EKS-XET-00057

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00057

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	378.5	2.0E-113	151	433	283

Status

Unreviewed

Ensembl Protein

ENSXETP00000044938

UniProt Accession

F7DAA0;

Protein Name

Protein Synonyms/Alias

Gene Name

cdk16

Gene Synonyms/Alias

cdk16;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000020815	ENSXETP00000044938	ENSXETT00000044938

Organism

Xenopus tropicalis

Functional Description

Protein Length

482

Protein Sequence
(FASTA)

SEPIVRNGRS LSSHSMQSFL HHYTASSFQK PPIPRPHSAV CRSLSSYLNR TSRLEIVHED 60

LKMGSDGESD QASGSSDEVQ SPVRVRMRNN AARKISTEDI NKRLSLPADI RLPEGYLEKL 120

ALSSPPFDKP LSRRLRRVSL SEIGFGKLET YIKLDKLGEG TYATVYKGRS KLTENLVALK 180

EIRLEHEEGA PCTAIREVSL LKDLKHANIV TLHDIIHTER TLTLVFEYLD KDLKQYLDDC 240

GNLINLHNVK LFLYQLLRGL SYCHRRKVLH RDLKPQNLLI NEKGELKLAD FGLARAKSIP 300

TKTYSNEVVT LWYRPPDILL GSTEYSTQID MWGVGCIFYE MVTGRPLFPG STVEEQLHFI 360

FRILGTPTEE TWPGILSNEE FKSYNYPRYY PDPIQKHAAR LDSDGANLLT KLLQQLEGRN 420

RISAEEAMRH LYFQELGERI HKLPDTTSIF ALKEISLEPE IKHRPVPEPV HVQSRRLSLV 480

LG 482

Nucleotide Sequence
(FASTA)

TCAGAGCCCA TCGTCAGAAA TGGGAGAAGC CTCTCGTCCC ACAGCATGCA ATCCTTCCTG 60

CACCACTACA CCGCCAGCTC CTTTCAAAAG CCGCCCATCC CCCGGCCTCA CAGCGCCGTG 120

TGCCGCAGCC TGAGCTCTTA CCTGAATCGG ACCAGCAGAC TAGAGATCGT CCACGAAGAC 180

TTGAAGATGG GGTCGGATGG AGAGAGCGAC CAAGCGTCCG GCTCCTCGGA TGAGGTTCAG 240

TCGCCGGTGC GAGTGCGAAT GCGGAACAAC GCCGCGCGGA AGATATCAAC GGAGGACATC 300

AACAAGCGCC TGTCCCTCCC CGCCGATATC CGCCTCCCCG AGGGGTACCT GGAGAAGCTG 360

GCGCTTAGTA GCCCCCCCTT CGACAAACCC CTGAGCCGGC GGCTGCGGCG AGTCTCCCTG 420

TCGGAAATCG GCTTTGGGAA GCTGGAGACC TACATCAAGC TGGACAAACT GGGAGAGGGC 480

ACCTACGCCA CGGTGTACAA GGGGCGCAGC AAACTCACCG AGAACCTGGT GGCCCTGAAG 540

GAGATTCGGC TGGAACATGA GGAGGGGGCA CCATGCACAG CTATTCGGGA AGTTTCTCTT 600

CTGAAGGACC TGAAACACGC CAACATCGTC ACCCTGCACG ATATCATACA CACCGAGAGG 660

ACTTTGACGC TGGTCTTCGA GTATTTGGAT AAAGATCTCA AGCAGTATTT GGACGACTGT 720

GGAAACCTCA TCAACCTCCA TAATGTAAAG CTCTTCCTCT ACCAGCTCCT TCGGGGACTG 780

TCTTATTGCC ACCGGCGTAA AGTTCTGCAC AGGGACCTAA AGCCTCAGAA CCTGTTGATC 840

AATGAGAAAG GGGAGCTCAA GCTGGCGGAT TTTGGACTGG CTCGGGCAAA GTCCATTCCC 900

ACCAAGACTT ACTCTAATGA AGTGGTGACC CTGTGGTACC GACCCCCGGA CATACTACTT 960

GGATCCACGG AATACTCCAC CCAGATTGAT ATGTGGGGCG TAGGCTGCAT CTTCTATGAG 1020

ATGGTCACAG GCCGACCCCT CTTCCCTGGA TCCACCGTGG AGGAACAACT ACATTTTATA 1080

TTCAGAATTC TAGGAACCCC TACTGAAGAA ACCTGGCCTG GCATTCTGTC CAATGAAGAA 1140

TTCAAGTCGT ATAATTACCC TCGGTATTAC CCGGATCCCA TCCAGAAACA CGCTGCAAGG 1200

CTGGACTCCG ATGGAGCCAA TCTCCTGACC AAACTACTGC AGCAGCTGGA AGGGAGGAAC 1260

CGGATTTCAG CAGAGGAAGC AATGAGGCAC TTGTACTTCC AGGAACTGGG GGAGAGGATC 1320

CACAAACTAC CAGACACCAC GTCCATCTTT GCACTAAAGG AGATCAGCCT GGAGCCAGAG 1380

ATAAAGCACA GGCCGGTGCC CGAGCCAGTT CACGTGCAGT CGCGTCGGCT CAGCCTGGTC 1440

CTCGGGTGA 1449

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl+k+geGty++vyk+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 151   YIKLDKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  209

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++++ ++++l+Lvfe+l++dLk++l+++ +  ++l++vk +l+qll+gl+y+H++k

Q: 210   VTLHDIIH-TERTLTLVFEYLDKDLKQYLDDCGN-LINLHNVKLFLYQLLRGLSYCHRRK  267

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s p+kty++evvTlwYr+P++Llg++eYst

Q: 268   VLHRDLKPQNLLINEKGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTEYST  327

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e++t +plf+g++  +ql+ if++lgtp+e++wp++ + +e+k +++p

Q: 328   QIDMWGVGCIFYEMVTGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKsYNYP  387

         *******************************************************88999

S: 240   kkkkkklkekvkklkekaldlleklla.ldpkkRisakealqhkyf  284

         ++ +  ++++  +l++++ +ll+kll+ l+ ++Risa+ea++h yf

Q: 388   RYYPDPIQKHAARLDSDGANLLTKLLQqLEGRNRISAEEAMRHLYF  433

         99999********************963799**************8

Domain Sequence
(FASTA)

YIKLDKLGEG TYATVYKGRS KLTENLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIIHTER TLTLVFEYLD KDLKQYLDDC GNLINLHNVK LFLYQLLRGL SYCHRRKVLH 120

RDLKPQNLLI NEKGELKLAD FGLARAKSIP TKTYSNEVVT LWYRPPDILL GSTEYSTQID 180

MWGVGCIFYE MVTGRPLFPG STVEEQLHFI FRILGTPTEE TWPGILSNEE FKSYNYPRYY 240

PDPIQKHAAR LDSDGANLLT KLLQQLEGRN RISAEEAMRH LYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Erinaceus europaeus"; ?>Homo sapiens"; ?>Nomascus leucogenys"; ?>Petromyzon marinus"; ?>Procavia capensis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013