EKS-XET-00303

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00303

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	386.1	9.1E-116	54	315	262

Status

Unreviewed

Ensembl Protein

ENSXETP00000020839

UniProt Accession

F7EJU0;

Protein Name

Protein Synonyms/Alias

Gene Name

map2k6

Gene Synonyms/Alias

map2k6;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000022954	ENSXETP00000049651	ENSXETT00000049651
ENSXETG00000022954	ENSXETP00000020839	ENSXETT00000020839

Organism

Xenopus tropicalis

Functional Description

Protein Length

335

Protein Sequence
(FASTA)

LAQILGKKKN PGLKIPKEAF DQPQVSSPTP PRDLDSKACI LIGEKNFEVK ADDLEPIEEL 60

GRGAYGVVEK MRHVPSEQIM AVKRIRATVN SQEQKRLLMD LDISMRTVDC HFTVTFYGAL 120

FREGDVWICM ELMDTSLDKF YKNVIDKGLT IPEDILGKIA VSIVRALEHL HSKLSVIHRD 180

VKPSNVLINK EGQVKMCDFG ISGYLVDSVA KTMDAGCKPY MAPERINPEL NQKGYSVKSD 240

IWSLGITLIE LAILRFPYDS WGTPFQQLKQ VVEEPSPQLP ADKFSAEFVD FTSKCLKKNS 300

KERPTYPELM QHHFFVLHES KNTDVASFVK RILGD 335

Nucleotide Sequence
(FASTA)

TTAGCACAAA TTTTAGGCAA GAAGAAAAAT CCTGGGCTGA AAATTCCAAA GGAGGCATTT 60

GACCAGCCAC AAGTCAGCTC TCCGACGCCA CCACGGGACT TGGACTCCAA AGCCTGCATC 120

CTCATAGGAG AAAAGAACTT TGAAGTCAAG GCCGATGACT TGGAACCAAT AGAAGAGCTA 180

GGCCGGGGAG CCTATGGTGT CGTGGAAAAG ATGCGCCATG TTCCCAGTGA GCAGATAATG 240

GCAGTGAAGC GCATCAGAGC AACTGTGAAC AGCCAGGAAC AGAAAAGGCT GCTGATGGAC 300

CTGGATATCT CTATGCGCAC AGTGGACTGC CATTTTACTG TCACGTTTTA TGGGGCCTTA 360

TTTAGAGAGG GGGATGTCTG GATCTGCATG GAGTTGATGG ATACGTCACT GGATAAATTT 420

TACAAGAATG TGATTGACAA AGGCCTGACC ATCCCCGAGG ACATACTAGG AAAAATAGCA 480

GTTTCGATTG TTAGAGCATT AGAACATCTG CATAGTAAAC TCTCAGTGAT CCACAGAGAT 540

GTGAAACCCT CCAACGTACT GATAAACAAA GAAGGCCAGG TGAAGATGTG TGACTTTGGA 600

ATCAGCGGTT ATCTTGTTGA CTCTGTAGCC AAAACCATGG ATGCTGGCTG CAAACCCTAC 660

ATGGCTCCTG AAAGAATAAA CCCAGAGCTG AACCAGAAAG GGTATAGTGT AAAATCGGAC 720

ATTTGGAGCC TTGGAATAAC ATTGATTGAA CTGGCCATTC TGCGGTTTCC ATATGACTCC 780

TGGGGGACCC CTTTCCAACA GCTAAAACAA GTGGTCGAAG AGCCCTCCCC ACAGCTGCCT 840

GCAGACAAGT TTTCTGCTGA GTTTGTTGAC TTTACCTCAA AGTGCTTGAA GAAAAATTCC 900

AAAGAGCGTC CAACTTATCC AGAGCTTATG CAACACCATT TCTTTGTGCT GCATGAATCC 960

AAGAACACTG ATGTGGCATC TTTCGTTAAA CGCATCTTGG GAGATTAA 1008

Domain Profile

S: 1     lekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyi  60

         le +eelG+G++gvVek++h +s++i+avK+ir++++++eqk++l++l++ +++ +++++

Q: 54    LEPIEELGRGAYGVVEKMRHVPSEQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCHFT  113

         67899*******************************************************

S: 61    vkfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylke  120

         v+fyGa+++egdv+icmelmd tsldk++k+v++k  +ipe++lgkiav++v+ale+l++

Q: 114   VTFYGALFREGDVWICMELMD-TSLDKFYKNVIDKGLTIPEDILGKIAVSIVRALEHLHS  172

         *********************.**************************************

S: 121   klkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksa.vGtksYmaPErieg...k  176

         kl++iHRDvKPsN+L+n++G+vK+CDFG+sg+lvds+Ak++ +G+k+YmaPEri++   +

Q: 173   KLSVIHRDVKPSNVLINKEGQVKMCDFGISGYLVDSVAKTMdAGCKPYMAPERINPelnQ  232

         ********************************************************9999

S: 177   kkYsvksdvWslGltlvelatgrypyeklkeilellkaivneeppklpeeefseefqefv  236

         k Ysvksd+WslG+tl+ela+ r+py+++ +++++lk++v+e++p+lp+++fs ef++f

Q: 233   KGYSVKSDIWSLGITLIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFT  292

         9***********************************************************

S: 237   skClkkdekeRpklkellkhafi  259

         skClkk++keRp++ el++h+f+

Q: 293   SKCLKKNSKERPTYPELMQHHFF  315

         ********************996

Domain Sequence
(FASTA)

LEPIEELGRG AYGVVEKMRH VPSEQIMAVK RIRATVNSQE QKRLLMDLDI SMRTVDCHFT 60

VTFYGALFRE GDVWICMELM DTSLDKFYKN VIDKGLTIPE DILGKIAVSI VRALEHLHSK 120

LSVIHRDVKP SNVLINKEGQ VKMCDFGISG YLVDSVAKTM DAGCKPYMAP ERINPELNQK 180

GYSVKSDIWS LGITLIELAI LRFPYDSWGT PFQQLKQVVE EPSPQLPADK FSAEFVDFTS 240

KCLKKNSKER PTYPELMQHH FF 262

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013