EKS-XET-00539

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-XET-00539

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	483.0	2.8E-145	162	419	258

Status

Unreviewed

Ensembl Protein

ENSXETP00000059412

UniProt Accession

F6PPN1;

Protein Name

Protein Synonyms/Alias

Gene Name

sgk3

Gene Synonyms/Alias

sgk3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSXETG00000033505	ENSXETP00000059412	ENSXETT00000063875

Organism

Xenopus tropicalis

Functional Description

Protein Length

496

Protein Sequence
(FASTA)

VYSYNPMEPK SNCPSVRIPS YNEQRQNRKR FTVYKVIVSM GRNEWFVFRR YAEFDKLYNT 60

LRKQYPHMNL KIPAKRIFGD NFDPDFIQQR RAGLNEFIQN LLRHSELCSH SDVQSFLQLD 120

SPKHQSDPSE DEDERVDQKN GSASRDVNLG PSGNPHAKPS DFEYLKLIGK GSFGKVVLTR 180

GKRDGRYYAV KVLQKNVILN KKEQRHIMAE RNVLLKNVKH PFLVTLHYSF QTSDKLFFVL 240

DFINGGELFF HLQRERYFAE PRALFYAAEI GSALGYLHSI DIIYRDLKPE NILLDSQGHI 300

VLTDFGLCKE GISNSDTTLT FCGTPEYLAP EVIVKQPYDN TVDWWCLGSV LYEMLHGLPP 360

FYNRDTATMY ENILHKPLTT RPDISLPAIS ILEELLEKDP KLRLGVNNDF QDIKNHAFFA 420

SINWADLVEK KMTPPYDPHV NGPDDISNFD KEFTEEMVPY SVCVSSDYSI VNASVEEADD 480

AFVGFSYAPP SDDFFY 496

Nucleotide Sequence
(FASTA)

GTTTACAGTT ACAACCCAAT GGAACCGAAG TCCAATTGCC CAAGTGTAAG AATCCCCAGC 60

TATAATGAGC AGCGCCAAAA TAGGAAGAGA TTTACAGTTT ACAAGGTTAT AGTGTCAATG 120

GGGCGAAATG AGTGGTTTGT TTTCCGACGA TATGCAGAGT TTGATAAACT TTATAACACA 180

CTTAGAAAAC AGTACCCACA TATGAACTTG AAGATTCCTG CAAAGAGGAT TTTCGGTGAT 240

AATTTTGATC CAGACTTTAT CCAGCAAAGA AGAGCAGGAT TAAATGAATT TATTCAGAAT 300

TTACTTCGTC ATTCAGAATT ATGCAGCCAC TCTGATGTCC AGTCCTTCCT TCAACTGGAC 360

TCTCCAAAGC ATCAATCAGA TCCTTCAGAG GATGAAGATG AAAGAGTTGA TCAAAAGAAT 420

GGTTCTGCTT CACGAGATGT CAACCTGGGA CCCTCTGGAA ACCCTCATGC CAAGCCTTCC 480

GATTTTGAAT ACCTCAAACT GATTGGAAAA GGAAGCTTTG GGAAGGTTGT ACTTACTAGA 540

GGGAAGCGTG ATGGACGTTA TTATGCAGTC AAAGTGTTAC AGAAGAATGT TATTCTTAAC 600

AAGAAAGAGC AAAGACACAT CATGGCTGAA CGAAACGTGC TTTTGAAAAA TGTGAAACAT 660

CCATTTTTAG TGACGCTACA CTATTCCTTT CAGACATCTG ACAAGTTGTT TTTTGTCCTG 720

GATTTTATAA ATGGAGGAGA GCTTTTTTTC CACTTACAAA GAGAGCGATA TTTTGCAGAG 780

CCCAGAGCTC TGTTCTACGC TGCAGAGATC GGCAGTGCTT TGGGCTATTT GCATTCCATC 840

GATATCATAT ACAGGGACTT AAAACCTGAA AATATTCTTC TGGATTCTCA GGGTCATATT 900

GTATTAACTG ATTTTGGTCT ATGCAAGGAA GGAATTTCCA ATTCTGACAC AACGCTCACC 960

TTTTGTGGGA CACCGGAGTA TCTAGCACCT GAGGTTATAG TGAAACAACC ATATGACAAC 1020

ACAGTGGATT GGTGGTGCCT TGGCTCTGTC CTGTATGAAA TGCTGCATGG ACTACCACCT 1080

TTTTATAACC GTGACACAGC TACAATGTAT GAGAATATTC TTCACAAGCC CCTGACTACA 1140

AGGCCTGACA TAAGTTTGCC TGCAATATCA ATCTTGGAAG AACTGCTTGA GAAGGACCCC 1200

AAGCTGAGAC TGGGCGTTAA TAACGATTTT CAAGACATTA AGAATCATGC ATTTTTTGCC 1260

TCTATAAACT GGGCTGATCT AGTTGAAAAG AAGATGACGC CACCTTATGA TCCCCACGTG 1320

AATGGCCCTG ACGATATATC AAATTTTGAT AAAGAATTCA CAGAAGAAAT GGTGCCATAT 1380

TCAGTCTGTG TGTCTTCTGA CTATTCAATC GTGAATGCCA GCGTGGAAGA GGCAGATGAC 1440

GCATTTGTGG GATTTTCTTA TGCACCTCCC TCCGATGACT TTTTCTATTA G 1491

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         f++lk igkgsfgkv+l++ k d+++yavkvlqk+ il+kke++himaernvllknvkhp

Q: 162   FEYLKLIGKGSFGKVVLTRGKRDGRYYAVKVLQKNVILNKKEQRHIMAERNVLLKNVKHP  221

         89**********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flv+lhysfqt++kl+fvld++nggelffhlqrer f+epra fyaaei salgylhs++

Q: 222   FLVTLHYSFQTSDKLFFVLDFINGGELFFHLQRERYFAEPRALFYAAEIGSALGYLHSID  281

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         i+yrdlkpenillds+gh+vltdfglcke+i ++dtt tfcgtpeylapev+ k+pyd+t

Q: 282   IIYRDLKPENILLDSQGHIVLTDFGLCKEGISNSDTTLTFCGTPEYLAPEVIVKQPYDNT  341

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclg+vlyeml+glppfy+rd+a my+nil+kpl  +p+is++a+++leellekd k

Q: 342   VDWWCLGSVLYEMLHGLPPFYNRDTATMYENILHKPLTTRPDISLPAISILEELLEKDPK  401

         ************************************************************

S: 241   krlgakedfleiknhvff  258

          rlg ++df +iknh ff

Q: 402   LRLGVNNDFQDIKNHAFF  419

         *****************9

Domain Sequence
(FASTA)

FEYLKLIGKG SFGKVVLTRG KRDGRYYAVK VLQKNVILNK KEQRHIMAER NVLLKNVKHP 60

FLVTLHYSFQ TSDKLFFVLD FINGGELFFH LQRERYFAEP RALFYAAEIG SALGYLHSID 120

IIYRDLKPEN ILLDSQGHIV LTDFGLCKEG ISNSDTTLTF CGTPEYLAPE VIVKQPYDNT 180

VDWWCLGSVL YEMLHGLPPF YNRDTATMYE NILHKPLTTR PDISLPAISI LEELLEKDPK 240

LRLGVNNDFQ DIKNHAFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.
PF00787	; PX; 1.

SMARTs

SM00312	; PX; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013