EKS-XET-00402

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00402

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	302.3	3.3E-90	27	293	267

Status

Unreviewed

Ensembl Protein

ENSXETP00000040867

UniProt Accession

F6T9A2;

Protein Name

Protein Synonyms/Alias

Gene Name

myo3b

Gene Synonyms/Alias

myo3b;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000018850	ENSXETP00000040867	ENSXETT00000040867

Organism

Xenopus tropicalis

Functional Description

Protein Length

1321

Protein Sequence
(FASTA)

RKSFFGFFPY NHNMLGLESL ADPSDTWDII DTIGKGTYGK VYKVSNKTDG SLAAVKILDP 60

VSDLDEEIEA EYNILRSLPN HPNVVMFFGM FYKADQYIGG QLWLVLELCN GGSVTDLVKS 120

ILKCGQRLDE MIISYILYGA LLGLQHLHNN RIIHRDVKGN NILLTTEGGV KLVDFGVSAQ 180

LTSARLRRNT SVGTPFWMAP EVIACEQQYD YSYDVRCDVW SLGITAIELA DGDPPLSDMH 240

PVKALFKIPR NPPPTLLNPG KWCRGFSHFI SQCLIKDFEK RPSVIHLLEH PFIKQVHGKD 300

MALQRQLAKL IQVQQQSGSI AKTRYERMHT KRPYVLQTKE NSCLDDDLVN LEVLDEDTII 360

HQLQTRYADL QIYTYVGDIL IALNPFQNLS IYSPQFSKLY HGVKRASNPP HIFASADAAY 420

QGMVTFCKDQ CIIISGESGA GKTESAHLIV QHLTFLGKAN NRALREKILQ VNPLVEAFGN 480

ACTVINDNSS RFGKYLEMMF TPTGAVMGAK ISEYLLEKSR VIKQAVGEKN FHIFYYIYAG 540

LHHHKKLSEY RLPEKKPPSY INNETGTVMQ DIVNNESYRR QFAAIQHCFR IIGFSNEEVH 600

SVYRILAGIL NTGNIEFTAI SSKHQIDKSE VPNGEALENA ASLLSIGSEE LQEALTSHCV 660

VTRGETIIRT NTVDKAADVR DAMSKALYGR LFSWIVNRIN TLLQPDKNIC NAESGMNVGI 720

LDIFGFENFK RNSFLLYIRP LASRQLTVFH GLTLKMQNME YQSEGIDAAL VKYEDNRPLL 780

DTFLQKPMGL LSLLDEESRF PQATDQTLVD KFEDNLRCKY FWRPKGVELC FGIQHYAGKV 840

LYNVCGFLEK NRDTLPADIV VVLRTSENKL LQQLFSSPLT KTGNLAQSRA RVTAASRSLP 900

PQLNAGRIKV DTMEMMRHPG ETTNMKRQTV ASYFRYSLMD LLSKMVVGQP HFVRCIKPND 960

DRQAIKFCRE RVLMQLRYTG ILETVNIRRQ GYSHRILFDE FLKRYYYLAF KAHQNPPGTR 1020

ETCTAILEKA KLDKWVLGKT KVFLKYYHVE QLNLLLREVI GRVVVMQAYT KGWLGARRYK 1080

KVKEKREKSA TSIQTAWRGY DARRKYQQLR ARRDEAAVCI QSGNVDNKIN GFIKSMATGM 1140

KGKNELRFCT ETGSEHRVLR RQARHRYGSQ STSSDGEAQV NMHASVDGKG PRSAEQESKH 1200

GKDPSPRSYK LGGSSTDMVY FCIFYPAAMQ LIIFLRGSPK KQWSDGCLEK KLRTARRRCQ 1260

QPKTLNSPED SMYYNQVNGS LEYQGSKRKP RKLGQVKLLD GEDEYYKLLS AADSIPEEDF 1320

S 1321

Nucleotide Sequence
(FASTA)

AGGAAGTCTT TCTTTGGATT TTTCCCTTAT AATCACAATA TGCTTGGCCT TGAGTCCTTG 60

GCAGACCCCT CCGATACATG GGATATAATC GACACCATTG GTAAAGGTAC ATATGGCAAA 120

GTTTACAAAG TCAGCAACAA GACAGATGGC AGCCTGGCCG CGGTGAAGAT CTTGGATCCA 180

GTCAGTGATT TGGATGAAGA GATTGAGGCA GAATACAACA TATTGCGGTC GCTTCCAAAT 240

CATCCGAATG TTGTGATGTT TTTTGGAATG TTTTACAAAG CTGATCAGTA TATCGGAGGG 300

CAACTGTGGC TGGTTCTTGA GCTGTGCAAT GGCGGATCTG TTACAGACCT GGTTAAAAGC 360

ATCTTGAAGT GTGGGCAGCG CTTGGATGAA ATGATAATCT CCTACATTCT GTACGGAGCT 420

CTCTTGGGAC TTCAGCATTT GCACAACAAT AGAATCATTC ATCGTGACGT CAAAGGGAAC 480

AATATTCTCC TCACGACGGA AGGCGGAGTC AAGCTGGTTG ACTTTGGTGT TTCAGCGCAA 540

CTGACCAGCG CGCGCCTACG GAGAAACACA TCTGTGGGGA CTCCATTTTG GATGGCACCA 600

GAAGTCATTG CTTGCGAGCA GCAATACGAT TACTCCTATG ATGTGCGCTG TGACGTGTGG 660

TCCCTGGGGA TCACAGCCAT TGAACTAGCT GATGGAGACC CGCCTTTGTC TGACATGCAC 720

CCTGTCAAAG CTCTCTTCAA GATCCCCAGA AACCCACCAC CTACATTGCT TAATCCAGGA 780

AAATGGTGTC GAGGGTTCAG CCACTTCATT TCACAGTGTC TTATTAAGGA TTTTGAAAAG 840

AGGCCATCAG TCATTCATCT TCTAGAGCAT CCATTCATCA AACAAGTGCA CGGCAAAGAT 900

ATGGCTTTAC AGCGACAGCT GGCCAAACTC ATCCAGGTAC AACAGCAATC GGGATCTATA 960

GCAAAAACAA GGTACGAACG CATGCATACC AAAAGGCCTT ATGTTCTACA GACAAAGGAA 1020

AACTCTTGCC TAGATGATGA CCTGGTTAAC CTTGAAGTTC TGGATGAGGA CACTATAATA 1080

CATCAGTTAC AGACCCGATA TGCTGACTTG CAGATTTACA CCTACGTTGG GGATATATTA 1140

ATAGCTTTAA ACCCCTTCCA GAATCTCAGC ATTTACTCTC CGCAGTTTTC CAAGCTTTAC 1200

CATGGAGTCA AGCGTGCCTC AAACCCTCCC CATATATTTG CCTCAGCAGA TGCGGCGTAC 1260

CAGGGCATGG TTACCTTCTG CAAAGATCAG TGCATTATCA TCAGCGGAGA GAGCGGTGCT 1320

GGGAAGACAG AAAGTGCCCA TCTCATTGTC CAACATTTGA CCTTCCTCGG AAAGGCAAAT 1380

AACAGAGCAC TGAGAGAAAA GATTCTGCAA GTGAACCCAC TGGTTGAAGC CTTTGGCAAT 1440

GCATGTACAG TTATCAATGA CAACTCCAGC CGCTTTGGGA AATACCTGGA AATGATGTTT 1500

ACACCTACTG GAGCAGTGAT GGGTGCAAAG ATTTCAGAAT ATCTCTTGGA GAAATCAAGG 1560

GTCATCAAGC AAGCTGTAGG GGAGAAAAAT TTCCATATTT TTTATTACAT TTATGCTGGA 1620

CTGCACCATC ACAAAAAGCT GTCAGAATAC AGACTGCCGG AAAAAAAGCC GCCTAGCTAT 1680

ATCAACAATG AAACGGGGAC AGTAATGCAG GATATTGTCA ATAATGAATC GTATAGAAGG 1740

CAGTTTGCAG CAATTCAGCA TTGCTTCAGA ATCATAGGAT TCAGTAATGA GGAAGTCCAC 1800

TCAGTGTACA GAATTTTGGC TGGAATATTA AATACAGGAA ATATTGAATT TACAGCTATT 1860

TCTTCTAAAC ATCAGATTGA TAAAAGTGAG GTACCAAACG GAGAAGCCTT AGAAAATGCT 1920

GCCTCCCTTC TCAGCATTGG TTCAGAAGAA CTCCAGGAAG CGCTCACCTC CCATTGTGTA 1980

GTAACTAGAG GCGAAACCAT TATACGGACA AATACAGTGG ACAAAGCGGC TGATGTCCGG 2040

GATGCAATGT CCAAAGCTCT GTATGGCAGA CTTTTTAGCT GGATAGTTAA TAGGATCAAT 2100

ACACTTCTGC AGCCAGACAA AAATATATGT AATGCAGAAA GTGGAATGAA CGTTGGAATT 2160

CTAGATATTT TTGGATTTGA AAACTTCAAA AGGAACTCCT TTTTACTCTA TATCAGACCT 2220

CTTGCTAGCA GACAACTCAC TGTCTTTCAT GGATTAACCT TAAAAATGCA GAATATGGAA 2280

TACCAGAGTG AAGGAATCGA CGCCGCCTTG GTGAAGTACG AGGACAACCG GCCACTCTTA 2340

GATACTTTTC TCCAAAAGCC AATGGGTCTT CTGTCCCTGC TCGATGAAGA GAGCAGATTT 2400

CCACAAGCAA CTGACCAAAC TTTAGTTGAC AAATTTGAAG ATAACCTGAG ATGCAAATAC 2460

TTTTGGAGGC CAAAGGGCGT TGAGCTTTGT TTTGGCATTC AGCACTATGC TGGGAAGGTT 2520

CTGTACAACG TTTGTGGGTT TCTGGAGAAG AACAGAGACA CGCTCCCAGC TGACATCGTA 2580

GTTGTGCTGA GAACATCAGA AAACAAACTC CTCCAGCAGC TGTTCTCGAG CCCATTGACC 2640

AAAACAGGTA ACCTGGCACA ATCACGGGCA CGGGTAACAG CAGCTTCCAG GTCTTTGCCT 2700

CCTCAACTGA ATGCTGGACG TATTAAGGTA GACACCATGG AAATGATGAG ACATCCAGGG 2760

GAGACAACAA ACATGAAAAG ACAGACAGTG GCTTCTTATT TTAGGTACTC CCTAATGGAT 2820

CTCTTATCAA AAATGGTAGT TGGGCAGCCT CACTTTGTCC GCTGTATTAA GCCCAACGAT 2880

GATCGGCAGG CGATTAAATT TTGTCGGGAA AGGGTTCTCA TGCAGCTTCG TTACACTGGG 2940

ATTCTGGAGA CAGTAAATAT CCGAAGACAG GGATATTCTC ATAGGATTCT GTTTGACGAA 3000

TTTTTGAAAA GGTACTATTA TCTTGCCTTT AAAGCACATC AAAACCCACC TGGCACAAGA 3060

GAAACCTGCA CTGCAATTCT AGAGAAAGCT AAGCTAGACA AATGGGTTCT GGGGAAAACA 3120

AAGGTGTTCC TGAAATATTA CCATGTGGAG CAGCTGAACC TTCTACTGCG GGAAGTGATC 3180

GGAAGAGTGG TGGTAATGCA AGCCTATACC AAGGGGTGGC TTGGGGCAAG GAGATATAAG 3240

AAAGTAAAAG AGAAACGTGA GAAGAGTGCC ACCTCTATTC AGACAGCGTG GAGAGGCTAT 3300

GATGCACGAA GGAAATATCA ACAACTAAGA GCAAGAAGAG ATGAAGCAGC AGTTTGTATT 3360

CAATCAGGAA ATGTGGATAA TAAGATTAAT GGTTTTATTA AATCAATGGC TACTGGGATG 3420

AAAGGGAAAA ATGAACTTCG GTTCTGCACA GAGACAGGGA GTGAACACAG AGTTCTGAGA 3480

AGGCAGGCTA GGCATAGGTA TGGTAGCCAG TCGACCTCCA GTGATGGTGA AGCACAAGTC 3540

AACATGCATG CTTCTGTAGA CGGCAAGGGA CCAAGGAGTG CCGAGCAGGA GAGTAAGCAT 3600

GGAAAAGATC CATCCCCCAG GAGCTACAAA CTAGGAGGTA GTTCAACAGA TATGGTATAC 3660

TTCTGCATTT TTTACCCAGC AGCCATGCAG CTTATAATAT TCCTTAGGGG TTCACCAAAA 3720

AAACAGTGGT CAGATGGATG CCTTGAGAAG AAGCTGAGGA CAGCACGAAG ACGGTGTCAA 3780

CAGCCCAAAA CCCTGAATTC CCCTGAGGAT AGTATGTACT ACAACCAGGT CAATGGATCT 3840

CTGGAATATC AAGGGAGCAA GAGGAAGCCA AGAAAACTTG GACAAGTGAA ACTATTGGAT 3900

GGAGAGGATG AATATTACAA ATTGTTGTCA GCTGCAGATT CAATCCCTGA GGAGGATTTC 3960

TCC 3963

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkkl.khpniv  59

         ++++++igkG++gkvy+  +k+ g+l+a+k+++  + +  ee++ e+++l++l +hpn+v

Q: 27    WDIIDTIGKGTYGKVYKVSNKTDGSLAAVKILDPVS-DLDEEIEAEYNILRSLpNHPNVV  85

         78899****************************998.9999**********99356****

S: 60    eylesflk.....eeelwlvmeylagGslsdlvk..eelkselkEeqiayilrevlkaLe  112

          ++++f+k       +lwlv+e+++gGs++dlvk   ++ ++l+E  i+yil ++l +L+

Q: 86    MFFGMFYKadqyiGGQLWLVLELCNGGSVTDLVKsiLKCGQRLDEMIISYILYGALLGLQ  145

         ********88888889******************6667889*******************

S: 113   ylHskkviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaq  172

         +lH++++iHrd+k++niLlt+eg VkL+dfgv+aql++ r +r+t vgtp+wmAPEvia+

Q: 146   HLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSARLRRNTSVGTPFWMAPEVIAC  205

         ************************************************************

S: 173   e...ekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfske  229

         e   + +Yd ++D+wslGItaiela+g+pP++d++p+kal+ki++n+pp+l ++ k+++

Q: 206   EqqyDYSYDVRCDVWSLGITAIELADGDPPLSDMHPVKALFKIPRNPPPTLLNPGKWCRG  265

         9777779*****************************************************

S: 230   fkefvekclqknpekRpsasellkhkFl  257

         f++f+++cl k++ekRps+ +ll+h+F+

Q: 266   FSHFISQCLIKDFEKRPSVIHLLEHPFI  293

         ***************************7

Domain Sequence
(FASTA)

WDIIDTIGKG TYGKVYKVSN KTDGSLAAVK ILDPVSDLDE EIEAEYNILR SLPNHPNVVM 60

FFGMFYKADQ YIGGQLWLVL ELCNGGSVTD LVKSILKCGQ RLDEMIISYI LYGALLGLQH 120

LHNNRIIHRD VKGNNILLTT EGGVKLVDFG VSAQLTSARL RRNTSVGTPF WMAPEVIACE 180

QQYDYSYDVR CDVWSLGITA IELADGDPPL SDMHPVKALF KIPRNPPPTL LNPGKWCRGF 240

SHFISQCLIK DFEKRPSVIH LLEHPFI 267

Keyword

ATP-binding; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>

Gene Ontology

GO:0016459	; C:myosin complex
GO:0005524	; F:ATP binding
GO:0003774	; F:motor activity
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000048	; IQ_motif_EF-hand-BS.
IPR011009	; Kinase-like_dom.
IPR001609	; Myosin_head_motor_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00612	; IQ; 1.
PF00063	; Myosin_head; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00015	; IQ; 2.
SM00242	; MYSc; 1.
SM00220	; S_TKc; 1.

Prosites

PS50096	; IQ; 2.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00193

; MYOSINHEAVY.

Created Date

20-Feb-2013