EKS-XET-00232

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00232

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	521.2	5.7E-157	4	287	284

Status

Unreviewed

Ensembl Protein

ENSXETP00000042662

UniProt Accession

F6QN31;

Protein Name

Protein Synonyms/Alias

Gene Name

cdkl1

Gene Synonyms/Alias

cdkl1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000019709	ENSXETP00000042662	ENSXETT00000042662

Organism

Xenopus tropicalis

Functional Description

Protein Length

352

Protein Sequence
(FASTA)

MEKYEKIGKI GEGSYGVVFK CRNRDTGQIV AIKKFLESED DPVIKKIALR EIRMLKQLKH 60

PNLVNLLEVF RRKRKLHLVF EYCDHTVLHE LDKYPRGVPE HLVKSITWQT LQAVNFCHKH 120

HCIHRDVKPE NILITRHSVI KLCDFGFARL LTGPSDYYTD YVATRWYRAP ELLVGDTQYG 180

PPVDVWAIGC VFAELLSGIP LWPGKSDVDQ LYLIRKSQGD LIARHQQVFS TNQFFSGVSI 240

PDPENMEPLE LRFPNISSQA LGLMKGCLHM DPAKRLACQQ LLDHPYFDSI RDEGDGVTDS 300

ERLSRKQTRL HRKYIPGLQH LPQLTSSNIL PALESKKCYA NTRKFNYRFP NI 352

Nucleotide Sequence
(FASTA)

ATGGAAAAGT ATGAAAAGAT AGGCAAAATA GGTGAAGGCT CATATGGTGT GGTCTTTAAA 60

TGCAGAAACA GGGACACTGG ACAGATAGTG GCAATCAAGA AGTTCCTTGA GTCAGAAGAT 120

GATCCTGTGA TCAAGAAGAT TGCTTTGCGT GAAATTCGCA TGCTAAAGCA ATTAAAGCAT 180

CCCAATCTTG TAAATCTTCT TGAAGTATTC AGAAGGAAGA GGAAGTTGCA CCTAGTGTTT 240

GAGTACTGCG ACCACACAGT CCTCCATGAA CTGGACAAGT ACCCACGTGG GGTCCCTGAG 300

CATTTAGTGA AGAGCATCAC CTGGCAAACG TTACAAGCTG TTAATTTCTG CCATAAACAT 360

CATTGTATTC ACCGTGATGT CAAGCCAGAG AATATCCTCA TCACCAGGCA TTCTGTTATT 420

AAGCTGTGTG ACTTCGGATT TGCCAGGTTA CTGACTGGAC CTAGTGACTA TTATACAGAC 480

TATGTGGCCA CCAGATGGTA TCGTGCACCA GAACTGCTGG TTGGAGACAC ACAGTATGGT 540

CCCCCTGTGG ATGTGTGGGC TATTGGCTGC GTATTTGCGG AGCTTCTGTC AGGAATTCCA 600

CTGTGGCCTG GGAAGTCAGA TGTTGATCAG CTGTATTTAA TAAGAAAAAG TCAGGGTGAT 660

CTTATAGCCA GACACCAGCA AGTGTTCAGC ACAAACCAGT TTTTCAGTGG GGTTAGCATC 720

CCTGATCCAG AAAACATGGA ACCTCTGGAA TTGCGGTTCC CAAACATCTC ATCTCAAGCA 780

CTGGGACTCA TGAAGGGCTG TTTGCACATG GATCCTGCTA AAAGGCTGGC ATGCCAACAG 840

CTGCTCGACC ATCCTTATTT TGATAGCATT CGGGATGAAG GTGATGGGGT GACAGATTCT 900

GAAAGATTGA GTCGGAAACA GACAAGGCTG CACAGAAAGT ATATTCCCGG GCTCCAGCAC 960

CTTCCGCAGT TAACAAGCAG TAATATTTTA CCCGCTTTGG AGAGCAAGAA GTGTTATGCT 1020

AACACCAGAA AATTCAACTA CCGTTTCCCT AACATCTAA 1059

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         yek+gk+GeGsyGvv+kcrn+dtgqivaikkflesedd+++kkialrei++lkqlkh+nl

Q: 4     YEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNL  63

         9***********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnllevfrrk+kl+lvfey+d+tvl+el++yp+Gv+e+lvk+i++q+l+a++fchk+++i

Q: 64    VNLLEVFRRKRKLHLVFEYCDHTVLHELDKYPRGVPEHLVKSITWQTLQAVNFCHKHHCI  123

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrd+kpenili++++v+klcdfGfarll++p+d+ytdyvatrwyrapellvgdt+yG++v

Q: 124   HRDVKPENILITRHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRAPELLVGDTQYGPPV  183

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         dvwaiGc++aell+G pl+pgksdvdqly+irk  G+li+rhq++fs+n++f+Gv++p++

Q: 184   DVWAIGCVFAELLSGIPLWPGKSDVDQLYLIRKSQGDLIARHQQVFSTNQFFSGVSIPDP  243

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         e++e+le ++p++++ +l l+k+cl++dpa+rl+c++ll+h+yf

Q: 244   ENMEPLELRFPNISSQALGLMKGCLHMDPAKRLACQQLLDHPYF  287

         *******************************************9

Domain Sequence
(FASTA)

YEKIGKIGEG SYGVVFKCRN RDTGQIVAIK KFLESEDDPV IKKIALREIR MLKQLKHPNL 60

VNLLEVFRRK RKLHLVFEYC DHTVLHELDK YPRGVPEHLV KSITWQTLQA VNFCHKHHCI 120

HRDVKPENIL ITRHSVIKLC DFGFARLLTG PSDYYTDYVA TRWYRAPELL VGDTQYGPPV 180

DVWAIGCVFA ELLSGIPLWP GKSDVDQLYL IRKSQGDLIA RHQQVFSTNQ FFSGVSIPDP 240

ENMEPLELRF PNISSQALGL MKGCLHMDPA KRLACQQLLD HPYF 284

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

xtr:100496578

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013