EKS-XET-00055

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00055

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	388.8	1.5E-116	137	418	282

Status

Unreviewed

Ensembl Protein

ENSXETP00000004012

UniProt Accession

F6Z6X3;

Protein Name

Protein Synonyms/Alias

Gene Name

cdk17

Gene Synonyms/Alias

cdk17;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000001892	ENSXETP00000004010	ENSXETT00000004010
ENSXETG00000001892	ENSXETP00000004012	ENSXETT00000004012

Organism

Xenopus tropicalis

Functional Description

Protein Length

468

Protein Sequence
(FASTA)

MKKFKRRLSL TLRGSQTIDE SLSELAEQMT IEENSSKDND IVHENLKMGS DGESDQASGT 60

SSDEVQSPTG VCLRNRIHRR ISMEDLNKRL SLPADIRIPD GYLEKLQINS PPFDQPMSRR 120

SRRASLSEIG FGKMETYVKL EKLGEGTYAT VFKGRSKLTE NLVALKEIRL EHEEGAPCTA 180

IREVSLLKDL KHANIVTLHD IVHTDKSLTL VFEYLDKDLK QYMDDCGNIM SIHNVKIFLY 240

QILRGLAYCH KRKVLHRDLK PQNLLINEKG ELKLADFGLA RAKSVPTKTY SNEVVTLWYR 300

PPDVLLGSSE YSTQIDMWGV GCIFFEMASG RPLFPGSTVE DELHLIFRLL GTPAEETWPG 360

ISSNDEFRNY NFPKYKPQPV INHAPRLDSE GIELLTRFLQ YESKKRISAE DAMKHAYFRS 420

LGTKIHSLPE NISIFSLKDI QLQKDPGFRN SSYPETGHGK NRRQSMLF 468

Nucleotide Sequence
(FASTA)

ATGAAAAAAT TCAAGCGAAG GCTTTCACTC ACATTGAGAG GCAGCCAGAC AATTGACGAA 60

TCGCTCTCAG AGCTGGCAGA ACAAATGACC ATTGAAGAAA ATAGCAGTAA AGATAACGAT 120

ATAGTACATG AAAACCTAAA GATGGGATCA GATGGTGAAA GTGACCAAGC ATCTGGGACA 180

TCATCAGATG AAGTTCAGTC ACCAACAGGA GTGTGCCTCA GAAATCGAAT ACACAGGCGC 240

ATTTCAATGG AGGACCTGAA CAAGAGGCTG TCACTTCCAG CTGATATTAG GATACCTGAT 300

GGATATTTGG AAAAGCTGCA AATCAACAGT CCTCCGTTTG ATCAACCTAT GAGCAGAAGG 360

TCACGTAGAG CATCATTATC AGAAATTGGC TTTGGCAAGA TGGAAACATA TGTCAAATTG 420

GAAAAACTTG GAGAGGGTAC ATACGCAACA GTATTCAAAG GAAGAAGTAA ATTGACAGAA 480

AACCTTGTTG CGCTAAAAGA AATTCGATTG GAACATGAAG AAGGAGCACC TTGTACAGCT 540

ATTAGAGAAG TATCATTACT AAAGGACCTA AAGCATGCAA ACATTGTCAC TTTACATGAT 600

ATTGTCCACA CGGACAAATC ACTGACGCTT GTCTTCGAAT ATCTGGACAA AGATTTAAAG 660

CAGTATATGG ATGACTGTGG GAATATTATG AGCATACACA ATGTAAAGAT ATTTTTGTAC 720

CAAATTCTGC GTGGCTTGGC TTACTGTCAC AAAAGGAAAG TTCTTCACAG AGATCTGAAA 780

CCACAGAACC TGCTAATAAA TGAAAAAGGC GAATTAAAAT TGGCTGATTT TGGCTTGGCC 840

AGAGCAAAAA GTGTTCCAAC AAAAACCTAT TCCAATGAGG TTGTGACATT ATGGTACAGG 900

CCTCCTGATG TCCTGCTTGG GTCTTCTGAA TACTCCACTC AAATTGATAT GTGGGGCGTT 960

GGCTGTATAT TTTTTGAAAT GGCTTCAGGA AGGCCTCTGT TTCCTGGTTC TACAGTGGAA 1020

GATGAACTTC ACTTGATATT CCGGCTTTTA GGAACTCCAG CTGAAGAAAC ATGGCCCGGA 1080

ATCTCTTCAA ATGATGAATT TAGGAACTAC AATTTTCCGA AGTACAAACC ACAGCCTGTT 1140

ATCAACCATG CACCAAGGTT AGACTCAGAG GGTATTGAGT TATTAACACG GTTTCTTCAG 1200

TATGAATCTA AAAAGAGGAT TTCTGCAGAA GATGCAATGA AACACGCTTA CTTCCGAAGT 1260

CTAGGGACTA AAATCCACAG TTTGCCAGAA AATATCTCAA TATTCAGTCT TAAGGATATC 1320

CAATTGCAAA AGGATCCCGG TTTTCGAAAT TCTTCATATC CAGAGACAGG TCATGGGAAG 1380

AACAGAAGGC AAAGCATGCT ATTCTAA 1407

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y klek+geGty++v+k+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 137   YVKLEKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  195

         789*********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++v+ ++k+l+Lvfe+l++dLk++++++ +  +s ++vk +l+q+l+glay+H++k

Q: 196   VTLHDIVH-TDKSLTLVFEYLDKDLKQYMDDCGN-IMSIHNVKIFLYQILRGLAYCHKRK  253

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eYst

Q: 254   VLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYST  313

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e+++ +plf+g++  d+l+ if+llgtp e++wp++s+  e++ ++fp

Q: 314   QIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPAEETWPGISSNDEFRnYNFP  373

         ******************************************************989***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k+k++ + ++ ++l++++++ll+++l+++ kkRisa++a++h yf

Q: 374   KYKPQPVINHAPRLDSEGIELLTRFLQYESKKRISAEDAMKHAYF  418

         ********************************************9

Domain Sequence
(FASTA)

YVKLEKLGEG TYATVFKGRS KLTENLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIVHTDK SLTLVFEYLD KDLKQYMDDC GNIMSIHNVK IFLYQILRGL AYCHKRKVLH 120

RDLKPQNLLI NEKGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSSEYSTQID 180

MWGVGCIFFE MASGRPLFPG STVEDELHLI FRLLGTPAEE TWPGISSNDE FRNYNFPKYK 240

PQPVINHAPR LDSEGIELLT RFLQYESKKR ISAEDAMKHA YF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013