EKS-XET-00312

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00312

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PDK1	410.9	2.8E-123	83	345	263

Status

Unreviewed

Ensembl Protein

ENSXETP00000008716

UniProt Accession

F6ZJK5;

Protein Name

Protein Synonyms/Alias

Gene Name

pdpk1

Gene Synonyms/Alias

pdpk1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000004025	ENSXETP00000008718	ENSXETT00000008718
ENSXETG00000004025	ENSXETP00000008716	ENSXETT00000008716

Organism

Xenopus tropicalis

Functional Description

Protein Length

558

Protein Sequence
(FASTA)

LGRTSSMLYD AIPIQSSVDL CSCPSSSIVR SSSDSSSSPV LGSRPSTNMD VRAVESRTNS 60

LPHPGQQEQQ HPQQPRKKRP QDFKFGKILG EGSFSTVVLA KELTTGREYA VKILQKRHIM 120

KENKVQYVNR EKDVMSRLDH PFFVKLYFTF QDPEKLYFGL SYAKNGELLK YIRKIGSFDE 180

TCTRFYTAEI VCALEYLHEN GIIHRDLKPE NILLSEDMHI QITDFGTAKV SSSDSKQELV 240

RANSFVGTAQ YVSPELLTEK SACKSSDLWA LGCIVYQLVA GLPPFRAGNE YLIFQKIIKL 300

EYDFPEKFFP KAKDLVEKLL VIDPTKRLGC EELGGYGPLK AHPFFETVTW QDLHLQTPPK 360

LTAYLPAMSE DDEDCYGNYD DLLSQFGCMQ VATSASSPSL APLEPLLSQR CGSNIEQYIH 420

DLDNNSFELD LQFSEAEKRL LLEKQVGGNQ WHQFVENNLI VKMGPVDKRK GLFARRRQLL 480

LTEGPHLYYV DPVNKVLKGE IPWSQELRPE AKNFKTFFVH TPNRTYYLMD PSGNAHKWCK 540

KIQEVWRHRY QNHQNSGI 558

Nucleotide Sequence
(FASTA)

CTTGGCAGGA CAAGCTCTAT GCTGTATGAT GCTATCCCTA TTCAGTCAAG TGTGGACCTA 60

TGTTCCTGCC CATCATCTTC AATTGTGAGA AGCTCATCAG ACTCCAGCTC TTCACCAGTC 120

CTTGGCAGTA GACCAAGTAC CAACATGGAT GTGAGGGCTG TAGAGTCCAG AACAAATTCA 180

TTGCCACACC CAGGGCAGCA AGAACAACAG CACCCTCAAC AGCCTCGAAA GAAGAGACCC 240

CAGGATTTCA AGTTTGGAAA AATCCTGGGG GAAGGTTCTT TTTCAACAGT TGTCTTAGCC 300

AAAGAGTTAA CAACAGGAAG AGAATATGCC GTTAAAATTT TACAGAAGCG GCATATAATG 360

AAGGAGAACA AGGTACAATA TGTGAACAGG GAAAAAGATG TTATGTCCCG TTTGGACCAC 420

CCATTCTTCG TCAAACTTTA TTTCACATTT CAAGATCCTG AAAAGCTCTA TTTTGGTCTT 480

AGTTATGCTA AGAACGGAGA ACTACTAAAG TACATACGAA AGATTGGCTC ATTTGATGAA 540

ACCTGCACAA GATTTTATAC TGCTGAAATT GTGTGTGCTT TAGAATATCT GCACGAGAAT 600

GGAATTATTC ACAGGGACCT TAAGCCAGAA AACATTCTAC TTAGTGAGGA CATGCACATT 660

CAAATAACAG ACTTTGGGAC TGCCAAGGTG TCATCGTCTG ACAGCAAACA AGAACTAGTG 720

CGAGCAAATT CATTTGTAGG AACAGCACAG TACGTGTCAC CTGAGTTACT GACTGAAAAA 780

TCAGCATGTA AAAGTTCAGA CCTGTGGGCA CTAGGATGTA TCGTTTATCA GCTGGTAGCA 840

GGATTGCCAC CATTCAGAGC TGGGAATGAA TACCTTATAT TTCAGAAGAT AATTAAGCTG 900

GAATACGACT TCCCTGAAAA ATTCTTTCCA AAGGCTAAAG ACCTAGTAGA AAAACTTTTG 960

GTTATAGATC CTACTAAACG ATTAGGCTGC GAAGAGTTGG GAGGCTACGG ACCTCTAAAA 1020

GCACATCCAT TTTTTGAGAC CGTTACATGG CAAGATTTGC ACCTGCAAAC TCCACCAAAA 1080

CTTACAGCAT ATTTACCGGC AATGTCTGAA GATGACGAGG ATTGCTATGG GAATTATGAT 1140

GACCTCCTGA GTCAGTTTGG CTGCATGCAG GTAGCAACCT CAGCGTCTTC CCCTTCGCTG 1200

GCACCTTTAG AACCTCTTCT TTCTCAGAGG TGTGGCAGTA ACATAGAGCA ATACATACAT 1260

GACCTTGATA ACAATTCATT TGAGCTTGAT CTCCAGTTCT CTGAAGCAGA GAAGCGACTA 1320

CTTCTGGAGA AGCAAGTGGG AGGAAATCAG TGGCATCAGT TTGTAGAAAA TAATTTAATT 1380

GTAAAAATGG GTCCAGTAGA CAAAAGAAAG GGTTTATTTG CTCGTCGGCG CCAACTACTC 1440

CTCACAGAAG GTCCACATTT ATATTATGTA GATCCTGTAA ACAAAGTGCT GAAAGGCGAG 1500

ATCCCATGGT CACAAGAACT GCGCCCAGAG GCTAAGAATT TTAAAACTTT TTTCGTACAC 1560

ACACCAAACA GAACCTATTA TCTAATGGAC CCAAGTGGAA ACGCTCACAA ATGGTGCAAA 1620

AAGATCCAGG AAGTGTGGCG ACACAGATAC CAGAACCATC AGAACAGTGG CATATAG 1677

Domain Profile

S: 1     fkfekelgeGsystvvlarekeskkeyaikvlekryiikekkvkyvtrekevlaklnehp  60

         fkf+k+lgeGs+stvvla+e+++ +eya+k+l+kr+i+ke+kv+yv+rek+v+++l +hp

Q: 83    FKFGKILGEGSFSTVVLAKELTTGREYAVKILQKRHIMKENKVQYVNREKDVMSRL-DHP  141

         89******************************************************.9**

S: 61    givkLyatfqDeeslyfvleyakkGdllellkkvgsfdeactryyaaellsaleflhkkg  120

         ++vkLy+tfqD e+lyf l+yak+G+ll++++k+gsfde+ctr+y+ae++ ale+lh++g

Q: 142   FFVKLYFTFQDPEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVCALEYLHENG  201

         ************************************************************

S: 121   iihrDlkpeniLldkdgkilitDfGsakvlepklkedskkeeeesarsksfvGtaeyvsP  180

         iihrDlkpeniLl +d++i+itDfG+akv ++++k+       e  r++sfvGta+yvsP

Q: 202   IIHRDLKPENILLSEDMHIQITDFGTAKVSSSDSKQ-------ELVRANSFVGTAQYVSP  254

         ****************************98555554.......789**************

S: 181   elLtdsevskssDlWalgcilyqllaGkpPfraeneylifkkilkleyafpegfpekakd  240

         elLt+++++kssDlWalgci+yql+aG+pPfra neylif+ki+kley+fpe+f++kakd

Q: 255   ELLTEKSACKSSDLWALGCIVYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKAKD  314

         ************************************************************

S: 241   lveklLvkdakerltlee......ikahkff  265

         lveklLv+d+++rl++ee      +kah+ff

Q: 315   LVEKLLVIDPTKRLGCEElggygpLKAHPFF  345

         ******************************9

Domain Sequence
(FASTA)

FKFGKILGEG SFSTVVLAKE LTTGREYAVK ILQKRHIMKE NKVQYVNREK DVMSRLDHPF 60

FVKLYFTFQD PEKLYFGLSY AKNGELLKYI RKIGSFDETC TRFYTAEIVC ALEYLHENGI 120

IHRDLKPENI LLSEDMHIQI TDFGTAKVSS SDSKQELVRA NSFVGTAQYV SPELLTEKSA 180

CKSSDLWALG CIVYQLVAGL PPFRAGNEYL IFQKIIKLEY DFPEKFFPKA KDLVEKLLVI 240

DPTKRLGCEE LGGYGPLKAH PFF 263

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR011993	; PH_like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013