EPS-XET-00017

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-XET-00017

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	65.8	4.0E-18	139	292	154

Status

Unreviewed

Ensembl Protein

ENSXETP00000038390

UniProt Accession

B3DL33;

Protein Name

Protein Synonyms/Alias

LOC100170449 protein;

Gene Name

epm2a

Gene Synonyms/Alias

epm2a; LOC100170449;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000017691	ENSXETP00000038390	ENSXETT00000038390

Organism

Xenopus tropicalis

Functional Description

Protein Length

313

Protein Sequence
(FASTA)

MLFRFGVIIT LNHSDNELLV LGSRKEMGSW DPQYAVPMKP TRCPLSTTEP SFWVGEVLLE 60

EPYTDTFWFK FIKKESGALI WEGNGPHHDR CCVFNESNIV DGVYCHPVGH WIETTGHTDE 120

MKHTTDFYFH FAGTQAMHFS RILPNIWLGS CPRQREHVTV KMKHELGVTA VLNFQTEWDV 180

IQNSSGCNNY PEPMSPETMF RLYKEAGITY IWIPTPDMST EGRIRMLPQA VYLLFGLLEN 240

GHTVYVHCNA GVGRSTAAVC GFLMYVIGWS LRKVQYFLAS RRPAVYIDEE AMINAQEDFH 300

KKFGHLRSTV CRI 313

Nucleotide Sequence
(FASTA)

ATGCTTTTTC GTTTTGGAGT GATAATTACT TTGAACCACT CAGATAATGA GCTTCTTGTA 60

CTGGGATCTC GAAAGGAAAT GGGAAGCTGG GACCCACAGT ATGCTGTACC AATGAAGCCT 120

ACTCGTTGTC CGCTGTCTAC CACAGAACCA TCCTTTTGGG TAGGGGAGGT GCTGCTAGAG 180

GAACCCTACA CTGACACCTT CTGGTTTAAG TTCATCAAGA AAGAGTCAGG AGCTTTAATT 240

TGGGAAGGGA ATGGCCCTCA TCATGATCGT TGCTGTGTTT TTAATGAGAG TAATATAGTG 300

GATGGTGTTT ATTGCCATCC CGTAGGACAT TGGATTGAAA CCACAGGGCA TACCGATGAG 360

ATGAAGCACA CAACAGACTT CTACTTCCAT TTTGCAGGCA CTCAGGCCAT GCATTTCTCC 420

AGAATCCTAC CAAACATTTG GCTTGGAAGT TGCCCACGGC AACGGGAACA TGTGACTGTG 480

AAGATGAAGC ATGAATTAGG AGTTACAGCT GTGCTGAACT TCCAGACTGA ATGGGATGTC 540

ATTCAGAATT CTAGCGGCTG CAACAACTAT CCTGAGCCCA TGAGTCCTGA AACAATGTTC 600

CGGTTATATA AAGAAGCTGG AATAACATAT ATTTGGATTC CTACTCCTGA TATGAGCACA 660

GAAGGCAGAA TCCGGATGTT ACCACAAGCA GTTTATCTCC TTTTTGGGTT ATTAGAAAAT 720

GGTCACACTG TCTATGTTCA TTGCAATGCT GGTGTTGGCA GATCGACAGC TGCAGTCTGC 780

GGATTCCTCA TGTATGTGAT TGGATGGAGC CTTCGGAAAG TACAGTATTT CCTTGCGTCA 840

CGGAGACCTG CTGTCTATAT AGATGAAGAA GCTATGATTA ATGCTCAAGA AGACTTTCAT 900

AAAAAATTTG GACACCTTCG TTCCACTGTG TGTCGAATAT AG 942

Domain Profile

S: 2     vteilpglylgdqataldrreLs...klgitvvinasls..vik....vq.....viPe.  46

          ++ilp+++lg+     ++++++   +lg+t v+n  ++  vi+    ++       Pe

Q: 139   FSRILPNIWLGSCPRQREHVTVKmkhELGVTAVLNFQTEwdVIQnssgCNnypepMSPEt  198

         579999999999888888877642226789999987654112221111331111123552

S: 47    ...ylikkgityknipvdDsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatl  103

            ++ + gity  ip  D  ++  ++++++a+ ++    e+g+ v+vHC+aGv+RS++

Q: 199   mfrLYKEAGITYIWIPTPDMSTEGRIRMLPQAVYLLFGLLENGHTVYVHCNAGVGRSTAA  258

         222456789***************************************************

S: 104   vlaYLmkveglslsdAieavkrkrpsiepnegfl  137

         v+++Lm+v g+sl+++   + ++rp+++ +e+ +

Q: 259   VCGFLMYVIGWSLRKVQYFLASRRPAVYIDEEAM  292

         *****************************99987

Domain Sequence
(FASTA)

FSRILPNIWL GSCPRQREHV TVKMKHELGV TAVLNFQTEW DVIQNSSGCN NYPEPMSPET 60

MFRLYKEAGI TYIWIPTPDM STEGRIRMLP QAVYLLFGLL ENGHTVYVHC NAGVGRSTAA 120

VCGFLMYVIG WSLRKVQYFL ASRRPAVYID EEAM 154

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:2001070	; F:starch binding
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

xtr:100170449

;

InterPros

IPR013784	; Carb-bd-like_fold.
IPR002044	; CBM_fam20.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR013783	; Ig-like_fold.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00686	; CBM_20; 1.
PF00782	; DSPc; 1.

SMARTs

SM01065

; CBM_2; 1.

Prosites

PS51166	; CBM20; 1.
PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

Created Date

20-Feb-2013