EKS-XET-00140

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00140

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	508.4	6.3E-153	89	383	295

Status

Unreviewed

Ensembl Protein

ENSXETP00000036273

UniProt Accession

F6V346;

Protein Name

Protein Synonyms/Alias

Gene Name

stk38

Gene Synonyms/Alias

stk38;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000016625	ENSXETP00000036273	ENSXETT00000036273

Organism

Xenopus tropicalis

Functional Description

Protein Length

466

Protein Sequence
(FASTA)

MAMTEQTPCI SMSNHTKERV TMTKMTLENF YSNLITQHEE RELRQKRLEK AMDEEGLRDE 60

EKRMRRSAHA RKETEFLRLK RTRLGLEDFE SLKVIGRGAF GEVRLVQKKD TGHVYAMKIL 120

RKTDMLEKEQ VGHIRAERDI LVEADSLWVV KMFYSFQDKL NLYLIMEFLP GGDMMTLLMK 180

KDTLTEEETQ FYIAETVLAI DSIHQLGFIH RDIKPDNLLL DSKKGHVKLS DFGLCTGLKK 240

AHRTDFYRNL NHSLPSDFNF QNMNSKRKAE TWKRNRRQLA FSTVGTPDYI APEVFLQTGY 300

NKLCDWWSLG VIMYEMLIGY PPFCSETPQE TYKKVMNWKE TLIFPPEVPI SEKAKDLILR 360

FCCEWEQRVG APGVEEIKTN HFFEGVDWEH IRERPAAIPI EIKSIDDTSN FDEFPDSDIL 420

KPMGAVSNHP ESEFKNKDWV FINYTYKRFE GLTARGALPS FIKPRK 466

Nucleotide Sequence
(FASTA)

ATGGCAATGA CAGAGCAAAC TCCATGCATC TCAATGAGTA ACCATACAAA GGAGCGGGTC 60

ACAATGACCA AAATGACATT AGAAAACTTT TACAGTAACC TCATCACACA GCATGAGGAA 120

CGGGAGCTTC GGCAGAAGAG ACTGGAAAAA GCAATGGATG AGGAAGGATT GAGGGATGAA 180

GAGAAAAGGA TGCGAAGGTC AGCTCATGCA AGAAAAGAAA CAGAGTTTCT AAGACTAAAA 240

AGGACAAGAC TGGGACTGGA GGATTTTGAA TCCTTAAAAG TAATAGGAAG AGGTGCATTT 300

GGAGAGGTGA GGCTGGTTCA AAAGAAAGAC ACAGGGCATG TCTATGCGAT GAAGATATTA 360

CGGAAGACTG ATATGCTTGA AAAAGAGCAG GTTGGACACA TCCGTGCAGA ACGAGATATT 420

CTAGTGGAGG CTGACAGCTT GTGGGTGGTG AAAATGTTCT ACAGCTTTCA GGACAAACTA 480

AACCTTTATC TTATCATGGA ATTTCTGCCA GGAGGTGATA TGATGACATT GCTGATGAAG 540

AAAGACACTC TGACGGAAGA GGAAACACAG TTTTACATTG CAGAGACTGT ACTGGCAATT 600

GATTCTATCC ATCAGCTTGG ATTTATCCAC AGAGATATTA AGCCTGATAA CCTTCTCCTG 660

GACAGCAAGA AGGGACATGT AAAGCTTTCA GATTTTGGGT TATGTACGGG ACTTAAGAAG 720

GCCCATCGGA CTGATTTCTA CAGGAACTTG AACCACAGCC TGCCAAGTGA TTTCAATTTT 780

CAGAATATGA ATTCTAAGAG GAAAGCGGAA ACATGGAAAA GAAACAGACG TCAACTGGCA 840

TTTTCCACTG TTGGAACACC AGACTATATA GCACCTGAAG TATTTCTCCA AACTGGATAC 900

AACAAGTTGT GTGATTGGTG GTCATTAGGT GTCATCATGT ATGAGATGTT AATTGGTTAT 960

CCTCCGTTTT GTTCTGAAAC ACCGCAGGAA ACATACAAAA AAGTCATGAA CTGGAAGGAG 1020

ACGCTGATAT TTCCACCTGA GGTCCCAATT TCAGAAAAAG CCAAGGATCT TATTTTACGC 1080

TTCTGCTGTG AATGGGAGCA GAGAGTTGGT GCTCCGGGTG TAGAAGAGAT CAAAACTAAC 1140

CATTTCTTTG AAGGTGTTGA CTGGGAACAT ATTAGGGAAA GGCCTGCTGC TATTCCTATT 1200

GAAATAAAAA GCATTGATGA TACATCAAAT TTTGATGAAT TTCCTGATTC TGATATTCTC 1260

AAACCAATGG GAGCTGTAAG CAACCATCCT GAATCGGAGT TCAAGAACAA GGACTGGGTC 1320

TTTATCAACT ACACATACAA GCGCTTTGAA GGGCTTACAG CAAGGGGGGC TCTTCCATCT 1380

TTCATTAAAC CAAGGAAGTG A 1401

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt++vya+kilrk+d+l+k+qv h++aerdil+eads w

Q: 89    FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKTDMLEKEQVGHIRAERDILVEADSLW  148

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk nlyl+me+lPGGd+mtll+kk++l+ee+++fyiae+vla++s+h+lGf

Q: 149   VVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGF  208

         ************************************************************

S: 121   ihrdlkPdnllida.kGhikltdfGlctGlkkthrseyykelekakeddleaseelkvle  179

         ihrd+kPdnll+d+ kGh+kl+dfGlctGlkk+hr+++y++l+++ ++d+++++  ++ +

Q: 209   IHRDIKPDNLLLDSkKGHVKLSDFGLCTGLKKAHRTDFYRNLNHSLPSDFNFQNMNSKRK  268

         *************637**********************************6666555555

S: 180   rrkkkknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPflaetp  239

             k+nrr+la+s+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++etp

Q: 269   AETWKRNRRQLAFSTVGTPDYIAPEVFLQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETP  328

         5555********************************************************

S: 240   qetykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         qetykkv+nwketl fp+ev++se+akdli r+++++e+r+g+ Gv+eik++ ff

Q: 329   QETYKKVMNWKETLIFPPEVPISEKAKDLILRFCCEWEQRVGAPGVEEIKTNHFF  383

         ****************************************************998

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHVYAMK ILRKTDMLEK EQVGHIRAER DILVEADSLW 60

VVKMFYSFQD KLNLYLIMEF LPGGDMMTLL MKKDTLTEEE TQFYIAETVL AIDSIHQLGF 120

IHRDIKPDNL LLDSKKGHVK LSDFGLCTGL KKAHRTDFYR NLNHSLPSDF NFQNMNSKRK 180

AETWKRNRRQ LAFSTVGTPD YIAPEVFLQT GYNKLCDWWS LGVIMYEMLI GYPPFCSETP 240

QETYKKVMNW KETLIFPPEV PISEKAKDLI LRFCCEWEQR VGAPGVEEIK TNHFF 295

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013