EKS-XET-00536

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00536

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	298.7	3.7E-89	103	351	249

Status

Unreviewed

Ensembl Protein

ENSXETP00000039781

UniProt Accession

F6V613;

Protein Name

Protein Synonyms/Alias

Gene Name

pkmyt1

Gene Synonyms/Alias

pkmyt1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000018363	ENSXETP00000039781	ENSXETT00000039781

Organism

Xenopus tropicalis

Functional Description

Protein Length

551

Protein Sequence
(FASTA)

MPVPGDDMGD TPLTRTPIPV PAHFSQAEQS FSLKKRGRSL CYTLPPRPPV KSALPISRLF 60

PNKQRSWSQP RPQSVSFRSP QNNPPASELY DQSKGETFFK QCFRSICKLG RGSFGEVYKV 120

QSLEDGCFYA VKRSVSPFRG ESDRQRKLQE VRKHERVGVH PNCLRFVRAW EEKRLLYLQT 180

ELCAGSLQQH SEEFSGPLPP RKIWNITCDL LHGLKHLHDR NLLHLDIKPA NVFISFSGVC 240

KLGDFGLMVE LDGTEGSGEA QEGDPRYMAP ELLDGIFSKA ADVFSLGMSL LEVACNMELP 300

KSGDGWQQLR QGRLPTEFTS DLPPDFLKVL AAMLEPDYRR RATVDWLLSL PAIRNAERWR 360

MVTLAQERTL GKIITVYQFI VWLVSIVFQG LNRPVVGFLH YCGLRALPRS PPCSPSPNLG 420

ESSFSSDWDD ESLGDDVFEV PPSPLAAHRN FTYHGQELIG SIRHSPDLLS RPSLGSTSTP 480

RNLSPEFSMR KRSALPLTPN VSRISQESSG SVKSTSPSTS HSSSGFVDAE VQRSSFLPRN 540

LLSMFDDATE Q 551

Nucleotide Sequence
(FASTA)

ATGCCTGTTC CAGGAGATGA CATGGGAGAT ACTCCCCTTA CTCGCACCCC TATCCCTGTG 60

CCTGCTCACT TCAGTCAGGC AGAGCAAAGC TTTTCACTTA AAAAAAGAGG GCGCTCCCTT 120

TGCTATACCC TGCCACCCAG ACCTCCAGTT AAGAGCGCTC TGCCTATTAG CCGCCTATTC 180

CCGAACAAAC AGCGGTCTTG GAGCCAGCCT AGGCCACAAA GTGTTTCTTT CCGAAGTCCC 240

CAGAACAATC CCCCTGCAAG CGAGCTCTAT GACCAGAGCA AAGGAGAGAC CTTTTTCAAG 300

CAGTGTTTTA GAAGCATTTG CAAATTAGGC CGAGGATCCT TTGGCGAGGT ATACAAGGTG 360

CAAAGCCTTG AGGATGGATG CTTCTATGCC GTGAAGCGCT CAGTTTCTCC TTTCCGTGGC 420

GAGTCAGACC GCCAACGGAA GCTTCAGGAG GTGAGGAAGC ATGAGAGAGT CGGGGTGCAC 480

CCCAACTGCC TGCGTTTTGT GCGAGCATGG GAAGAGAAAC GATTGCTCTA CCTGCAGACG 540

GAGTTATGTG CAGGGAGTCT GCAACAGCAC TCGGAAGAAT TTTCTGGGCC CCTCCCTCCA 600

CGTAAAATAT GGAACATAAC TTGTGACCTG TTGCACGGTC TCAAACATCT TCATGATCGC 660

AACCTTCTGC ACCTTGACAT TAAACCAGCT AACGTCTTCA TTTCATTTTC TGGTGTTTGC 720

AAACTGGGTG ACTTTGGACT CATGGTAGAA TTAGATGGAA CCGAAGGAAG TGGAGAAGCG 780

CAGGAAGGTG ACCCTCGATA CATGGCACCT GAACTCTTGG ATGGGATCTT TTCGAAGGCC 840

GCTGATGTGT TCAGCCTTGG AATGAGTCTT CTAGAGGTCG CTTGCAATAT GGAGCTTCCA 900

AAAAGTGGAG ACGGCTGGCA GCAGCTAAGA CAAGGGCGTC TCCCTACAGA GTTCACATCA 960

GACCTGCCGC CAGACTTTCT GAAAGTTCTT GCTGCAATGC TGGAGCCTGA CTACCGCCGG 1020

CGTGCCACAG TGGACTGGCT GCTCTCCCTT CCTGCTATCC GTAATGCAGA GAGATGGAGG 1080

ATGGTGACAC TAGCTCAGGA AAGGACACTT GGAAAGATAA TTACAGTCTA TCAGTTCATC 1140

GTTTGGCTTG TATCTATCGT GTTTCAAGGT CTCAACCGCC CAGTTGTAGG ATTTTTACAT 1200

TACTGTGGAT TAAGAGCACT TCCAAGGTCC CCTCCCTGTT CTCCTTCTCC CAACCTAGGG 1260

GAGAGCAGCT TCTCTAGTGA CTGGGATGAT GAGAGTCTTG GTGACGATGT GTTTGAGGTT 1320

CCACCCAGCC CATTGGCCGC TCACCGGAAC TTTACATACC ATGGGCAGGA GCTTATTGGC 1380

AGCATAAGAC ATTCCCCAGA CCTGCTCTCA AGACCATCAC TTGGAAGCAC CTCTACCCCT 1440

CGGAATTTGT CTCCTGAATT CAGCATGAGA AAGAGGTCTG CTTTGCCTCT AACTCCTAAT 1500

GTCAGCCGGA TTAGTCAGGA GTCTTCAGGC AGTGTGAAGT CTACTAGCCC CTCCACCAGT 1560

CATAGTTCCT CTGGATTTGT CGATGCCGAG GTCCAACGTT CTTCATTTCT CCCTCGCAAT 1620

CTGCTCAGCA TGTTTGACGA TGCCACCGAG CAATGA 1656

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F ++ k+G+G+fgev+kv++ edg+ yA+k+s +p++g+s+++++l+Ev++h+ +g h+n

Q: 103   FRSICKLGRGSFGEVYKVQSLEDGCFYAVKRSVSPFRGESDRQRKLQEVRKHERVGVHPN  162

         77889*******************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         ++r+++aWee+  ly+qtElC  gsL+++    e+ +  l+  ++++i  dll+gl++lH

Q: 163   CLRFVRAWEEKRLLYLQTELC-AGSLQQH---SEEFSGPLPPRKIWNITCDLLHGLKHLH  218

         *********************.9******...5566779*********************

S: 121   ssslvHlDikpenifitkevtlklgDlGlvtel.nsedkskveEGDsrylakEilqeeys  179

         +++l+HlDikp+n+fi++++++klgD+Gl++el ++e + +++EGD ry+a+E+l++ +s

Q: 219   DRNLLHLDIKPANVFISFSGVCKLGDFGLMVELdGTEGSGEAQEGDPRYMAPELLDGIFS  278

         *********************************5578899********************

S: 180   klkaDiFslgltilevaanvelPsnGeaWhklRkgklpdeilkelsedlrellklmlepd  239

         k+ aD+Fslg+++leva+n+elP+ G+ W++lR+g+lp e+++ l  d+ ++l+ mlepd

Q: 279   KA-ADVFSLGMSLLEVACNMELPKSGDGWQQLRQGRLPTEFTSDLPPDFLKVLAAMLEPD  337

         **.*********************************************************

S: 240   perRptaeellkhe  253

         ++rR+t + ll+ +

Q: 338   YRRRATVDWLLSLP  351

         *******9999876

Domain Sequence
(FASTA)

FRSICKLGRG SFGEVYKVQS LEDGCFYAVK RSVSPFRGES DRQRKLQEVR KHERVGVHPN 60

CLRFVRAWEE KRLLYLQTEL CAGSLQQHSE EFSGPLPPRK IWNITCDLLH GLKHLHDRNL 120

LHLDIKPANV FISFSGVCKL GDFGLMVELD GTEGSGEAQE GDPRYMAPEL LDGIFSKAAD 180

VFSLGMSLLE VACNMELPKS GDGWQQLRQG RLPTEFTSDL PPDFLKVLAA MLEPDYRRRA 240

TVDWLLSLP 249

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007049	; P:cell cycle

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.
IPR016235	; Tyr/Thr_kinase_Cdc2_inhib.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013