EPS-XET-00030

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-XET-00030

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	191.5	2.4E-56	663	908	246

Status

Unreviewed

Ensembl Protein

ENSXETP00000064091

UniProt Accession

F7A1H1;

Protein Name

Protein Synonyms/Alias

Gene Name

phlpp1

Gene Synonyms/Alias

phlpp1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000031560	ENSXETP00000064091	ENSXETT00000065429

Organism

Xenopus tropicalis

Functional Description

Protein Length

1166

Protein Sequence
(FASTA)

LFCNIYFVGK SNCGGFSERT QLSGTYNVRK GKMQLPVNRW ARRQVILCGT CLIVSSVKES 60

QTGKMHILPL IGGKVEEVKK HQHCLAFSSS GPQSQTYYIC FDTFTDYLRW LRQASKIASQ 120

RTSSVDLSCC SLEYLPENLF YSQDITHLNL KQNILRLSPG PAAEGTLDDL QRFTKLRSLN 180

LSNNNLGSFP LAVCSIPTLT ELNLSCNALR AIPSQVGDMN NLQTFLLDGN YLQSLPAEMG 240

NMHQLNYLGL SFNEFTDIPE VVEKMASMDR LCMPGNALDI LELQTLRKMS QIKHVDLRLN 300

EIRGLVIDEP DFLPHITQLD LRDNKLTDLD VTALSNLEVL HCERNRLRCL KISGFFLKAL 360

YASSNELLNL DVYPNPCYLS YMDISRNCLH SLPEWFSECR NLEVLDVSHN HLNELPDRLF 420

CTSALRKLLL GYNQLQRLPE LIENNQLEVL DVQHNQLLEL PANLLLKLNS LRCLNASANH 480

LETLPATCLS EESHSMLQEL YLTNNNLTDK CVPLLMGHPH LKILHMAFNH LQTFPASKMA 540

KLEELEEIDI SGNKLKAMPT TIMNCRRMHT VIAHSNCLEV FPEVMQLSEI KCVDLSCNEL 600

TEITLPENLP PRLQELDLTG NARLLLDHKT LELLNSNIRF FKVDQPSCGF SGSEASGVPA 660

VWSHGYAEAS GVKSKLCVAS LLVNNFCDNR EAVYGVFDGE RNVEVPSLLQ CTMSDILADE 720

LQKTKSEEEY MGNTFLVMQR KLGTAGQKLG GSAVLCHIKH DPMDPAGCFT LTTANVGKCQ 780

TVICRDGKPL NLSKHLTVSC EEELKRIKQH KAIITEDGKV NGVTDSTRIL GYTFLHPSVT 840

PRPHVQSVTL TPQDEFFILG SKGLWDSLSM EEAVETVRNV PDALAASKKL CSLAQSYGCS 900

GSLCAVVVQL NVTEDCICCC ELNGGMPPPS PGIFTPSVNV VIKDRAPDSL GMPSSSSGLA 960

SEISSEISTS EMSSEVGSTA SDEPPAVSLH ENGVGPVGCP TEQRCTLHPV CLSSSFQRQL 1020

SSATFSSAFS DNGLDSEDEE PIEGVFSNGS RVEVEVDIHC SRTKSGCQTV PAVLTESTDE 1080

GIVINGNEDD MGGPGKRQDF SSNTLGRQRR GNGSVAPLEK SHNLIEIAAD APLRKQGGYF 1140

AAPAQPDPDD QFIIPPELEE EVKEIM 1166

Nucleotide Sequence
(FASTA)

TTATTTTGTA ACATTTATTT TGTAGGAAAG TCAAACTGTG GTGGTTTCTC TGAACGGACT 60

CAACTTTCGG GAACGTATAA TGTTCGTAAA GGGAAGATGC AGCTGCCTGT AAACAGATGG 120

GCACGACGGC AAGTGATTCT TTGTGGAACT TGTCTAATTG TATCATCGGT GAAGGAAAGC 180

CAGACTGGAA AGATGCATAT TCTACCTTTA ATAGGTGGAA AAGTGGAAGA AGTAAAGAAG 240

CACCAGCACT GCCTGGCATT CAGCTCATCT GGTCCACAGA GTCAAACATA CTATATTTGC 300

TTTGACACAT TCACAGATTA CTTGAGATGG CTCCGACAGG CTTCTAAGAT TGCATCTCAG 360

CGCACCAGTT CTGTGGATCT GTCCTGCTGC AGCTTGGAAT ATCTCCCAGA GAACCTGTTC 420

TACAGCCAAG ATATCACACA CCTCAACCTG AAACAAAATA TTCTCAGACT CTCTCCAGGT 480

CCAGCAGCAG AAGGCACTCT TGATGATCTT CAGAGGTTTA CAAAGTTGAG GAGTCTCAAT 540

CTTTCCAATA ATAATTTGGG TAGTTTCCCA CTGGCTGTTT GCAGTATCCC TACTCTGACA 600

GAACTCAACC TTTCCTGTAA TGCTCTTCGG GCCATTCCTT CACAGGTTGG AGACATGAAC 660

AATTTGCAGA CGTTCCTTTT GGATGGCAAC TACCTTCAGT CTCTCCCTGC TGAAATGGGA 720

AACATGCACC AGCTAAACTA TTTGGGCCTC TCATTTAATG AATTTACAGA CATTCCTGAG 780

GTGGTGGAAA AGATGGCTTC CATGGATAGA TTGTGTATGC CAGGGAACGC TTTGGATATC 840

CTAGAGTTGC AGACTCTGAG GAAGATGTCA CAGATTAAGC ATGTAGATTT AAGGCTAAAT 900

GAAATCAGAG GATTGGTAAT AGATGAGCCA GATTTTTTGC CTCACATCAC CCAGTTGGAC 960

CTCCGAGATA ACAAGTTGAC TGATCTTGAT GTGACTGCCC TCAGCAACTT AGAAGTCCTG 1020

CACTGTGAGA GGAACAGACT AAGGTGTCTT AAAATCAGTG GCTTCTTCTT AAAAGCACTT 1080

TATGCATCTT CTAATGAACT CCTAAATCTT GATGTGTATC CAAACCCTTG TTATTTATCA 1140

TACATGGACA TTTCTAGAAA CTGTCTGCAT TCCCTTCCTG AGTGGTTCAG TGAATGCAGA 1200

AATTTAGAGG TACTGGATGT GAGCCACAAT CACCTAAATG AGCTTCCTGA CCGGTTATTC 1260

TGTACCAGTG CTTTGAGAAA GCTACTTTTA GGTTACAACC AGCTGCAAAG GCTTCCAGAA 1320

TTAATTGAGA ACAACCAACT TGAGGTACTT GATGTGCAGC ACAACCAGCT ATTGGAGCTC 1380

CCTGCCAACT TGCTGCTTAA ATTAAACAGC CTAAGGTGCC TCAATGCCTC TGCCAACCAT 1440

TTAGAAACCC TTCCTGCCAC ATGTCTGTCC GAAGAGTCGC ACAGTATGTT GCAGGAGCTG 1500

TATCTGACTA ATAATAATCT CACTGACAAA TGTGTGCCCT TATTAATGGG ACATCCCCAC 1560

CTGAAGATCC TGCACATGGC CTTCAATCAT CTACAGACTT TCCCAGCAAG TAAAATGGCC 1620

AAACTGGAGG AACTAGAAGA AATAGATATT AGCGGGAACA AGCTGAAAGC CATGCCAACT 1680

ACCATAATGA ACTGCAGGCG CATGCACACA GTCATTGCTC ACTCCAACTG CCTGGAAGTC 1740

TTCCCTGAAG TTATGCAGCT ATCCGAGATT AAGTGTGTGG ACTTAAGCTG CAATGAACTT 1800

ACTGAAATCA CGTTGCCTGA AAACCTACCT CCCAGACTGC AGGAACTGGA CCTGACTGGT 1860

AATGCCCGCT TGCTCCTTGA CCACAAAACC CTGGAGCTTC TGAACAGCAA CATTCGGTTC 1920

TTTAAGGTGG ACCAGCCATC CTGTGGGTTC TCTGGAAGTG AAGCATCAGG AGTGCCAGCT 1980

GTGTGGAGCC ATGGATATGC AGAGGCATCA GGTGTTAAGA GCAAGCTTTG TGTAGCATCC 2040

CTTTTGGTCA ACAATTTCTG TGATAACCGT GAAGCTGTGT ATGGTGTGTT TGATGGTGAG 2100

CGGAATGTCG AGGTACCCAG CCTGCTGCAG TGCACAATGA GTGACATACT AGCTGATGAA 2160

CTGCAAAAAA CAAAGAGCGA GGAGGAGTAC ATGGGAAATA CCTTCCTGGT TATGCAGAGG 2220

AAACTGGGTA CAGCTGGACA AAAACTAGGG GGCTCTGCTG TCCTCTGCCA CATAAAGCAT 2280

GATCCCATGG ACCCTGCTGG ATGTTTCACG CTCACCACAG CCAATGTAGG CAAGTGCCAA 2340

ACTGTTATCT GCAGAGATGG GAAGCCGCTT AACCTGTCCA AACACCTTAC AGTCAGCTGT 2400

GAAGAAGAAT TAAAGAGAAT AAAACAACAC AAGGCCATCA TCACAGAGGA TGGAAAAGTT 2460

AATGGAGTGA CGGATTCAAC ACGGATACTG GGTTATACAT TTCTTCACCC AAGCGTCACC 2520

CCCCGGCCGC ATGTACAGTC TGTTACTCTA ACACCACAGG ACGAATTCTT CATCCTAGGA 2580

AGCAAGGGTT TGTGGGATAG CCTTTCAATG GAGGAAGCTG TTGAAACAGT GAGGAATGTA 2640

CCAGATGCCC TGGCAGCTTC TAAGAAGTTG TGCAGCTTAG CCCAAAGCTA TGGGTGCAGC 2700

GGTAGTTTGT GTGCAGTGGT GGTGCAGCTA AATGTCACTG AAGACTGTAT TTGCTGCTGT 2760

GAGCTAAATG GCGGCATGCC ACCTCCCAGC CCTGGAATTT TTACCCCATC TGTCAACGTG 2820

GTTATCAAGG ACCGGGCCCC TGACAGCCTT GGCATGCCAT CTTCCAGTAG TGGCTTAGCC 2880

TCAGAAATAA GCAGTGAGAT ATCCACTTCA GAGATGAGTA GTGAAGTTGG GTCGACTGCT 2940

TCTGATGAAC CCCCTGCAGT TTCTCTTCAT GAAAATGGAG TGGGTCCTGT TGGTTGTCCA 3000

ACTGAGCAGC GTTGTACTCT ACATCCAGTC TGTCTTTCAA GTTCCTTCCA GAGACAGCTC 3060

TCTAGTGCAA CGTTCTCTAG TGCCTTCTCT GACAATGGAC TGGACAGTGA AGATGAGGAG 3120

CCAATAGAAG GTGTCTTCTC TAATGGGAGC CGAGTGGAGG TAGAAGTGGA TATCCATTGT 3180

TCTCGAACAA AGTCTGGATG CCAGACTGTA CCTGCAGTAC TTACAGAGTC TACCGACGAG 3240

GGTATTGTCA TCAATGGCAA TGAGGATGAC ATGGGAGGTC CTGGTAAGAG ACAAGACTTT 3300

TCCTCAAATA CTCTCGGTCG ACAGAGAAGA GGCAATGGTT CAGTTGCACC CTTAGAAAAG 3360

AGCCACAACC TTATTGAAAT TGCAGCAGAT GCTCCTCTTA GAAAGCAAGG GGGCTATTTT 3420

GCAGCCCCTG CCCAGCCTGA TCCTGATGAC CAATTCATTA TACCTCCTGA ACTGGAGGAA 3480

GAAGTTAAGG AGATTATG 3498

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +++++ a+ +++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 663   SHGYAEASGVKSKLCVASLLVNNFCDNREA-----VYGVFDGERNVEVPSLLQCTMSDIL  717

         6899**********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         a el+    +++  ++++ ++Fl ++++l       ++ +k G +av+++ik++

Q: 718   ADELQ----KTKSEEEYMGNTFLVMQRKL------GTAGQKLGGSAVLCHIKHDpmdpag  767

         ***99....8999999*************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l++anvG++++v+cr+gk+++ls+  ++s+e+El+Ri+++++ ++++   +v+Gv+

Q: 768   cfTLTTANVGKCQTVICRDGKPLNLSKHLTVSCEEELKRIKQHKAIITEDG--KVNGVTD  825

         ********************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p vtp+P+v+s++lt++def+iL+s+Glwd +s eeav+ vr+v +

Q: 826   STRILGYTFLHPSVTPRPHVQSVTLTPQDEFFILGSKGLWDSLSMEEAVETVRNVPD---  882

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +a+kkL+ la+++g++ ++ a+vv

Q: 883   -ALAASKKLCSLAQSYGCSGSLCAVVV  908

         .******************99999987

Domain Sequence
(FASTA)

SHGYAEASGV KSKLCVASLL VNNFCDNREA VYGVFDGERN VEVPSLLQCT MSDILADELQ 60

KTKSEEEYMG NTFLVMQRKL GTAGQKLGGS AVLCHIKHDP MDPAGCFTLT TANVGKCQTV 120

ICRDGKPLNL SKHLTVSCEE ELKRIKQHKA IITEDGKVNG VTDSTRILGY TFLHPSVTPR 180

PHVQSVTLTP QDEFFILGSK GLWDSLSMEE AVETVRNVPD ALAASKKLCS LAQSYGCSGS 240

LCAVVV 246

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>