EKS-XET-00352

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00352

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	440.1	3.8E-132	238	526	289

Status

Unreviewed

Ensembl Protein

ENSXETP00000007891

UniProt Accession

F6TXB5;

Protein Name

Protein Synonyms/Alias

Gene Name

bmpr1a

Gene Synonyms/Alias

bmpr1a;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000003655	ENSXETP00000007891	ENSXETT00000007891

Organism

Xenopus tropicalis

Functional Description

Protein Length

537

Protein Sequence
(FASTA)

QTYVAIMQSA LVAFLFILLT HSFPLAGQDL NILPHRTGMK SNSDPKKQEN GVTLAPEDTL 60

PFLYCYCSGY CPENAVNNTC MIRTEHCLVI VVARDWPQRS CHSGTIFYAG TKLHGWVARV 120

ATLKSSSMLG ETDFCNRDLQ PTLSPNILAP DAEYGLRFIA LIISLVVCVI IIAGFILIIW 180

LYKHKLHSQR MLYNRNLDPD DAFIPAGESL KALIDISQSS GSGSGLPLLV QRTIAKQIQM 240

VRQIGKGRYG EVWMGKWRGE KVAVKVFFTA EEASWFRETE IYQTVLMRHE NILVGFIAAD 300

IKGTGSWTQM YLITEYHENG SLYDFLKCTT LDTRSLLKLA YSAACGLCHL HTEIYGTQGK 360

PAIAHRDLKS KNILIKENWT CCIADLGLAV KFNSDTHEVD IPLNTRVGTK RYMAPEVLDE 420

SLNKNHFQAY IMADIYSFSL IIWEMTRRCI TGGIVEEYQL PYYDMVPNDP SFEDMRDVVC 480

MKCLRPTVSN RWNSDECLRA VLKLMAECWA QNPASRLTAL RIKKTLAKMV ESQDVKI 537

Nucleotide Sequence
(FASTA)

CAGACCTATG TAGCCATCAT GCAGTCTGCA CTGGTGGCAT TCCTATTTAT TTTGCTGACA 60

CACTCTTTTC CACTTGCAGG ACAGGACTTG AACATCTTGC CACACAGAAC AGGAATGAAA 120

TCAAATTCAG ACCCAAAGAA GCAGGAAAAT GGTGTAACAC TGGCACCAGA GGATACACTA 180

CCATTTCTAT ATTGTTACTG CTCTGGATAC TGTCCTGAAA ATGCTGTAAA CAATACATGC 240

ATGATCAGAA CCGAGCATTG CTTAGTGATT GTGGTGGCAC GTGATTGGCC TCAAAGATCC 300

TGCCATTCGG GGACAATTTT CTATGCTGGA ACGAAACTAC ATGGATGGGT GGCAAGAGTG 360

GCCACACTCA AAAGCTCCAG TATGTTGGGG GAAACTGATT TCTGTAACCG AGACTTGCAG 420

CCCACATTGT CACCAAACAT ACTTGCGCCA GATGCAGAAT ATGGTTTGCG CTTCATTGCT 480

CTTATCATTT CGTTGGTGGT CTGTGTGATT ATTATAGCCG GCTTCATTCT TATCATTTGG 540

CTTTACAAAC ATAAACTGCA TTCCCAAAGG ATGCTATATA ACAGGAATTT GGACCCCGAT 600

GATGCCTTTA TACCTGCAGG GGAGTCCCTT AAGGCTCTTA TTGATATATC ACAAAGCTCT 660

GGTAGTGGCT CTGGGCTGCC TTTATTGGTG CAGCGTACTA TAGCAAAGCA GATCCAAATG 720

GTTAGACAGA TAGGAAAGGG AAGGTATGGT GAAGTATGGA TGGGAAAATG GAGAGGAGAG 780

AAGGTGGCTG TCAAAGTGTT CTTTACTGCT GAAGAAGCCA GCTGGTTCCG GGAAACTGAA 840

ATCTACCAAA CTGTCCTCAT GCGACATGAG AATATACTTG TAGGTTTCAT AGCAGCTGAT 900

ATTAAAGGAA CAGGCTCATG GACACAAATG TACCTAATAA CAGAGTATCA TGAAAATGGA 960

TCATTGTATG ACTTCCTTAA GTGTACCACT CTGGATACTA GATCTTTACT CAAGCTTGCT 1020

TATTCAGCAG CCTGTGGATT ATGTCACCTC CACACTGAAA TATATGGCAC TCAAGGAAAA 1080

CCTGCCATTG CACACAGGGA TCTGAAAAGT AAAAACATAC TTATAAAAGA AAATTGGACA 1140

TGCTGCATTG CTGACCTGGG ACTTGCAGTA AAATTTAACA GTGATACACA TGAAGTTGAT 1200

ATACCCCTGA ACACACGTGT GGGGACAAAG CGTTATATGG CCCCAGAAGT TCTGGATGAA 1260

AGTCTAAATA AGAATCACTT CCAGGCATAT ATTATGGCAG ATATCTACAG CTTCAGTTTA 1320

ATTATCTGGG AGATGACCCG TCGCTGCATA ACTGGAGGAA TTGTTGAAGA GTATCAGCTA 1380

CCTTACTATG ACATGGTGCC AAATGATCCA TCCTTTGAGG ATATGAGAGA CGTTGTCTGC 1440

ATGAAATGTC TAAGACCTAC AGTTTCAAAT AGGTGGAACA GCGATGAATG TTTGAGAGCT 1500

GTTTTAAAAC TGATGGCAGA GTGCTGGGCT CAAAACCCTG CTTCCCGGCT CACTGCTCTA 1560

CGAATCAAGA AGACACTTGC AAAGATGGTG GAGTCCCAGG ACGTCAAGAT TTGA 1614

Domain Profile

S: 1     lklleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenil.qfi  59

         ++++++igkGrygeVw++k+rge+vAvK+f+t++easw+rE+eiyqtvl+rhenil +fi

Q: 238   IQMVRQIGKGRYGEVWMGKWRGEKVAVKVFFTAEEASWFRETEIYQTVLMRHENILvGFI  297

         799***************************************************9648**

S: 60    aadkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgt  119

         aad+k ++s+t+++l+teyhe+gsL+d+Lk +tld+++ll+la+s+a+Gl+hLH+ei gt

Q: 298   AADIKGTGSWTQMYLITEYHENGSLYDFLKCTTLDTRSLLKLAYSAACGLCHLHTEIYGT  357

         ************************************************************

S: 120   kgkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaP  179

         +g  KpaiaHRDlkskNil+k++ tcciaDlGLa+k++++++e+d+  n++vGtkRYmaP

Q: 358   QG--KPAIAHRDLKSKNILIKENWTCCIADLGLAVKFNSDTHEVDIPLNTRVGTKRYMAP  415

         **..********************************************************

S: 180   EvleealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPslee  239

         Evl+e+ln ++f+a+ +aD+Ys++L++WE+++Rc + +++veey+lp++++v++dPs+e+

Q: 416   EVLDESLNKNHFQAYIMADIYSFSLIIWEMTRRCIT-GGIVEEYQLPYYDMVPNDPSFED  474

         ************************************.***********************

S: 240   mkevvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         m++vv++k lrP+++++w+++e+l+++ kl+ ecW+++p++Rltalr+kk+l

Q: 475   MRDVVCMKCLRPTVSNRWNSDECLRAVLKLMAECWAQNPASRLTALRIKKTL  526

         **************************************************97

Domain Sequence
(FASTA)

IQMVRQIGKG RYGEVWMGKW RGEKVAVKVF FTAEEASWFR ETEIYQTVLM RHENILVGFI 60

AADIKGTGSW TQMYLITEYH ENGSLYDFLK CTTLDTRSLL KLAYSAACGL CHLHTEIYGT 120

QGKPAIAHRD LKSKNILIKE NWTCCIADLG LAVKFNSDTH EVDIPLNTRV GTKRYMAPEV 180

LDESLNKNHF QAYIMADIYS FSLIIWEMTR RCITGGIVEE YQLPYYDMVP NDPSFEDMRD 240

VVCMKCLRPT VSNRWNSDEC LRAVLKLMAE CWAQNPASRL TALRIKKTL 289

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0004675	; F:transmembrane receptor protein serine/threonine kinase activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013