EKS-XET-00628

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00628

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK2	586.0	8.9E-177	14	272	259

Status

Unreviewed

Ensembl Protein

ENSXETP00000014163

UniProt Accession

F6YQ17; F6YQ07;

Protein Name

Protein Synonyms/Alias

Gene Name

camk2a

Gene Synonyms/Alias

camk2a; camk2g;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000006455	ENSXETP00000014163	ENSXETT00000014163
ENSXETG00000006455	ENSXETP00000014164	ENSXETT00000014164

Organism

Xenopus tropicalis

Functional Description

Protein Length

563

Protein Sequence
(FASTA)

MATTATCTRF TDEYQLYEEL GKGAFSVVRR CVKKSSNQEY AAKIINTKKL SARDHQKLER 60

EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIHQI 120

LESVNHIHQH DIVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY 180

LSPEVLRKDP YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT 240

VTPEAKNLIN QMLTINPAKR ITADQALKHP WVCQRSTVAS MMHRQETVEC LRKFNARRKL 300

KGAILTTMLV SRNFSGIAFG CRKAASTVPC TSSTGDTITG VGRQTSAPVV AATSAANLVE 360

QAAKSLLNKK TDGVKPQTNN KNSIISPAKE NPPLQTSMEP QTTVVHNATD GIKGSTESCN 420

TTTEDEDLKV RKQEIIKITE QLIEAINNGD FEAYTKICDP GLTSFEPEAL GNLVEGMDFH 480

KFYFDNLLSK HTKPIHTTIL NPHVHVIGED AACIAYIRLT QYIDAQGRPR TTQSEETRVW 540

YRRDGKWLNV HYHCSGAPAA PLQ 563

Nucleotide Sequence
(FASTA)

ATGGCCACTA CCGCGACTTG CACCCGCTTC ACAGACGAGT ATCAGCTGTA TGAGGAGCTT 60

GGCAAGGGGG CCTTTTCAGT TGTACGAAGA TGTGTGAAGA AATCTTCCAA CCAGGAATAT 120

GCTGCAAAAA TAATAAACAC CAAAAAGCTG TCTGCAAGAG ACCACCAGAA ATTGGAGCGG 180

GAGGCTCGGA TTTGCCGGCT TTTGAAACAC CCTAACATTG TGCGTCTCCA TGACAGTATT 240

TCAGAAGAGG GCTTTCATTA CCTTGTTTTT GATCTGGTGA CTGGCGGAGA GCTGTTTGAA 300

GATATTGTGG CAAGGGAATA TTATAGTGAA GCAGACGCCA GCCACTGTAT TCATCAGATC 360

TTGGAGAGTG TCAACCACAT TCACCAGCAT GATATTGTAC ACAGGGACCT TAAGCCTGAG 420

AATCTTTTGT TGGCAAGCAA ATGCAAGGGG GCTGCTGTAA AACTGGCTGA TTTTGGGCTT 480

GCCATAGAAG TCCAAGGAGA CCAACAAGCA TGGTTTGGGT TTGCAGGAAC TCCAGGATAT 540

CTCTCTCCCG AGGTGTTGAG AAAAGATCCC TATGGGAAAC CAGTAGACAT ATGGGCATGC 600

GGGGTAATTC TGTACATATT ACTAGTGGGC TACCCTCCTT TTTGGGATGA AGATCAACAT 660

AAGCTCTACC AACAGATCAA AGCTGGTGCA TATGATTTCC CGTCACCTGA GTGGGATACA 720

GTGACCCCAG AAGCCAAGAA TTTAATTAAT CAGATGTTGA CAATAAACCC TGCAAAACGT 780

ATCACAGCAG ATCAGGCTCT GAAGCACCCA TGGGTCTGCC AACGATCAAC TGTTGCCTCC 840

ATGATGCACA GACAAGAAAC AGTGGAATGT TTGAGAAAGT TCAATGCACG GAGAAAGCTT 900

AAAGGTGCAA TTCTCACAAC AATGTTGGTT TCTCGGAATT TTTCTGGAAT TGCATTTGGA 960

TGCCGAAAAG CTGCATCCAC TGTCCCGTGT ACCTCTTCAA CGGGGGACAC TATAACTGGT 1020

GTTGGCAGGC AGACCTCCGC CCCTGTTGTG GCCGCCACCA GTGCTGCCAA CTTAGTCGAG 1080

CAAGCTGCCA AGAGTTTGTT GAACAAGAAG ACAGATGGTG TCAAGCCACA GACCAACAAC 1140

AAAAACAGCA TAATAAGCCC TGCAAAAGAA AACCCCCCAT TGCAGACATC AATGGAACCT 1200

CAAACAACTG TTGTCCACAA TGCAACTGAT GGGATAAAAG GATCAACAGA GAGTTGTAAC 1260

ACCACCACTG AAGATGAAGA TCTGAAAGTG CGCAAACAGG AGATCATCAA GATAACAGAA 1320

CAGCTAATTG AAGCTATCAA CAATGGGGAT TTTGAAGCCT ACACGAAAAT CTGTGATCCA 1380

GGATTAACTT CTTTTGAGCC AGAGGCTCTT GGCAACCTTG TTGAAGGGAT GGACTTCCAT 1440

AAGTTTTATT TTGACAACTT GTTGTCCAAA CACACCAAGC CTATCCACAC CACCATCCTG 1500

AATCCGCATG TGCATGTAAT TGGAGAGGAT GCTGCCTGCA TTGCTTACAT CCGGCTGACA 1560

CAGTACATTG ATGCCCAGGG ACGGCCTCGC ACAACACAGT CAGAAGAAAC CAGAGTTTGG 1620

TACCGCAGGG ATGGCAAATG GCTGAATGTC CACTACCACT GTTCTGGGGC CCCAGCCGCC 1680

CCTCTCCAGT GA 1692

Domain Profile

S: 1     yqlfeelgkgafsvvrrcvkvttgqeyaakiintkklsardhqklerearicrllkhpni  60

         yql+eelgkgafsvvrrcvk++++qeyaakiintkklsardhqklerearicrllkhpni

Q: 14    YQLYEELGKGAFSVVRRCVKKSSNQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNI  73

         9***********************************************************

S: 61    vrlhdsiseegfhylvfdlvtggelfedivareyyseadashciqqilesvlhihqngvv  120

         vrlhdsiseegfhylvfdlvtggelfedivareyyseadashci+qilesv+hihq+++v

Q: 74    VRLHDSISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIV  133

         ************************************************************

S: 121   hrdlkpenlllaskakgaavkladfglaievqgdqqawfgfagtpgylspevlrkdpygk  180

         hrdlkpenlllask+kgaavkladfglaievqgdqqawfgfagtpgylspevlrkdpygk

Q: 134   HRDLKPENLLLASKCKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKDPYGK  193

         ************************************************************

S: 181   pvdlwacgvilyillvgyppfwdedqhrlyqqikagaydfpspewdtvtpeakdlinkml  240

         pvd+wacgvilyillvgyppfwdedqh+lyqqikagaydfpspewdtvtpeak+lin+ml

Q: 194   PVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQML  253

         ************************************************************

S: 241   tinpakritadealkhpwi  259

         tinpakritad+alkhpw+

Q: 254   TINPAKRITADQALKHPWV  272

         ******************8

Domain Sequence
(FASTA)

YQLYEELGKG AFSVVRRCVK KSSNQEYAAK IINTKKLSAR DHQKLEREAR ICRLLKHPNI 60

VRLHDSISEE GFHYLVFDLV TGGELFEDIV AREYYSEADA SHCIHQILES VNHIHQHDIV 120

HRDLKPENLL LASKCKGAAV KLADFGLAIE VQGDQQAWFG FAGTPGYLSP EVLRKDPYGK 180

PVDIWACGVI LYILLVGYPP FWDEDQHKLY QQIKAGAYDF PSPEWDTVTP EAKNLINQML 240

TINPAKRITA DQALKHPWV 259

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004683	; F:calmodulin-dependent protein kinase activity
GO:0046777	; P:protein autophosphorylation

KEGG

xtr:100135711

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543	; Ca/CaM-dep_prot_kinase-assoc.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF08332	; CaMKII_AD; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013