCAGA ATGCTGAAGA AATTAGTAGA AGAACTAACA 6780

TTTAGTGAAA TCCTTATTCC TCTACAGTCA GTAATGATTC CCACCCTACC CTCTACTGCA 6840

GGAAAGCGCG ACCATGCTGA TCATGATCCG TTCCCTGGCC ACTGGGCTTA CATTGCAGGC 6900

TTTGATGACG CGGTAGAGAT ACTGCCTTCT CTCCAGAAAC CAAAGAAAAT TTCTCTAAAA 6960

GGTTCAGATG GGAAATCATA CATTATGATG TGTAAACCTA AAGATGATCT TAGAAAGGAT 7020

TGCCGGCTGA TGGAATTTAA CTCTTTAATC AACAAGTGTT TACGTAAAGA TGCCGAATCA 7080

CGAAGGAGAG AACTTCATAT ACGGACCTAT GCTGTCATTC CACTGAATGA TGAATGTGGA 7140

ATAATAGAGT GGGTGAATAA TACTGCAGGA TTCCGGAACA TATTGATCAA GCTGTACAAG 7200

GAAAAAGGTA TATACATGGG AGGAAAGGAA CTCCGGCAAT GTATGCTTCC CAAGGGAGCA 7260

CCGCTGCAAG AAAAGCTGAA AGTCTTTAAA GAGGCTCTGT TGCCTCGTCA CCCCCCTTTG 7320

TTCCATGAAT GGTTTTTAAG AACATTTCCT GATCCTACTT CTTGGTATAA CAGCAGATCA 7380

GCCTATTGCC GTTCTACTGC TGTGATGTCT ATGGTAGGTT ACATACTGGG CCTAGGGGAC 7440

CGCCATGGAG AGAACATTCT TTTTGACTCA CTTACTGGGG AATGTGTCCA TGTGGATTTC 7500

AACTGCCTCT TTAACAAGGG TGAAACATTT GAAGTTCCAG AGATTGTCCC CTTTCGCCTA 7560

ACTCATAACA TGGTCAATGG TATGGGCCCC ATGGGGACAG AAGGACTTTT TCGACGAGCA 7620

TGTGAAGTCA CTATGAGGTT AATGAGAGAC CAGAGGGAGC CACTTATGAG TGTGCTGAAA 7680

CCCTTCTTAC ATGATCCTTT GGTGGAATGG AGTAAACCAG CAAGAGGGGG AAGTAAAGGT 7740

CAAGTCAACG AGACCGGAGA AGTGGTGAAT GAAAAGGCCA AAACACATGT TCTTGACATA 7800

GAGCAGCGGC TACAAGGTGT AATTAAGACT AGGAATCGTG TAAAGGGACT TCCGCTCTCA 7860

ATTGAAGGAC ATGTCCATTA TCTGATCCAA GAAGCCACAG ATGAGAACCT TCTTAGCCAG 7920

ATGTACTTGG GGTGGGCACC GTATATGTGA 7950

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         iagfd+ veil+s+qkpkk++l+Gsdgk+y++++k+k+Dlr+d+r+++++sl+N++L+kd

Q: 2298  IAGFDDAVEILPSLQKPKKISLKGSDGKSYIMMCKPKDDLRKDCRLMEFNSLINKCLRKD  2357

         89**********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +e++rr+L+irty+V+pl++++g+iewv+nt++ +++l kl+++k++++          +

Q: 2358  AESRRRELHIRTYAVIPLNDECGIIEWVNNTAGFRNILIKLYKEKGIYMG--------GK  2409

         *************************************************6........99

S: 121   stvqarkpklkhlklslevfkevlenlvpkdllkklllekfpspeewfelrkaytrslAv  180

         + +q++ pk + l+++l+vfke+l +++p+ l+++++l++fp+p++w+++r+ay+rs+Av

Q: 2410  ELRQCMLPKGAPLQEKLKVFKEALLPRHPP-LFHEWFLRTFPDPTSWYNSRSAYCRSTAV  2468

         *****************************8.*****************************

S: 181   islvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrnivna  240

         +s+vgyiLgLgdrh en+l+d+ tge+vh+df++ f+k++t ++vpe+vPFRLT+n+vn+

Q: 2469  MSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGET-FEVPEIVPFRLTHNMVNG  2527

         *****************************************.******************

S: 241   lgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk.....kkktsketee  295

         +g++g+eG+fr++ce ++r++r+++e l+++L+ fl+dplv+w+k     +k++ +et+e

Q: 2528  MGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKPFLHDPLVEWSKparggSKGQVNETGE  2587

         ************************************************************

S: 296   elaekakaealkikkllskvekaenavatrdllllee  332

         +++ekak++ l+i+++l++v k++n+v+ ++l+++++

Q: 2588  VVNEKAKTHVLDIEQRLQGVIKTRNRVKGLPLSIEGH  2624

         ********************************99987

Domain Sequence
(FASTA)

IAGFDDAVEI LPSLQKPKKI SLKGSDGKSY IMMCKPKDDL RKDCRLMEFN SLINKCLRKD 60

AESRRRELHI RTYAVIPLND ECGIIEWVNN TAGFRNILIK LYKEKGIYMG GKELRQCMLP 120

KGAPLQEKLK VFKEALLPRH PPLFHEWFLR TFPDPTSWYN SRSAYCRSTA VMSMVGYILG 180

LGDRHGENIL FDSLTGECVH VDFNCLFNKG ETFEVPEIVP FRLTHNMVNG MGPMGTEGLF 240

RRACEVTMRL MRDQREPLMS VLKPFLHDPL VEWSKPARGG SKGQVNETGE VVNEKAKTHV 300

LDIEQRLQGV IKTRNRVKGL PLSIEGH 327

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR011990	; TPR-like_helical.
IPR012993	; UME.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08064	; UME; 1.

SMARTs

SM00146	; PI3Kc; 1.
SM00802	; UME; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013