EKS-XET-00104

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00104

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PSK	509.4	2.0E-153	90	347	258

Status

Unreviewed

Ensembl Protein

ENSXETP00000039981

UniProt Accession

Q28FC8;

Protein Name

Protein Synonyms/Alias

Protein serine kinase H1;

Gene Name

pskh1

Gene Synonyms/Alias

pskh1; TEgg079e04.1-001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000018464	ENSXETP00000039981	ENSXETT00000039981

Organism

Xenopus tropicalis

Functional Description

Protein Length

416

Protein Sequence
(FASTA)

MGCGTSKVLP EPSKNLQQDL VKKVEPCLDR KSDQYNNCIT DKSQTFLKDD YLSHSLPNGD 60

LKCHVESAHL RRHKIAKYRA KFDPRVTAKY DIKALIGRGS FSRVVRVEHK ASKQPYAIKM 120

IETKCREGRE VCESELNVLR RVRHTNIIQL IEVFESQERV YMVMELATGG ELFDRIITKG 180

SFTERDATHV LQMVLEGVKY LHALGITHRD LKPENLLYYH PGIDSKIMIT DFGLASAQKK 240

GDDCLMKTTC GTPEYIAPEV LVRKPYTNSV DMWALGVISY ILLSGTMPFE DDNRTRLYRQ 300

ILRGKYSYSG EPWPSVSNLA KDFIDRLLMV EPGQRMTATH ALKHPWIVSM AASSSMKNLH 360

RSISQNLLKR ASSRCQSTKS SQSIHSSRST KSSKSRRVRE RELRELNLRY QQHYNG 416

Nucleotide Sequence
(FASTA)

ATGGGTTGTG GGACAAGCAA AGTTCTCCCT GAACCTTCAA AAAACCTCCA GCAGGACTTG 60

GTGAAAAAAG TGGAACCTTG TTTGGACAGA AAAAGTGACC AATATAATAA TTGTATTACA 120

GACAAAAGCC AGACATTTCT AAAGGATGAT TACCTATCTC ACTCACTGCC TAATGGAGAC 180

TTGAAGTGTC ATGTGGAAAG TGCACATTTA AGGAGACACA AAATTGCTAA GTACAGGGCC 240

AAGTTTGACC CACGTGTAAC TGCAAAATAT GATATAAAAG CTCTTATTGG ACGAGGTAGT 300

TTTAGTCGTG TTGTAAGAGT AGAACATAAG GCCTCTAAAC AGCCATATGC TATTAAAATG 360

ATTGAAACTA AATGCAGGGA AGGAAGGGAG GTATGTGAAT CTGAACTTAA TGTTTTGAGG 420

CGAGTTCGAC ATACCAATAT TATTCAACTG ATTGAAGTAT TTGAGTCACA GGAAAGGGTT 480

TATATGGTCA TGGAGCTTGC AACAGGTGGT GAACTTTTCG ATCGTATAAT CACCAAAGGC 540

TCATTCACTG AAAGGGATGC CACTCATGTA TTACAGATGG TTTTGGAAGG TGTGAAATAT 600

CTGCATGCAC TAGGCATCAC TCACAGAGAT CTAAAACCTG AAAACCTGCT TTACTATCAT 660

CCAGGTATTG ACTCCAAAAT AATGATAACA GATTTTGGAC TTGCAAGTGC TCAAAAAAAA 720

GGGGATGACT GTTTGATGAA GACAACCTGT GGAACACCAG AATATATTGC ACCAGAAGTT 780

TTAGTAAGAA AGCCCTACAC CAACTCTGTA GACATGTGGG CTCTTGGAGT CATTTCTTAT 840

ATTCTTCTAA GTGGAACTAT GCCATTTGAA GATGATAACA GGACCAGGTT ATACAGGCAA 900

ATTCTGAGAG GGAAATACAG CTATTCTGGA GAGCCATGGC CAAGTGTCTC AAATCTGGCT 960

AAAGACTTCA TTGATCGCCT TTTGATGGTG GAACCAGGAC AGCGGATGAC AGCCACACAT 1020

GCTCTTAAGC ATCCATGGAT AGTAAGCATG GCAGCTTCTT CATCAATGAA AAATCTGCAT 1080

CGCTCTATTT CACAAAACTT GCTAAAAAGA GCATCTTCTC GCTGCCAGAG CACAAAATCT 1140

TCACAATCGA TCCATTCTAG TCGGTCTACT AAGTCTAGTA AATCACGGCG AGTGAGAGAA 1200

CGTGAGCTTC GAGAGTTGAA TTTGCGTTAC CAGCAGCATT ACAATGGCTG A 1251

Domain Profile

S: 1     ydikaligkgsfsrvvrvehratrkpfaikvvetkeregreaveselrvlrrvshafiiq  60

         ydikalig+gsfsrvvrveh+a+++p+aik++etk regre++esel+vlrrv+h++iiq

Q: 90    YDIKALIGRGSFSRVVRVEHKASKQPYAIKMIETKCREGREVCESELNVLRRVRHTNIIQ  149

         9***********************************************************

S: 61    lvevfeteekvylvmelatggelfdrviakgsfterdatrvlkmvldgvrylhalrithr  120

         l+evfe++e+vy+vmelatggelfdr+i+kgsfterdat+vl+mvl+gv+ylhal+ithr

Q: 150   LIEVFESQERVYMVMELATGGELFDRIITKGSFTERDATHVLQMVLEGVKYLHALGITHR  209

         ************************************************************

S: 121   dlkpenllyydpgeeskilitdfglayaakksddllmkttcgtpeyiapevllrkpytns  180

         dlkpenllyy+pg +ski+itdfgla+a+kk+dd+lmkttcgtpeyiapevl+rkpytns

Q: 210   DLKPENLLYYHPGIDSKIMITDFGLASAQKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNS  269

         ************************************************************

S: 181   vdmwalgviayillsgilpfdddsrtrlyrkilkgkysylgepwpsvselakdfidklle  240

         vdmwalgvi+yillsg++pf+dd+rtrlyr+il+gkysy+gepwpsvs+lakdfid+ll+

Q: 270   VDMWALGVISYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLM  329

         ************************************************************

S: 241   vdagerlsasqalkhewv  258

         v++g+r++a++alkh+w+

Q: 330   VEPGQRMTATHALKHPWI  347

         *****************7

Domain Sequence
(FASTA)

YDIKALIGRG SFSRVVRVEH KASKQPYAIK MIETKCREGR EVCESELNVL RRVRHTNIIQ 60

LIEVFESQER VYMVMELATG GELFDRIITK GSFTERDATH VLQMVLEGVK YLHALGITHR 120

DLKPENLLYY HPGIDSKIMI TDFGLASAQK KGDDCLMKTT CGTPEYIAPE VLVRKPYTNS 180

VDMWALGVIS YILLSGTMPF EDDNRTRLYR QILRGKYSYS GEPWPSVSNL AKDFIDRLLM 240

VEPGQRMTAT HALKHPWI 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

xtr:549784

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013