EKS-XET-00230

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00230

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	469.1	5.5E-141	4	284	281

Status

Unreviewed

Ensembl Protein

ENSXETP00000060417

UniProt Accession

F6RS11;

Protein Name

Protein Synonyms/Alias

Gene Name

mak

Gene Synonyms/Alias

mak;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000001069	ENSXETP00000002325	ENSXETT00000002325
ENSXETG00000001069	ENSXETP00000060417	ENSXETT00000063967

Organism

Xenopus tropicalis

Functional Description

Protein Length

649

Protein Sequence
(FASTA)

MNRYTTMKQL GDGTYGSVLM GRSNESGELV AIKSLTNAFL CWKAPLTMQT QKSLKKLNHA 60

NVVKLKEVIR ENDQLFFVFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 120

FFHRDMKPEN LLCMGPELVK IADFGLVREL RSQPPYTDYV STRWYRAPEV LLRSSSYSSP 180

IDIWAVGSIM AELYTLRPLF PGTSEVDQIF KICQVLGTPK KNDWPEGYQL AASMNFRFPQ 240

CVPINLKTLI PNASEDALSL MRDTMQWDPK KRPTASQALR HPYFQVGQAL GPPVQYVEQK 300

KPLNKAPKPQ EPRPIYVTKM QSSSSSEILE KSSPDTPPAT NRPLQQIQVP QSTDDIQLPS 360

KTQQVVLPSI SKTISPKPVA NGPQTSAVSI KHGRRRWGQS VVKDSWDEID TDFGISYSKK 420

PTMALAKENK PEDSLFGLSD PISIVDENKG SSIVGMKRTD TSQTTSAKQH YLRQSRYLPG 480

MNPKNAGLIS ANKDGKHATW NSALTTKPLG PIGAGLGFSK ANGAGILGGF IGPSYNSPGG 540

YIPSFNKKEV GSAGQRIQLA PIGAATTAPV ISDAVNGKVK LTKPKSTTLR TLPDNAADYD 600

AWKPKAVRSQ MPAPPFKPAA GNLSILNRPQ PLQAVHGRTD WVAKYGGHR 649

Nucleotide Sequence
(FASTA)

ATGAACCGAT ATACAACCAT GAAACAACTG GGTGATGGCA CTTATGGAAG TGTTTTGATG 60

GGGAGGAGCA ATGAGTCTGG AGAACTGGTA GCTATCAAAA GTCTCACCAA TGCCTTTTTG 120

TGTTGGAAAG CACCCCTCAC TATGCAAACA CAAAAATCTC TGAAGAAACT TAATCATGCC 180

AATGTGGTTA AACTAAAAGA AGTTATCAGA GAGAATGACC AGCTCTTTTT TGTATTTGAG 240

TACATGAAAG AAAATCTTTA TCAGCTGATG AAAGATAGAA ATAAGTTGTT TCCTGAGTCA 300

GTCATCAGAA ACATAATGTA TCAAATTTTA CAAGGTCTAG CTTTTATCCA TAAGCACGGT 360

TTTTTCCATC GTGATATGAA ACCCGAAAAT CTTCTTTGTA TGGGCCCTGA ACTTGTAAAA 420

ATCGCAGATT TTGGATTAGT TAGAGAACTA AGATCTCAGC CACCATATAC TGATTATGTA 480

TCTACCAGAT GGTACAGAGC CCCTGAAGTA TTGCTCAGAT CCTCTTCATA TAGCTCTCCA 540

ATAGATATAT GGGCTGTTGG TAGCATTATG GCTGAACTGT ATACTCTTAG ACCTCTTTTT 600

CCAGGGACAA GTGAGGTTGA CCAGATCTTC AAAATCTGCC AAGTTTTAGG AACCCCCAAA 660

AAGAATGATT GGCCTGAAGG ATATCAGCTT GCAGCGTCAA TGAATTTCCG CTTCCCTCAA 720

TGTGTTCCTA TCAATCTAAA AACCCTCATA CCCAATGCTA GTGAAGATGC TTTATCACTA 780

ATGAGGGACA CAATGCAGTG GGACCCCAAA AAACGGCCAA CAGCCAGTCA GGCTTTAAGA 840

CACCCATATT TTCAAGTTGG ACAAGCATTG GGGCCTCCAG TCCAGTATGT CGAGCAGAAA 900

AAGCCTTTGA ACAAAGCACC AAAACCCCAG GAACCTCGCC CAATATATGT AACAAAAATG 960

CAGTCTTCAT CATCATCTGA AATTTTAGAG AAATCATCAC CTGATACACC ACCTGCAACC 1020

AACCGACCTC TACAGCAAAT TCAGGTGCCA CAGAGTACAG ATGATATTCA GCTGCCATCC 1080

AAAACTCAGC AAGTGGTTCT TCCCAGCATC AGCAAAACTA TTTCTCCGAA ACCTGTAGCC 1140

AATGGACCAC AGACCAGTGC TGTCAGCATT AAACATGGAC GACGACGCTG GGGTCAGTCT 1200

GTTGTTAAGG ACAGCTGGGA TGAAATTGAT ACAGACTTTG GAATTTCATA TTCAAAGAAA 1260

CCCACGATGG CTCTAGCAAA GGAAAACAAA CCTGAGGATT CGTTATTTGG TTTGTCAGAT 1320

CCCATTTCCA TCGTTGACGA AAACAAAGGT TCTTCAATTG TTGGCATGAA GAGAACAGAC 1380

ACAAGTCAAA CGACTTCAGC CAAGCAGCAC TATCTCAGGC AGTCACGATA CTTACCTGGC 1440

ATGAACCCCA AAAATGCAGG GTTAATTTCT GCTAATAAAG ATGGAAAGCA TGCCACGTGG 1500

AACAGTGCCC TAACAACGAA ACCACTAGGC CCGATAGGAG CAGGCCTTGG TTTCAGTAAA 1560

GCTAATGGAG CAGGCATTTT AGGAGGTTTC ATAGGCCCCT CCTACAACTC ACCTGGAGGA 1620

TACATCCCTT CATTTAACAA GAAGGAAGTT GGATCAGCAG GGCAGAGAAT ACAGTTGGCA 1680

CCAATTGGAG CAGCAACAAC TGCACCTGTT ATCAGTGATG CTGTGAATGG TAAAGTAAAA 1740

CTTACCAAGC CAAAATCTAC CACACTAAGA ACCTTACCTG ATAACGCTGC AGATTATGAT 1800

GCTTGGAAAC CAAAAGCTGT ACGCTCTCAG ATGCCAGCTC CACCTTTCAA GCCAGCTGCT 1860

GGAAATCTAT CTATATTAAA CCGCCCTCAG CCACTGCAGG CAGTCCATGG AAGAACAGAC 1920

TGGGTAGCCA AATATGGAGG CCATCGTTAA 1950

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++k+lGdGt+g+vl+++s+++gelvaik + + f  ++    ++  kslkkln h+n+

Q: 4     YTTMKQLGDGTYGSVLMGRSNESGELVAIKSLTNAFLCWKAPLTMQTQKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         +klkevi  rend+l++v+e+m+enlyql+kdr+kl++es++++i+yqil+glafihkhg

Q: 63    VKLKEVI--RENDQLFFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l++g+elvk+adfGl+re+rs++PytdyvstrwyraPevllrs++yssp

Q: 121   FFHRDMKPENLLCMGPELVKIADFGLVRELRSQPPYTDYVSTRWYRAPEVLLRSSSYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavG+++ae+++lrplfPG+se+dqifki++vlGtPkk++w+e+y+la ++n++fpq

Q: 181   IDIWAVGSIMAELYTLRPLFPGTSEVDQIFKICQVLGTPKKNDWPEGYQLAASMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lktl++nas++al+l++d +++dP++r+ta+qal++pyf

Q: 241   CVPINLKTLIPNASEDALSLMRDTMQWDPKKRPTASQALRHPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTMKQLGDG TYGSVLMGRS NESGELVAIK SLTNAFLCWK APLTMQTQKS LKKLNHANVV 60

KLKEVIREND QLFFVFEYMK ENLYQLMKDR NKLFPESVIR NIMYQILQGL AFIHKHGFFH 120

RDMKPENLLC MGPELVKIAD FGLVRELRSQ PPYTDYVSTR WYRAPEVLLR SSSYSSPIDI 180

WAVGSIMAEL YTLRPLFPGT SEVDQIFKIC QVLGTPKKND WPEGYQLAAS MNFRFPQCVP 240

INLKTLIPNA SEDALSLMRD TMQWDPKKRP TASQALRHPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013