EKS-XET-00040

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00040

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/VRK	403.3	4.3E-121	37	303	267

Status

Unreviewed

Ensembl Protein

ENSXETP00000030474

UniProt Accession

Q6P8D6;

Protein Name

Protein Synonyms/Alias

Putative uncharacterized protein MGC75762;

Gene Name

vrk1

Gene Synonyms/Alias

vrk1; MGC75762;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000013948	ENSXETP00000030474	ENSXETT00000030474

Organism

Xenopus tropicalis

Functional Description

Protein Length

410

Protein Sequence
(FASTA)

MPPKKAASGA RKAPAKRKLA EEFPAGEVLT DSAKKQWKLG LPIGQGGFGR LYLADENSSR 60

TVGPDAPYVI KVEPSENGPL FSELKFYMRA AKPDQIQKWS TSHKLKYLGV PRYWGSGLHT 120

KNGNSYRFMV MDRFGQDLQK IFENQGKIFP RKTVLQLGLR LIDILEYIHE HEYVHGDIKA 180

SNLLIHHKNP DQVFLVDYGL AYRYCPDSVH KEYKEDPRKC HNGTIEFTSI DAHKGVSPSR 240

RGDLEILGYC MIQWLCGRLP WEDNLGDANY VTNSKIRYGD DSSELMEACF PGKNKPEEIR 300

KFMEAVKELS YTTKPPYPHL REILLQGLKT IGSKDDGKLD FSLCENGAVS HNGRKRKLAK 360

VTDHSAEESE EPNLADQKKK ARGRAAKASG SPTAPAPKGR GRGRGKKSSS 410

Nucleotide Sequence
(FASTA)

ATGCCACCCA AAAAAGCAGC GTCAGGAGCC AGAAAGGCCC CAGCTAAAAG AAAGTTGGCT 60

GAAGAGTTTC CTGCAGGGGA AGTGCTAACA GATTCAGCAA AAAAGCAATG GAAATTGGGG 120

TTACCTATTG GACAGGGTGG ATTTGGCCGT CTTTATCTTG CGGATGAAAA TTCTTCTAGA 180

ACTGTAGGAC CAGATGCTCC GTATGTCATT AAAGTAGAAC CAAGTGAGAA TGGACCACTT 240

TTCTCTGAAC TTAAGTTCTA CATGCGTGCT GCAAAACCTG ACCAGATTCA GAAGTGGAGC 300

ACCTCTCATA AACTGAAATA CTTGGGTGTG CCCAGATACT GGGGCTCTGG TCTGCATACC 360

AAAAATGGAA ACAGTTACAG GTTTATGGTA ATGGATCGTT TTGGTCAAGA CTTGCAGAAG 420

ATTTTTGAAA ACCAAGGAAA AATCTTTCCA CGTAAAACGG TTTTACAGTT AGGTTTAAGA 480

CTGATTGACA TTCTGGAGTA TATTCACGAA CATGAATATG TACATGGAGA TATCAAAGCA 540

TCAAATCTTT TGATTCACCA TAAAAATCCA GATCAGGTGT TTTTGGTAGA TTATGGTCTT 600

GCCTACAGGT ATTGTCCAGA CAGTGTTCAC AAAGAGTACA AAGAAGACCC CAGAAAATGT 660

CATAATGGCA CAATTGAATT TACAAGTATT GATGCCCACA AAGGAGTCAG TCCTTCAAGA 720

AGAGGAGACT TGGAAATATT GGGTTATTGT ATGATTCAGT GGTTGTGTGG CAGGCTGCCC 780

TGGGAAGATA ATCTCGGTGA TGCTAATTAT GTCACCAATT CTAAAATAAG GTATGGTGAT 840

GATAGTTCAG AACTTATGGA AGCCTGTTTT CCTGGTAAAA ATAAGCCAGA GGAAATTAGG 900

AAGTTCATGG AAGCAGTTAA AGAACTGTCT TATACTACAA AACCTCCATA TCCGCACTTA 960

AGAGAGATAC TTTTACAAGG CCTTAAAACC ATTGGCAGTA AAGATGATGG GAAACTGGAC 1020

TTCTCTCTTT GTGAGAATGG AGCCGTTTCT CACAATGGAC GAAAGAGAAA GCTGGCTAAG 1080

GTAACAGACC ATAGTGCAGA AGAGTCGGAA GAACCGAACC TTGCAGATCA AAAGAAGAAG 1140

GCAAGAGGGC GTGCTGCAAA AGCCAGTGGC AGTCCTACTG CACCTGCACC AAAAGGAAGG 1200

GGGCGTGGAA GAGGGAAAAA AAGTAGCTCC TGA 1233

Domain Profile

S: 1     wklgkkigkggfGeiyla..ltckkeekdaklvvkvepkenGpLfvelkfyqraakkeqi  58

         wklg +ig+ggfG++yla  +++++++ da +v+kvep+enGpLf+elkfy+raak++qi

Q: 37    WKLGLPIGQGGFGRLYLAdeNSSRTVGPDAPYVIKVEPSENGPLFSELKFYMRAAKPDQI  96

         9*****************99999*************************************

S: 59    kkwkkkkklkllgiPtliasGlhefegekyRflvlprlgrdLqklleqngkrlsektvlq  118

         +kw   +klk+lg+P +++sGlh+++g++yRf+v++r+g+dLqk+ e++gk + +ktvlq

Q: 97    QKWSTSHKLKYLGVPRYWGSGLHTKNGNSYRFMVMDRFGQDLQKIFENQGKIFPRKTVLQ  156

         ************************************************************

S: 119   lavrlldvleylHeneYvHgdikAanllleeeeasqvyLvdyGlayrycpegkhkeyked  178

         l++rl+d+ley+He+eYvHgdikA+nll+++++++qv+LvdyGlayrycp+++hkeyked

Q: 157   LGLRLIDILEYIHEHEYVHGDIKASNLLIHHKNPDQVFLVDYGLAYRYCPDSVHKEYKED  216

         ************************************************************

S: 179   krraHdGtleftslDaHkGvapsrRsDleiLgYcllkWltgkLPWeallkdpekvqkake  238

         +r++H+Gt+efts+DaHkGv+psrR+DleiLgYc+++Wl+g LPWe++l d ++v+++k

Q: 217   PRKCHNGTIEFTSIDAHKGVSPSRRGDLEILGYCMIQWLCGRLPWEDNLGDANYVTNSKI  276

         ************************************************************

S: 239   kfldelpellkkllkkkssseelakyl  265

         ++ d+ +el++ +++ k+++ee++k++

Q: 277   RYGDDSSELMEACFPGKNKPEEIRKFM  303

         *************************97

Domain Sequence
(FASTA)

WKLGLPIGQG GFGRLYLADE NSSRTVGPDA PYVIKVEPSE NGPLFSELKF YMRAAKPDQI 60

QKWSTSHKLK YLGVPRYWGS GLHTKNGNSY RFMVMDRFGQ DLQKIFENQG KIFPRKTVLQ 120

LGLRLIDILE YIHEHEYVHG DIKASNLLIH HKNPDQVFLV DYGLAYRYCP DSVHKEYKED 180

PRKCHNGTIE FTSIDAHKGV SPSRRGDLEI LGYCMIQWLC GRLPWEDNLG DANYVTNSKI 240

RYGDDSSELM EACFPGKNKP EEIRKFM 267

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>