EKS-XET-00147

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00147

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TLK	613.9	3.7E-185	408	686	279

Status

Unreviewed

Ensembl Protein

ENSXETP00000012505

UniProt Accession

F6U771;

Protein Name

Protein Synonyms/Alias

Gene Name

pcmtd1

Gene Synonyms/Alias

pcmtd1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000005672	ENSXETP00000012505	ENSXETT00000012505

Organism

Xenopus tropicalis

Functional Description

Protein Length

718

Protein Sequence
(FASTA)

VMDELHSLDP RRQELLEARF TGGVSGSTGS TGSSVGAKAS NNESSNHSFG SLGSLSDKES 60

ETPEKKQPDS SRGRKRKAEN QSESSQAGKN SGGRGHKISD YFDYQAGNGT SPVRGLPPSI 120

RSPQNSHSHS TPSSSARQNS PSPTALAFGD HLLSQTKQLS YKLVQTDLTM LKLAALESNK 180

NQDLEKKEGR IDDLLRTNCD LRRQIDEQQK ILEKYKERLN KCISMSKKLL IEKSTQEKLA 240

SREKSMQDRL RLGHFTTVRH GASFTEQWTD GFAFQNLVKQ QEWVNQQRED IERQRKQLAK 300

RKPPSSNSSQ TPSANSEPKQ RKNKAVNGAE NDPFVKPSLP QLLTLAEYHE QEEIFKLRLG 360

HLKKEEAEIQ AELERLERVR NLHIRELKRI NNEDNSQFKD HPTLNERYLL LHLLGRGGFS 420

EVYKAFDLYE QRYAAVKIHQ LNKSWRDEKK ENYHKHACRE YRIHKELDHP RIVKLYDYFS 480

LDTDTFCTVL EYCEGNDLDF YLKQHKLMSE KEARSIVMQI VNALRYLNEI KPPIIHYDLK 540

PGNILLVDGT ACGEIKITDF GLSKIMDDDS YGVDGMDLTS QGAGTYWYLP PECFVVGKEP 600

PKISNKVDVW SVGVIFFQCL YGRKPFGHNQ SQQDILQENT ILKATEVQFP VKPVVSNEAK 660

AFIRRCLAYR KEDRFDVHQL ANDAYLLPHM RRSNSSGNLH MSGLVASPTT PTSSIISY 718

Nucleotide Sequence
(FASTA)

GTCATGGATG AACTCCACAG CTTGGACCCC AGGCGGCAGG AATTGTTGGA GGCCAGATTT 60

ACAGGGGGAG TAAGTGGCAG TACTGGTAGC ACGGGGAGCA GTGTGGGAGC AAAAGCATCA 120

AACAATGAGA GCTCAAACCA CAGTTTTGGA AGTCTGGGTT CTTTAAGTGA TAAAGAGTCA 180

GAGACTCCAG AAAAAAAGCA GCCAGACTCA TCCAGAGGAA GAAAGAGAAA GGCAGAGAAT 240

CAGAGTGAAA GCAGTCAAGC AGGAAAAAAT AGCGGGGGAC GTGGCCATAA AATTAGTGAT 300

TATTTTGACT ACCAAGCTGG GAATGGTACC AGTCCTGTAA GAGGCCTGCC TCCATCAATC 360

CGGTCGCCTC AGAACTCACA CTCACATTCC ACTCCTTCAT CCTCTGCTCG ACAGAACAGC 420

CCTTCCCCCA CTGCATTAGC TTTTGGGGAC CATCTACTTA GCCAGACAAA ACAGTTATCA 480

TATAAACTAG TTCAGACGGA TCTTACAATG CTGAAATTAG CTGCTCTAGA AAGTAATAAA 540

AACCAGGACC TGGAAAAAAA AGAAGGAAGA ATAGATGATT TGCTCAGGAC TAACTGTGAC 600

CTTAGGCGAC AAATAGACGA ACAGCAAAAA ATTCTTGAAA AGTATAAAGA GAGATTAAAT 660

AAGTGCATTT CAATGAGCAA AAAACTCCTG ATAGAAAAGA GCACCCAGGA GAAGCTGGCA 720

AGCAGAGAGA AGAGCATGCA GGACAGGTTA CGGCTAGGAC ATTTCACCAC AGTTCGGCAT 780

GGAGCCTCTT TTACTGAACA GTGGACAGAT GGCTTCGCTT TCCAAAACCT TGTCAAGCAA 840

CAGGAATGGG TGAATCAGCA GAGAGAAGAT ATTGAAAGAC AAAGAAAACA ACTGGCCAAG 900

CGGAAGCCGC CATCATCAAA CAGTTCCCAG ACTCCCTCCG CCAACTCAGA ACCAAAGCAG 960

CGGAAAAACA AAGCTGTAAA TGGAGCTGAA AATGACCCCT TTGTAAAACC AAGTTTACCA 1020

CAGTTATTAA CTTTAGCCGA ATACCATGAA CAGGAAGAAA TTTTTAAGCT TCGACTAGGT 1080

CATTTAAAAA AGGAAGAAGC CGAAATTCAG GCAGAGTTGG AAAGGTTAGA GAGGGTTAGA 1140

AATCTTCATA TACGGGAGCT TAAAAGAATA AACAATGAAG ATAATTCACA ATTTAAAGAC 1200

CACCCTACAC TGAACGAACG GTATTTATTA CTACATCTAT TAGGTCGAGG CGGCTTTAGT 1260

GAAGTGTACA AGGCTTTTGA TCTTTATGAA CAAAGATATG CTGCTGTAAA AATCCACCAG 1320

CTTAACAAGA GCTGGAGGGA CGAGAAGAAA GAAAACTACC ACAAGCATGC CTGCAGAGAG 1380

TACAGAATAC ACAAAGAACT GGATCACCCC CGAATAGTTA AACTTTACGA TTATTTTTCC 1440

TTGGATACAG ACACGTTTTG TACAGTGCTA GAATACTGTG AAGGCAATGA CCTCGACTTC 1500

TACCTAAAGC AGCACAAGTT GATGTCGGAA AAGGAAGCCA GGTCTATTGT AATGCAAATA 1560

GTCAATGCAC TACGTTATCT CAATGAGATC AAGCCTCCCA TTATCCACTA CGACCTAAAG 1620

CCAGGAAATA TCCTTCTTGT GGACGGGACA GCTTGTGGAG AAATAAAAAT CACCGACTTC 1680

GGTTTGTCCA AGATAATGGA TGACGACAGC TATGGTGTGG ATGGAATGGA CTTGACTTCT 1740

CAAGGAGCAG GGACATACTG GTATTTACCA CCAGAGTGTT TTGTCGTGGG CAAGGAGCCC 1800

CCGAAAATCT CCAACAAAGT TGACGTGTGG TCTGTAGGAG TCATTTTTTT CCAGTGTCTC 1860

TATGGCAGAA AGCCATTTGG CCACAATCAG TCTCAACAGG ATATCTTACA GGAAAATACA 1920

ATATTAAAAG CCACAGAAGT ACAGTTTCCA GTGAAGCCTG TTGTAAGCAA TGAAGCCAAG 1980

GCCTTTATTA GACGATGCTT AGCCTACCGC AAGGAGGACA GGTTTGATGT CCACCAACTG 2040

GCCAATGACG CGTATCTTCT CCCGCATATG AGAAGATCCA ACTCTTCAGG AAACCTCCAT 2100

ATGTCTGGGC TAGTGGCCTC TCCAACCACT CCCACATCAA GCATCATTTC ATACTGA 2157

Domain Profile

S: 1     ylllkllgkggfsevykafdlkeqryvavkihqlnkdwkdekkenyvkhalreyrihkel  60

         ylll+llg+ggfsevykafdl+eqry+avkihqlnk+w+dekkeny+kha+reyrihkel

Q: 408   YLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKEL  467

         9***********************************************************

S: 61    dhprivklydllsldtdsfctvleyvegndldfylkqhkllsekearsiimqivsalkyl  120

         dhprivklyd++sldtd+fctvley+egndldfylkqhkl+sekearsi+mqiv+al+yl

Q: 468   DHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYL  527

         ************************************************************

S: 121   neikppiihydlkpgnillvegtacgeikitdfglskimdddsydsddgleltsqgagty  180

         neikppiihydlkpgnillv+gtacgeikitdfglskimdddsy++d g++ltsqgagty

Q: 528   NEIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYGVD-GMDLTSQGAGTY  586

         *********************************************99.************

S: 181   wylppecfvvgkeppkisnkvdvwsvgvifyqclygkkpfghnqsqqdileentilkate  240

         wylppecfvvgkeppkisnkvdvwsvgvif+qclyg+kpfghnqsqqdil+entilkate

Q: 587   WYLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATE  646

         ************************************************************

S: 241   vqfpskpvvsseakafirrclayrkedridvqqlakdeyl  280

         vqfp+kpvvs+eakafirrclayrkedr+dv+qla+d yl

Q: 647   VQFPVKPVVSNEAKAFIRRCLAYRKEDRFDVHQLANDAYL  686

         *************************************997

Domain Sequence
(FASTA)

YLLLHLLGRG GFSEVYKAFD LYEQRYAAVK IHQLNKSWRD EKKENYHKHA CREYRIHKEL 60

DHPRIVKLYD YFSLDTDTFC TVLEYCEGND LDFYLKQHKL MSEKEARSIV MQIVNALRYL 120

NEIKPPIIHY DLKPGNILLV DGTACGEIKI TDFGLSKIMD DDSYGVDGMD LTSQGAGTYW 180

YLPPECFVVG KEPPKISNKV DVWSVGVIFF QCLYGRKPFG HNQSQQDILQ ENTILKATEV 240

QFPVKPVVSN EAKAFIRRCL AYRKEDRFDV HQLANDAYL 279

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013