EKS-XET-00229

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00229

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	493.3	2.2E-148	4	284	281

Status

Unreviewed

Ensembl Protein

ENSXETP00000034865

UniProt Accession

F6YAB3;

Protein Name

Protein Synonyms/Alias

Gene Name

ick

Gene Synonyms/Alias

ick;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000015974	ENSXETP00000034865	ENSXETT00000034865

Organism

Xenopus tropicalis

Functional Description

Protein Length

625

Protein Sequence
(FASTA)

MNRYTTVKQL GDGTYGSVIL GRSVESGELV AIKKMKRKFY SWDECMNLRE VKSLKKLNHA 60

NVIKLKEVIR ENNQLYFVFE YMKENLYQLM KDRNKLFPES IIRNIMYQIL QGLAYIHKYG 120

FFHRDLKPEN LLCMGPELVK IADFGLARET RSRPPYTDYV STRWYRAPEV LLRATNYNSP 180

IDIWAVGCIM AEIYTLRPLF PGSSEVDTIF KICQVLGTPK KNDWFEGFQL ASAMNFRWAH 240

CVPSNLKTLI PNACADGIQV MRDMLQWDPK KRPTASQALR YSYFQVGQTL GTSPRIHELS 300

KQQKEPHEKQ ISLQIKPVPP TRPPPKHRLP SRAFQPSQPY ANPFKQSPSW TEPFSLSQEK 360

DKVGQPHLPA LSTRVPQKAA SDTESANGEL NLKTRRRWGH VTKTIKGSDE WDDSDDDVHF 420

SNPRTEIKQN EKQNEDAVHS FKSIVDLKNA DNGSAGSELN SFAQQDSATS RRASAAKQHY 480

LKHSRYLPGL TINNSAGKSS SSDSTNVSNP WPIPLQPIKP LGLASETNSR LSGLQGQKGS 540

SDPVSSYLPA FLKKDIGYIG QKVQLAPLTD PTPNYGSLRS VGSFLGPPSF RSPSKGTQRL 600

TSKPAPPVFP VHGRTDWLSK YGGHR 625

Nucleotide Sequence
(FASTA)

ATGAATCGAT ATACAACAGT CAAACAACTT GGAGATGGAA CATATGGCTC TGTCATTCTT 60

GGGAGGAGTG TGGAATCAGG AGAGCTTGTG GCCATTAAGA AAATGAAAAG GAAATTCTAC 120

TCCTGGGATG AATGCATGAA TCTTCGTGAA GTAAAGTCGC TGAAGAAACT GAATCATGCA 180

AATGTCATAA AGCTAAAGGA AGTCATAAGA GAAAATAACC AACTCTACTT TGTTTTTGAG 240

TATATGAAGG AAAATCTCTA CCAGCTAATG AAAGATCGGA ACAAATTATT TCCGGAATCT 300

ATTATCAGGA ATATTATGTA CCAAATTCTT CAAGGGCTTG CATATATACA CAAATACGGG 360

TTTTTTCACA GAGACTTAAA ACCTGAGAAC CTCCTTTGCA TGGGACCTGA ACTTGTGAAA 420

ATTGCAGATT TTGGACTAGC TCGAGAAACT AGATCAAGGC CACCATACAC TGATTATGTG 480

TCAACCAGAT GGTATAGAGC TCCTGAGGTT CTCCTTAGAG CCACAAACTA TAACTCCCCT 540

ATAGATATTT GGGCAGTTGG CTGTATCATG GCTGAAATTT ACACACTTAG GCCACTTTTT 600

CCAGGCTCCA GCGAAGTTGA TACCATTTTC AAAATTTGTC AAGTGCTGGG AACTCCAAAG 660

AAGAATGATT GGTTTGAAGG TTTCCAGCTT GCTTCTGCAA TGAATTTTCG CTGGGCCCAT 720

TGTGTACCCA GCAACCTAAA AACCTTGATT CCAAATGCTT GTGCAGATGG GATCCAAGTC 780

ATGCGAGACA TGCTACAGTG GGATCCCAAG AAGAGGCCAA CTGCAAGCCA AGCTCTTCGG 840

TATTCTTACT TTCAAGTAGG ACAGACGCTA GGAACATCAC CTCGAATACA TGAGTTGTCC 900

AAACAGCAAA AAGAACCTCA TGAAAAACAA ATTTCGCTTC AAATCAAACC TGTGCCTCCA 960

ACTCGGCCAC CACCAAAGCA TCGACTGCCA TCACGAGCAT TTCAGCCAAG TCAACCATAT 1020

GCCAATCCTT TTAAACAAAG TCCATCCTGG ACCGAGCCAT TCAGTCTTTC TCAAGAGAAG 1080

GACAAAGTGG GTCAACCACA TCTGCCTGCA TTAAGTACCA GAGTACCACA GAAAGCCGCC 1140

TCTGATACAG AGAGTGCCAA TGGGGAGCTG AATTTAAAGA CCAGAAGAAG ATGGGGTCAT 1200

GTTACTAAAA CAATCAAGGG ATCTGATGAA TGGGATGACT CCGATGACGA TGTCCATTTT 1260

TCAAATCCTA GAACTGAGAT TAAACAGAAT GAAAAACAAA ATGAGGATGC AGTCCACAGC 1320

TTTAAAAGTA TAGTGGATTT AAAGAATGCA GACAATGGTT CTGCTGGGTC AGAACTCAAC 1380

TCGTTCGCTC AGCAAGATTC TGCTACTTCC AGAAGAGCCT CGGCAGCAAA ACAACATTAC 1440

TTAAAGCACT CCCGCTATTT GCCTGGTCTT ACTATCAACA ACAGTGCAGG CAAATCCTCA 1500

AGCAGTGATT CTACAAATGT TTCAAATCCG TGGCCAATTC CTCTTCAGCC CATTAAGCCA 1560

CTGGGCTTGG CATCTGAGAC CAATAGCAGG CTTTCAGGTC TTCAAGGTCA GAAAGGAAGC 1620

AGTGACCCAG TTTCTAGTTA TCTGCCAGCC TTTTTGAAAA AAGATATTGG CTATATTGGG 1680

CAGAAGGTGC AGTTAGCTCC ACTTACAGAT CCAACTCCCA ATTATGGATC CCTGAGGTCT 1740

GTTGGATCAT TTCTTGGTCC GCCTTCTTTT CGTTCACCTT CCAAAGGCAC ACAGAGGCTG 1800

ACATCCAAAC CAGCACCTCC TGTGTTTCCA GTTCATGGAA GAACAGACTG GCTTTCCAAA 1860

TATGGAGGGC ACAGA 1875

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++k+lGdGt+g+v+l++s+++gelvaikkmkrkf+s++e++nlrevkslkkln h+n+

Q: 4     YTTVKQLGDGTYGSVILGRSVESGELVAIKKMKRKFYSWDECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         iklkevi  ren++ly+v+e+m+enlyql+kdr+kl++es +++i+yqil+gla+ihk g

Q: 63    IKLKEVI--RENNQLYFVFEYMKENLYQLMKDRNKLFPESIIRNIMYQILQGLAYIHKYG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrdlkPen+l++g+elvk+adfGlare rs++PytdyvstrwyraPevllr ++y+sp

Q: 121   FFHRDLKPENLLCMGPELVKIADFGLARETRSRPPYTDYVSTRWYRAPEVLLRATNYNSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavGc++ae+++lrplfPG+se+d+ifki++vlGtPkk++w e+++lasa+n+++ +

Q: 181   IDIWAVGCIMAEIYTLRPLFPGSSEVDTIFKICQVLGTPKKNDWFEGFQLASAMNFRWAH  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++s+lktl++na  +++++++d+l++dP++r+ta+qal+y yf

Q: 241   CVPSNLKTLIPNACADGIQVMRDMLQWDPKKRPTASQALRYSYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTVKQLGDG TYGSVILGRS VESGELVAIK KMKRKFYSWD ECMNLREVKS LKKLNHANVI 60

KLKEVIRENN QLYFVFEYMK ENLYQLMKDR NKLFPESIIR NIMYQILQGL AYIHKYGFFH 120

RDLKPENLLC MGPELVKIAD FGLARETRSR PPYTDYVSTR WYRAPEVLLR ATNYNSPIDI 180

WAVGCIMAEI YTLRPLFPGS SEVDTIFKIC QVLGTPKKND WFEGFQLASA MNFRWAHCVP 240

SNLKTLIPNA CADGIQVMRD MLQWDPKKRP TASQALRYSY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013