EKS-XET-00320

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00320

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	338.9	1.9E-101	16	269	254

Status

Unreviewed

Ensembl Protein

ENSXETP00000024367

UniProt Accession

F6R539;

Protein Name

Protein Synonyms/Alias

Gene Name

prkaa2

Gene Synonyms/Alias

prkaa2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000011138	ENSXETP00000062540	ENSXETT00000066254
ENSXETG00000011138	ENSXETP00000024367	ENSXETT00000024367

Organism

Xenopus tropicalis

Functional Description

Protein Length

552

Protein Sequence
(FASTA)

MAEKQKHDGR VKIGHYILGD TLGVGTFGKV KRLGEHQLTG HKVAVKILNR QKIRNLDVVG 60

KIKREIQNLK LFRHPHIIKL YQVISTPTDF FMVMEYVSGG ELFDYICKHG RVEEAEARRL 120

FQQIISAVDY CHRHMVVHRD LKPENVLLDA HMNAKIADFG LSNMMSDGEF LRTSCGSPNY 180

AAPEVISGRL YAGPEVDIWS CGVILYALLC GTLPFDDEHV PTLFKKIRGG VFYIPEYLNR 240

SAATLLMHML QVDPLKRATI KDIREHEWFK QDLPSYLFPE DPSYDANVID DEAVKEVCEK 300

FECTESEVMN SLYSGDPQDQ LAVAYHLIID NRRIMNQASE FYLASSPPTG SFIDESTLHI 360

PPGVKPHPER MPPLIADSPK ARCPLDALNT TKPKPLAVKK AKWHLGIRSQ SKPYDIMAEV 420

YRAMKQLDFE WKVVNPYHLR VRRKNPVTGT YVKMSLQLYQ VDNRSYLLDF KSIDDEVMEQ 480

KSGSSTPQRS CSAAGLHRPR LSIDSSTSDY SAPSGPLFGS FSGSFSLVNP RLGSHTMDFF 540

EMCASLITTL AR 552

Nucleotide Sequence
(FASTA)

ATGGCTGAGA AGCAGAAGCA CGATGGACGG GTTAAAATAG GACACTACAT CTTGGGTGAC 60

ACGCTAGGAG TTGGCACCTT CGGAAAAGTG AAAAGGCTGG GTGAACATCA GCTAACAGGG 120

CATAAAGTTG CAGTGAAAAT ATTGAACAGA CAAAAAATTC GTAATTTGGA TGTTGTTGGC 180

AAAATAAAGA GAGAAATACA AAATCTAAAG CTTTTTCGAC ACCCTCACAT AATAAAACTG 240

TACCAAGTCA TTAGCACTCC AACAGATTTT TTCATGGTCA TGGAATACGT TTCTGGAGGA 300

GAATTGTTTG ACTATATCTG CAAACATGGA AGGGTTGAAG AAGCAGAGGC AAGACGCCTT 360

TTTCAACAGA TCATTTCTGC TGTAGATTAC TGTCACAGAC ATATGGTGGT TCACCGCGAT 420

CTGAAACCAG AGAATGTGCT GCTTGATGCA CACATGAATG CCAAGATAGC TGATTTTGGA 480

TTATCCAACA TGATGTCAGA TGGGGAATTC CTGCGGACCA GTTGTGGTTC ACCTAATTAT 540

GCAGCACCGG AAGTCATATC GGGAAGATTG TATGCAGGTC CTGAGGTTGA TATCTGGAGC 600

TGTGGAGTGA TACTCTATGC TCTTCTCTGT GGAACTCTAC CATTTGATGA TGAACATGTT 660

CCAACTCTTT TTAAGAAGAT AAGAGGAGGA GTATTTTACA TCCCTGAGTA CCTAAACCGC 720

TCTGCTGCTA CATTGTTAAT GCATATGCTT CAGGTTGACC CTCTTAAGCG TGCCACTATC 780

AAAGACATAA GAGAACATGA ATGGTTTAAA CAGGATTTAC CCAGTTACTT GTTTCCAGAA 840

GACCCGTCAT ATGATGCCAA TGTAATTGAT GATGAGGCTG TGAAGGAGGT GTGTGAGAAG 900

TTTGAATGTA CAGAATCCGA AGTTATGAAC AGTTTATACA GCGGTGACCC ACAAGACCAG 960

CTTGCTGTTG CCTACCATCT TATAATAGAC AATCGAAGAA TAATGAACCA GGCCAGTGAA 1020

TTCTACCTCG CCTCTAGTCC ACCAACTGGC TCATTCATAG ACGAAAGCAC TTTGCACATC 1080

CCACCTGGAG TGAAGCCACA CCCAGAAAGA ATGCCACCTC TAATAGCAGA TAGTCCAAAG 1140

GCAAGATGCC CTTTAGATGC TTTGAACACC ACCAAACCTA AACCCCTAGC TGTGAAAAAA 1200

GCCAAGTGGC ACTTGGGGAT CCGCAGCCAA AGTAAACCAT ATGATATTAT GGCTGAAGTT 1260

TATCGAGCTA TGAAGCAACT TGATTTTGAA TGGAAGGTAG TTAACCCTTA TCATCTCCGT 1320

GTGAGAAGAA AGAATCCAGT GACTGGTACT TATGTGAAAA TGAGTCTGCA GCTCTACCAG 1380

GTTGATAATC GCAGTTACCT TTTGGACTTC AAAAGTATTG ACGATGAAGT CATGGAACAA 1440

AAATCAGGTT CTTCAACCCC TCAACGTTCT TGCTCTGCAG CTGGCCTGCA CAGACCACGC 1500

CTGAGTATTG ACTCGAGCAC ATCAGACTAT TCAGCGCCAA GTGGACCTCT GTTTGGCTCT 1560

TTCTCAGGCA GTTTTAGTTT AGTTAACCCT CGCTTGGGGA GCCATACCAT GGATTTCTTT 1620

GAAATGTGTG CCAGTCTGAT TACAACGCTG GCTCGTTAA 1659

Domain Profile

S: 1     ykllktlGegsfgkVk.lakhketkekvavKiikkkkl.seeslekikrEieilkklkhp  58

         y l++tlG g+fgkVk l +h++t++kvavKi++++k+ + + + kikrEi+ lk ++hp

Q: 16    YILGDTLGVGTFGKVKrLGEHQLTGHKVAVKILNRQKIrNLDVVGKIKREIQNLKLFRHP  75

         8899***********8467899***************96667788***************

S: 59    niikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskg  118

         +iikl++vi+t +++++v+ey+sggeLfdyi ++gr++e ear+lf+q++sav+Y+h++

Q: 76    HIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEAEARRLFQQIISAVDYCHRHM  135

         ************************************************************

S: 119   ivHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpk  178

         +vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+

Q: 136   VVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPE  195

         ************************************************************

S: 179   vDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpe  238

         vD+Ws+Gv+Lyal++g+lPfd+e++ +l++ki  g + ip++l++++++Ll ++L+vdp

Q: 196   VDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSAATLLMHMLQVDPL  255

         ************************************************************

S: 239   kRatieeilkhewl  252

         kRati++i++hew+

Q: 256   KRATIKDIREHEWF  269

         *************7

Domain Sequence
(FASTA)

YILGDTLGVG TFGKVKRLGE HQLTGHKVAV KILNRQKIRN LDVVGKIKRE IQNLKLFRHP 60

HIIKLYQVIS TPTDFFMVME YVSGGELFDY ICKHGRVEEA EARRLFQQII SAVDYCHRHM 120

VVHRDLKPEN VLLDAHMNAK IADFGLSNMM SDGEFLRTSC GSPNYAAPEV ISGRLYAGPE 180

VDIWSCGVIL YALLCGTLPF DDEHVPTLFK KIRGGVFYIP EYLNRSAATL LMHMLQVDPL 240

KRATIKDIRE HEWF 254

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013