EKS-XET-00529

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00529

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/DAPK	396.1	6.8E-119	57	317	261

Status

Unreviewed

Ensembl Protein

ENSXETP00000016605

UniProt Accession

F6Q411;

Protein Name

Protein Synonyms/Alias

Gene Name

stk17a

Gene Synonyms/Alias

stk17a;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000015813	ENSXETP00000016605	ENSXETT00000016605

Organism

Xenopus tropicalis

Functional Description

Protein Length

419

Protein Sequence
(FASTA)

MVPEEGFGVP DKCCRTPRAA RRPKRDEESS NDRAGLLGEP SIPIRSQPFS SAYSISPGHE 60

LGRGKFAVVR KCVEKETGKE FAAKFMRKRR KGQDCRMEII HEIAVLELAR GSPWVIKLHE 120

VYETATEMIL VLEYAAGGEI FNQCVAEREE AFKEKDVRRL MRQILKGVAF LHRHNVVHLD 180

LKPQNVLLTS ACPLGDIKVV DFGLSRILNN NEELREIMGT PEYVDLAPEI LSYEPISTAT 240

DMWSVGVLAY VMLTGTSPFL GDDKQQTFLN ISQLNVTYSS EEFDGISDSA IDFIKALLIR 300

KPEARSSAVD CLQHPWLAQG DLPDPYASAM NSVQESNHVT QEEENAEDEL TQAMSPEPVT 360

SIPEAEGQTV AEELIVMASY TLGQCRQTEL EKQSESKATT KRFKFEEPIM QEITGDFIF 419

Nucleotide Sequence
(FASTA)

ATGGTCCCGG AGGAGGGTTT CGGGGTGCCG GACAAGTGCT GTCGCACCCC CCGAGCGGCG 60

AGGAGGCCAA AGCGAGACGA GGAGAGCAGT AATGATAGAG CCGGGCTACT GGGGGAGCCG 120

AGCATCCCTA TCCGGAGCCA GCCCTTCAGC AGCGCCTACA GCATCTCCCC GGGGCATGAG 180

CTGGGCAGAG GCAAATTTGC AGTGGTAAGA AAATGTGTGG AAAAGGAGAC TGGCAAAGAA 240

TTTGCAGCAA AATTTATGAG AAAACGAAGA AAGGGCCAGG ACTGTCGTAT GGAAATCATT 300

CATGAAATTG CTGTTTTGGA GTTGGCTAGG GGCAGCCCTT GGGTTATCAA ACTGCATGAA 360

GTCTACGAGA CTGCCACTGA AATGATCCTA GTGCTGGAAT ATGCTGCTGG CGGTGAGATA 420

TTCAACCAGT GTGTAGCAGA AAGGGAAGAG GCCTTCAAAG AGAAAGATGT CCGGAGGCTG 480

ATGAGGCAGA TATTAAAAGG AGTCGCCTTT CTGCACCGGC ACAATGTAGT TCATCTAGAC 540

TTGAAGCCCC AGAATGTTCT CCTGACGAGT GCTTGTCCTC TTGGGGACAT AAAGGTAGTG 600

GACTTTGGCT TGTCAAGAAT ATTAAATAAC AATGAGGAGC TAAGAGAAAT TATGGGGACC 660

CCAGAATATG TTGATTTAGC TCCTGAAATT CTAAGTTATG AGCCCATCAG CACTGCAACA 720

GACATGTGGA GTGTTGGTGT CCTGGCATAT GTCATGCTAA CAGGCACCTC CCCTTTCTTG 780

GGAGATGACA AACAACAAAC CTTCCTAAAT ATTTCCCAGC TGAATGTAAC TTACAGTAGT 840

GAGGAATTTG ATGGTATTTC TGATTCTGCC ATTGATTTCA TCAAAGCACT TCTCATTCGC 900

AAGCCTGAAG CTCGTTCTTC AGCTGTTGAC TGTCTCCAAC ATCCATGGCT AGCCCAAGGG 960

GACCTTCCTG ATCCCTATGC TAGTGCTATG AACTCTGTGC AAGAAAGCAA CCATGTCACA 1020

CAGGAAGAGG AGAATGCAGA GGATGAACTA ACTCAGGCAA TGTCTCCAGA GCCGGTCACA 1080

TCCATTCCAG AGGCAGAAGG ACAGACTGTA GCAGAAGAAC TGATTGTAAT GGCATCTTAT 1140

ACATTGGGAC AGTGCCGGCA GACTGAATTA GAGAAGCAAT CTGAATCTAA GGCCACTACC 1200

AAACGCTTTA AGTTTGAGGA GCCTATAATG CAAGAGATAA CAGGAGACTT CATCTTCTAA 1260

Domain Profile

S: 3     tgkelgsGkfavvrkcrekstGkeyaakflkkrrlkssrrgvsreeierevavlkeirse  62

          g+elg+Gkfavvrkc ek+tGke+aakf++krr    +++++r+ei +e+avl+++r++

Q: 57    PGHELGRGKFAVVRKCVEKETGKEFAAKFMRKRR----KGQDCRMEIIHEIAVLELARGS  112

         5789******************************....**********************

S: 63    pnvinlhevyenksdvililelvaGGelfd..llaekeslseeeatellkqilegvkylh  120

         p+vi+lhevye+++++il+le++aGGe+f+  +++++e+++e+++++l++qil+gv +lh

Q: 113   PWVIKLHEVYETATEMILVLEYAAGGEIFNqcVAEREEAFKEKDVRRLMRQILKGVAFLH  172

         ******************************988899************************

S: 121   skkivhldlkPenillldkkvpkgdiklidfGlsrkieegaelkeilGtPefv..aPeiv  178

          +++vhldlkP+n+ll++   p gdik++dfGlsr +++ +el+ei+GtPe+v  aPei+

Q: 173   RHNVVHLDLKPQNVLLTSAC-PLGDIKVVDFGLSRILNNNEELREIMGTPEYVdlAPEIL  231

         *****************998.*******************************7779****

S: 179   nyeplsletdmwsiGvityillsgasPflGdtkqetllnisavnldfseelfssvselak  238

         +yep+s++tdmws+Gv++y++l+g+sPflGd+kq+t+lnis++n+++s e f+ +s++a+

Q: 232   SYEPISTATDMWSVGVLAYVMLTGTSPFLGDDKQQTFLNISQLNVTYSSEEFDGISDSAI  291

         ************************************************************

S: 239   dfirrllvkdpekrltieeclehswl  264

         dfi+ ll+++pe r ++ +cl+h+wl

Q: 292   DFIKALLIRKPEARSSAVDCLQHPWL  317

         *************************7

Domain Sequence
(FASTA)

PGHELGRGKF AVVRKCVEKE TGKEFAAKFM RKRRKGQDCR MEIIHEIAVL ELARGSPWVI 60

KLHEVYETAT EMILVLEYAA GGEIFNQCVA EREEAFKEKD VRRLMRQILK GVAFLHRHNV 120

VHLDLKPQNV LLTSACPLGD IKVVDFGLSR ILNNNEELRE IMGTPEYVDL APEILSYEPI 180

STATDMWSVG VLAYVMLTGT SPFLGDDKQQ TFLNISQLNV TYSSEEFDGI SDSAIDFIKA 240

LLIRKPEARS SAVDCLQHPW L 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013