EKS-XET-00632

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00632

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK1	447.3	1.8E-134	21	277	257

Status

Unreviewed

Ensembl Protein

ENSXETP00000051081

UniProt Accession

Q5BL60;

Protein Name

Protein Synonyms/Alias

Calcium/calmodulin-dependent protein kinase I;

Gene Name

camk1

Gene Synonyms/Alias

camk1; camk1g; TGas061c18.1-001;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000023672	ENSXETP00000051081	ENSXETT00000051081

Organism

Xenopus tropicalis

Functional Description

Protein Length

383

Protein Sequence
(FASTA)

MPLDEDGPSW KKRAEDIRDI YEFREVLGTG AFSEVVLAEE KKTQKLVAIK CIPKKALEGK 60

ETSIENEIAV LRKIKHANIV SLEDIYESRS HLYLIMQLVS GGELFDRIVE KGFYTEKDAS 120

QLIKQILDAV KYLHDMGIVH RDLKPENLLY YSIDEDSKIM ISDFGLSKIE GSGSVMSTAC 180

GTPGYVAPEV LAQKPYSKAV DCWSIGVIAY ILLCGYPPFY DENDAKLFEQ ILKAEYEFDS 240

PYWDDISDSA KDFIQHLMEK DPNKRNTCDQ ALQHPWIAGD TALDKNIHES VSEQIRKNFA 300

KSRWKQAFNA TAVVRHMRKL QLGTSQEGPG QTTPTSPCHG NLLMPGDNHG SHSESCQDCC 360

SPKSSENNSL AYSTQHCAQS NRV 383

Nucleotide Sequence
(FASTA)

ATGCCCCTGG ATGAAGATGG GCCGAGTTGG AAGAAAAGAG CAGAAGACAT TAGAGATATC 60

TATGAATTTC GGGAAGTCTT AGGAACGGGT GCTTTCTCTG AAGTGGTCCT GGCAGAGGAG 120

AAGAAGACGC AGAAGTTGGT AGCCATTAAG TGTATTCCAA AGAAAGCCCT GGAGGGGAAA 180

GAGACCAGCA TAGAGAACGA GATTGCTGTG CTGAGAAAGA TCAAGCACGC TAATATTGTG 240

TCACTGGAGG ACATCTATGA GAGCCGGAGT CACCTATACC TTATCATGCA GCTGGTGTCG 300

GGGGGTGAGC TGTTTGACAG GATCGTGGAG AAAGGTTTCT ATACAGAGAA GGATGCCAGC 360

CAGCTCATCA AGCAGATTTT GGATGCTGTC AAGTACCTGC ACGATATGGG CATTGTGCAC 420

AGGGATCTAA AGCCGGAGAA TCTGCTCTAT TACAGTATAG ACGAAGATTC CAAAATTATG 480

ATCAGTGACT TTGGCCTCTC AAAAATCGAA GGGTCTGGAA GTGTAATGTC AACTGCCTGC 540

GGCACCCCAG GTTATGTTGC TCCGGAGGTG TTGGCTCAGA AGCCTTACAG TAAAGCAGTG 600

GATTGCTGGT CGATTGGTGT CATTGCATAC ATACTATTGT GCGGGTACCC ACCATTCTAC 660

GATGAAAATG ACGCCAAACT CTTTGAGCAG ATTCTGAAAG CCGAGTATGA GTTTGACTCG 720

CCGTACTGGG ACGACATCTC CGATTCAGCC AAAGATTTCA TCCAGCATCT AATGGAAAAG 780

GATCCAAATA AGCGCAACAC ATGTGACCAA GCCCTGCAAC ATCCATGGAT TGCTGGGGAC 840

ACTGCACTGG ATAAGAATAT CCATGAATCA GTCAGCGAGC AAATCAGGAA AAATTTTGCC 900

AAAAGCAGAT GGAAGCAAGC ATTCAATGCC ACTGCTGTGG TACGCCACAT GAGAAAGTTA 960

CAGCTGGGCA CAAGCCAAGA AGGACCCGGT CAGACCACAC CCACTAGCCC ATGCCATGGC 1020

AATCTTCTTA TGCCAGGGGA TAACCATGGC TCTCATTCGG AGAGTTGTCA AGACTGCTGT 1080

TCTCCAAAAT CCTCTGAAAA CAACTCGTTG GCCTATAGCA CCCAACACTG CGCACAATCC 1140

AACAGAGTTT AG 1152

Domain Profile

S: 1     yklkeklGeGafsevlkakekktqkavaikvikkkalkgkeesveneiavlkklkhpniv  60

         y+++e lG+Gafsev++a+ekktqk vaik+i kkal+gke+s+eneiavl+k+kh niv

Q: 21    YEFREVLGTGAFSEVVLAEEKKTQKLVAIKCIPKKALEGKETSIENEIAVLRKIKHANIV  80

         89**********************************************************

S: 61    alkdiyesksklylvlelvtGGelfdrivekgvytekdasevikqvleavkylhelgivh  120

         +l+diyes+s+lyl+++lv+GGelfdrivekg+ytekdas++ikq+l+avkylh++givh

Q: 81    SLEDIYESRSHLYLIMQLVSGGELFDRIVEKGFYTEKDASQLIKQILDAVKYLHDMGIVH  140

         ************************************************************

S: 121   rdlkPenllylskeedskikiadfGlskleeke.llktacGtvgyvapevlkqkkyskkv  179

         rdlkPenlly+s +edski+i+dfGlsk+e ++ +++tacGt+gyvapevl+qk+ysk+v

Q: 141   RDLKPENLLYYSIDEDSKIMISDFGLSKIEGSGsVMSTACGTPGYVAPEVLAQKPYSKAV  200

         ********************************99**************************

S: 180   dvWsiGvityillcGyppfydekeekllekilkgeyefesPyWdeisesakdfikkllel  239

         d+WsiGvi+yillcGyppfyde+++kl+e+ilk+eyef+sPyWd+is+sakdfi++l+e+

Q: 201   DCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIQHLMEK  260

         ************************************************************

S: 240   dpekrytieqaledpWi  256

         dp+kr t++qal++pWi

Q: 261   DPNKRNTCDQALQHPWI  277

         ****************8

Domain Sequence
(FASTA)

YEFREVLGTG AFSEVVLAEE KKTQKLVAIK CIPKKALEGK ETSIENEIAV LRKIKHANIV 60

SLEDIYESRS HLYLIMQLVS GGELFDRIVE KGFYTEKDAS QLIKQILDAV KYLHDMGIVH 120

RDLKPENLLY YSIDEDSKIM ISDFGLSKIE GSGSVMSTAC GTPGYVAPEV LAQKPYSKAV 180

DCWSIGVIAY ILLCGYPPFY DENDAKLFEQ ILKAEYEFDS PYWDDISDSA KDFIQHLMEK 240

DPNKRNTCDQ ALQHPWI 257

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

xtr:549023

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013