EKS-XET-00538

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00538

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	522.3	2.9E-157	20	277	258

Status

Unreviewed

Ensembl Protein

ENSXETP00000026450

UniProt Accession

B2GUM0;

Protein Name

Protein Synonyms/Alias

Sgk2 protein;

Gene Name

sgk2

Gene Synonyms/Alias

sgk2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000012119	ENSXETP00000026450	ENSXETT00000026450

Organism

Xenopus tropicalis

Functional Description

Protein Length

351

Protein Sequence
(FASTA)

MSSTINLGPS ANPNAKPTDF DFLKVIGKGS FGKVLLAKRK CDNNFYAVKV LQKKTILKKK 60

EQNHIMAERN VLLKNLKHPF LVGLHYSFQT AEKLYFVLDY VNGGELFLHL QRERCFLEPR 120

ARFYAAEVAC ALGYLHSQNI IYRDLKPENI LLDSQGHVVL TDFGLCKEGM EPEETTSTFC 180

GTPEYLAPEV LRKQPYDRTV DWWCLGAVLY EMLYGLPPFY SRDVSQMYDN ILSQPLQLPG 240

CKTTATCDIL RGLLHKDQRC RLGAKADFQE IKNHVFFSPI NWDDLYHKRI APPYNPNVAG 300

PGDLRHFDPE FTQEAVPSSV GRTPDLNVSS CSSSSAFLGF SYAQSDDDYL S 351

Nucleotide Sequence
(FASTA)

ATGTCCTCAA CAATAAACTT GGGGCCGTCT GCAAATCCAA ATGCCAAACC TACTGATTTC 60

GATTTCTTGA AAGTGATTGG CAAAGGAAGC TTTGGAAAGG TCCTTCTCGC CAAGCGTAAA 120

TGTGACAATA ACTTCTACGC AGTGAAGGTC CTGCAGAAGA AGACCATTCT CAAGAAAAAG 180

GAGCAAAACC ACATCATGGC CGAGAGGAAC GTCCTGCTGA AGAACCTCAA GCATCCATTC 240

CTGGTGGGGC TGCACTACTC CTTCCAGACT GCCGAGAAGC TCTACTTTGT ACTGGACTAT 300

GTCAATGGAG GGGAGCTGTT CTTACATTTA CAAAGGGAGA GATGTTTCCT AGAACCCCGT 360

GCCCGATTCT ATGCGGCAGA AGTGGCTTGT GCCTTGGGTT ATCTCCACTC CCAGAACATC 420

ATCTACAGAG ATTTAAAACC AGAAAATATC CTGCTGGACA GTCAGGGTCA TGTGGTGCTC 480

ACAGATTTCG GGCTGTGCAA GGAAGGCATG GAACCTGAGG AGACCACTAG TACTTTCTGT 540

GGAACCCCAG AGTACTTGGC CCCGGAGGTG CTCAGGAAGC AGCCGTATGA CCGTACAGTA 600

GACTGGTGGT GCCTGGGAGC AGTGCTGTAT GAGATGCTCT ATGGACTGCC CCCGTTCTAC 660

AGCCGTGATG TATCCCAGAT GTACGATAAC ATTCTGAGCC AACCACTCCA GCTCCCAGGG 720

TGCAAGACCA CAGCCACATG TGACATTCTC CGAGGGCTCC TCCATAAGGA TCAGCGATGC 780

CGCCTGGGCG CTAAGGCTGA CTTTCAAGAA ATCAAGAACC ATGTTTTCTT CAGCCCAATT 840

AACTGGGATG ACTTATATCA CAAGCGGATC GCTCCACCCT ATAACCCAAA TGTGGCTGGG 900

CCTGGAGACC TGAGACACTT TGATCCAGAG TTCACGCAGG AGGCGGTGCC CAGCTCAGTT 960

GGCCGCACCC CTGATTTGAA CGTTAGCAGT TGCAGCAGCT CCAGCGCTTT TCTGGGATTC 1020

TCCTACGCAC AGAGTGACGA TGACTACTTG AGCTGA 1056

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkvllakrk d++fyavkvlqkk+ilkkke++himaernvllkn+khp

Q: 20    FDFLKVIGKGSFGKVLLAKRKCDNNFYAVKVLQKKTILKKKEQNHIMAERNVLLKNLKHP  79

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqtaeklyfvldyvnggelf hlqrer+fleprarfyaae+a+algylhs n

Q: 80    FLVGLHYSFQTAEKLYFVLDYVNGGELFLHLQRERCFLEPRARFYAAEVACALGYLHSQN  139

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         i+yrdlkpenillds+ghvvltdfglcke++e e+ttstfcgtpeylapevlrk+pydrt

Q: 140   IIYRDLKPENILLDSQGHVVLTDFGLCKEGMEPEETTSTFCGTPEYLAPEVLRKQPYDRT  199

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfysrdv++mydnil +plql++  ++a++++l++ll+kd++

Q: 200   VDWWCLGAVLYEMLYGLPPFYSRDVSQMYDNILSQPLQLPGCKTTATCDILRGLLHKDQR  259

         ************************************************************

S: 241   krlgakedfleiknhvff  258

          rlgak+df eiknhvff

Q: 260   CRLGAKADFQEIKNHVFF  277

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVLLAKR KCDNNFYAVK VLQKKTILKK KEQNHIMAER NVLLKNLKHP 60

FLVGLHYSFQ TAEKLYFVLD YVNGGELFLH LQRERCFLEP RARFYAAEVA CALGYLHSQN 120

IIYRDLKPEN ILLDSQGHVV LTDFGLCKEG MEPEETTSTF CGTPEYLAPE VLRKQPYDRT 180

VDWWCLGAVL YEMLYGLPPF YSRDVSQMYD NILSQPLQLP GCKTTATCDI LRGLLHKDQR 240

CRLGAKADFQ EIKNHVFF 258

Keyword

ATP-binding; Kinase; Nucleotide-binding; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013