EKS-XET-00333

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00333

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	255.0	7.2E-76	137	390	254

Status

Unreviewed

Ensembl Protein

ENSXETP00000063487

UniProt Accession

F7EJN8;

Protein Name

Protein Synonyms/Alias

Gene Name

PASK

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000032412	ENSXETP00000063487	ENSXETT00000062053
ENSXETG00000032412	ENSXETP00000060016	ENSXETT00000063137

Organism

Xenopus tropicalis

Functional Description

Protein Length

404

Protein Sequence
(FASTA)

PCPSAVGVSP PITVQVTRLP GSPSFLSEIR EGIFNGSCYH RDGSRLFIQF DVQRTVSAGS 60

YLFNVWVSKD LLQSQRDAIA RTRLLLSSFA SSSQSLLEQS ERSLGELIRN SANAGYCTEL 120

QDLQIVGACN GQYALKYQTV SPLGKGAFGF VWSACGRDSA KEEVVVKFIR KDRVLDDCWV 180

QDPELGKVTQ EIAILSRVQH PNIIRVVDVF ENDTFFQLVM ELHGDGLDLF DFIDSQPSLD 240

EPLASYIFRQ LVSAVGYLHN QHILHRDIKD ENIIIAPDFS IKLVDFGSAA HLHQGTLFST 300

FCGTTEYCAP EVLLGNPYPG PELEMWSLGV TLYTLIFGEN PFCEVDEILE AELNPPFNVS 360

QKLQVLISGL LQRDPEIRMT LDELLRDPWV TQPINLAEYT WEEV 404

Nucleotide Sequence
(FASTA)

CCATGCCCTT CGGCTGTAGG TGTCTCTCCT CCAATTACGG TGCAGGTTAC CCGTCTACCA 60

GGTAGCCCAT CATTTCTGAG TGAAATACGA GAAGGAATAT TTAATGGCAG TTGTTACCAC 120

CGGGATGGCT CCAGACTTTT CATTCAGTTT GATGTACAGA GGACAGTCTC GGCTGGCTCC 180

TACCTGTTTA ATGTTTGGGT GTCTAAAGAT CTGCTGCAAA GTCAGAGAGA CGCTATAGCT 240

CGGACCAGAC TTTTGCTATC TAGTTTTGCA AGCTCTTCTC AGTCTCTTCT GGAACAGTCA 300

GAGCGCAGCC TAGGAGAGCT GATCCGTAAC AGTGCAAATG CAGGGTACTG TACAGAGTTA 360

CAGGATCTCC AGATTGTGGG TGCCTGCAAC GGGCAATACG CCTTGAAATA CCAAACAGTA 420

TCCCCTCTAG GAAAAGGCGC TTTTGGGTTT GTGTGGTCTG CATGTGGCAG GGACAGTGCT 480

AAAGAGGAGG TTGTTGTAAA GTTTATTCGC AAAGATCGAG TACTGGATGA CTGCTGGGTA 540

CAGGATCCTG AACTTGGAAA GGTCACCCAG GAAATTGCAA TTCTGTCACG GGTACAACAT 600

CCAAATATAA TTAGGGTTGT GGATGTGTTT GAGAATGATA CATTCTTCCA GCTGGTAATG 660

GAACTTCATG GCGATGGTCT GGACCTTTTT GACTTTATTG ATAGTCAGCC CAGTCTGGAT 720

GAGCCACTAG CCAGTTACAT ATTTCGACAG CTTGTCTCAG CAGTGGGCTA TCTTCACAAT 780

CAACATATTC TGCATCGGGA TATTAAAGAT GAAAATATCA TTATTGCACC AGACTTTAGT 840

ATAAAACTGG TTGATTTTGG CTCTGCTGCC CATTTACATC AAGGAACCCT CTTCTCCACA 900

TTTTGTGGGA CCACAGAATA CTGTGCCCCA GAGGTGTTAC TTGGAAACCC GTACCCTGGT 960

CCAGAACTGG AGATGTGGTC TCTTGGTGTG ACTTTATACA CCCTCATTTT TGGGGAAAAT 1020

CCTTTCTGTG AAGTTGACGA AATATTAGAA GCAGAACTAA ACCCTCCATT TAATGTATCA 1080

CAAAAGTTGC AGGTTCTGAT CTCTGGTCTT CTTCAACGTG ACCCAGAAAT CCGGATGACT 1140

CTGGACGAAC TGCTCAGGGA TCCATGGGTG ACACAACCTA TAAACCTTGC AGAGTATACA 1200

TGGGAGGAGG TA 1212

Domain Profile

S: 1     ykllktlGegsfgkVklakhk.etkekvavKiikkkkl......seeslekikrEieilk  53

         y++++ lG+g+fg V  a+ + + ke+v+vK+i+k+++      ++ +l k+++Ei+il+

Q: 137   YQTVSPLGKGAFGFVWSACGRdSAKEEVVVKFIRKDRVlddcwvQDPELGKVTQEIAILS  196

         89999************999868899**********999999998889************

S: 54    klkhpniikllevietkkklylvle.yasggeLfdyieekgrlkekearklfkqlvsavk  112

         +++hpnii++++v+e++++++lv+e + +g +Lfd i ++ +l+e  a+ +f+qlvsav

Q: 197   RVQHPNIIRVVDVFENDTFFQLVMElHGDGLDLFDFIDSQPSLDEPLASYIFRQLVSAVG  256

         *************************667788*****************************

S: 113   YlhskgivHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgk  172

         Ylh+++i HrD+K eN+++  + +ik++DFG a+++++g+l++tfcG+++Y+aPe+l g+

Q: 257   YLHNQHILHRDIKDENIIIAPDFSIKLVDFGSAAHLHQGTLFSTFCGTTEYCAPEVLLGN  316

         ************************************************************

S: 173   kYegpkvDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrkl  232

         +Y gp++++WslGv+Ly+l++g+ Pf e       ++il+ +l+ p+++s++l+ L++ l

Q: 317   PYPGPELEMWSLGVTLYTLIFGENPFCEV------DEILEAELNPPFNVSQKLQVLISGL  370

         ***************************98......79***********************

S: 233   LvvdpekRatieeilkhewl  252

         L++dpe R+t++e+l+++w+

Q: 371   LQRDPEIRMTLDELLRDPWV  390

         *******************7

Domain Sequence
(FASTA)

YQTVSPLGKG AFGFVWSACG RDSAKEEVVV KFIRKDRVLD DCWVQDPELG KVTQEIAILS 60

RVQHPNIIRV VDVFENDTFF QLVMELHGDG LDLFDFIDSQ PSLDEPLASY IFRQLVSAVG 120

YLHNQHILHR DIKDENIIIA PDFSIKLVDF GSAAHLHQGT LFSTFCGTTE YCAPEVLLGN 180

PYPGPELEMW SLGVTLYTLI FGENPFCEVD EILEAELNPP FNVSQKLQVL ISGLLQRDPE 240

IRMTLDELLR DPWV 254

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0004871	; F:signal transducer activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000014	; PAS.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00091	; PAS; 3.
SM00220	; S_TKc; 1.

Prosites

PS50112	; PAS; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013