EKS-XET-00013

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00013

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	495.5	4.1E-149	20	287	268

Status

Unreviewed

Ensembl Protein

ENSXETP00000022186

UniProt Accession

Q6DJ64;

Protein Name

Protein Synonyms/Alias

Phosphorylase kinase, gamma 1 (Muscle);

Gene Name

phkg1

Gene Synonyms/Alias

phkg1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000010064	ENSXETP00000022186	ENSXETT00000022186

Organism

Xenopus tropicalis

Functional Description

Protein Length

388

Protein Sequence
(FASTA)

MTKDEELPDW QTSQEFYEKY EPKEILGRGV SSVVRRCIFK PSREDFAVKI IDITGDHLSS 60

EQIAELRDST VKEIDILKKV SGFPNVIQLK DSYESHTFFF LVFDLMRRGE LFDYLTEKVT 120

LSEKETRKIM RSLLEVVSKL HAYNIVHRDL KPENILLDDD MNIKLTDFGF SCQIQEGEKL 180

KEICGTPGYL APEILHCSMD ENHSGYGKQV DMWSCGVIMY TLLAGSPPFW HRKQMLMLRM 240

IMSGEYHFGS PEWDDRSDTV KDLIARLLVV NPERRLTADE ALIHPFFQQY DVEEVRYFSP 300

FRKFKVVCLT VLASVRIYHY YRKVKPVTKE IIVRDPYAIK PIRKLIDGCA FRIYGHWVKK 360

GEQQNRAALF ENTAKAILLS LAAESNFM 388

Nucleotide Sequence
(FASTA)

ATGACAAAAG ATGAAGAATT ACCAGACTGG CAGACGTCAC AGGAATTCTA TGAGAAGTAT 60

GAGCCAAAAG AGATCTTGGG AAGAGGAGTG AGTAGTGTTG TGCGGCGCTG CATTTTCAAG 120

CCCTCCAGAG AAGACTTTGC AGTGAAAATC ATAGACATCA CTGGAGATCA CTTATCCTCA 180

GAGCAGATTG CAGAACTGCG GGACTCAACA GTCAAGGAGA TCGACATCCT AAAAAAAGTA 240

TCAGGGTTCC CTAATGTCAT CCAGCTAAAG GACAGCTATG AATCCCACAC TTTCTTCTTT 300

CTTGTGTTTG ACTTGATGAG GAGAGGAGAA CTGTTTGATT ACCTTACAGA GAAGGTCACA 360

CTGAGTGAGA AGGAAACAAG GAAGATCATG AGGTCACTGC TGGAAGTTGT CTCCAAACTG 420

CATGCCTACA ACATTGTCCA CAGGGACTTG AAACCAGAAA ACATTCTGCT GGACGATGAC 480

ATGAACATTA AGCTGACTGA CTTTGGTTTC TCTTGTCAGA TCCAAGAGGG GGAAAAGCTA 540

AAAGAAATCT GTGGCACACC AGGATACCTG GCTCCAGAAA TCCTACATTG CTCCATGGAT 600

GAAAACCATT CAGGATATGG TAAACAGGTT GATATGTGGA GCTGTGGAGT TATTATGTAC 660

ACTCTACTGG CTGGATCTCC ACCATTTTGG CACAGAAAGC AGATGCTAAT GTTACGCATG 720

ATTATGAGTG GAGAGTACCA TTTTGGATCA CCAGAGTGGG ATGATCGATC TGACACCGTG 780

AAAGATCTGA TTGCTCGACT GCTAGTTGTT AACCCAGAGA GACGCCTTAC AGCAGATGAA 840

GCCCTAATTC ACCCTTTCTT CCAGCAATAT GATGTAGAAG AAGTGCGTTA TTTTAGCCCA 900

TTTAGGAAAT TTAAAGTGGT CTGCCTGACG GTTCTTGCTT CAGTTCGAAT ATATCACTAC 960

TATAGAAAAG TGAAACCAGT TACCAAGGAG ATAATTGTAC GGGACCCATA TGCAATTAAG 1020

CCCATTCGCA AATTGATTGA TGGATGTGCA TTCAGAATAT ATGGACACTG GGTGAAGAAG 1080

GGAGAACAAC AGAACAGAGC AGCCCTTTTT GAAAACACAG CAAAAGCCAT TCTTCTGTCT 1140

CTGGCTGCAG AGTCCAATTT TATGTAA 1167

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         yepkeilGrGvssvvrrci k++ ++favkiid+++++ls+e++ elr++t+ke++il++

Q: 20    YEPKEILGRGVSSVVRRCIFKPSREDFAVKIIDITGDHLSSEQIAELRDSTVKEIDILKK  79

         9***********************************************************

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         vsG p++i+lkd+yes++f+flvfdlm++Gelfdyltekvtlseketrkimr+lle+v+

Q: 80    VSGFPNVIQLKDSYESHTFFFLVFDLMRRGELFDYLTEKVTLSEKETRKIMRSLLEVVSK  139

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lha nivhrdlkpenilldd++nikl+dfGfs+q++eGekl+e+cGtpgylapeil+csm

Q: 140   LHAYNIVHRDLKPENILLDDDMNIKLTDFGFSCQIQEGEKLKEICGTPGYLAPEILHCSM  199

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         de++ Gy+k+vd+w++Gvi+ytllaGsppfwhrkq+lmlr+im+G+y+f+spewdd+s++

Q: 200   DENHSGYGKQVDMWSCGVIMYTLLAGSPPFWHRKQMLMLRMIMSGEYHFGSPEWDDRSDT  259

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         vkdli++llvv+pe+rlta+eal hpff

Q: 260   VKDLIARLLVVNPERRLTADEALIHPFF  287

         ***************************8

Domain Sequence
(FASTA)

YEPKEILGRG VSSVVRRCIF KPSREDFAVK IIDITGDHLS SEQIAELRDS TVKEIDILKK 60

VSGFPNVIQL KDSYESHTFF FLVFDLMRRG ELFDYLTEKV TLSEKETRKI MRSLLEVVSK 120

LHAYNIVHRD LKPENILLDD DMNIKLTDFG FSCQIQEGEK LKEICGTPGY LAPEILHCSM 180

DENHSGYGKQ VDMWSCGVIM YTLLAGSPPF WHRKQMLMLR MIMSGEYHFG SPEWDDRSDT 240

VKDLIARLLV VNPERRLTAD EALIHPFF 268

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

xtr:448255

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013