EKS-XET-00319

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00319

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	339.5	1.2E-101	27	279	253

Status

Unreviewed

Ensembl Protein

ENSXETP00000015309

UniProt Accession

F6XJN6;

Protein Name

Protein Synonyms/Alias

Gene Name

prkaa1

Gene Synonyms/Alias

prkaa1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000007026	ENSXETP00000015309	ENSXETT00000015309

Organism

Xenopus tropicalis

Functional Description

Protein Length

560

Protein Sequence
(FASTA)

MRRLSSLMKM AADKQKHHDG RVKIGHYILG DTLGVGTFGK VKVGKHELTG HKVAVKILNR 60

QKIRSLDVVG KIRREIQNLK LFRHPHIIKL YQVISTPTDI FMVMEYVSGG ELFDYICKNG 120

KLDEKESRRL FQQILSGVDY CHRHMVVHRD LKPENVLLDA HMNAKIADFG LSNMMADGEF 180

LRTSCGSPNY AAPEVISGRL YAGPEVDIWS CGVILYALLC GTLPFDDDHV PTLFKKICDG 240

IFYTPQYLNP PVISLLKHML LVDPMKRATI KDIREHEWFK LDLPKYLFPE DPSYSSNMID 300

DEALKEVCEK CECLEEEVLS CLYSRNHQDP LAVAYHLIID NRRIMNEAKD FYLATSPPDS 360

FMEEPQVARP HPERVPFLVA ESPRQRHTLD ELNPQKTKHQ VGVRRAKWHL GIRSQSRPND 420

IMAEVCRAMK QLGYEWKVVN PYYLRVRRKN PVTSMYTKMS LQLYQVDSRT YLLDFRSIDD 480

EVTEAKSESA TPRRSGSISN YRPPKNDSDP EIQAKSSDGS GPSSLTSSVD SSNADLVPRP 540

GSHTIEFFEM CANLIKILAR 560

Nucleotide Sequence
(FASTA)

ATGCGCAGGC TCAGTTCGCT CATGAAGATG GCGGCGGATA AACAGAAGCA TCATGACGGG 60

AGGGTGAAGA TCGGTCACTA TATACTGGGC GACACGCTCG GGGTGGGCAC GTTTGGCAAA 120

GTGAAAGTTG GCAAGCATGA GCTTACAGGG CACAAGGTCG CCGTGAAGAT TTTAAACCGG 180

CAGAAGATCC GCAGCCTTGA CGTGGTTGGG AAAATTCGCC GTGAGATCCA GAATCTGAAG 240

CTCTTCAGAC ATCCTCATAT CATTAAGCTG TACCAGGTCA TCAGCACACC AACAGATATC 300

TTTATGGTTA TGGAATATGT TTCTGGCGGG GAACTATTTG ATTATATATG TAAGAATGGG 360

AAGTTGGATG AAAAAGAATC CCGGCGCTTA TTCCAGCAAA TTCTTTCCGG GGTTGATTAT 420

TGCCATAGAC ATATGGTCGT ACACCGAGAC TTGAAGCCTG AGAATGTTCT TCTTGATGCC 480

CACATGAATG CGAAGATTGC GGATTTTGGG CTCTCTAACA TGATGGCTGA TGGTGAATTC 540

CTACGAACCA GCTGCGGTTC CCCTAATTAC GCTGCTCCGG AAGTTATCTC AGGAAGGCTT 600

TATGCTGGCC CAGAGGTGGA CATATGGAGC TGCGGGGTCA TCCTGTATGC GTTACTCTGT 660

GGAACTCTCC CTTTTGATGA TGATCATGTG CCAACACTTT TTAAGAAGAT ATGTGATGGC 720

ATCTTCTACA CACCCCAGTA CCTGAACCCT CCCGTCATTA GCCTTCTAAA GCACATGCTG 780

CTGGTGGATC CCATGAAAAG GGCAACCATC AAAGATATTC GGGAACATGA ATGGTTCAAG 840

CTAGATCTTC CTAAATATCT GTTTCCCGAG GATCCATCGT ACAGTTCCAA TATGATAGAC 900

GACGAAGCCT TAAAAGAAGT GTGTGAGAAG TGCGAGTGCT TGGAGGAGGA AGTGCTGAGC 960

TGCTTGTACA GTCGCAACCA CCAGGACCCG TTGGCAGTCG CCTACCATCT GATCATAGAT 1020

AATCGCCGCA TAATGAATGA GGCCAAAGAC TTCTATTTGG CTACCAGCCC TCCGGATTCC 1080

TTTATGGAAG AGCCTCAAGT TGCTCGGCCT CACCCAGAGA GAGTTCCCTT TTTAGTGGCC 1140

GAGTCACCCC GGCAACGACA CACTCTCGAT GAGTTAAACC CACAAAAGAC CAAACACCAG 1200

GTTGGTGTGA GAAGAGCCAA ATGGCATTTA GGCATTCGAA GTCAGAGCCG CCCAAACGAT 1260

ATCATGGCAG AGGTTTGCCG AGCAATGAAA CAGCTGGGCT ATGAGTGGAA GGTTGTAAAT 1320

CCATACTACC TGCGCGTAAG AAGGAAGAAT CCCGTTACTA GCATGTACAC TAAGATGAGC 1380

CTCCAGCTGT ACCAAGTGGA TAGCAGAACT TACCTGCTGG ATTTCCGCAG CATTGACGAT 1440

GAAGTAACTG AGGCCAAGTC GGAAAGCGCC ACCCCTAGGC GATCAGGCTC CATTAGCAAT 1500

TATCGACCTC CAAAAAATGA CTCGGATCCT GAAATTCAAG CGAAGTCTTC AGACGGCTCA 1560

GGGCCTTCAT CTTTAACCTC ATCAGTGGAC TCTTCCAATG CCGACCTAGT CCCCAGGCCA 1620

GGAAGCCATA CCATAGAATT TTTTGAAATG TGTGCAAATT TAATAAAAAT CCTTGCACGA 1680

TAG 1683

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y l++tlG g+fgkVk+ kh++t++kvavKi++++k+ s + + ki+rEi+ lk ++hp+

Q: 27    YILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIrSLDVVGKIRREIQNLKLFRHPH  86

         8899********************************96667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         iikl++vi+t +++++v+ey+sggeLfdyi ++g+l+eke+r+lf+q++s+v+Y+h++ +

Q: 87    IIKLYQVISTPTDIFMVMEYVSGGELFDYICKNGKLDEKESRRLFQQILSGVDYCHRHMV  146

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlKpeN+lld+++n kiaDFGl+n++ +g+ l+t+cGsp+YaaPe+++g+ Y gp+v

Q: 147   VHRDLKPENVLLDAHMNAKIADFGLSNMMADGEFLRTSCGSPNYAAPEVISGRLYAGPEV  206

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+Ws+Gv+Lyal++g+lPfd++++ +l++ki +g + +p++l++ ++sLl+++L vdp k

Q: 207   DIWSCGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPPVISLLKHMLLVDPMK  266

         ************************************************************

S: 240   Ratieeilkhewl  252

         Rati++i++hew+

Q: 267   RATIKDIREHEWF  279

         ************7

Domain Sequence
(FASTA)

YILGDTLGVG TFGKVKVGKH ELTGHKVAVK ILNRQKIRSL DVVGKIRREI QNLKLFRHPH 60

IIKLYQVIST PTDIFMVMEY VSGGELFDYI CKNGKLDEKE SRRLFQQILS GVDYCHRHMV 120

VHRDLKPENV LLDAHMNAKI ADFGLSNMMA DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV 180

DIWSCGVILY ALLCGTLPFD DDHVPTLFKK ICDGIFYTPQ YLNPPVISLL KHMLLVDPMK 240

RATIKDIREH EWF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013