EKS-XET-00354

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00354

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	423.1	5.6E-127	201	487	287

Status

Unreviewed

Ensembl Protein

ENSXETP00000022801

UniProt Accession

F7AVJ1;

Protein Name

Protein Synonyms/Alias

Gene Name

acvr1c

Gene Synonyms/Alias

acvr1c;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000010381	ENSXETP00000022801	ENSXETT00000022801

Organism

Xenopus tropicalis

Functional Description

Protein Length

498

Protein Sequence
(FASTA)

NNSQGLCPFP PLLSLALSAL VTMLPLAPPS LKCVCLLCEN TNYTCQTEGA CWTSVMLTHG 60

KEEVLKSCIS LPEFKAQVFC HSSNNITRTE CCLSDFCNNI TLRLPAVTPG VSHMGHVELT 120

VIVTVSICLL SVVIMVTAYV CQERYCAKNK ARRQCVEEPL TECPLDIAGK SLKDLIYDMT 180

TSGSGSGLPL LVQRTIARTV VIQELVGKGR FGEVWRGKWC GEDVAVKIFS SRDERSWFRE 240

AEIYQTVMLR HENILGFIAA DNKDNGTWTQ LWLISEFHEQ GSLFDYLNCN TVTIGGMMKL 300

ALSVVSGLAH LHMEIVGTQG MPWYTRREGK SKNILVKKNE TCCIADLGLA VKHDSITNTI 360

DIPQNPRVGT KRYMAPELLD DSINTYHFDS FKCSDIYSLG LVYWEIARRC SVGGVVDEYQ 420

LPYYDMVPSD PSLEDVRKVV CEQKLRPSIP NQWQSFEALR IMGRIMRECW YANGKARLTA 480

LRIKKTISQL CVEEDYKL 498

Nucleotide Sequence
(FASTA)

AACAATAGCC AGGGTCTGTG CCCTTTTCCC CCATTGTTAT CCCTAGCTCT TAGTGCCCTC 60

GTCACCATGC TTCCTCTGGC ACCCCCGAGT CTGAAGTGTG TGTGCCTGCT GTGTGAGAAC 120

ACAAACTACA CGTGTCAGAC AGAAGGGGCC TGTTGGACGT CTGTGATGCT CACCCATGGG 180

AAGGAGGAGG TGCTGAAATC CTGTATCTCG CTGCCCGAGT TTAAAGCTCA GGTTTTCTGC 240

CACAGTTCAA ACAATATCAC TAGGACCGAG TGTTGCCTGT CTGATTTCTG TAACAATATA 300

ACACTCCGAC TGCCGGCAGT GACTCCGGGA GTGTCCCACA TGGGCCATGT GGAGCTGACG 360

GTGATCGTCA CTGTTTCTAT ATGCCTCTTG TCAGTAGTCA TAATGGTAAC TGCATATGTC 420

TGCCAGGAGC GCTACTGTGC TAAGAACAAA GCCCGGCGCC AATGTGTTGA GGAGCCTCTT 480

ACAGAATGCC CCCTGGATAT TGCTGGGAAA TCACTAAAAG ACCTTATTTA TGACATGACT 540

ACTTCTGGAT CTGGGTCAGG TTTGCCTCTG CTGGTCCAAA GGACTATTGC AAGGACTGTT 600

GTCATTCAGG AACTTGTTGG CAAGGGACGA TTTGGGGAAG TTTGGCGTGG AAAGTGGTGC 660

GGGGAAGATG TGGCTGTAAA GATCTTCTCC TCTAGGGATG AAAGGTCCTG GTTCCGGGAG 720

GCAGAGATAT ATCAGACGGT TATGCTAAGG CATGAAAATA TCCTTGGCTT TATTGCTGCT 780

GATAATAAAG ATAATGGCAC TTGGACCCAG CTGTGGCTTA TATCGGAATT CCATGAACAG 840

GGCTCCTTGT TTGATTATTT AAACTGCAAC ACTGTAACTA TAGGCGGAAT GATGAAACTG 900

GCGTTGTCTG TAGTCAGTGG GCTGGCTCAC CTACACATGG AAATTGTTGG TACTCAAGGT 960

ATGCCATGGT ATACGAGGAG GGAAGGAAAG TCCAAAAATA TTCTAGTGAA GAAGAACGAG 1020

ACGTGTTGCA TTGCAGATCT AGGTCTGGCG GTCAAACATG ATTCCATAAC TAATACAATA 1080

GATATCCCTC AGAATCCTAG GGTAGGGACC AAAAGGTATA TGGCTCCGGA ATTGCTGGAC 1140

GATTCAATAA ACACATATCA CTTTGACTCG TTCAAATGCT CAGACATCTA TTCCCTTGGC 1200

CTGGTGTACT GGGAGATCGC CAGGAGATGT TCCGTGGGAG GAGTTGTTGA TGAATACCAG 1260

TTGCCTTATT ATGACATGGT GCCTTCGGAC CCTTCTTTGG AAGACGTGAG GAAGGTGGTC 1320

TGTGAGCAGA AGTTGCGACC CAGCATACCA AACCAGTGGC AGAGTTTTGA AGCTCTGCGA 1380

ATCATGGGCA GAATAATGCG GGAATGTTGG TACGCCAACG GCAAGGCCCG GCTGACCGCC 1440

CTCCGCATCA AGAAGACCAT CTCTCAGCTT TGTGTGGAGG AGGATTACAA GCTGTAA 1497

Domain Profile

S: 2     klleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfiaa  61

          ++el+gkGr+geVw++k+ ge+vAvKifs++de+sw+rE+eiyqtv+lrhenil+fiaa

Q: 201   VIQELVGKGRFGEVWRGKWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAA  260

         5789********************************************************

S: 62    dkkeedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtkg  121

         d+k+++++t+l+l++e+he+gsL+dyL+ +t+++  +++lals++sGlahLH+eivgt+g

Q: 261   DNKDNGTWTQLWLISEFHEQGSLFDYLNCNTVTIGGMMKLALSVVSGLAHLHMEIVGTQG  320

         ************************************************************

S: 122   kkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekeeldlaansqvGtkRYmaPEv  181

            p  + R+ kskNilvkk++tcciaDlGLa+k+++ ++++d+ +n +vGtkRYmaPE+

Q: 321   --MPWYTRREGKSKNILVKKNETCCIADLGLAVKHDSITNTIDIPQNPRVGTKRYMAPEL  378

         ..99********************************************************

S: 182   leealnlkdfeafkraDvYslgLvlWEvasRceevdeeveeyklpfeevvgsdPsleemk  241

         l++++n+ +f++fk+ D+YslgLv+WE+a+Rc+  +++v+ey+lp++++v+sdPsle+++

Q: 379   LDDSINTYHFDSFKCSDIYSLGLVYWEIARRCSV-GGVVDEYQLPYYDMVPSDPSLEDVR  437

         *********************************9.*************************

S: 242   evvvekklrPkipeawkkkealkelsklleecWdadpeaRltalrvkkrl  291

         +vv+e+klrP+ip++w++ eal+ + ++++ecW+a+++aRltalr+kk++

Q: 438   KVVCEQKLRPSIPNQWQSFEALRIMGRIMRECWYANGKARLTALRIKKTI  487

         ***********************************************986

Domain Sequence
(FASTA)

VIQELVGKGR FGEVWRGKWC GEDVAVKIFS SRDERSWFRE AEIYQTVMLR HENILGFIAA 60

DNKDNGTWTQ LWLISEFHEQ GSLFDYLNCN TVTIGGMMKL ALSVVSGLAH LHMEIVGTQG 120

MPWYTRREGK SKNILVKKNE TCCIADLGLA VKHDSITNTI DIPQNPRVGT KRYMAPELLD 180

DSINTYHFDS FKCSDIYSLG LVYWEIARRC SVGGVVDEYQ LPYYDMVPSD PSLEDVRKVV 240

CEQKLRPSIP NQWQSFEALR IMGRIMRECW YANGKARLTA LRIKKTI 287

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

InterPros

IPR000472	; Activin_rcpt.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR003605	; TGF_beta_rcpt_GS.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.
PF08515	; TGF_beta_GS; 1.

SMARTs

SM00467

; GS; 1.

Prosites

PS51256	; GS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013