EPS-XET-00033

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-XET-00033

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	176.9	6.9E-52	770	1016	247

Status

Unreviewed

Ensembl Protein

ENSXETP00000042967

UniProt Accession

F6PVN1;

Protein Name

Protein Synonyms/Alias

Gene Name

phlpp2

Gene Synonyms/Alias

phlpp2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000019856	ENSXETP00000051176	ENSXETT00000051176
ENSXETG00000019856	ENSXETP00000042967	ENSXETT00000042967

Organism

Xenopus tropicalis

Functional Description

Protein Length

1296

Protein Sequence
(FASTA)

MKRSGSRNCL NQKSCLGSRE REWLREDPNR GCVYVYGTDT SASSPDLLVV LCTVETSVSE 60

ICASEGRDGL YIQLNGDLVR RLDPQERPLH MIYKYLAALG FQDALRIQEE AAYSDLSCMI 120

RFYSELPTPV EQQDRILLSG EFMVRKGKTQ LHKWAERQVV LCGTSLIVSS VKDCHAGKMH 180

ILPLVGGKIE EIKRRPQCLA FYSAGAQAQT YHISFDFPGD YQRWYRQASI VVSQRPGTVD 240

LSCQSLEGVP DHLFYSQDIT SLNLRHNFMN PQCSGGVSTL CRFSQLKVLN LSHNNLREFP 300

LQICDITNLT ELNMSCNRLK QLPAELSHLQ SLQTLNLDGN SLTSLPEELG SLQQLSTLGL 360

AFNNLSSVPK VYEKLISLEK LCMAGNRLEA LSLQILNSMP HLKHIDLRMN LIKQIASGSL 420

EGINHITHLD VRDNHLTGLD LSCLGNLEQL HCERNQLKEL SLCGFSLKLV LASFNSLTYV 480

SVYPAPMQLT SLEMARNCLA SVPEWVCEAR KLEVLDLSWN LLTDLPLRVM SSLSLRKLLI 540

GHNHLQCLPS PVENIPLETL DVQHNLLKQL PGSLFTMAIN LRFLNASANS LEFLPSACVG 600

MDIVSQLQVL YITNNSLTDH CVPALTMHMN LRVLHMAYNQ LDTFPASKLN KLENLEELNL 660

SGNRLKSLPS TVSNCKRLHT LIAHSNCISV FPEIFNLPHI QLVDLSCNSL TEILVPENLP 720

PALRELDLQG NNDLVLSHRL LDFLSHIPTF KIDNKPVPKS DLSVPSVPWT HGLAEMSGQR 780

NKLCVSSLAI ADFAEGVEAL YGMFDGDKNE EVPRLLQCTV GDVLLEEIQR SSCDKAFMCL 840

TFLVSHGKLG MAGQKLGSSA LLCYIGQGVS DGNSSFTLTV ANVGTCQAVL CRNGQTISLS 900

RVFNLEHCPE ELRRIKEQKA IITEDNKVNG VTCCTRLLGC TYLYPWVIPD PHISTVTLTV 960

QDEYLILGNR ALWEHVPPKE AVEAIRHLPN PRAAAKKLCT LALSYGCQDN VAALVIYLNI 1020

GEDSCTCDMH GLALPSPSAL TSPTTTKESP ESVTPSSSSG IASEFSSEIS VSEVSSDVGS 1080

TASDEHTVAS LDSGLITRPE RRCSLHPVPS NSTFQRQPSC ATFSSNQSDN GLDSDDELQA 1140

ETINCNGSKV EVEVDIHCNK QHSSEALSFG SCWEVEEDCC GISVQILRQN SINQHNIACS 1200

SHDRDDMPPT SRSCMFIKKH SNGSVVPLEE ILDLIEVASE APKRKTGYFS APSQIEPEDK 1260

FVLSSDMEND ARVQLGNVDS AADNKANSQE EFDTAL 1296

Nucleotide Sequence
(FASTA)

ATGAAGCGCA GTGGAAGCAG AAACTGTTTG AACCAGAAGA GTTGCCTTGG CTCTCGTGAG 60

CGGGAATGGC TGCGAGAAGA TCCAAACAGA GGCTGCGTCT ATGTGTATGG AACAGACACC 120

AGTGCTTCCA GCCCTGATCT TCTTGTAGTC CTTTGCACAG TGGAAACCTC TGTATCAGAG 180

ATCTGTGCTA GTGAGGGGAG AGATGGCCTT TATATTCAGC TCAATGGAGA TCTTGTCAGG 240

AGGCTGGATC CTCAGGAGCG ACCGTTGCAC ATGATATATA AATACTTAGC TGCTCTGGGC 300

TTTCAAGATG CCCTGCGGAT CCAAGAGGAA GCAGCTTACT CAGACCTAAG CTGCATGATC 360

CGGTTCTATA GTGAGTTGCC AACTCCTGTG GAACAACAGG ATCGGATTTT ATTATCTGGA 420

GAGTTTATGG TGCGTAAAGG CAAAACTCAG CTACACAAGT GGGCAGAGAG ACAAGTTGTA 480

CTTTGTGGGA CAAGTTTAAT TGTATCTTCT GTGAAGGACT GTCATGCAGG AAAAATGCAC 540

ATTCTGCCCC TTGTTGGGGG CAAGATCGAG GAGATTAAAC GCAGACCTCA GTGTCTGGCT 600

TTCTATTCAG CTGGAGCCCA GGCTCAAACG TACCACATCA GCTTTGATTT CCCTGGAGAT 660

TATCAGCGAT GGTACCGCCA GGCATCTATT GTTGTGTCAC AAAGGCCCGG CACTGTTGAT 720

CTATCTTGTC AAAGCTTAGA GGGGGTTCCA GATCATCTGT TCTACAGCCA GGACATCACA 780

TCCTTAAATC TACGCCATAA CTTTATGAAT CCACAATGTT CAGGGGGCGT AAGCACCCTG 840

TGCAGGTTTT CACAGCTGAA AGTTCTCAAT TTATCGCATA ACAACCTGAG AGAGTTCCCC 900

CTTCAAATCT GTGACATTAC AAACCTGACA GAGCTGAACA TGTCCTGTAA CAGACTAAAA 960

CAGCTGCCAG CAGAACTTAG TCACCTGCAA AGTCTACAGA CTCTGAATCT GGATGGGAAT 1020

TCTTTGACCT CATTACCTGA GGAGCTTGGA TCTCTGCAGC AACTGTCTAC TCTGGGATTG 1080

GCATTCAATA ACCTAAGCAG TGTTCCAAAG GTCTATGAGA AACTGATTTC TCTGGAAAAG 1140

CTGTGTATGG CAGGAAACCG GTTGGAAGCC TTAAGTCTTC AGATCCTAAA TAGTATGCCT 1200

CATTTGAAGC ACATTGACCT GAGGATGAAT CTTATTAAAC AGATTGCAAG TGGTAGTCTA 1260

GAAGGAATAA ACCACATCAC TCACCTTGAT GTACGTGATA ATCATCTAAC AGGACTGGAT 1320

CTCAGCTGCT TGGGGAATCT GGAGCAATTG CATTGTGAGC GAAATCAGCT GAAGGAGCTT 1380

TCACTCTGTG GCTTCTCCCT GAAATTGGTT CTTGCCAGCT TTAATAGTTT AACATATGTG 1440

AGTGTGTATC CTGCCCCTAT GCAGCTCACT TCTTTGGAAA TGGCCAGGAA TTGCTTGGCT 1500

TCAGTTCCTG AGTGGGTGTG TGAAGCTAGG AAGTTGGAGG TTTTGGATCT AAGCTGGAAC 1560

TTGCTGACTG ATCTTCCTTT AAGAGTGATG AGTAGTTTGA GTCTGCGGAA ATTGCTTATT 1620

GGGCATAACC ATCTCCAGTG CTTGCCAAGT CCTGTGGAGA ATATCCCACT GGAAACTCTG 1680

GATGTGCAAC ATAATTTACT AAAGCAGCTT CCTGGTTCAC TTTTCACAAT GGCTATAAAT 1740

CTCAGGTTTC TTAATGCATC TGCAAATTCA TTGGAGTTCT TACCATCAGC ATGTGTTGGG 1800

ATGGACATTG TGAGCCAACT TCAAGTTCTC TACATAACCA ACAATAGTCT TACAGACCAT 1860

TGTGTTCCTG CATTAACTAT GCACATGAAC CTCAGGGTCC TGCATATGGC CTACAATCAG 1920

CTGGATACCT TCCCAGCCAG CAAACTCAAT AAACTGGAGA ATTTGGAAGA ACTGAACCTC 1980

AGTGGAAATC GTCTCAAGTC ACTCCCAAGC ACTGTGTCCA ACTGCAAGCG TCTCCACACT 2040

CTGATCGCTC ACTCCAACTG CATCAGCGTA TTCCCTGAAA TCTTTAATCT TCCACATATC 2100

CAGTTGGTTG ACTTGAGCTG TAACAGTCTG ACGGAAATCC TGGTTCCTGA AAATCTCCCA 2160

CCTGCCCTGC GTGAGCTGGA CCTGCAAGGG AACAATGACC TGGTCTTGAG TCATCGGCTC 2220

CTTGACTTCC TCAGCCATAT TCCCACATTC AAAATTGACA ACAAGCCTGT GCCAAAGTCA 2280

GACCTGAGTG TGCCATCTGT ACCCTGGACT CATGGTTTGG CAGAGATGTC TGGACAGAGG 2340

AACAAGCTGT GCGTGTCTTC CCTGGCAATA GCTGACTTTG CAGAAGGGGT TGAGGCACTG 2400

TATGGCATGT TTGATGGAGA CAAAAATGAA GAGGTGCCAC GTTTACTGCA GTGCACCGTG 2460

GGTGATGTTC TTCTTGAAGA GATCCAACGG TCAAGCTGTG ACAAAGCCTT TATGTGCCTC 2520

ACATTCCTGG TGTCACATGG GAAGCTGGGA ATGGCTGGTC AGAAGCTTGG CTCTTCAGCA 2580

CTCTTGTGTT ACATTGGCCA AGGGGTGTCA GATGGTAACA GCAGCTTCAC TCTGACTGTA 2640

GCCAATGTGG GGACATGCCA AGCTGTCTTG TGTCGGAATG GGCAAACAAT TTCCCTGTCC 2700

AGAGTATTCA ACTTAGAACA CTGCCCTGAG GAACTGAGAA GGATTAAAGA GCAAAAAGCA 2760

ATTATTACAG AGGATAACAA GGTAAATGGA GTAACTTGCT GCACACGTTT GCTAGGCTGC 2820

ACATATCTAT ATCCTTGGGT GATTCCTGAT CCACATATCT CGACAGTAAC TCTTACTGTA 2880

CAGGATGAAT ATTTGATTCT GGGAAATCGA GCTCTGTGGG AGCATGTTCC TCCCAAGGAA 2940

GCTGTGGAAG CCATACGTCA CTTGCCTAAC CCAAGAGCAG CTGCAAAGAA GCTCTGCACT 3000

TTAGCACTAA GCTATGGCTG TCAGGATAAT GTTGCTGCCC TGGTGATCTA TCTTAACATT 3060

GGAGAGGATT CTTGCACTTG TGACATGCAT GGTCTGGCCT TGCCTAGCCC ATCTGCTTTA 3120

ACTTCCCCAA CTACAACAAA AGAATCTCCT GAATCGGTGA CACCATCTTC CAGCAGTGGA 3180

ATTGCATCTG AATTCAGCAG TGAGATATCT GTTTCAGAGG TAAGCAGCGA TGTGGGCTCC 3240

ACTGCATCTG ATGAGCACAC AGTAGCAAGT CTGGACAGTG GACTCATCAC AAGACCTGAA 3300

CGAAGATGCA GTCTCCACCC GGTTCCATCC AACAGCACTT TCCAGCGACA GCCATCTTGT 3360

GCCACATTTT CAAGCAATCA GTCAGATAAT GGTTTGGACA GTGATGACGA GCTGCAAGCA 3420

GAAACAATCA ACTGCAATGG TAGCAAAGTA GAGGTAGAAG TAGATATTCA CTGTAATAAG 3480

CAGCATAGTT CTGAAGCTCT GTCCTTTGGC TCATGTTGGG AAGTAGAGGA AGACTGCTGT 3540

GGGATATCTG TACAAATACT TAGACAGAAC AGTATTAACC AACACAACAT AGCATGTTCA 3600

AGTCACGATA GAGATGATAT GCCTCCTACT TCGAGATCAT GTATGTTCAT CAAGAAACAC 3660

TCAAATGGTT CTGTGGTGCC ACTGGAAGAG ATTCTGGACT TGATTGAGGT CGCCTCTGAA 3720

GCTCCTAAAA GAAAAACTGG CTACTTTTCT GCTCCTTCTC AAATAGAGCC TGAGGATAAG 3780

TTTGTGCTTT CTTCTGATAT GGAGAATGAC GCGAGGGTGC AGCTTGGTAA TGTAGACAGT 3840

GCTGCAGATA ATAAAGCAAA CTCACAGGAA GAGTTTGATA CAGCTTTGTG A 3891

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

          +g+++++g+rn+++ ++ +  +f++  e+     ++g++DG++++ev + +++++ ++l

Q: 770   THGLAEMSGQRNKLCVSSLAIADFAEGVEA-----LYGMFDGDKNEEVPRLLQCTVGDVL  824

         6899*********************99875.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++   k+++  +Fl  + +l       ++ +k Gs+a++++i +

Q: 825   LEEIQ----RSSCDKAFMCLTFLVSHGKL------GMAGQKLGSSALLCYIGQGvsdgns  874

         ***99....88888899************......89**************977788889

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsr.edEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcrng+ ++ls+ ++ ++ ++El+Ri+e+++ +++++  +v+Gv+

Q: 875   sfTLTVANVGTCQAVLCRNGQTISLSRVFNLEHcPEELRRIKEQKAIITEDN--KVNGVT  932

         99****************************98637**********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R lG++yl+p+v+p+P+++ ++lt +de+liL+   lw++v+++eav+++r+  +

Q: 933   CCTRLLGCTYLYPWVIPDPHISTVTLTVQDEYLILGNRALWEHVPPKEAVEAIRHLPN--  990

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           +++aakkL++lal++g++dnv+a+v+

Q: 991   --PRAAAKKLCTLALSYGCQDNVAALVI  1016

         ..*********************99997

Domain Sequence
(FASTA)

THGLAEMSGQ RNKLCVSSLA IADFAEGVEA LYGMFDGDKN EEVPRLLQCT VGDVLLEEIQ 60

RSSCDKAFMC LTFLVSHGKL GMAGQKLGSS ALLCYIGQGV SDGNSSFTLT VANVGTCQAV 120

LCRNGQTISL SRVFNLEHCP EELRRIKEQK AIITEDNKVN GVTCCTRLLG CTYLYPWVIP 180

DPHISTVTLT VQDEYLILGN RALWEHVPPK EAVEAIRHLP NPRAAAKKLC TLALSYGCQD 240

NVAALVI 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Saccharomyces cerevisiae"; ?>