EKS-XET-00315

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00315

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	390.6	3.0E-117	56	307	252

Status

Unreviewed

Ensembl Protein

ENSXETP00000027898

UniProt Accession

F6ZJY0;

Protein Name

Protein Synonyms/Alias

Gene Name

mark3

Gene Synonyms/Alias

mark3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000012767	ENSXETP00000027898	ENSXETT00000027898

Organism

Xenopus tropicalis

Functional Description

Protein Length

793

Protein Sequence
(FASTA)

MSTRTPLPTV NERDTENHTS HGDGRQDVLS RSGRQGARSR NSIASCADEQ PHIGNYRLLK 60

TIGKGNFAKV KLARHILTGR EVAIKIIDKT QLNPTSLQKL FREVRIMKIL NHPNIVKLFE 120

VIETEKTLYL VMEYASGGEV FDYLVAHGRM KEKEARAKFR QIVSAVQYCH QKHIVHRDLK 180

AENLLLDADM NIKIADFGFS NEFTVGNKLD TFCGSPPYAA PELFQGKKYD GPEVDVWSLG 240

VILYTLVSGS LPFDGQNLKE LRERVLRGKY RIPFYMSTDC ENLLKRFLVL NPSKRGTLEQ 300

IMKDRWINAG HEEDELKPFV EPELDISDQK RIDIMVGMGY SREEIQESLS KMKYDEITAT 360

YLLLGRKSSE LDASDSSSSS NLSLAKVRPN SDLNNSSGQS PHHKGRSISS SQKQRRYSDH 420

AGPAVPSVTA YPKRSQTSTT DNDLKDEVGQ SRKSSSTGRG VTPPSPMLGN ASNPNKADIP 480

ERKKSSVVPT SNSTSSGMTR RNTYVCSERA PTDRHSVIQN GKENSLTGIF TYATSPASVC 540

AISSIFARLR HPKSMSMSAS RHSEMLPPIA SEGDNFGPAT IPDQRTSVAS THSITSTTTP 600

DRMRFPRGTA SRSTFHGQLR ERRTATYNGP PASPSLSHEA TPLSQTRSRG STNLFSKLTS 660

KLTRSDKSEK GSPGKTKTSR NVSGDQKDEN KESKPRSLRF TWSMKTTSSM DPNDMMREIR 720

KVLDANNCDY EQRERFLLFC VHGDGHAENL VQWEMEVCKL PRLSLNGVRF KRISGTSIAF 780

KNIASKIANE LKL 793

Nucleotide Sequence
(FASTA)

ATGTCCACAC GAACCCCACT ACCCACGGTG AATGAACGGG ACACAGAGAA TCACACTTCT 60

CATGGAGATG GACGGCAAGA TGTACTCTCC CGCTCTGGGC GTCAGGGAGC TCGCTCTAGA 120

AATTCAATTG CATCATGTGC AGATGAACAA CCACATATTG GGAATTATCG ACTTCTTAAA 180

ACAATAGGCA AAGGAAATTT TGCTAAAGTT AAACTTGCCC GGCACATCCT CACTGGTAGA 240

GAGGTGGCAA TAAAGATAAT TGATAAAACT CAGTTAAACC CCACAAGTCT ACAAAAGCTT 300

TTCAGGGAGG TAAGAATAAT GAAGATTTTG AATCATCCAA ATATAGTTAA ATTATTTGAA 360

GTAATTGAAA CAGAAAAAAC ACTCTATTTG GTGATGGAGT ATGCAAGTGG AGGTGAAGTT 420

TTTGACTACT TGGTTGCACA TGGAAGAATG AAGGAAAAAG AAGCAAGAGC TAAATTTCGC 480

CAGATAGTGT CTGCTGTGCA GTATTGTCAC CAAAAACATA TTGTTCACAG AGATCTCAAG 540

GCAGAAAATC TTCTACTGGA TGCAGATATG AACATTAAAA TAGCTGATTT TGGCTTTAGC 600

AATGAATTTA CTGTTGGCAA CAAACTGGAC ACTTTTTGTG GTAGCCCTCC ATATGCTGCT 660

CCAGAACTCT TCCAAGGAAA GAAATATGAT GGTCCTGAAG TAGATGTTTG GAGTCTTGGT 720

GTTATTCTTT ATACCCTAGT AAGTGGATCT TTACCCTTCG ATGGACAAAA TTTAAAGGAA 780

TTAAGGGAAC GAGTATTAAG GGGGAAATAC AGAATTCCTT TTTACATGTC AACAGACTGT 840

GAAAACCTTC TCAAGCGCTT CCTAGTTCTG AACCCAAGCA AAAGAGGCAC TCTAGAGCAA 900

ATAATGAAGG ACAGATGGAT CAATGCAGGA CATGAAGAGG ATGAACTGAA ACCATTTGTG 960

GAGCCTGAAC TAGATATTTC AGATCAGAAG AGAATTGACA TCATGGTAGG AATGGGATAT 1020

TCTAGAGAAG AGATCCAAGA ATCCCTTAGC AAGATGAAAT ATGATGAAAT CACCGCAACG 1080

TATTTGCTTC TTGGGCGGAA ATCATCAGAG CTGGATGCAA GTGATTCAAG TTCTAGCAGT 1140

AACCTGTCAC TTGCAAAAGT CAGGCCGAAC AGTGATTTAA ACAACAGCAG TGGACAATCC 1200

CCTCATCACA AAGGACGCAG TATCTCATCC AGCCAAAAAC AGAGACGGTA CAGTGACCAT 1260

GCTGGTCCTG CAGTTCCTTC CGTTACCGCC TACCCAAAAC GAAGTCAAAC TAGTACAACG 1320

GACAATGATC TCAAAGACGA AGTTGGGCAG TCTAGAAAAT CAAGCAGCAC TGGAAGAGGA 1380

GTGACGCCAC CTAGTCCCAT GCTTGGAAAT GCCAGTAATC CAAATAAGGC AGATATCCCA 1440

GAGCGAAAAA AGAGTTCTGT TGTTCCCACT AGTAATTCCA CATCCAGTGG CATGACACGT 1500

CGGAATACCT ATGTTTGCAG CGAGCGAGCT CCTACAGACC GCCATTCAGT CATTCAGAAT 1560

GGCAAAGAAA ACAGCCTGAC AGGAATTTTC ACTTATGCAA CTAGTCCTGC ATCAGTTTGT 1620

GCCATATCTT CCATCTTTGC CCGGCTGCGG CATCCGAAGT CGATGTCCAT GTCAGCCTCC 1680

AGGCACTCCG AGATGTTACC ACCAATAGCC AGTGAAGGGG ATAACTTCGG GCCTGCCACA 1740

ATTCCAGATC AAAGGACTTC AGTGGCATCA ACTCACAGCA TAACAAGCAC CACTACCCCA 1800

GACCGCATGC GTTTCCCAAG AGGAACAGCC AGCCGCAGCA CTTTTCATGG GCAGCTCAGA 1860

GAGCGGCGCA CAGCTACTTA TAATGGACCA CCTGCTTCCC CCAGTTTATC CCATGAAGCA 1920

ACACCTCTGT CACAGACTCG AAGTAGAGGT TCCACTAATC TTTTTAGTAA ATTAACTTCA 1980

AAATTAACTA GAAGCGATAA GAGTGAAAAG GGAAGTCCAG GGAAAACCAA AACAAGTCGT 2040

AATGTGTCAG GGGACCAGAA AGATGAAAAC AAAGAATCCA AGCCGCGATC GCTGCGTTTT 2100

ACTTGGAGCA TGAAAACCAC CAGTTCCATG GATCCCAACG ACATGATGCG CGAGATCCGC 2160

AAGGTTTTGG ACGCCAACAA TTGTGACTAT GAGCAGCGGG AACGGTTCTT ACTTTTCTGC 2220

GTCCACGGGG ACGGTCATGC GGAAAACCTT GTGCAGTGGG AGATGGAAGT GTGCAAACTG 2280

CCAAGACTCT CCCTAAATGG CGTTCGCTTT AAGCGAATAT CTGGGACATC CATAGCTTTC 2340

AAAAACATTG CTTCCAAAAT TGCCAACGAG TTAAAGCTGT AA 2382

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y+llkt+G+g+f+kVkla+h +t+++va+Kii+k++l+ +sl+k++rE++i+k+l+hpni

Q: 56    YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI  115

         99**********************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         +kl+eviet+k+lylv+eyasgge+fdy++++gr+kekear+ f+q+vsav+Y+h+k+iv

Q: 116   VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKHIV  175

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvD  180

         HrDlK+eNllld+++nikiaDFG++n+f+ g++l+tfcGsppYaaPel++gkkY+gp+vD

Q: 176   HRDLKAENLLLDADMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVD  235

         ************************************************************

S: 181   vWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekR  240

         vWslGv+Ly+lv+g+lPfd++nlkel+e++l+gk++ip+++s+++e+Ll+++Lv +p+kR

Q: 236   VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPSKR  295

         ************************************************************

S: 241   atieeilkhewl  252

          t+e+i+k++w+

Q: 296   GTLEQIMKDRWI  307

         ***********7

Domain Sequence
(FASTA)

YRLLKTIGKG NFAKVKLARH ILTGREVAIK IIDKTQLNPT SLQKLFREVR IMKILNHPNI 60

VKLFEVIETE KTLYLVMEYA SGGEVFDYLV AHGRMKEKEA RAKFRQIVSA VQYCHQKHIV 120

HRDLKAENLL LDADMNIKIA DFGFSNEFTV GNKLDTFCGS PPYAAPELFQ GKKYDGPEVD 180

VWSLGVILYT LVSGSLPFDG QNLKELRERV LRGKYRIPFY MSTDCENLLK RFLVLNPSKR 240

GTLEQIMKDR WI 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR001772	; Kinase-assoc_KA1.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.
IPR015940	; UBA/transl_elong_EF1B_N_euk.

Pfam

PF02149	; KA1; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220	; S_TKc; 1.
SM00165	; UBA; 1.

Prosites

PS50032	; KA1; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50030	; UBA; 1.

Prints

Created Date

20-Feb-2013